Clinical trials: Absorption, open to volunteers
Iron Deficiency (Without Anemia)
Absorption of Iron From Stabilized Lactoferrin: A Study in Women With Iron Deficiency
Lactoferrin (LF) is a natural iron-binding protein found in milk. It exists either in an iron-free state (apo-LF) or bound to iron (holo-LF).
- Trial name
- LOBSTER (NCT07394972)
- Testing
- FeSO4 + meal-matrix, FeSO4 + native LF + meal-matrix, FeSO4 + NaCas-LF + meal-matrix
- Where
- Switzerland
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Nicole Stoffel
Erectile Dysfunction
Effect of Moderate Alcohol on Absorption and Onset of Hezkue Sildenafil Suspension
This is a Phase 2, open-label, randomized crossover study assessing the effect of moderate alcohol intake on the absorption and onset of action of Hezkue® sildenafil oral suspension in adult subjects.
- Trial name
- NCT07290400
- Testing
- Hezkue Sildenafil Oral Suspension, Moderate Alcohol Intake
- Volunteers
- 36 people
- Sponsor
- Aspargo Labs, Inc
Healthy Adults
Differential Absorption Kinetics of Grape Seed Extract Polyphenols
Grape seed extracts (GSEs) contain (poly)phenols that vary in their degree of polymerization, which may lead to differences in absorption, metabolism, and biological efficacy.
- Trial name
- GSE_PK (NCT07886385)
- Testing
- MN-BP Grape Seed Extract, Commercially Available Grape Seed Extract, Gen 2 GSE - Monomer-Enriched
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Clinical Nutrition Research Center, Illinois Institute of Technology
Type 1 Diabetes Mellitus
Effect of Ambient Temperature on Blood Glucose and Insulin Absorption in Adults With Type 1 Diabetes
The goal of this clinical trial is to learn how different temperatures affect blood sugar levels in adults with type 1 diabetes.
- Trial name
- T1Temp (NCT07491133)
- Testing
- Environmental Temperature Exposure
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- Institut de Recherches Cliniques de Montreal
Iron Deficiency (Without Anemia)
Effect of Chitin and Ascorbic Acid on Dietary Insect Iron Absorption
Iron is involved in many vital metabolic processes such as oxygen transport, electron transport in cells, DNA synthesis and repair, and muscle metabolism.
- Trial name
- INSECTE (NCT06822062)
- Testing
- Meal A, Meal B, Meal C
- Where
- Switzerland
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Swiss Distance University of Applied Sciences
Healthy
A Study of LY4515100 in Healthy Male Participants
The main purpose of this study is to evaluate how the body handles [¹⁴C]-LY4515100. The study will investigate how much [¹⁴C]-LY4515100 enters the bloodstream from the stomach or intestines and is available to have an effect on…
- Trial name
- NCT07867327
- Testing
- [¹⁴C]-LY4515100 Oral Solution, LY4515100 Tablet, [¹⁴C]-LY4515100 IV
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Eli Lilly and Company
RDS of Prematurity, Preterm Birth
Pivotal Study to Assess Safety and Performance of Neola®, a Novel Lung Monitoring Device for Neonates
Pivotal study to assess safety and performance of Neola®, a novel lung monitoring device for neonates
- Conditions
- RDS of Prematurity, Preterm Birth, Lung Diseases
- Trial name
- NCT07060911
- Testing
- Lung monitoring with the Neola device
- Where
- 2 sites in United States
- Volunteers
- 22 people
- Sponsor
- Neola Medical Inc
Protein Utilization
Digestion and Absorption of Postbiotic Regulatory Proteins
The goal of this clinical trial is to find out whether a daily postbiotic supplement can help healthy, physically active adults digest and absorb dietary protein better.
- Trial name
- NCT07900204
- Testing
- Inactivated Probiotics
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Wecare Probiotics Co., Ltd.
Adverse Drug Reaction, Therapy Failure
Pharmacogenetic Testing of Patients With Unwanted Adverse Drug Reactions or Therapy Failure
Genetic makeup of a patient influences the efficacy and safety profile of a drug. This study is to summarize individual cases, where Pharmacogenetics (PGx) has been applied during pharmaceutical care.
- Trial name
- NCT04154553
- Testing
- Buccal swab, EDTA Blood sample (4.9mL), Serum sample (7.5mL)
- Where
- Switzerland
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Lung Cancer
Rapid Absorbance-based Detection of Inner Cheek Cell Abnormalities Using Light Spectroscopy for Risk Evaluation of Lung Cancer to Enable Critical Decision Support in Targeted Patient Populations
Overview Sierra Medical is at the forefront of early detection of lung cancer by creating AIR-DS, a non-invasive early detection test.
- Trial name
- RADICAL-REACT (NCT07051044)
- Testing
- AIR-DS
- Where
- 2 sites in United Kingdom
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Sierra Medical Ltd.
Bariatric Surgery Candidate, Kidney Stone
GI Oxalate Absorption
This study aims to learn more about how oxalate, a compound found in many foods, may affect a person's chances of forming kidney stones. Active participation in this study will last for around one week.
- Trial name
- NCT05356000
- Testing
- Special low-oxalate diet followed by all-day visit to University of Chicago research clinic
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Chicago
Drug Absorption
Effect of Gamma-cyclodextrin on the Bioavailability of Berberine
In this study, we will evaluate the relative bioavailability of Berberine (BB) from capsules containing Indian Barberry (Berberis aristate DC.) Bark and Root Extract in the blood plasma of healthy subjects after oral…
- Trial name
- NCT04918667
- Testing
- Berberine incorporated in gamma cyclodextrin, Berberine
- Where
- 4 sites in Armenia, Sweden
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- EuroPharma, Inc.
Iron Absorption, Iron Requirements
Determination of Iron Absorption and Losses in People Living at High Altitude to Investigate the Requirements in This Population Group Using a Newly Developed Technique
Iron is an essential micronutrient responsible for a whealth of biological processes of the human body. Iron plays a fundamental role especially in oxygen transport, by binding to hemoglobin in the blood circulation.
- Conditions
- Iron Absorption, Iron Requirements, Altitude
- Trial name
- ARIA (NCT07142590)
- Testing
- Stable Isotopes
- Where
- Switzerland
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Diego Moretti
Healthy Volunteer
Supplementation Absorption Comparison
The goal of this interventional study is to compare the absorption of supplements with and without absorption enhancing technology in healthy volunteers.
- Trial name
- PHAABS (NCT07791797)
- Testing
- Aquacelle® Omega 3, Comparator Omega 3, Plexosome® Vitamin D3
- Where
- Australia
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- RDC Clinical Pty Ltd
Nutrition, Absorption
Bioavailability From Chickpea Meals in Ileostomists?
The matrix of a food can significantly affect how well humans can absorb and use nutrients. Plants like fruits, vegetables, nuts, grains, and legumes have cell walls that form a network around their cells.
- Conditions
- Nutrition, Absorption, Polyphenolic Compounds and Metabolism, Polyphenols Absorption Profile
- Trial name
- NCT06921811
- Testing
- Intact chickpeas, Broken chickpeas
- Where
- United Kingdom
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- University of Ulster
Pre Diabetes, Metabolic Syndrome
Does Co-administration of Lactate Affect Postprandial Nutrient Absorption and Fat Disposition?
Aim To investigate the effects of oral lactate administration on nutrient absorption and substrate utilization in individuals with pre-diabetes.
- Trial name
- NCT06668714
- Testing
- Lactate + mixed meal, PET-scan, Mixed meal with 18F-FTHA
- Where
- Denmark
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Gut -Microbiota, Inflamation
Impact of a Cricket and Black Soldier Fly Larvae-Fortified Cracker on the Gut Microbiome and Iron Status in Malagasy Schoolchildren
The purpose of this study is to determine the health impacts of consistent consumption of insect-fortified crackers among school-aged children in Madagascar.
- Conditions
- Gut -Microbiota, Inflamation, Iron Absorption
- Trial name
- NCT07439185
- Testing
- Cricket and Black Soldier Fly Larvae-fortified Cracker, Rice and Corn Cracker
- Where
- Madagascar
- Volunteers
- 650 people, healthy volunteers welcome
- Sponsor
- Cornell University
Healthy Adult Participants, ADME
Exploration of Potential Biomarkers of Polyphenol Intake From Artichoke By-product Supplements
The bioavailability study analyzes the absorption, distribution, metabolism, and excretion (ADME) processes of the polyphenols under study (HCAs).
- Conditions
- Healthy Adult Participants, ADME, Polyphenols Absorption Profile, Polyphenolic Compounds and Metabolism
- Trial name
- ARTI-UP ADME (NCT07615673)
- Testing
- Single intake of a supplement derived from artichoke by-products
- Where
- Spain
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Iziar Amaia Ludwig Sanz Orrio
Glucosamine, Liposomal Encapsulation
Human Absorption Study of Liposomal Glucosamine Supplements
The objective of this study is to evaluate the effects of liposomal encapsulation using different ratios of gum arabic and lecithin on the bioavailability of a liquid glucosamine supplement in humans.
- Trial name
- NCT07843342
- Testing
- High-Emulsified Liposomal Glucosamine Liquid, Low-Emulsified Liposomal Glucosamine Liquid, Glucosamine Liquid without Liposomal
- Where
- Taiwan
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- TCI Co., Ltd.
Iron Absorption
Dietary Iron Requirements
Dietary Reference Intakes (DRIs) for iron are based on a relatively small number of studies in European populations. This research study will determine iron needs in a representative sample of adults living in the US using the…
- Trial name
- NCT07139821
- Testing
- Stable iron isotope
- Where
- 2 sites in United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Pennington Biomedical Research Center