Clinical trials: Abscess
Fournier Gangrene, Perianal Abscess
The Immunological Differences Between Fournier Gangrene and Perianal Abscess
Although it is rarely observed, necrotizing fasciitis progresses with high mortality and serious complications. Fournier's gangrene is a specific form of necrotizing fasciitis.
- Trial name
- NCT05529628
- Testing
- Cytokine levels
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Istanbul Training and Research Hospital
Abscess
Emergency Bedside Ultrasound for Pediatric Soft Tissue Infections
The purpose of this study is to determine if soft tissue infections in pediatric patients can be more accurately diagnosed (i.e.
- Trial name
- NCT00595881
- Testing
- Bedside emergency ultrasound
- Where
- United States
- Volunteers
- 420 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Philadelphia
Dental Pulp Necrosis, Periapical Abscess
Efficiency of Triple Antibiotic Paste, Ciprofloxacin/Propolis, Ciprofloxacin/Metronidazole, Propolis/Metronidazole Combinations on Revascularization Process of Immature Necrotic Maxillary Incisors of Patients 8-18 Years Old.
This Study Was Made to Evaluate the Antibacterial Effect of Different Antibacterial Combinations on Revascularization Process in Permanent Anterior Immature Teeth.
- Conditions
- Dental Pulp Necrosis, Periapical Abscess, Root Canal Infection
- Trial name
- NCT03533231
- Testing
- Canal Disinfection Triple Antibiotic Paste (TAP), Ciprofloxacin + Propolis Paste, Ciprofloxacin + Metronidazole Paste
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Tariq Yehia
Hidradenitis Suppurativa
Study of the Immunomodulation in the Hidradenitis Suppurativa and Evaluation of a New Therapeutic Strategy
Hidradenitis suppurativa (HS), also known as Verneuil's disease, is a chronic inflammatory dermatosis of the hair follicule located mainly in the skin folds (axillae, inguinal, submammary, etc.).
- Trial name
- IMOHS (NCT05208099)
- Testing
- Blood tests, exeresis, abdominoplasty
- Where
- 2 sites in France
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Lille Catholic University
Abdominal Abscess
Antibiotic Irrigations for Intra-Abdominal Drains
Intra-abdominal abscesses are pus-filled pouches in the abdominal cavity. Current standard of care includes drain placement in the abscess cavity to reach source control as well as administration of systemic antibiotics.
- Trial name
- AID (NCT03476941)
- Testing
- Gentamicin Sulfate Inj 20mg/2ml vial for injection, Clindamycin phosphate 6 mg/1ml for injection
- Where
- United States
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- University of Iowa
Cellulitis, Wound Infection
Penicillin for the Emergency Department Outpatient Treatment of CELLulitis
The main objective of this study is to investigate the non-inferiority of oral flucloxacillin alone compared with a combination of oral flucloxacillin and phenoxymethylpenicillin for the emergency department directed outpatient…
- Conditions
- Cellulitis, Wound Infection, Abscess
- Trial name
- PEDOCELL (NCT02922686)
- Testing
- Flucloxacillin, Phenoxymethylpenicillin
- Where
- 5 sites in Ireland
- Volunteers
- 414 people, healthy volunteers welcome
- Sponsor
- Royal College of Surgeons, Ireland
Aseptic Abscess Syndrome
Role of Gut Microbiota in the Pathophysiology of Aseptic Abscesses
Aseptic abscess syndrome (AA) is a rare entity characterized by the occurrence of deep abscesses with no germ found. Antibiotic therapy is ineffective and they are sensitive to anti-inflammatory treatment with corticosteroids.
- Trial name
- ABSCESSBIOT (NCT05537909)
- Testing
- Biological sample collection
- Where
- 15 sites in France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand
Skin Disease, Bacterial, Abscess
Evaluation of 3 Versus 10 Days of Antibiotics in Skin Abscesses After Surgical Drainage
The objective of this study is to determine if there is a difference in treatment failures and recurrent skin infections when patients are given 3 or 10 days of antibiotics for uncomplicated skin abscesses after they have been…
- Trial name
- NCT02024867
- Testing
- Trimethoprim-Sulfamethoxazole
- Where
- United States
- Volunteers
- 249 people, healthy volunteers welcome
- Sponsor
- Lucy Holmes, MD
Community-Acquired MRSA Infections, Abscesses
An Attempt to Reduce Community-Acquired Methicillin-Resistant Staphylococcus Aureus (MRSA) Infection in Soldiers
The main purpose of this study is to determine if applying mupirocin into soldiers noses who are colonized with methicillin-resistant Staphylococcus aureus (MRSA) will reduce infections in them and their cohort of fellow soldiers.
- Conditions
- Community-Acquired MRSA Infections, Abscesses, Cellulitis, Folliculitis
- Trial name
- NCT00289588
- Testing
- Mupirocin (drug)
- Where
- United States
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Brooke Army Medical Center
Bartholin´s Cyst
The Treatment of Bartholin´s Cyst or Abscess With Silver Nitrate
Silver nitrate treatment of Bartholin's cyst or abscess will be compared to marsupialization treatment. It is expected that silver nitrate treatment is effective, simple, inexpensive and the least anaesthetic requiring procedure…
- Trial name
- NCT00786461
- Testing
- silver nitrate application to the Bartholin´s cyst, silver nitrat stick
- Where
- Denmark
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Periappendicular Abscess
The Treatment of Periappendicular Abscess After the Acute Phase
The PeriAPPAC trial is a prospective randomised study comparing interval laparoscopic appendectomy with follow-up MRI in patients with initially successfully treated periappendicular abscess.
- Trial name
- PeriAPPAC (NCT03013686)
- Testing
- Interval appendectomy, Follow-up with MRI
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Turku University Hospital
Abscess
Antibiotics Versus Placebo in the Treatment of Abscesses in the Emergency Department
The purpose of this study is to determine if there is a difference between an antibiotic, trimethoprim-sulfamethoxazole versus placebo in healing outcomes of soft tissue abscesses following incision and drainage.
- Trial name
- NCT00867789
- Testing
- Trimethoprim-sulfamethoxazole, Sugar pill
- Where
- United States
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Children's Mercy Hospital Kansas City
Infection, Mediastinitis
Prognostic Factors for Descending Necrotizing Mediastinitis Development in Deep Space Neck Infections
Descending necrotizing mediastinitis (DNM) is the most serious complication of deep neck infections (DNI) with high mortality. The objective of this retrospective study was to evaluate possible prognostic factors for DNM…
- Conditions
- Infection, Mediastinitis, Neck Abscess, Inflammation
- Trial name
- NCT04865003
- Testing
- treatment of infection
- Volunteers
- 289 people, healthy volunteers welcome
- Sponsor
- Clinical Center of Vojvodina
Lateral Sinus Thrombosis, Mastoiditis
Otogenic CSVT Retrospective Case Series and Associated Thrombophilia
The aim of this study is to report the clinical presentation, Microbiological, laboratory and imaging evaluation, prothrombotic factors analysis, medical and surgical management and outcomes in children with Otogenic Cerebral…
- Conditions
- Lateral Sinus Thrombosis, Mastoiditis, Otitis Media
- Trial name
- CSVT PCR (NCT03864055)
- Where
- Israel
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- HaEmek Medical Center, Israel
Abscesses
Prospective Randomized Trial of Bactrim on 7 Day Outcome in Patients With Uncomplicated Abscesses
Patients will be enrolled in a multi-center study to prospectively evaluate outcome after treatment for an uncomplicated skin abscess. All patients will receive incision and drainage and wound cultures.
- Trial name
- NCT00973765
- Testing
- bactrim
- Where
- United States
- Volunteers
- 212 people, healthy volunteers welcome
- Sponsor
- 59th Medical Wing
Appendix Abscess, Appendicitis
The Prevalence of Appendiceal Tumours in Periappendicular Abscess
Complicated and uncomplicated appendicitis follow different epidemiological trends also suggesting different pathophysiology behind these two different forms of appendicitis.
- Conditions
- Appendix Abscess, Appendicitis, Appendix Mass, Appendix Cancer
- Trial name
- PeriAPPAC-T (NCT04634448)
- Testing
- Interval appendectomy, Follow-up MRI at 1 year
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Turku University Hospital
Dentoalveolar Abscess
C-reactive Protein Levels in Acute Apical Abscess Due to Root Canal Infection
C-reactive protein levels of patients with acute apical abscess are evaluated before and after root canal treatment
- Trial name
- NCT04684407
- Testing
- ROOT CANAL TREATMENT
- Where
- India
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- CSI College of Dental Sciences and Research, Madurai
Chronic Apical Periodontitis, Necrosis of Pulp
Using Platelet-rich Fibrin in Regenerative Endodontic Treatment in Mature Permanent Teeth
This study aims to evaluate the antibacterial effects of injectable platelet-rich fibrin (i-PRF) in vitro, and to assess the clinical and radiographic outcomes of using advanced platelet-rich fibrin (A-PRF+) and i-PRF in…
- Conditions
- Chronic Apical Periodontitis, Necrosis of Pulp, Acute Apical Periodontitis of Pulpal Origin, Periapical Abscess
- Trial name
- NCT07192289
- Testing
- Using advanced platelet-rich fibrin (A-PRF+) or injectable platelet-rich fibrin (i-PRF) in regenerative endodontic treatment in mature permanent teeth.
- Where
- Vietnam
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- University of Medicine and Pharmacy at Ho Chi Minh City
Peritonsillar Abscess
Ultrasound-Guided Aspiration of PTA vs Conventional Landmark Technique - a RCT
The study is a prospective randomized controlled trial conducted at two different centers at the Department of ORL - Head \& Neck Surgery, Odense University Hospital and the Department of Otorhinolaryngology, Head and Neck…
- Trial name
- NCT03824288
- Testing
- Intraoral ultrasound, The landmark technique
- Where
- 2 sites in Denmark
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Tobias Todsen
Lacerations, Abscess
Effectiveness of Nitrous Oxide in the ED
This will be a randomized control trial. All patients for whom an emergency provider determines that abscess drainage or laceration repair are necessary will be considered for enrollment.
- Trial name
- NCT02703233
- Testing
- Nitrous Oxide, Oxygen
- Volunteers
- healthy volunteers welcome
- Sponsor
- Christiana Care Health Services