Clinical trials: Abortion, Therapeutic
Pregnancy of Unknown Location
Hysteroscopy for the Diagnosis and Treatment of Pregnancy of Unknown Location
Infertility patients have a higher baseline risk of ectopic pregnancy compared to the general population. If an early pregnancy is not visible by ultrasound, patients with a pregnancy of unknown location (PUL) will undergo…
- Trial name
- NCT07469605
- Testing
- Hysteroscopy for diagnosis and treatment of pregnancy of unknown location
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Pennsylvania
Medical; Abortion, Fetus
Evaluation of Efficacy of Two Therapeutic Strategies for Cervical Maturation Before Medical Termination
Reducing the time patients spend in the labor and delivery room saves money and reduces patient discomfort as well and reducing complications.
- Trial name
- IMEGYN (NCT03194126)
- Testing
- Mifepristone + Misoprostol OR oxytocine + laminaria, Mifepristone + Misoprostol OR oxytocine
- Where
- 2 sites in France
- Volunteers
- 120 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Medical Abortion
Medical Abortion at Gestational Age of 8 to ≤9 Weeks Versus >9 to ≤12 Weeks
The purpose of this study is to assess the effectiveness, safety, and acceptability of home-administered medical abortion at gestational age of 8 to ≤9 weeks versus >9 to ≤12 weeks among a cohort of women in Mexico City.
- Trial name
- NCT02745093
- Testing
- Mifepristone, Misoprostol
- Where
- 3 sites in Mexico
- Volunteers
- 648 people
- Sponsor
- Ibis Reproductive Health
Abortion in First Trimester, Abortion Early
A Patient Decision Aid for Method of Early Abortion: a Randomized Control Trial
Introduction: There are two options for women seeking early pregnancy termination in Canada; either surgical or medication abortion.
- Conditions
- Abortion in First Trimester, Abortion Early, Decision Aid, Clinical Decision-making
- Trial name
- NCT05182008
- Testing
- Decision aid, Usual care
- Where
- Canada
- Volunteers
- 365 people, healthy volunteers welcome
- Sponsor
- Nova Scotia Health Authority
Recurrent Pregnancy Loss
Recurrent Pregnancy Loss and Thyroid Disease
The present study is divided into two groups ,one is the patients with subclinical hypothyroidism who has TPO antibody positive women with TSH concentrations > 2.5 mU/L and below the upper limit of the pregnancy specific…
- Trial name
- NCT03106935
- Testing
- Levothyroxine
- Where
- China
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital of Soochow University
Missed Abortion
Operative Hysteroscopy and Ultrasound Guided Vacuum Aspiration Versus Blind Vacuum Aspiration for the Treatment of Missed Abortion
The intervention to be evaluated are operative hysteroscopy(group A) and ultrasound guided aspiration(group C) and blinded vacuum aspiration(group B).
- Trial name
- NCT03081104
- Testing
- hystroscopy, ultrasound, Aspiration
- Where
- Egypt
- Volunteers
- 300 people
- Sponsor
- Cairo University
Vaginosis, Bacterial, Abortion, Spontaneous
Bacterial Vaginosis Screening and Treatment to Reduce Infective Complications, Abortion and Preterm Delivery
To determine whether screening of pregnant women with history of previous preterm delivery or with premature contractions for bacterial vaginosis using VS-SENSE, and treatment of positive women will reduce the risk of spontaneous…
- Conditions
- Vaginosis, Bacterial, Abortion, Spontaneous, Premature Birth
- Trial name
- NCT00491270
- Testing
- VS Sense
- Where
- Israel
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Western Galilee Hospital-Nahariya
Abortion, Missed
Testing the Efficiency of Karman Curette in the Treatment of Misoprostol Failure in Women With Missed Abortion
the purpose of this study is to examine the success rates of Karman curettage in completing the abortion after failed recurred treatment with Misoprostol for women with missed abortion.
- Trial name
- NCT02917785
- Testing
- Karman curettage
- Where
- Israel
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Meir Medical Center
Miscarriage, Recurrent, Abortion, Habitual
Intravenous Immunoglobulin (IVIG) for Treatment of Unexplained Secondary Recurrent Miscarriage
Recurrent miscarriage is a prevalent reproductive problem that affects many couples who are trying to establish a family. This clinical study will evaluate the effectiveness of intravenous immunoglobulin (IVIG) in improving the…
- Trial name
- NCT00606905
- Testing
- Gamimune N or Gamunex 10%, normal saline
- Where
- United States
- Volunteers
- 82 people
- Sponsor
- University of Chicago
Miscarriage
Treatment of Missed Miscarriage With TRUCLEAR Tissue Removal System, a Feasiblity Study
the Aim of this study is to prospectively study the feasibility of evacuation of products of conception (POC) in missed miscarriages up to 10 weeks using the TRUCLEAR tissue removal system in order to achieve targeted treatment…
- Trial name
- NCT04512820
- Testing
- TRUCLEAR tissue removal system
- Where
- Israel
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Assuta Ashdod Hospital
Abortion, Second Trimester
Induction of Abortion in the Second Trimester
To compare between the effects of misoprostol with hyoscine N-butyl bromide and misoprostol alone on shortening the time of abortion induction in the second trimester.
- Trial name
- NCT06207539
- Testing
- hyoscine N-butyl bromide under the generic name of buscopan ampoule produced by Sanofi company, misoprostol under the generic name of misotac tablets
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Ain Shams Maternity Hospital
Thrombophilia With Recurrent Pregnancy Loss
Diagnosis and Treatment Strategy of Recurrent Spontaneous Abortion Associated With Thrombophilla
In this clinical cohort study, the investigators observe the efficacy of low molecular weight heparin in the treatment of thrombophilia with recurrent pregnancy loss with a prospective randomized controlled trial.
- Trial name
- NCT02986594
- Testing
- Aspirin, Heparin
- Where
- China
- Volunteers
- 600 people
- Sponsor
- Shanghai First Maternity and Infant Hospital
Infertility, Miscarriage
International NaProTechnology Evaluation and Surveillance of Treatment for Infertility and Miscarriage (iNEST)
NaProTechnology (NPT) is a treatment option for infertility or miscarriage that identifies issues in a couple's fertility and fixes them to the extent possible by medical intervention.
- Trial name
- iNEST (NCT01363596)
- Testing
- Creighton Model System in conjunction with Natural Procreative Technology (NPT)
- Where
- 8 sites in United States, Canada and 2 more
- Volunteers
- 834 people
- Sponsor
- University of Utah
Frozen Embryo Transfer, Polycystic Ovarian Disease
Letrozole Versus Hormonal Preparation in Frozen Cycles of PCOS Patients.
One of the indications of freezing is to reduce the risk of ovarian hyperstimulation syndrome particularly in polycystic ovarian disease (PCOS) women.
- Conditions
- Frozen Embryo Transfer, Polycystic Ovarian Disease, Letrozole, Hormone Replacement Therapy
- Trial name
- NCT05168865
- Testing
- Letrozole 2.5mg
- Sponsor
- Dubai Fertility Center
Vaginosis, Bacterial, Infertility
Efficacy Study of Preconception Treatment of an Asymptomatic Bacterial Infection in an Infertility Population
Bacterial vaginosis (BV) is a common vaginal infection characterized by a pathologic shift in the normal vaginal flora. BV has been associated with a number of poor reproductive outcomes, including infertility, preterm labor and…
- Conditions
- Vaginosis, Bacterial, Infertility, Miscarriage
- Trial name
- NCT01322971
- Testing
- Metronidazole
- Where
- United States
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Stanford University
Abortion, Induced, Vomiting
Serum Levels of Doxycycline at the Time of Abortion With Two Dosing Regimens
This is a randomized double-blind, controlled trial comparing two regimens of pre-abortion doxycycline. The aims of the study are to determine the serum levels of doxycycline when administered pre-operatively 4 hours or…
- Trial name
- NCT00177333
- Testing
- Doxycycline
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Post-traumatic Stress Disorder, Stress Disorders
Effectiveness of Cognitive Processing Therapy in Pregnant Women With a History of Pregnancy Loss/Complication
The purpose of this study is to examine the effects of experiencing a previous pregnancy loss or complication on current physiological and emotional aspects of a current pregnancy.
- Conditions
- Post-traumatic Stress Disorder, Stress Disorders, Anxiety, Depression
- Trial name
- NCT01277354
- Testing
- Cognitive Processing Therapy
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- University of Pennsylvania
IVF Outcomes, Prediction Models
Machine-Learning Prediction of Pregnancy Outcomes After Assisted Reproductive Treatments
The goal of this observational study is to develop and validate a machine-learning model to predict pregnancy outcomes in women with a positive pregnancy test following assisted reproductive treatment (ART), with the primary…
- Conditions
- IVF Outcomes, Prediction Models, Infertility Assisted Reproductive Technology, Live Birth
- Trial name
- NCT07855783
- Testing
- Machine-Learning Model for Prediction of Pregnancy Outcomes
- Where
- 2 sites in Croatia
- Volunteers
- 2,200 people
- Sponsor
- BetaPlus Center for Reproductive Medicine
Incomplete Abortion
400mcg Sublingual Misoprostol as First Line Treatment
Women presenting with incomplete abortion and eligible for treatment with misoprostol were offered 400mcg sublingual misoprostol for treatment.
- Trial name
- NCT01939457
- Testing
- Misoprostol
- Where
- Senegal
- Volunteers
- 641 people, healthy volunteers welcome
- Sponsor
- Gynuity Health Projects
Pregnancy Related
Pharmacological Voluntary Termination of Pregnancy: Predictors of Pelvic Pain During Treatment
Pharmacological treatment for voluntary termination of pregnancy is a safe and effective practice, but has as its limitation a greater need for analgesic coverage than surgical treatment.
- Trial name
- NCT06800287
- Where
- 2 sites in Italy
- Volunteers
- 13 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna