Clinical trials: Abuse Tobacco
Tobacco Use Disorder, Substance Use Disorder
Smoking Cessation CM for Veterans With or at Risk for Cancer
Tobacco use among US Veterans poses significant health problems and challenges to their overall well-being. The aim of this project is to evaluate the effectiveness of a program called Contingency Management (CM) in helping…
- Trial name
- CM_TUD_Cancer (NCT06432985)
- Testing
- Focus Group, Contingency Management (CM), TUD Treatment as Usual (TAU)
- Where
- United States
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Nicotine Dependence
Assessment of High Dose Transdermal Nicotine for Fast Metabolizers of Nicotine
Unfortunately, the investigators still need to assess and identify novel ways to help people quit smoking. Differences between people in terms of how fast they metabolize nicotine influences response to transdermal nicotine…
- Trial name
- HDP (NCT00956943)
- Testing
- Nicoderm CQ transdermal nicotine
- Where
- United States
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Nicotine Dependence
Reactions to Reduced Nicotine Cigarettes in Young Adult Low-Frequency Smokers
The purpose of this study is to evaluate reactions to, and choices to self-administer, cigarette smoke with varying nicotine content among low-frequency, non-dependent adolescent/young adult smokers between the ages of 15-25…
- Trial name
- NicRed (NCT02989038)
- Testing
- Very Low Nicotine Content Cigarettes, Intermediate Nicotine Content Cigarettes, Normal Nicotine Content Cigarettes
- Where
- United States
- Volunteers
- 182 people, healthy volunteers welcome
- Sponsor
- Duke University
Nicotine Dependence, Vaping
Influence of the Consumption of Conventional and Electric Cigarettes on Skin Circulation
The survey participants are divided into a smoking and non-smoking group. The smoker group is further divided according to the quantity and quality of nicotine ("normal" smoking, vaping).
- Conditions
- Nicotine Dependence, Vaping, Smoking
- Trial name
- NCT04645914
- Testing
- Use of nicotine product (smoking/vaping)
- Where
- Germany
- Volunteers
- 198 people, healthy volunteers welcome
- Sponsor
- University Hospital Muenster
Tobacco Dependence
Smoking Cessation Intervention: Effectiveness in Primary Care
The information gathered in this study may help to develop more effective ways to help people quit smoking and stay quit in the future.
- Trial name
- NCT00296647
- Testing
- nicotine patch, nicotine lozenge, bupropion
- Where
- United States
- Volunteers
- 1,346 people
- Sponsor
- University of Wisconsin, Madison
Drug Abuse, Nicotine Dependence
Cognitive Task Development and Implementation for Functional MRI Studies
Background: Drugs of abuse have effects on mood, behavior, thinking, and decision making that may encourage people to continue using them and make it difficult for them to stop.
- Trial name
- NCT01036685
- Where
- United States
- Volunteers
- 525 people, healthy volunteers welcome
- Sponsor
- National Institute on Drug Abuse (NIDA)
Tobacco Use Disorder
Progesterone Treatment in Female Smokers - 12
The purpose of this study is to investigate progesterone effects in female smokers
- Trial name
- NCT00000295
- Testing
- Micronized Progesterone
- Where
- United States
- Sponsor
- National Institute on Drug Abuse (NIDA)
Smoking Cessation, Smoking
Striving to Quit-Wisconsin Tobacco Quit Line
This study is designed to test the hypotheses that incentives can increase both participation in smoking cessation treatment and resulting cessation rates when they are offered to Medicaid BadgerCare Plus members.
- Conditions
- Smoking Cessation, Smoking, Nicotine Dependence
- Trial name
- NCT01569477
- Testing
- Incentives for abstinence and treatment engagement, Attendance incentive
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Drug Abuse, Nicotine Dependence
Advanced Functional and Structural MRI Techniques for Neuropharmacological Imaging
Background: Functional and structural magnetic resonance imaging (MRI) techniques have allowed researchers to map and study how the brain works when at rest and when engaged in specific tasks.
- Trial name
- NCT01036581
- Testing
- MagPro X100 Magnetic Stimulator, Transcranial Rotating Magnetic Stimulator, Magnetom Prisma Fit 3T Scanner
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- National Institute on Drug Abuse (NIDA)
Cannabis Use Disorder, Tobacco Use Disorder
Clinical Trial Tobacco Marijuana
Approximately 50% of persons seeking treatment for cannabis-use disorders (CUDs) regularly smoke tobacco. Combining tobacco with cannabis has become a common method of smoking cannabis.
- Trial name
- RCTTM (NCT02277665)
- Testing
- CUD Treatment, Tobacco Treatment
- Where
- 3 sites in United States
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Dartmouth-Hitchcock Medical Center
Nicotine Dependence
Community-based Smoking Cessation Treatment for Adults With High Stress Sensitivity.
Anxiety sensitivity, reflecting the fear of bodily sensations, is a risk factor for the maintenance and relapse of smoking. This study is designed to address the question - is a smoking cessation intervention personalized to high…
- Trial name
- STEP3 (NCT06053567)
- Testing
- Aerobic Exercise, Counseling, Nicotine patch
- Where
- United States
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- Jasper A. Smits
Smoking Cessation, Tobacco Dependence
Behavioral Therapy for Reduction in Smoking Craving
The objective of this pilot research is to investigate the effects of two behavioral smoking cessation programs on aspects of cue-induced cigarette craving, and to further investigate the neural bases of such effects.
- Trial name
- NCT00449293
- Testing
- standard cognitive behavioral therapy, Mindfulness Based Cognitive Therapy
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Smoking, Smoking Cessation
Biopsychosocial Predictors of Nicotine Relapse
This study aims to investigate the associations between emotion regulation ability, stress-induced neural activity changes, and susceptibility to relapse in smokers attempting to quit.
- Conditions
- Smoking, Smoking Cessation, Nicotine Addiction, Tobacco Smoking Behavior
- Trial name
- BioNic (NCT06470321)
- Testing
- Flexiquit Computerized Smoking Cessation Program
- Where
- Cyprus
- Volunteers
- 200 people
- Sponsor
- University of Cyprus
Tobacco Use Disorder
Smoking Cessation Behavioral Treatment Study
The purpose of this study is to evaluate the effectiveness of two behavioral interventions on smoking behavior - Mindfulness-Oriented Recovery Enhancement (MORE) and Cognitive Behavioral Therapy (CBT).
- Trial name
- NCT03948893
- Testing
- Mindfulness-Oriented Recovery Enhancement (MORE), Cognitive Behavioral Therapy (CBT)
- Where
- 2 sites in United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Nicotine Dependence
Nicotine Replacement Therapy (NRT) and Bupropion Mechanisms of Effectiveness in Smokers
The purpose of this study is to better characterize differences in mood, attention, brain activation patterns underlying the beneficial effects of pharmacological treatments previously demonstrated to be help individuals…
- Trial name
- NCT01048944
- Testing
- Bupropion SR, Nicotine Patch
- Where
- United States
- Volunteers
- 197 people
- Sponsor
- Southern Illinois University Carbondale
Tobacco Use Disorder, Nicotine Dependence
Examining a Text Message Intervention for Smoking Cessation
The primary goal of this study is to use qualitative interviews and focus groups to aid us in adapting a face-to-face smoking cessation intervention for delivery through text messaging.
- Trial name
- NCT01166464
- Testing
- text messaging for smoking cessation, Generic text messages
- Where
- United States
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- The Miriam Hospital
Diabetes Mellitus, Type 2, Nicotine Addiction
Semaglutide for Smoking Cessation in Patients With Diabetes
To assess the feasibility of conducting a randomized controlled trial (RCT) to determine the effectiveness of semaglutide as an adjunct to combination NRT in supporting smoking cessation for patients with diabetes.
- Conditions
- Diabetes Mellitus, Type 2, Nicotine Addiction, Tobacco Dependence
- Trial name
- GLP1-SC (NCT07059377)
- Testing
- Semaglutide, Nicotine replacement
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- Ottawa Heart Institute Research Corporation
Tobacco Use Disorder
Effect of Ramelteon on Smoking Abstinence
This is a randomized, double-blind, placebo-controlled crossover study to test whether a medication called ramelteon (Brand Name: Remeron) will help smokers quit and whether it reduces sleep problems that smokers experience…
- Trial name
- RAP (NCT02560324)
- Testing
- Ramelteon
- Where
- United States
- Volunteers
- 140 people
- Sponsor
- University of Pennsylvania
Nicotine Dependence
Baclofen for Smoking Cessation in a Non-Psychiatric Population
The primary hypothesis for this study is that, in nicotine-dependent tobacco smokers, baclofen will be superior to placebo for smoking abstinence measures.
- Trial name
- Baclofen (NCT01228994)
- Testing
- Baclofen 30 mg/day, Baclofen 60 mg/day
- Where
- Canada
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Centre for Addiction and Mental Health
Tobacco Use Disorder
Transcranial Direct Current Stimulation - Tobacco Use Disorder
This study aims to detect how transcranial direct current stimulation (tDCS) affects smokers' inhibitory control, craving and consumption of tobacco goods.
- Trial name
- NCT03691805
- Testing
- tDCS
- Where
- Germany
- Volunteers
- 44 people
- Sponsor
- Central Institute of Mental Health, Mannheim
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.