Clinical trials: Abuse Tobacco
Tobacco Use Disorder, Diabetes Mellitus, Type 2
Smoking Cessation Program for Adults With Type 2 Diabetes Mellitus (DiMe-SALUD2 Project)
The aim of this study is to analyze the effectiveness and efficiency of a multicomponent smoking cessation intervention for Type 2 Diabetes Mellitus (T2DM) smokers, including a training protocol on healthy lifestyle habits and…
- Trial name
- DiMe-SALUD2 (NCT05885659)
- Testing
- Control group (waiting list), Cognitive Behavioral Treatment (CBT) for smoking cessation, CBT for smoking cessation + DiMeSALUD2 protocol
- Where
- Spain
- Volunteers
- 90 people
- Sponsor
- University of Seville
Tobacco Use Disorder
Role of Metabolites in Nicotine Dependence (4) - 13
The purpose of this study is to determine the effects of cotinine with or without a transdermal nicotine replacement on tobacco withdrawal symptoms.
- Trial name
- NCT00000296
- Testing
- Cotinine fumarate
- Where
- United States
- Sponsor
- National Institute on Drug Abuse (NIDA)
Schizophrenia, Substance Abuse
Screening Protocol for Research Participants
The Screening Protocol is a system devised to evaluate potential research participants for National Institute on Drug Abuse/Maryland Psychiatric Research Center (NIDA/MPRC) studies.
- Conditions
- Schizophrenia, Substance Abuse, Cocaine Abuse, Tobacco Use Disorder
- Trial name
- ScreenProt (NCT01010620)
- Testing
- Various Screening psychiatric and medical assessments
- Where
- United States
- Volunteers
- 523 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Tobacco Dependence, Veterans
Identifying Effective Treatment for Veterans Unwilling to Quit Smoking
This project will generate knowledge about the effectiveness of Enhanced Chronic Care, an intervention designed to enhance treatment use and smoking abstinence in Veterans who are initially unwilling to quit.
- Trial name
- NCT04061720
- Testing
- Enhanced Chronic Care, Standard Care
- Where
- United States
- Volunteers
- 502 people
- Sponsor
- VA Office of Research and Development
Nicotine Dependence
Testing a Full Substitution Therapy Approach As Treatment of Tobacco Dependence
This study will test a new medication strategy designed to help smokers quit. It will combine selegiline, a drug currently approved and available for the treatment of Parkinson's disease, with a nicotine skin patch.
- Trial name
- NCT00390923
- Testing
- Selegiline + nicotine replacement therapy
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- Centre for Addiction and Mental Health
Nicotine Dependence
The Effects of Craving and Abstinence From Cigarettes on Brain Metabolism in Smokers
Craving and withdrawal from smoking cigarettes are major factors for relapse. We investigated craving for cigarettes in smokers undergoing pharmacological treatment with Bupropion (Zyban).
- Trial name
- NCT00267813
- Testing
- Bupropion (Zyban)
- Where
- Israel
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Tel-Aviv Sourasky Medical Center
Nicotine Dependence
Pilot Study of Tolcapone in Smokers
The goals of this within-subject pilot study are: (1) assess the feasibility and safety of administering the Catechol-O-Methyl-Transferase (COMT) inhibitor, tolcapone, to smokers, and (2) explore whether tolcapone may reduce…
- Trial name
- NCT01202955
- Testing
- Tolcapone
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- University of Pennsylvania
Nicotine Dependence
Initial Screening of Gemfibrozil as a Novel Treatment for Tobacco Addiction
The purpose of this study is to investigate the effect of gemfibrozil on nicotine reinforcement and cue-elicited craving. Other objectives of this study include screening for the ability of gemfibrozil to aid smoking abstinence…
- Trial name
- NCT01876810
- Testing
- Gemfibrozil
- Where
- 2 sites in Canada
- Volunteers
- 28 people
- Sponsor
- Centre for Addiction and Mental Health
Breast Cancer, Smoking
Brief Smoking Intervention for Women Undergoing Breast Cancer Surgery
The primary purpose of this study is to examine the effect of a brief preoperative smoking intervention on postoperative complications in women undergoing breast cancer surgery.
- Trial name
- NCT00299117
- Testing
- Brief preoperative smoking intervention
- Where
- 3 sites in Denmark
- Volunteers
- 130 people
- Sponsor
- Herlev Hospital
Tobacco Use Disorder, Bone Fractures
Smoking Cessation and a Teachable Moment in Patients With Acute Fractures
Patients who smoke and suffer from fractures are worse off than those who do not smoke. Orthopaedic patients represent a group that can benefit from physician contributions to smoking cessation, and a special opportunity to cue…
- Trial name
- NCT02781038
- Testing
- Teaching intervention, Control
- Volunteers
- 40 people
- Sponsor
- University of Pennsylvania
Tobacco Use Disorder, Repetitive Transcranial Magnetic Stimulation
fMRI Study of the Neural Mechanism of rTMS in the Treatment of Nicotine Dependence
The goal of this clinical trial is to investigate the efficacy of treatment and the efficacy-related neural network mechanisms by stimulating the left dorsolateral prefrontal lobe with rTMS to nicotine dependent.
- Trial name
- NCT06762535
- Testing
- repetitive transcranial magnetic stimulation
- Where
- China
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Tang-Du Hospital
Alcohol-induced Disorders, Drug Users
SBIRT Implementation for Adolescents in Urban Federally Qualified Health Centers
The purpose of this study is to examine the implementation of two evidence-based intervention strategies of SBIRT (Generalist vs. Specialist) for adolescent alcohol, tobacco, other drug use, and HIV risk behaviors.
- Conditions
- Alcohol-induced Disorders, Drug Users, Tobacco Use Disorder
- Trial name
- ST@T (NCT01829308)
- Testing
- The brief interventions are delivered by behavioral health counselors (Specialist), The brief interventions are delivered by the primary care provider (Generalist)
- Where
- United States
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Friends Research Institute, Inc.
Attention Deficit Hyperactivity Disorder, Nicotine Dependence
Attention Deficit Hyperactivity Disorder (ADHD) Smoking Cessation Study
The overall goal of the present project is to investigate whether lisdexamphetamine (LDX; Vyvanse) is an effective adjunct to nicotine replacement therapy (NRT) to promote smoking cessation in patients with comorbid Attention…
- Trial name
- NCT00736255
- Testing
- Transdermal Nicotine Patch, Lis-dexamphetamine (Vyvanse)
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Duke University
Depression, Smoking
Fluoxetine as a Quit Smoking Aid for Depression-Prone Smokers
This project is a treatment-matching study to test whether adding antidepressant pharmacotherapy to behavioral cessation treatment improves the depression-prone smoker's ability to quit, while not undermining cessation goals for…
- Trial name
- NCT00018174
- Testing
- Fluoxetine, Behavioral group smoking cessation treatment
- Where
- United States
- Volunteers
- 247 people, healthy volunteers welcome
- Sponsor
- US Department of Veterans Affairs
Nicotine Dependence
Prevention of Nicotine Abstinence in Critically Ill Patients After Major Surgery
The primary objective of this study is to determine whether the application of transdermal nicotine patches in critically ill patients after major surgery with nicotine abstinence condition is associated with a lower incidence of…
- Trial name
- NCT03847155
- Testing
- Nicotine patch
- Where
- Czechia
- Volunteers
- 52 people
- Sponsor
- University Hospital Ostrava
Tobacco Dependence, Tobacco Use Cessation
Interactive Mobile Doctor (iMD) to Promote Tobacco Cessation Among Cancer Patients
The proposed pilot study aims to develop and test a patient video educational tool, an interactive Mobile Doctor (iMD), that can be integrated in radiation oncology setting to effectively engage cancer patients receiving…
- Conditions
- Tobacco Dependence, Tobacco Use Cessation, Cancer
- Trial name
- NCT05021185
- Testing
- Interactive Mobile Doctor (iMD)
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of California, San Francisco
Smoking Cessation; Tobacco Dependence
Characterization of Smoking Habits Patterns in Medical Doctors of a Central Hospital in Portugal - What Has Changed After 15 Years? A Comparative Cross-sectional Study
Abstract: Tobacco dependence remains one of the primary health care concerns worldwide. Attitude of healthcare professionals towards smoking is crucial for any long-term prevention and smoking cessation program.
- Trial name
- NCT02913989
- Testing
- Smoking habits characterization
- Volunteers
- 423 people, healthy volunteers welcome
- Sponsor
- Centro Hospitalar Lisboa Ocidental
Cigarette Smoking, Nicotine Dependence
Treatment of Smoking Among Individuals With PTSD
This study will examine the effect of combining prolonged exposure, a cognitive-behavioral treatment program for post-traumatic stress disorder (PTSD) with medication (varenicline) and counseling treatments for smoking cessation.
- Conditions
- Cigarette Smoking, Nicotine Dependence, Post-traumatic Stress Disorder, Tobacco Use Disorder
- Trial name
- NCT00937235
- Testing
- Varenicline, Medication Management Counseling, Prolonged Exposure
- Where
- United States
- Volunteers
- 142 people
- Sponsor
- University of Pennsylvania
Lung Carcinoma, Tobacco Use Disorder
Intermittent or Continuous Acetylsalicylic Acid and Gene Expression in the Nasal Tissue of Current Smokers
This randomized phase II trial studies the safety and effects of acetylsalicylic acid (aspirin) taken continuously or intermittently on gene expression in the nasal tissue of current smokers.
- Trial name
- NCT02123849
- Testing
- Aspirin, Laboratory Biomarker Analysis
- Where
- 2 sites in United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- National Cancer Institute (NCI)
Nicotine Dependence
The Gender-Sex Hormone Interface With Craving & Stress-Related Changes in Smoking
The purpose of the overall parent study is to determine the impact of gender and hormones (estradiol, progesterone, testosterone and cortisol) on responses to stress and smoking cues presented in daily, "real-world" cue…
- Trial name
- SCOR-III (NCT01576874)
- Testing
- Oxytocin
- Where
- United States
- Volunteers
- 144 people
- Sponsor
- Kevin Gray, MD
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