Clinical trials: Acceptability
Vaginal Diseases
Assessing the Disintegration, Safety, and Acceptability of Placebo Vaginal Inserts for the Delivery of Vaginal Products
This open-label study will examine the disintegration/disappearance time, safety, and acceptability of placebo vaginal inserts. Participants will use a placebo vaginal insert twice: first for an in-clinic disintegration/safety…
- Trial name
- NCT02534779
- Where
- United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- CONRAD
Insomnia, Cardiovascular Disease
Insomnia and Cardiovascular Diseases: Influence of Behavioral Treatments and Preferences
Research has shown that persons who have trouble sleeping and experience stress are at risk of developing heart diseases. Two treatments, called stimulus control instructions and sleep efficiency treatment, that do not involve…
- Trial name
- NCT02513017
- Testing
- Stimulus Control Instructions and Sleep Restriction Therapy
- Volunteers
- 204 people, healthy volunteers welcome
- Sponsor
- Toronto Metropolitan University
HIV Prevention, Pregnancy Prevention
A Functional Performance Study of The Wondaleaf Female Condom
This research study will determine how well two female condoms perform when used during sex. One of these condoms (FC2) is already commercially available in South Africa.
- Trial name
- NCT04076774
- Testing
- Wondaleaf Female Condom, FC2 Female Condom
- Where
- South Africa
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Prof Mags Beksinska
Hiv
ANRS 12415 - Quali PrEP Cambodia
Hypothesis: Hypothesis 1 : Regarding the recentness of preexposure prophylaxis (PrEP) implementation with an uptake of 20% and according to the first consultative meeting, awareness and acceptability of PrEP seems to be low in…
- Trial name
- ANRS 12415 (NCT05091489)
- Testing
- Qualitative assessment about PrEP acceptability
- Where
- Cambodia
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Institut de Recherche pour le Developpement
Bowel Cancer Screening
Using Patient Navigation to Promote Bowel Screening in AAA Attendees.
The goal of this single-arm, multi-centre feasibility study is to assess the efficacy, feasibility and acceptability of implementing patient navigation across Abdominal Aortic Aneurysm (AAA) screening services in England to…
- Trial name
- TET BETA (NCT07721740)
- Testing
- Patient Navigation conversation
- Where
- United Kingdom
- Volunteers
- 4,190 people, healthy volunteers welcome
- Sponsor
- University of Surrey
Metabolism, Obesity
RMR Monitoring Feasibility and Acceptability
Obesity is a leading risk factor for chronic diseases such as type 2 diabetes, cancer, and cardiovascular disease. Generic weight management programs that target dietary intake and physical activity have been shown to be…
- Conditions
- Metabolism, Obesity, Weight Loss
- Trial name
- NCT06467578
- Testing
- Breezing Portable Indirect Calorimeter
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Dry Eye Syndromes
Efficacy and Acceptability of Two Lubricant Eye Drops
Efficacy and acceptability of two new artificial tears following two weeks of treatment in patients with dry eye. Patients will be randomized to 1 of 2 treatments for 7 days then crossover to the alternate treatment for 7 days.
- Trial name
- NCT00756678
- Testing
- Lubricant Eye Drops (Optive™), Lubricating Eye Drops (blink® Tears)
- Where
- United States
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Allergan
Obesity, Body Image Disorder
Virtual Reality and 3D Reconstruction in Body Image and Bariatrics
With obesity on the rise, the number of metabolic procedures performed annually is also increasing. Bariatric surgery has a significant impact on metabolic disease but also results in significant weight loss.
- Conditions
- Obesity, Body Image Disorder, Bariatric Surgery Candidate
- Trial name
- NCT05273515
- Testing
- Virtual Reality and 3D Reconstruction
- Where
- United Kingdom
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Medical Abortion
Acceptability of an Out-patient Regimen of Medical Abortion With Mifepristone and 800 Mcg Misoprostol Administered at 78-84 Days Gestation
These pilot studies are designed as open label studies to investigate the acceptability of 200 mg mifepristone followed 24-48 hours later by either 1) 800 µg misoprostol administered buccally or 2) 800 µg misoprostol administered…
- Trial name
- NCT01856985
- Testing
- Misoprostol, Mifepristone
- Where
- Vietnam
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Gynuity Health Projects
Infection, Human Immunodeficiency Virus
Study to Evaluate the Safety Tolerability and Acceptability of Long Acting Injections of the Human Immunodeficiency Virus (HIV) Integrase Inhibitor, GSK1265744, in HIV Uninfected Men (ECLAIR)
This study is a Phase IIa, randomized, multi-site, two-arm, double-blinded study to evaluate the safety, tolerability, and acceptability of GSK1265744 long acting injectable formulation (744 LA) in adult male subjects.
- Trial name
- NCT02076178
- Testing
- 744 Tablet, 744 LA Injection
- Where
- 10 sites in United States
- Volunteers
- 127 people, healthy volunteers welcome
- Sponsor
- ViiV Healthcare
Contraception, Malposition of Intrauterine Contraceptive Device
LNG-IUS at 2 Weeks Postpartum
This is a study of 50 postpartum women interested in having the Mirena® LNG-IUS placed for contraception. The Mirena® is an FDA approved intrauterine contraceptive device that provides contraception for 5 years with excellent…
- Trial name
- LNG-IUS (NCT02121067)
- Testing
- Levonorgestrel Intrauterine System (LNG-IUS)
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Volume of Breast Milk Expressed Using Single Electric Breast Pumps., Duration of Exclusive Breast-feeding
Trial of Two Electric Breast Pumps in Mothers of Term Infants.
This is a randomised trial of two modern single electric breast pumps allocated to mothers who are exclusively breast feeding their healthy term infants.
- Conditions
- Volume of Breast Milk Expressed Using Single Electric Breast Pumps., Duration of Exclusive Breast-feeding, Duration of Any Breast-feeding
- Trial name
- NCT02128295
- Testing
- Electric breast pump - A, Electric breast pump - B
- Where
- United Kingdom
- Volunteers
- 228 people, healthy volunteers welcome
- Sponsor
- University College, London
Chlamydia Trachomatis Genital Infection, Gonorrhea
Point of Care Rapid STI Test Optimization and Validation Extension
The purpose of this sub-study (PROVE) is to support and facilitate the validation of commercially available point of care (POC) sexually transmitted infection (STI) diagnostic test kits/devices for potential on-site laboratory…
- Conditions
- Chlamydia Trachomatis Genital Infection, Gonorrhea, Trichomoniasis
- Trial name
- PROVE (NCT06566677)
- Where
- South Africa
- Volunteers
- 364 people, healthy volunteers welcome
- Sponsor
- Wits RHI Research Centre Clinical Research Site
Healthy Participants, Feasibility Studies
The Increasing Mindfulness Engagement Project
The goal of this clinical trial is to examine the feasibility and acceptability of different types of text messages and a integrated gaming app to increase engagement in a mindfulness mobile health application. 1.
- Conditions
- Healthy Participants, Feasibility Studies, Acceptability
- Trial name
- TIMEProject (NCT07170202)
- Testing
- Mindfulness Smartphone Application
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Florida State University
HIV, Alcoholism
Will Having Alcohol Treatment Improve Functioning?
The purpose of the study is to find out if a medication,naltrexone is helpful for HIV-infected women who sometimes drink too much.
- Trial name
- WHAT-IF (NCT01245647)
- Testing
- Naltrexone, 50mg, once per day for 4 months, Sugar pill, 50mg, once per day for 4 months
- Where
- 3 sites in United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- University of Florida
Acceptability of an Exercise Intervention
Exercise Snacking to Improve Strength and STability: ESISST Pilot Study
As we age, muscles can become progressively weaker to the point that tasks of daily living cannot be carried out safely. However, regular resistance exercise training has been shown to maintain and even increase muscle strength…
- Trial name
- ESSIST (NCT05439252)
- Testing
- Exercise Snacking
- Where
- United Kingdom
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- University of Bath
Papillomavirus Vaccines, HPV Vaccinations
HPV Vaccine Integrated Service Implementation Research in Cameroon
The goal of this implementation research study is to understand whether a package of community-based interventions can increase access to and uptake of the human papillomavirus (HPV) vaccine among very young adolescent girls and…
- Conditions
- Papillomavirus Vaccines, HPV Vaccinations, HPV Vaccines, HPV Vaccine Acceptability
- Trial name
- HPV-PASSREV (NCT06683664)
- Testing
- Integrated health service delivery for very young adolescents
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Population Services International
HIV
Safety, Pharmacokinetics and Acceptability of PC-1005 for Vaginal Use
This Phase 1 clinical trial will evaluate MIV-150, a third generation non-nucleoside reverse transcriptase inhibitor, co-formulated with a potentially potent agent, zinc acetate for the prevention of HIV infection in women.
- Trial name
- NCT02033109
- Testing
- PC-1005, HEC gel
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Population Council
Childhood Cancer Survivor
Assessing the Acceptability of the Use of a Mobile Health App Among Young Adult Female Survivors of Childhood Cancer
The purpose of this research study is to understand if a mobile app is useful to assist young adult female survivors of childhood cancer in the self-management of survivorship-related needs.
- Trial name
- NCT03242200
- Testing
- Mobile Health App
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Ulcerative Colitis (UC)
Impact of the Novel UC-TREAT Diet on the Gut Microbiome and Its Acceptability in Healthy Adults and Adults With Quiescent Ulcerative Colitis
This will be an open-label dietary intervention study recruiting both healthy adults (≥16y) and adults with quiescent Ulcerative Colitis (UC).
- Trial name
- UC-TREAT (NCT06998277)
- Testing
- Dietary therapy
- Where
- United Kingdom
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Glasgow