Clinical trials: Abrasion
Periodontitis
Anti-infectious Therapy of Periodontitis - Comparison of Different Clinical Strategies
It is the aim of the study to evaluate the efficiency of "One stage full mouth disinfection" according to the original protocol (Quirynen et al.
- Trial name
- NCT03509233
- Testing
- Q-SRP, FMS, FMD
- Where
- 5 sites in Germany, Romania
- Volunteers
- 228 people
- Sponsor
- RWTH Aachen University
Dental Abrasion, Gingival Recession
Evaluation of Two Resin Composites and Two Adhesives for a Novel Restorative Protocol to Treat Cervical Lesions
Non-carious cervical lesion is frequently associated with gingival recession, resulting in a combined lesion that has a different treatment prognosis when the two lesions appear alone.
- Conditions
- Dental Abrasion, Gingival Recession, Composite Resins
- Trial name
- NCT03215615
- Testing
- Periodontal surgery, Total Etch adhesive, Universal Adhesive
- Where
- Brazil
- Volunteers
- 80 people
- Sponsor
- Universidade Estadual Paulista Júlio de Mesquita Filho
ELECTROENCEPHALOGRAPHIC VARIANT PATTERN 1 (Disorder)
Self Abrading Rapidly Applied Electrode Validation
The SARA (Self Abrading Rapidly Applied) electrode will speed EEG patient hookup by combining multiple steps that burden conventional EEG procedures into one.
- Trial name
- SARA (NCT02200523)
- Testing
- SARA electrode, Gold cup
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Cleveland Medical Devices Inc
Corneal Abrasions, Corneal Infiltrates
High-resolution Imaging of Corneal Lesions With Optical Coherence Tomography (OCT) - A Pilot Study
Corneal lesions such as corneal abrasions and corneal infiltrates are common in clinical practice. The current study seeks to investigate whether high-resolution OCT is suitable for imaging of these corneal lesions.
- Trial name
- NCT01753583
- Testing
- Optical Coherence Tomography (OCT), Slit lamp biomicroscopy
- Where
- Austria
- Volunteers
- 4 people
- Sponsor
- Medical University of Vienna
Gingival Recession, Tooth Abrasion
A New Surgical-restorative Approach to Treat Gingival Recessions Associated With Non-carious Cervical Lesions (NCCL)
The aim of the present study is to evaluate the clinical, aesthetic and patient-centered parameters of connective tissue graft associated or not with partial resin composite (RC) for the treatment of gingival recession with NCCL…
- Trial name
- NCT02817763
- Testing
- Connective tissue graft (CTG), CTG plus resin composite restoration, sodium dipyrone
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Universidade Estadual Paulista Júlio de Mesquita Filho
Periodontal Diseases
Impact of Full Mouth Erythritol Powder Air Polishing on Systemic Inflammatory Response
Periodontitis (PD) is an inflammatory condition that affects 20%-50% of the total global population, with severe disease occurring in 9.8% of individuals.
- Trial name
- NCT05812391
- Testing
- test, conventional
- Where
- Iraq
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- University of Baghdad
Malignant Pleural Effusion, Thoracic Cancer
Video Assisted Thoracoscopic Surgery (VATS) - Surgical Pleurodesis vs Tube Drainage in Management of Malignant Pleural Effusion (MPE)
Malignant Pleural Effusion (MPE) is considered to be a common presentation at malignant tumors representing 15% of all cancer cases. It carries a burden on our patients with dyspnea being the most common symptom in most of cases.
- Trial name
- NCT05872126
- Testing
- VATS-Surgical pleurodesis, Tube Drainage
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Assiut University
Gingival Recession, Localized
Effect of Restoration Margin Level in the Treatment of Gingival Recession Associated With Non-carious Cervical Lesion
The aim of this randomized, parallel-group clinical trial was to compare the 1-year periodontal, root coverage, esthetic, and patient-centered outcomes of the partial restoration placement with different apical margin levels…
- Trial name
- NCT05682274
- Testing
- Partial restoration approach combined with CAF+CTG
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Gazi University
Epidermolysis Bullosa Dystrophica, Epidermolysis Bullosa Dystrophica, Recessive
A Natural History Study of Corneal Abrasions in Patients With Dystrophic Epidermolysis Bullosa (DEB)
This study is a non-interventional, observational study that will evaluate the natural history of corneal abrasions in patients with Dystrophic Epidermolysis Bullosa (DEB).
- Conditions
- Epidermolysis Bullosa Dystrophica, Epidermolysis Bullosa Dystrophica, Recessive, Epidermolysis Bullosa Dystrophica Dominans
- Trial name
- NCT06563414
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Krystal Biotech, Inc.
Tooth Abrasion
Enamel Abrasion and Stain Removal Efficacy of Two Whitening Toothpastes: An In-vitro and In-vivo Trial
The aim of the study is to clinically evaluate the efficacy of external stain removal of an activated charcoal based tooth paste versus calcium carbonate /perlite tooth paste.
- Trial name
- NCT05650840
- Testing
- Charcoal based whitening toothpaste (signal charcoal white& Detox toothpaste Unilever Mashreq - Egypt, Calcium carbonate /perlite containing whitening toothpaste (signal whitening moonlight toothpaste Unilever Mashreq - Egypt).
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Cairo University
Chondral Defect, Osteochondral Defect
EB-OC for the Treatment of Focal Chondral/Osteochondral Defects in the Knee
EB-OC is a tissue engineered osteochondral tissue graft comprising of a living tissue engineered cartilage layer attaching to a bone scaffold.
- Trial name
- NCT06895889
- Testing
- EB-OC Graft Implantation, Abrasion chondroplasty
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Epibone, Inc.
Fluorosis, Dental, Enamel Discoloration
The Effectiveness of Antivet Versus Opalustre® for the Management of Enamel Fluorosis/Discolored Enamel and Its Impact on Aesthetic Outcomes.
Dental fluorosis is a developmental enamel defect characterized by discoloration and altered enamel appearance, which may negatively affect dental esthetics and patient satisfaction.
- Trial name
- NCT07707349
- Testing
- Antivet, Opalusture
- Where
- Egypt
- Volunteers
- 59 people
- Sponsor
- October University for Modern Sciences and Arts
Abrasion, Discoloration, Tooth
Enamel Abrasion and Stain Removal Efficacy
Enamel abrasion and stain removal efficacy of two whitening toothpastes
- Trial name
- NCT05619315
- Testing
- Charcoal -based whitening toothpaste, Calcium carbonate /perlite containing whitening toothpaste.
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Cairo University
Malignant Pleural Effusion
Pleural Bleomycin vs Mechanical Abrasion in Malignant Pleural Effusion
Comparision between pleurodesis by pleural abrasion using medical thoracoscopy and bleomycin instillation via indwelling pleural catheter.
- Trial name
- NCT06691009
- Testing
- Group 1 (mechanical pleurodesis), Group 2 chemical pleurodesis by bleomycin)
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Assiut University
Gingival Recession, Gingival Abrasion
Evaluation of Gingival Fissures Associated With Soft and Medium Toothbrushes
Gingival fissures (GF) have been suggested as risk indicators for clinical attachment loss (CAL) and gingival recession, especially in free surfaces and in patients with low plaque scores.
- Conditions
- Gingival Recession, Gingival Abrasion, Wounds and Injuries
- Trial name
- NCT03367481
- Testing
- Toothbrush type
- Where
- Brazil
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Federal University of Rio Grande do Sul
Gingival Recession, Tooth Abrasion
Mucoderm® Versus CTG in the Treatment of Multiple Gingival Recessions Associated With Non-carious Cervical Lesion.
The aim of the present study is to compare two different multidisciplinary protocols using two types of grafts, porcine acellular dermal matrix (Mucoderm®) versus connective tissue graft, both associated with modified coronally…
- Trial name
- NCT03594513
- Testing
- MCAF, PR, CTG
- Where
- Brazil
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Universidade Estadual Paulista Júlio de Mesquita Filho
Pneumothorax
Pleurectomy Versus Pleural Abrasion in Patients With Spontaneous Pneumothorax
Pneumothorax refers to air in the pleural cavity (i.e. interspersed between the lung and the chest wall).1 Primary spontaneous pneumothorax (PSP) mostly occurs in healthy individuals without an apparent cause, probably due to the…
- Trial name
- NCT05407974
- Testing
- pleurectomy
- Where
- Egypt
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Hyperkalaemia
Study of SZC and Enhanced Nutrition Advice Compared to SoC in Dialysis Patients With Hyperkalaemia
Prescribing Sodium zirconium cyclosilicate (SZC) with enhanced nutritional advice to participants with hyperkalaemia on haemodialysis will reduce serum K+ (S-K+ ) and enable the consumption of more fruit and vegetables and more…
- Trial name
- GRAZE (NCT04997161)
- Testing
- Sodium Zirconium Cyclosilicate (SZC), Enhanced dietary advice, Standard dietary advice including K+ restriction.
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- AstraZeneca
Gingival Abrasion
Assessment of a Sonic Toothbrush on the Abrasion of the Gingival Tissue
This is a randomized, monocentric, examiner-blind, two-arm, parallel, controlled clinical research study. It aims to assess gingival abrasion by the comparison of pre- to- post-brushing after a single brushing and after 12 weeks…
- Trial name
- ASTA (NCT05375227)
- Testing
- Teeth brushing
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Philips France Commercial
Primary and Secondary Spontaneous Pneumothorax
Does Non-Steroidal Anti-inflammatory Drugs Decrease the Quality of Pleurodesis After Mechanical Pleural Abrasion/Pleurectomy for Treatment of Pneumothorax?
Investigators aim to assess if NSAIDs affect the quality of pleurodesis resulting from mechanical pleurodesis (open surgery or VATS) regarding : Primary outcome: Recurrence of pneumothorax in 6 monthes.
- Trial name
- NCT06467318
- Testing
- Paracetamol, NSAID, Paracetamol
- Where
- Egypt
- Volunteers
- 116 people, healthy volunteers welcome
- Sponsor
- Ain Shams University