Clinical trials: Abortion, Spontaneous
Abortion, Spontaneous
Interleukin-10 Promoter-1082A/G Polymorphism and Idiopathic Recurrent Miscarriage Risk
This study aimed to assess the correlation between the interleukin-10 (IL-10)-1082A/G polymorphism and idiopathic recurrent miscarriage (IRM) of Chinese Han.
- Trial name
- NCT02633475
- Testing
- IL-10 polymorphism
- Where
- 2 sites in China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Fourth Affiliated Hospital of Guangxi Medical University
Preterm Birth Complication, Preterm Birth
Personalized Care for Prenatal Stress Reduction & Prevention of Preterm Birth (PTB) Disparities
The goal of this clinical trial is to learn if a personalized prenatal support program [(Personalized Toolkit Building a Comprehensive Approach to Resource optimization and Empowerment in Pregnancy \& Beyond, (PTBCARE+)] works to…
- Conditions
- Preterm Birth Complication, Preterm Birth, Preterm Birth Recurrence, Preeclampsia
- Trial name
- PTBCARE+ (NCT06915428)
- Testing
- Care coordination, Electronic massage, support gift #1
- Where
- United States
- Volunteers
- 1,228 people
- Sponsor
- University of North Carolina, Chapel Hill
Miscarriage, Recurrent, Premature Labor
PAR Family Polymorphisms and Placental Invasion Disorders
The present study will be undertaken to establish whether genetic variations of PAR1 could be involved in the occurrence of any of the "placental syndromes" of preterm delivery, preeclampsia, and/or small for gestational age…
- Trial name
- NCT00425867
- Testing
- PAR1 polymoprhisms and placental invasion
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Shaare Zedek Medical Center
Retained Products of Conception
Removal of Intrauterine Retained Products of Conception (RPOC) After Miscarriage Guided by Hysteroscopy Trial. A Randomized Controlled Trial.
Rationale: Elective immediate dilation and curettage (D\&C) for miscarriage is associated with the occurrence of intrauterine adhesions (IUA). IUAs may be associated with subsequent subfertility and premature birth.
- Trial name
- RIGHT (NCT04804332)
- Testing
- Operative hysteroscopy, Expectant management
- Where
- Belgium
- Volunteers
- 244 people
- Sponsor
- University Hospital, Ghent
Recurrent Abortion
Low-molecular-weight Heparin (LMWH) Versus Unfractionated Heparin (UFH) in Pregnant Women With Recurrent Abortion Secondary to Antiphospholipid Syndrome
The aim of this study is to compare the efficacy and safety of Low molecular weight heparin (LMWH) plus low dose aspirin (LDA) with unfractionated heparin(UFH) plus LDA in women with recurrent pregnancy loss associated with…
- Trial name
- NCT01051778
- Testing
- enoxaparin 40mg plus low dose aspirin, Heparin calcium5,000 U twice daily plus low dose aspirin
- Where
- 2 sites in Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Spontaneous Abortion, Oxidative Stress
Heavy Metals' Influence on Early Pregnancy Through Oxidative Stress
Patients with diagnosis of spontaneous abortion are enrolled in the cohort, in the cohort of patients who met the criteria, 3ml of whole blood intravenous and 5ml of urine were taken for heavy metal level examnation.
- Trial name
- NCT04003064
- Testing
- Blood
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Peking Union Medical College Hospital
Hypofibrinogenemia, Congenital, Afibrinogenemia, Congenital
Pregnancy and Fibrinogen Disorders
The aim of this observational study is to evaluate the prevalence of uncomplicated pregnancies in women suffering from congenital fibrinogen disorders (i.e, hypofibrinogenemia, dysfibrinogenemia, hypodysfibrinogenemia) as well as…
- Conditions
- Hypofibrinogenemia, Congenital, Afibrinogenemia, Congenital, Dysfibrinogenemia, Congenital
- Trial name
- FIBRINOGEST (NCT03920332)
- Where
- 3 sites in France, Slovakia and 1 more
- Volunteers
- 149 people
- Sponsor
- University Hospital, Geneva
Retained Products of Conception, Hysteroscopy
Predictors of Successful Office Operative Hysteroscopy Using a Mini-Resectoscope
The goal of this observational study is to identify predictors of successful removal of benign intrauterine pathology using a mini-resectoscope during office operative hysteroscopy without anesthesia in adult women with suspected…
- Conditions
- Retained Products of Conception, Hysteroscopy, Endometrial Polyp Benign, Endometrial Polyp
- Trial name
- NCT07875985
- Testing
- Office Operative Hysteroscopy Using the Karl Storz Mini-Resectoscope Without Anesthesia
- Where
- Israel
- Volunteers
- 50 people
- Sponsor
- Shaare Zedek Medical Center
Spontaneous Abortions, Infertility
Molecular Associations With Reproductive Failure
The overall hypothesis to be tested is: women with the molecular phenotype of highly skewed X chromosome inactivation are at increased risk of spontaneous abortion.
- Trial name
- NCT00298116
- Where
- United States
- Volunteers
- 475 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Cervical Insufficiency, Preterm Birth
Optimal Timing of Routine Cervical Length Measurements During Anatomy Survey
The goal of this clinical trial is to determine the optimal timing for measuring cervical length (CL) during fetal anatomy surveys in pregnant individuals.
- Conditions
- Cervical Insufficiency, Preterm Birth, Cervical Length Measurement
- Trial name
- NCT06822647
- Testing
- Cervical Length Measurement at the Beginning of the Anatomy Survey, Cervical Length Measurement at the End of the Anatomy Survey
- Where
- United States
- Volunteers
- 550 people
- Sponsor
- Henry Ford Health System
Previous Mid Trimester Miscarriage, Previous Preterm Birth
Arabin Pessary in Singleton Pregnancy
This was a retrospective study sharing the experience of women high risk for spontaneous preterm birth managed by Arabin pessary.
- Conditions
- Previous Mid Trimester Miscarriage, Previous Preterm Birth, Previous Cervical Surgery, Short Cervix on Ultrasound
- Trial name
- NCT04638023
- Testing
- Arabin pessary
- Where
- Malaysia
- Volunteers
- 58 people
- Sponsor
- National University of Malaysia
Pregnancy Loss
ACTRAMAT-D: Impact of Post-Traumatic Stress Disorder After Pregnancy Loss After 12 Weeks of Gestation
In France The prevalence of Pregnancy Loss after 12 weeks of gestation is around 3%. This situation is probably associated to a risk of post-traumatic stress disorder.
- Trial name
- ACTRAMAT-D (NCT03433989)
- Testing
- telephone interview
- Where
- France
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- University Hospital, Angers
Miscarriage
Sublingual Versus Vaginal Misoprostol In Medical Treatment of Second Trimestric Missed Miscarriage
The aim of this work is to compare the effectiveness of vaginal versus sub-lingual misoprostol for medical treatment of the second trimester missed miscarriage
- Trial name
- NCT05088707
- Testing
- sublingual misoprostol, vaginal misoprostol
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Aswan University Hospital
Missed Abortion, Pregnancy
Mifepristone and Misoprostol Versus Misoprostol Alone for Missed Abortion: A Randomized-controlled Trial
The purpose of the proposed study is to compare - in a randomized, placebo-controlled, double-blinded trial - a combination of mifepristone and misoprostol to misoprostol used alone for missed abortion.
- Trial name
- NCT02342002
- Testing
- Mifepristone, Misoprostol
- Where
- 4 sites in Argentina, Gabon and 2 more
- Volunteers
- 416 people, healthy volunteers welcome
- Sponsor
- Gynuity Health Projects
Cervical Incompetence in Pregnancy as Antepartum Condition
Hyperbaric Prilocaine Compared With Hyperbaric Bupivacaine in Cervical Cerclage?
Patients that have a "cervical stitch" (cervical cerclage) require an anaesthetic. The most common choice is a spinal block. This is an injection in the back that makes the lower half of the body become temporarily numb and weak.
- Trial name
- PRILOCC (NCT04394533)
- Testing
- Prilocaine (Hyperbaric 2%), Bupivacaine (Hyperbaric 0.5%)
- Where
- United Kingdom
- Volunteers
- 129 people
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Miscarriage, Recurrent
Unexplained Recurrent Pregnancy Loss: New Therapeutic Perspectives
Evaluation of gut permeability and endometrial inflammasome NLRP3 in women with unexplaid recurrent pregnancy loss before-after administration of Bifidobacteriumlongum ES1.
- Trial name
- NCT06867900
- Testing
- Bifidobacterium Longum ES1
- Where
- Italy
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Spontaneous Abortion
Knowledge, Attitude and Practices of Flemish Midwifes Regarding Spontaneous Abortion
KAP-study in Flemish midwives with intramural employment
- Trial name
- KAP-abortion (NCT02657200)
- Testing
- survey
- Where
- Belgium
- Volunteers
- 647 people, healthy volunteers welcome
- Sponsor
- VakgroepVolksgezondheidEnEerstelijnszorg
Recurrent Miscarriage, First Trimester Abortion
Hydroxychloroquine for Prevention of Recurrent Miscarriage.
Recurrent miscarriage (RM) defined by >=3 consecutive losses affects 1% of fertile couples. Most women have recurrent early loss with a failure of development before 10 weeks' gestation.
- Trial name
- BBQ (NCT03165136)
- Testing
- Hydroxychloroquine
- Where
- 18 sites in France
- Volunteers
- 300 people
- Sponsor
- University Hospital, Brest
Arcuate Uterus
A Randomised Controlled Trial of Hysteroscopic Resection of Mild Septum/Arcuate Uteri.
At least 82 cases of recurrent miscarriage women with a diagnosis of arcuate uterus, confirmed by three-dimensional intra-vaginal sonography (3D-TVS) and hysteroscopy, will be recruited.
- Trial name
- NCT03384082
- Testing
- hysteroscopic treatment
- Where
- China
- Volunteers
- 82 people
- Sponsor
- Fu Xing Hospital, Capital Medical University
Missed Abortion
Effects of Mandala Coloring in Missed Abortion
This randomized controlled study aims to evaluate the effects of mandala coloring activity on stress, anxiety, pain, and physiological parameters in women diagnosed with missed abortion.
- Trial name
- NCT07420413
- Testing
- Mandala Coloring Activity
- Where
- Turkey (Türkiye)
- Volunteers
- 126 people
- Sponsor
- Selcuk University