Clinical trials: Abortion; Induced
Abortion in First Trimester
Transcutaneous Electrical Nerve Stimulation (TENS) for Pain Control During First Trimester Abortion
High-frequency, high-intensity transcutaneous electrical nerve-stimulation (TENS) is an inexpensive and non-invasive pain control approach.
- Trial name
- NCT03187002
- Testing
- Transcutaneous electrical nerve stimulation (TENS), Moderate IV Sedation
- Where
- United States
- Volunteers
- 109 people
- Sponsor
- Stanford University
Septic Abortion
Clindamycin Once a Day in Septic Abortion
Septic abortion is a serious condition. Women with septic abortion are treated with clindamycin plus gentamicin using divided doses, i.e., thrice a day.
- Trial name
- CLINDA-PRO (NCT02309346)
- Testing
- Clindamycin
- Where
- Brazil
- Volunteers
- 200 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Abortion Early
Auriculotherapy During Medication Abortion
This randomized trial will evaluate the effect of adding auriculotherapy (i.e. acupuncture applied to the ear) using either gold beads or Pyonex needles in addition to usual care for the relief of pain and anxiety during…
- Trial name
- NCT03900728
- Testing
- Auriculotherapy with needles, Auriculotherapy with beads
- Where
- United States
- Volunteers
- 138 people, healthy volunteers welcome
- Sponsor
- Columbia University
Abortion, Dilation and Evacuation
Effects of Oxytocin on Bleeding Outcomes During Dilation and Evacuation
Currently, there is very little research to identify ways to decrease blood loss during D\&E (dilation and evacuation) procedures.
- Conditions
- Abortion, Dilation and Evacuation, Hemorrhage, Blood Loss
- Trial name
- NCT02083809
- Testing
- intravenous oxytocin, Intravenous Fluids and Electrolytes
- Where
- 2 sites in United States
- Volunteers
- 166 people
- Sponsor
- University of Hawaii
Medical; Abortion, Fetus
Programmed Intermittent Epidural Bolus Versus Continuous Epidural Infusion for Termination of Pregnancy Analgesia
This study included women who underwent voluntary second trimester termination of pregnancy. Patients were randomized to programmed intermittent epidural anesthetic bolus or continuous epidural infusion for pain analgesia.
- Trial name
- NCT01860521
- Testing
- Programmed Intermittent Epidural Bolus, Continuous Epidural Infusion, Procedure of interruption of pregnancy
- Where
- Italy
- Volunteers
- 104 people
- Sponsor
- IRCCS Azienda Ospedaliera Universitaria San Martino - IST Istituto Nazionale per la Ricerca sul Cancro, Genoa, Italy
Abortion
Mifepristone Versus Laminaria Insertion for Cervical Preparation Prior to Surgical Abortion at 14-16 Weeks
Women who are requesting pregnancy termination at 14-16 weeks, who would normally have osmotic dilator insertion the day before their procedure, would be asked if they wanted to participate.
- Trial name
- SAMi (NCT00986921)
- Testing
- mifepristone 200 mg, osmotic dilator insertion
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Boston University
Contraception, Post-abortion Family Planning
Mobile Technology for Improved Family Planning
An individual randomised controlled trial (RCT) to evaluate the effectiveness of a voice-based mobile phone health (mHealth) intervention to support post-abortion family planning (PAFP) at four Marie Stopes International clinics…
- Conditions
- Contraception, Post-abortion Family Planning, mHealth
- Trial name
- MOTIF (NCT01823861)
- Testing
- Mobile phone-based intervention
- Where
- Cambodia
- Volunteers
- 500 people
- Sponsor
- Marie Stopes International
Abortion
Trial of Immediate Versus Delayed Initiation of Transdermal Hormonal Contraception After Therapeutic Abortion
This is a randomized, controlled trial investigating whether immediate versus standard, "Sunday Start", initiation of transdermal hormonal contraception (the patch) in post-abortion subjects can improve compliance and the…
- Trial name
- NCT00235547
- Testing
- timing of initiation of transdermal patch after an abortion
- Where
- United States
- Volunteers
- 298 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Lactation Suppressed, Second Trimester Abortion
Pharmacological Inhibition of Lactation After 16 to 20 Week Abortion
The goal of this clinical trial is to compare breast symptoms (lactation, engorgement, etc) of individuals who undergo a procedure for second trimester of pregnancy loss between 16 weeks and 20 weeks gestational age.
- Trial name
- NCT06123026
- Testing
- Cabergoline
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Vaginosis, Bacterial, Infertility
Efficacy Study of Preconception Treatment of an Asymptomatic Bacterial Infection in an Infertility Population
Bacterial vaginosis (BV) is a common vaginal infection characterized by a pathologic shift in the normal vaginal flora. BV has been associated with a number of poor reproductive outcomes, including infertility, preterm labor and…
- Conditions
- Vaginosis, Bacterial, Infertility, Miscarriage
- Trial name
- NCT01322971
- Testing
- Metronidazole
- Where
- United States
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Stanford University
Pregnancy Related, Abortion Early
Medication Abortion Via Pharmacy Dispensing
This mixed-methods study follows a prospective cohort of patients receiving Mifeprex ® (mifepristone) for medication abortion dispensed by pharmacists after undergoing standard clinical evaluation.
- Trial name
- NCT03320057
- Testing
- Mifepristone, Training on mifepristone dispensing
- Where
- 6 sites in United States
- Volunteers
- 326 people, healthy volunteers welcome
- Sponsor
- Daniel Grossman
Nausea, Pain
Prophylactic Analgesic and Antiemetic Regimen for Medical Abortion < 70 Days
Randomized trial which will aim to evaluate whether prophylactic use of ondansetron and ibuprofen will decrease side effects associated with medical abortion and increase patient satisfaction.
- Trial name
- NCT05819619
- Testing
- Prophylactic use of ibuprofen and ondansetron post misoprostol administration, Use of ibuprofen and ondansetron at symptom onset post misoprostol administration
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Hackensack Meridian Health
Miscarriage, Stillbirth
Follow-up of Pregnant Women After a Mass Vaccination of Oral Cholera Vaccine (ShancholTM) in Nsanje Malawi
This study, to be carried out immediately following an emergency, reactive cholera vaccination campaign in Nsanje District, Malawi, will be a cohort study to estimate the safety of killed oral cholera vaccine (OCV), in pregnant…
- Conditions
- Miscarriage, Stillbirth, Cholera
- Trial name
- NCT02499172
- Testing
- Shanchol
- Where
- United States
- Volunteers
- 2,758 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Pain
Lidocaine and Pain Management in First Trimester Abortions
The purpose of this study is to examine the effect of lidocaine (a numbing medication) inside the uterus on patient pain during an early abortion, compared to the paracervical block (lidocaine injected on either side of the…
- Trial name
- NCT00613821
- Testing
- Lidocaine
- Where
- 2 sites in United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Pain
12 Versus 20 mL PCB for D&E Cervical Prep
More research is needed to investigate methods of pain control for cervical preparation for abortion procedures. Women report pain with paracervical block injection as well as with osmotic dilator placement.
- Trial name
- NCT03356145
- Testing
- 12 mL paracervical block, 20 mL paracervical block
- Where
- United States
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Stanford University
Recurrent Miscarriage, Spontaneous Abortion
Low Plasma Mannose Binding Lectin (p-MBL) Level is a Risk Factor for Recurrent Pregnancy Loss (RPL)
The present study is based on the hypothesis, that recurrent pregnancy loss (RPL) is associated with abnormal plasma mannose binding lectin (p-MBL) level.
- Conditions
- Recurrent Miscarriage, Spontaneous Abortion, Mannose-Binding Lectin Deficiency, Habitual Abortion
- Trial name
- NCT04017754
- Where
- Denmark
- Volunteers
- 452 people
- Sponsor
- Aalborg University Hospital
Abortion, Blood Loss
Effect of Preoperative Buccal Misoprostol on Blood Loss in Second-trimester Dilation and Evacuation Abortion
Misoprostol is a medication used extensively in obstetrics and gynecology for its ability to aid in softening the cervix as well as decreasing blood loss after abortion or vaginal delivery.
- Trial name
- PreopMiso (NCT01436266)
- Testing
- Misoprostol, Folic acid
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Boston University
Abortion in First Trimester
Pharmacist Provision of Medication Abortion
This will be a pilot study among two pharmacists providing start to finish medication abortions to 10 patients utilizing a previously created toolkit.
- Trial name
- NCT04956731
- Testing
- Pharmacist Provision of Medication Abortion
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Abortion Early
Transabdominal and Transvaginal Sonography in Medical Abortion
The investigator will perform a multicenter, randomized controlled trial in practices that routinely use transvaginal sonography (TVS) to compare how often clinicians order additional testing prior to medical abortion after the…
- Trial name
- TASvTVS (NCT03047551)
- Testing
- Transabdominal sonography, Transvaginal sonography
- Where
- 2 sites in United States
- Volunteers
- 634 people, healthy volunteers welcome
- Sponsor
- Columbia University