Clinical trials: Absorption; Iron
Iron Deficiency
Mineral Absorption From Fortified Rice Produced With Different Fortification Techniques
The investigators studies will compare iron, respectively iron and zinc bioavailability from fortified rice produced from different fortification techniques using stable isotopic labels.
- Trial name
- NCT02572128
- Testing
- Fortified rice
- Where
- 2 sites in Switzerland
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
Infant, Dietary Supplements
Iron Absorption From Infant Formula and Iron Drops in Infants (MJAU-studien)
Iron deficiency (ID) affects up to 25% of Swedish infants and severe ID is associated with cognitive and behavioral problems. To avoid this, iron supplements or iron-fortified infant foods are recommended for infants.
- Conditions
- Infant, Dietary Supplements, Food, Fortified
- Trial name
- MJAU (NCT01216709)
- Testing
- ferrous sulfate, iron-fortified infant formula (12.4 mg iron/L), iron-fortified infant formula (2.3 mg iron/L)
- Where
- Sweden
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Umeå University
Iron-deficiency Anemia
IHAT Absorption Kinetics
At MRC Human Nutrition Research, the investigators have developed an engineered analogue of the ferritin-core for safe and effective iron supplementation.
- Trial name
- NCT02498886
- Testing
- IHAT, Ferrous sulphate
- Where
- The Gambia
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Medical Research Council
Iron Deficiencies
Iron Absorption From Naturally Dephytinized Legumes
Consumption of less meat and more plant-based protein can greatly reduce the negative impact of food production on the environment. Studies show that vegan diets can decrease greenhouse gas emissions, land use, and water.
- Trial name
- LINDA (NCT06032832)
- Testing
- soy protein concentrate-meat analog, soy protein concentrate-meat analog_dephytinization, pork meat
- Where
- Switzerland
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Diego Moretti
Anemia, Iron Deficiency
Effect of Timing of Micronutrient Powder Consumption on Iron Absorption in Infants
Infants and young children in sub-Saharan Africa have high rates of iron deficiency anemia (IDA), which adversely affects their growth and cognitive development.
- Trial name
- NCT02989311
- Testing
- Fortified maize porridge (MNP and Iron), Fortified Maize porridge (MNP + Iron + GOS)
- Where
- Kenya
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
Iron-deficiency
Effect of Polyphenols on Absorption of Iron From Sodium Iron Chlorophyllin
Polyphenols present in tea are known to inhibit the absorption of non heme iron. The inhibiting effect of tea on non-heme iron absorption is attributed to the flavonoids present in tea.
- Trial name
- polySIC (NCT04849832)
- Testing
- SIC, SIC + tea, FeSO4
- Where
- Switzerland
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
Iron Absorption
Dietary Iron Requirements
Dietary Reference Intakes (DRIs) for iron are based on a relatively small number of studies in European populations. This research study will determine iron needs in a representative sample of adults living in the US using the…
- Trial name
- NCT07139821
- Testing
- Stable iron isotope
- Where
- 2 sites in United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Pennington Biomedical Research Center
Iron-deficiency
Effect of Prebiotics on Iron Absorption in Women With Low Iron Stores
Rationale: According to the WHO, iron deficiency is still the most common and widespread nutritional disorder in the world. Current iron supplements have limitations in terms of bioavailability and tolerability.
- Trial name
- Fe_GOS_1 (NCT03325270)
- Testing
- labeled ferrous fumarate, labeled ferrous fumarate + prebiotics, labeled ferrous sulfate + prebiotics
- Where
- Switzerland
- Volunteers
- 46 people
- Sponsor
- Swiss Federal Institute of Technology
Enrichment of Blood
Iron Absorption From Biofortified Beans With Different Levels of Phytic Acid
Iron deficiency and iron deficiency anemia are among the major health problems in the developing world. Women of childbearing age as well as children are the most vulnerable population groups.
- Trial name
- NCT01521273
- Testing
- Bean varieties
- Where
- Rwanda
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
Iron Deficiency
Malaria and the Safety of Iron Supplements and Iron Fortification
The primary study hypothesis of the investigators is that administration of an iron supplement between meals at a dose like that used in the Pemba trial (~1 mg Fe/kg) during P.
- Trial name
- MIA (NCT01156896)
- Testing
- Ferrous sulfate
- Where
- Thailand
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Columbia University
Iron Deficiency, Anemia
Iron Absorption From Rice Fortified With Ferric Pyrophosphate
Ferric pyrophosphate (FePP) is a water-insoluble, food grade iron compound used to fortify rice, infant cereals and chocolate-drink powders as it causes no organoleptic changes to the food vehicle.
- Conditions
- Iron Deficiency, Anemia, Iron Deficiency Anemia
- Trial name
- NCT02176759
- Testing
- Administration of rice fortified with regular FePP, Administration of rice fortified with regular FePP with citrate added during extrusion, Administration of rice fortified with regular FePP and citrate added at consumption
- Where
- Switzerland
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
Iron Deficiency, Anemia
The Efficacy of a Local Vitamin-C Rich Fruit (Guava) in Improving Iron Absorption From Mungbean Based Meals and Its Effect on Iron Status of Rural Indian Children (6-10 Years)
Iron deficiency is estimated to affect about one fifth of the world's population, and women and children are among the most severely affected.
- Trial name
- MUGUST_2 (NCT01191463)
- Testing
- Mung Bean Meal, Guava
- Where
- India
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Wageningen University
Iron Absorption
Effects of Vitamin A and Carotenoids on Iron Absorption
The objective of this study is to investigate the effect of vitamin A and carotenoids on iron absorption in healthy subjects with low and normal vitamin A status.
- Trial name
- NCT01493297
- Testing
- Labeled iron solutions
- Where
- Venezuela
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
Iron Deficiency
Absorption of Heme and Non-Heme Iron in Pregnant and Non-pregnant Women and Mechanisms of Fetal Iron Transfer
The three specific aims of this study are 1) to assess the impact of iron status on relative differences in absorption of heme and non-heme iron among pregnant women and non-pregnant women, 2) to assess the magnitude and the…
- Trial name
- NCT01019096
- Where
- 2 sites in United States
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Cornell University
Micronutrient Deficiencies
Effect of Sprinkles With and w/o Fe on Zn Absorption in Kenyan Toddlers
The investigators propose to study the effects of increased iron intake by home fortification of complementary foods on the gastrointestinal microbial development, inflammatory responses, and zinc (Zn) absorption.
- Trial name
- NCT02101723
- Testing
- MNP + Zn/Fe, MNP + Zn
- Where
- 2 sites in United States, Kenya
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Iron Deficiency, Anemia
The Optimization of Bioavailability From Iron Supplements: Study 2
Iron deficiency (ID) with or without anaemia (IDA) is a major public health problem worldwide, especially in women of reproductive age and young children.
- Conditions
- Iron Deficiency, Anemia, Iron Deficiency Anemia
- Trial name
- NCT02177851
- Testing
- Single oral iron dose of 120 mg per day for 3 consecutive days, Two oral iron doses of 60 mg per day (morning + afternoon) for 3 consecutive days
- Where
- Switzerland
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
Blood Iron Isotope Enrichment
Impact of Bean Polyphenols and Phytic Acid on Iron Absorption
Recently isolated low PA varieties (lpa) in wheat, rice, maize, barley and beans might have the potential to alleviate iron bioavailability problems associated with PA.
- Trial name
- NCT01472484
- Testing
- 586/8x87 white, 586/8x87 brown, BAT 881
- Where
- Switzerland
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
Iron Deficiency
Iron Absorption From Tef-injera in Women of Reproductive Age
Anemia is one of the most common health problems all over the world with around half of preschool-aged children (<5 years) and one third of women affected.
- Trial name
- NCT01687062
- Testing
- FeSO4, reduction of phytate, NaFeEDTA
- Where
- Switzerland
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
Malaria, Falciparum
Study of Iron Absorption and Utilization in Asymptomatic Malaria
Anemia is still a main public health problem in sub-Saharan Africa. Anemic women have an increased maternal and perinatal mortality and anemic adults have diminished work capacity.
- Trial name
- NCT01108939
- Testing
- Antimalarial treatment, Observation
- Where
- Benin
- Volunteers
- 23 people
- Sponsor
- Swiss Federal Institute of Technology
Iron Requirements, Pregnancy
Iron Absorption and Requirements in Pregnancy and Lactation
Iron requirements increase significantly during pregnancy. Current recommendations for iron intake in pregnant and lactating women (PLW) are mainly based on factorial estimates and extrapolated from non-PLW.
- Conditions
- Iron Requirements, Pregnancy, Lactation, Infancy
- Trial name
- PILLAR_II (NCT05973552)
- Testing
- CO-rebreathing, Oral iron isotope administration (54Fe), Intravenous iron isotope administration (58Fe)
- Where
- Kenya
- Volunteers
- 250 people
- Sponsor
- University of Oxford