Clinical trials: Absence, active
Atrial Fibrillation, Left Atrial Appendage Absent
Can Patients With Atrial Fibrillation Safely Discontinue Anticoagulant Therapy After Cardiac Surgery? (ATLAAC)
Left atrial appendage (LAA) closure has become a frequent addition to oral anticoagulation in patients with atrial fibrillation who undergo cardiac surgery.
- Conditions
- Atrial Fibrillation, Left Atrial Appendage Absent, Anticoagulant Adverse Reaction
- Trial name
- NCT06401616
- Testing
- OAC will be discontinued for the duration of the trial
- Where
- 6 sites in Denmark
- Volunteers
- 1,220 people
- Sponsor
- Odense University Hospital
Rare Disorders, Undiagnosed Disorders
Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford
The Coordination of Rare Diseases at Sanford (CoRDS) is an international patient registry that serves as a centralized resource for rare disease research.
- Conditions
- Rare Disorders, Undiagnosed Disorders, Disorders of Unknown Prevalence, Cornelia De Lange Syndrome
- Trial name
- CoRDS (NCT01793168)
- Where
- United States
- Volunteers
- 20,000 people
- Sponsor
- Sanford Health
Dehiscence, Tooth Extraction
Effect of Collagen Membrane on Ridge Preservation
This study will evaluate whether adding a resorbable collagen membrane to an anorganic bone-collagen composite (ABCC) graft improves ridge preservation after tooth extraction.
- Conditions
- Dehiscence, Tooth Extraction, Alveolar Bone Loss
- Trial name
- NCT07580495
- Testing
- Minimally Invasive tooth extraction, Alveolar ridge preservation with ABCC, Resorbable collagen membrane (InterCollagen® Guide)
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Debora Dias
Night Shift Work, Sickness Absence
Night Work Hours Reduction Trial
The primary aim of this study is to investigate the effects of reducing weekly working hours among employees working night shifts regularly from 38 hours 15 minutes to 36 hours on payroll-based, objective working-hour…
- Trial name
- WHRedu (NCT07848607)
- Testing
- Reduced Working Hours (from 38h15minutes to 36h)
- Where
- 3 sites in Finland
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Finnish Institute of Occupational Health
Musculoskeletal Pain, Mental Health Wellness 1
Health in Work - a Measure for Increased Coping and Work Inclusion
Health in work - a measure for increased coping and work participation -An effect analysis of a health- and work environment intervention at the workplace.
- Conditions
- Musculoskeletal Pain, Mental Health Wellness 1, Work-Related Condition
- Trial name
- HiAforsk (NCT04000035)
- Testing
- Health and work environment information and processes
- Where
- Norway
- Volunteers
- 1,383 people, healthy volunteers welcome
- Sponsor
- University Hospital of North Norway
Autism Spectrum Disorder, Autism Spectrum Disorder (ASD)
Intranasal Insulin for Autism Spectrum Disorder in Children and Young Adults Aged 4 to 21 Years
This observational study evaluates the real-world use of intranasal insulin in children and young adults with autism spectrum disorder (ASD) utilizing the ViaNase™ device developed by Kurve Therapeutics.
- Conditions
- Autism Spectrum Disorder, Autism Spectrum Disorder (ASD), Autism Spectrum Disorder High-Functioning, Autism Spectrum Disorder With Absence of Functional Language
- Trial name
- IN-INS-AUT (NCT07521371)
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Healing Hope International
Osteogenesis Imperfecta, Total Absence of Permanent Teeth
Site Preservation After Tooth Extraction
This study is mainly targeted affected teeth which could not be retained, and patients are willing to undergo implant repair at the later stage.
- Conditions
- Osteogenesis Imperfecta, Total Absence of Permanent Teeth, Tooth Socket
- Trial name
- NCT05258019
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Nanfang Hospital, Southern Medical University
Acute Kidney Injury
A Study to Evaluate the Safety and Feasibility of Continuous Renal Replacement Therapy With Regional Citrate Anticoagulation in a Cohort Critical Ill Patients With Acute Kidney Injury and Presumed Absent Citrate Metabolism
Use of regional citrate anticoagulation in an at risk population with decreased citrate metabolism. This study assesses the feasibility and safety of regional citrate anticoagulation in this population.
- Trial name
- CAT-RISK (NCT07751874)
- Testing
- continuous renal replacement therapy with regional citrate anticoagulation
- Where
- Belgium
- Volunteers
- 50 people
- Sponsor
- University Hospital, Antwerp
Tooth Absence
Comparison of Osseodensification and Conventional Drilling on the Stability of Tapered and Cylindrical Implants.
The effect of osseodensification versus conventional implant site preparation on implant stability for tapered and cylindrical dental implants.
- Trial name
- NCT07244185
- Testing
- Dental Implant Placement with Osseodensification or Conventional Drilling
- Where
- Iraq
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Worood Adnan Akram
Oxygen Supply Absent
Monitoring Free Tissue Transfer Hemodynamics Using NIRS
Free tissue transfer (FTT) is a surgical procedure for repairing cancer resection wounds. Free tissue transfer usually involves taking skin from one area of the body (e.g.
- Trial name
- NCT06661525
- Testing
- Free Flap NIRS
- Where
- 2 sites in Canada
- Volunteers
- 60 people
- Sponsor
- University of British Columbia
Asenteeism
Classroom Air Purifiers for Reducing School Absence
Background Respiratory infections like influenza and SARS-CoV-2 pose significant global health risks due to their high transmissibility and severity.
- Trial name
- NCT07119333
- Testing
- Air purifiers
- Where
- Norway
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Norwegian Institute of Public Health
Chest Pain, Ischemia
Evaluation of Patients With Non-obstructive Coronary Arteries
Patients with angina and non-obstructive CAD are common within clinical practice, but remain a challenge with regard to diagnosis and treatment.
- Trial name
- noCAD (NCT00823563)
- Testing
- 30 cc blood draw, Intravascular ultrasound (IVUS), Coronary pressure/flow wire testing
- Where
- United States
- Volunteers
- 2,000 people
- Sponsor
- Stanford University
HIV I Infection, Injection Pain
Impact of Pain From Injectables Antiretroviral Treatments in HIV-1 Patients Based on the Injection Site (Ventrogluteal or Dorsogluteal) and the Use or Non-use of Virtual Reality Headset
This is a multicenter, randomized, open-label study with a cross-over design. The objective of this project is to compare the intensity of pain induced by injectable antiretroviral (ARV) treatment (Cabotegravir® and Rilpivirine®)…
- Trial name
- VIHINJECT (NCT06834113)
- Testing
- Dorsogluteal intramuscular injection
- Where
- 5 sites in France
- Volunteers
- 120 people
- Sponsor
- Centre Hospitalier Régional d'Orléans
Lung Cancer (Diagnosis)
Robotic Bronchoscopy for Small Lung Nodules Without a Bronchus Sign
The goal of this observational study is to learn about the diagnostic performance and safety of robotic-assisted bronchoscopy using the Ion Endoluminal System in adults with small lung nodules that do not show a bronchus sign on…
- Trial name
- NCT07862816
- Where
- 4 sites in South Korea
- Volunteers
- 151 people
- Sponsor
- Intuitive Surgical
SLAP Lesion
Biceps Tenodesis With 360 Suture Anchor Versus Self Locking Tenodesis In the Absence of Rotator Cuff Tears
This is a prospective randomized controlled trial. The aim of this study is to compare the clinical results and complications of self-locking biceps tenodesis and double-loop 360 lasso biceps tenodesis for the treatment of…
- Trial name
- Blast2 (NCT06772103)
- Testing
- self-locking biceps tenodesis, Biceps Tenodesis with 360 Suture anchor
- Where
- France
- Volunteers
- 98 people
- Sponsor
- Clinique Générale dAnnecy
Heart Failure, Cognitive Impairment
TRAnscranial Doppler CErebral Blood Flow and Cognitive IMPAIRment in Heart Failure
TRACE-IMPAIR is a prospective, clinical study of consecutive patients that evaluates the relationship between heart failure (HF) and cognitive impairment in relation to carotid and cerebral flow.
- Conditions
- Heart Failure, Cognitive Impairment, Carotid Stenosis
- Trial name
- TRACE-IMPAIR (NCT05250349)
- Testing
- Echocardiography, Doppler sonography, Neuropsychological tests
- Where
- Poland
- Volunteers
- 300 people
- Sponsor
- John Paul II Hospital, Krakow
Absent Pulmonary Artery
A Study Of Surgical Repair Of Discontinuous Branching Pulmonary Arteries
The purpose of this study is to test the safety and performance of a new blood vessel graft, called the ATEV. The graft is designed to reconnect the heart to the lungs and to grow as the child grows, which may eliminate the need…
- Trial name
- NCT07785661
- Testing
- Acellular Tissue Engineered Vessel (ATEV) Conduit
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Joseph Dearani
Pseudo Obstruction
ACTG2/FLNA Testing Yield in Adult Idiopathic Chronic Intestinal Pseudo-Obstruction (CIPO) With Reduced/Absent Distal Esophageal Contractility
To assess the diagnostic yield of Sanger sequencing for ACTG2 and FLNA genes evaluation on blood or saliva sample in patients with idiopathic CIPO in which high-resolution esophageal manometry (HRM) shows reduced (DCI <450…
- Trial name
- CIPO_GEN (NCT07448753)
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- Marina Coletta
Hypertension, Hypertension,Essential
Renal Artery Denervation Assessment Without Antihypertensive Medication Regimen (RADAR)
To obtain an assessment of the efficacy and safety of renal denervation by dehydrated alcohol injection, USP administered via the Peregrine System™ Infusion Catheter in hypertensive subjects in the absence of antihypertensive…
- Trial name
- RADAR (NCT07083765)
- Testing
- Dehydrated Alcohol Injection, USP
- Where
- United States
- Volunteers
- 202 people
- Sponsor
- Ablative Solutions, Inc.
Heart Failure With Reduced Ejection Fraction (HFrEF)
Correlation of Typical LBBB Mechanical Activation Pattern by 2D Strain Echocardiography With Acute GWE Improvement in Patients Receiving LBBp or Conventional BiVp for Cardiac Resynchronization Therapy (Echo LBBp)
The present study is a multicenter interventional non randomised study in patients requiring an implantable device for cardiac resynchronization therapy.
- Trial name
- ECHO-LBBp (NCT06689111)
- Testing
- Left bundle branch pacing lead, CRT with the standard method through cs
- Where
- Greece
- Volunteers
- 100 people
- Sponsor
- University Hospital of Patras