Clinical trials: Abortion in First Trimester
Abortion in First Trimester, Abortion Early
A Patient Decision Aid for Method of Early Abortion: a Randomized Control Trial
Introduction: There are two options for women seeking early pregnancy termination in Canada; either surgical or medication abortion.
- Conditions
- Abortion in First Trimester, Abortion Early, Decision Aid, Clinical Decision-making
- Trial name
- NCT05182008
- Testing
- Decision aid, Usual care
- Where
- Canada
- Volunteers
- 365 people, healthy volunteers welcome
- Sponsor
- Nova Scotia Health Authority
Effect of Drug
Analgesia From Conscious Sedation Versus Paracervical Block for Manual Vacuum Aspiration
Miscarriage is one of the major causes of early pregnancy losses. Incomplete miscarriage is a major cause of maternal morbidity and mortality.
- Trial name
- NCT06539143
- Testing
- Lidocaine
- Where
- Nigeria
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Darlington-Peter Chibuzor Ugoji
Legal Abortion With Complication, Pain
Paracervical Block for Pain Control in First Trimester Abortion
Many woman undergoing a surgical abortion receive a paracervical nerve block for pain reduction, in which lidocaine (a numbing medication) is injected around the cervix.
- Trial name
- NCT01094366
- Testing
- Paracervical Block
- Where
- United States
- Volunteers
- 121 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Fibroid, Miscarriage in First Trimester
Fibroids and the Risk of Miscarriage: a Prospective Observational Study in an Early Pregnancy Population
The aim of this observational study is to whether fibroids increase the risk of miscarriage in women in our early pregnancy population.
- Conditions
- Fibroid, Miscarriage in First Trimester, Miscarriage in Second Trimester
- Trial name
- FiRM (NCT06986616)
- Where
- United Kingdom
- Volunteers
- 436 people, healthy volunteers welcome
- Sponsor
- King's College Hospital NHS Trust
Pain
4% Intrauterine Lidocaine Infusion for Pain Management in First Trimester Abortions
Recent studies have investigated the use of local anesthetics (i.e. lidocaine, mepivacaine) to lessen the pain experienced with minor gynecologic procedures such as endometrial biopsy and office hysteroscopy.
- Trial name
- NCT00121329
- Testing
- Intrauterine lidocaine infusion 4%
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Contraception
Intrauterine Contraception After First Trimester Abortion - Effects on Quality of Life and Risk of Repeat Abortion.
A randomized prospective study on the effects of immediate provision of intrauterine contraception after first trimester induced abortion - effects on repeat abortions and quality of life.
- Trial name
- NCT01223521
- Testing
- Immediate intrauterine contraception
- Where
- Finland
- Volunteers
- 748 people, healthy volunteers welcome
- Sponsor
- Helsinki University Central Hospital
Infertility, Female, First Trimester Spontaneous Abortion
Determination of Circulating Placental Biomarkers Levels to Predict the Pregnancy Outcome of First Trimester After IVF.
This study will assess the predictive potential of circulating placental biomarkers for spontaneous miscarriage within the following month in an IVF setting.
- Trial name
- NCT04387994
- Testing
- Blood samples collection
- Where
- Portugal
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Instituto Valenciano de Infertilidade de Lisboa
First Trimester Abortion
Unexplained Early Miscarriage : Role and Prevalence of Lower Genital Tract Infections
The study group included 910 women who attended Fayoum university hospital gynecology outpatient clinic for postabortive evaluation.
- Trial name
- NCT03413774
- Testing
- vaginal swab
- Where
- Egypt
- Volunteers
- 1,850 people, healthy volunteers welcome
- Sponsor
- Cairo University
Contraception
A Comparison of Continuation Rates for Three Hormonal Contraceptive Methods
This study will assess the continuation rates among women using oral contraceptive pills, Depo-Provera and Ortho Evra following a first trimester abortion.
- Trial name
- NCT00253019
- Where
- United States
- Volunteers
- 321 people, healthy volunteers welcome
- Sponsor
- Emory University
Pain, Anxiety
The Use of Music for Pain and Anxiety Control During Abortion
Most first trimester abortions are performed under local anesthesia using either manual or electric vacuum suction aspiration. The majority of women undergoing these procedures experience some amount of pain and anxiety.
- Trial name
- NCT01013363
- Testing
- iPod Nano digital music player
- Where
- United States
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- Columbia University
Contraception
IUD Insertion Post First Trimester Abortion
The goal of this study is to provide better information about contraception to women having an abortion so that they are less likely to have another unintended unwanted pregnancy.
- Trial name
- NCT01174225
- Testing
- Flexi T 380(+) IUD, Nova T IUD
- Where
- Canada
- Volunteers
- 534 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Luteal Phase, Biomarkers
Early Pregnancy Cohort and Preimplantation Factor
Miscarriage is a common event associated with severe psychological and social morbidity, further tormenting in women suffering recurrent pregnancy loss (RPL) by at least three consecutive losses.
- Conditions
- Luteal Phase, Biomarkers, Abortion, Spontaneous, Abortion, Habitual
- Trial name
- PEP-cohort (NCT02761772)
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Nordsjaellands Hospital
Miscarriage, Missed Abortion
Letrozole Pretreatment With Misoprostol fInduction of Abortion In First-Trimester Missed Miscarriage
This study compares the success rate of letrozole and misoprostol versus misoprostol alone for medical termination of first trimester pregnancy.
- Trial name
- NCT03628625
- Testing
- Letrozole 2.5mg, Misoprostol
- Where
- Egypt
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Ain Shams Maternity Hospital
Threatened Miscarriage in First Trimester
Value of CA125 and Yolk Sac Morphology in Prediction of Pregnancy Outcome in Threatened Miscarriage
evaluation of serum CA125 level and yolk sac morphology in women with threatened miscarriage is very important to predict pregnancy outcome
- Trial name
- NCT03320213
- Volunteers
- 192 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
First Trimester Abortion
A Randomized Controlled Trial of Three Antibiotic Regimens for First Trimester Abortions
This study, a double blinded randomized controlled trial, is being done to compare side effects of commonly used antibiotic regimens prior to same day abortion procedures.
- Trial name
- NCT02756403
- Testing
- Azithromycin, Doxycycline, Metronidazole
- Where
- 2 sites in United States
- Volunteers
- 181 people, healthy volunteers welcome
- Sponsor
- Medstar Health Research Institute
First Trimester Abortion, Virtual Reality
Virtual Reality Experience in First Trimester D&C
Virtual reality (VR) has been used in health care settings to decrease anxiety and pain. This project is a feasibility study to evaluate whether virtual reality can be used in the setting of a first trimester pregnancy…
- Trial name
- NCT03533036
- Testing
- applied VR headset
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Abortion in First Trimester, Pain, Procedural
Ketamine Versus Fentanyl for Surgical Abortions
Ketamine is commonly used for procedural sedation and analgesia. It is widely used for trauma cases in the emergency department and is considered a superior agent in the outpatient setting due to its lack of respiratory and…
- Conditions
- Abortion in First Trimester, Pain, Procedural, Opioid Use
- Trial name
- NCT04871425
- Testing
- Ketamine, Fentanyl
- Where
- United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- University of Washington
Missed Abortion, Medical; Abortion, Fetus
Gemeprost Versus Dinoprostone in First Trimester Miscarriages
Comparison between gemeprost and dinoprostone to evacuate first trimester miscarriages.
- Conditions
- Missed Abortion, Medical; Abortion, Fetus, Incomplete Abortion
- Trial name
- NCT05342467
- Testing
- Gemeprost 1 Mg Vaginal Pessary, Dinoprostone 3 mg
- Where
- 2 sites in Malaysia
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- National University of Malaysia
Placenta; Implantation
The Accuracy of Ultrasound in the Detection of Placenta Site in the First Trimester.
The investigators speculate that ultrasound examination in the first trimester can accurately detect placental location. By performing both transabdominal ultrasound and later hysteroscopy on women with a first trimester missed…
- Trial name
- NCT04579796
- Testing
- ultrasound exam, hysteroscopy diagnostic
- Where
- Israel
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Assaf-Harofeh Medical Center
Abortion in First Trimester
Progesterone and Doppler in Recurrent Abortion
Recurrent pregnancy loss is classically defined as the occurrence of three or more consecutive pregnancy loss. The American Society of Reproductive Medicine has recently redefined recurrent pregnancy loss as two or more pregnancy…
- Trial name
- NCT03267771
- Testing
- Progesterone Suppositories Vaginal, Dydrogesterone Oral Tablet, doppler ultrasound
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Assiut University