Clinical trials: Acceptability
Overweight and Obesity
An App-based Mindfulness Intervention for Sexual Minority Women With a History of Early Life Adversities (ELA)
Sexual minority women (SMW) in mid-age are at significantly higher risk for obesity, which is associated with greater vulnerability to cardiovascular disease, diabetes, cancer, and mortality.
- Trial name
- NCT05201391
- Testing
- "Eat Right Now" (ERN) mobile application
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Brown University
Oral Anti-Tumor Drugs, Oral Antineoplastic Agents
Educational Intervention on Oral Anticancer Agents for Community Pharmacists
The overall aim of this study is to develop and test the feasibility and acceptability of an educational intervention for community pharmacists to provide support to patients receiving oral anticancer agents (OAAs) in the…
- Conditions
- Oral Anti-Tumor Drugs, Oral Antineoplastic Agents, Oral Anticancer Drugs
- Trial name
- NCT07677176
- Testing
- Educational intervention on managing oral anticancer agents in community pharmacy setting
- Where
- Malaysia
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Monash University Malaysia
Hygiene
Safety Dermatological Evaluation: Acceptability With Gynecological Follow up - Dermacyd Delicata Pocket BR
The purpose of this study is to demonstrate the safety of the gynecological formulation in normal and usual usage condition of Dermacyd Delicata Pocket.
- Trial name
- NCT00663390
- Testing
- Lactic acid (Dermacid)
- Where
- Brazil
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Sanofi
HIV Infections
Safety and Acceptability of PRO 2000 Vaginal Gel in HIV Uninfected Women in India
PRO 2000 Gel is designed to be inserted into the vagina to protect women from getting HIV during sex. So far, PRO 2000 Gel has been tested for safety in 136 women from Europe and the United States.
- Trial name
- NCT00081640
- Testing
- PRO 2000/5 Gel (P)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Pregnancy Related
Feasibility and Acceptability of Butterfly iQ
The purpose of this study is to investigate feasibility and acceptability of a novel intervention to integrate Butterfly IQ into antenatal care (ANC) service delivery in Malawi.
- Trial name
- FAB-IQ (NCT05054504)
- Testing
- Butterfly iQ
- Where
- Malawi
- Volunteers
- 1,575 people, healthy volunteers welcome
- Sponsor
- Jhpiego
Tenofovir
CROSSOVER STUDY OF ON-DEMAND PREP FORMULATIONS COMPARING RECTAL AND ORAL TENOFOVIR
This is a Phase 2, multi-site, two-period, open label randomized crossover (Period 1 and 2) study. Participants are randomized 1:1 to one of two 8-week on-demand product sequences - TFV douche then oral F/TDF or oral F/TDF then…
- Trial name
- NCT06560684
- Testing
- Oral F/TDF Pills, TFV rectal douche
- Where
- 8 sites in United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
HIV Negative and Not Yet on PrEP
PrEP Talk: PrEP Uptake With Young Black MSM and Their Close Friends
Young Black MSM (YBMSM) are at critically high and disproportionate HIV risk. Reducing HIV incidence rates among YBMSM will likely require increased adoption of additional strategies such as pre-exposure prophylaxis (PrEP).
- Trial name
- PrEP-Talk (NCT04601649)
- Testing
- PrEP Talk
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- California State University, Dominguez Hills
Dry Eye Syndromes
Efficacy and Acceptability of Two Lubricant Eye Drops
Efficacy and acceptability of two new artificial tears following two weeks of treatment in patients with dry eye. Patients will be randomized to 1 of 2 treatments for 7 days then crossover to the alternate treatment for 7 days.
- Trial name
- NCT00756678
- Testing
- Lubricant Eye Drops (Optive™), Lubricating Eye Drops (blink® Tears)
- Where
- United States
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Allergan
Preoperative Anxiety Experienced by the Pediatric Patient, Dental Anxiety in Children
Evaluating Operation Calm With Children, Parents, and Clinicians
Operation Calm is a single-arm, mixed-methods feasibility study evaluating a virtual reality (VR) nature-based mindfulness intervention with children and adolescents aged 6-17 years, parents, and clinicians.
- Conditions
- Preoperative Anxiety Experienced by the Pediatric Patient, Dental Anxiety in Children, Procedural Anxiety
- Trial name
- NCT07694934
- Testing
- Operation Calm EEMCF-VR
- Where
- Canada
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- McGill University
Eating Behavior
Effect of Food Acceptability on Appetite Hormones' Response in Normal Weight vs. Obese Male Subjects
Male subjects with specific body characteristics were recruited for the study. Subjects did an acceptability test on custard and completed a screening questionnaire.
- Trial name
- NCT03779321
- Testing
- Acceptability
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- American University of Beirut Medical Center
Gestational Diabetes, Gestational Diabetes Mellitus in Pregnancy
Manchester Intermittent Diet in Gestational Diabetes Acceptability Study
A two-arm non-blinded randomised feasibility protocol trial designed to assess the feasibility, safety, and acceptability of an intermittent low energy diet (ILED) vs best National Health Service (NHS) care in women with…
- Conditions
- Gestational Diabetes, Gestational Diabetes Mellitus in Pregnancy, Intermittent Fasting, Pregnancy Related
- Trial name
- MIDDAS-GDM (NCT05344066)
- Testing
- Best NHS Care, Intermittent Low Energy Diet
- Where
- United Kingdom
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Manchester University NHS Foundation Trust
Meaningful Life
Meaning-focused Intervention in the Army
The purpose of this research is to contribute to the empirical study of meaningful life interventions in the general population, since it is a sample of active professionals.
- Trial name
- NCT05336292
- Testing
- Meaningful life-focused intervention, Meaningful life and emotional regulation-focused intervention, Control Group
- Where
- Spain
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Universidad Complutense de Madrid
Insomnia, Cardiovascular Disease
Insomnia and Cardiovascular Diseases: Influence of Behavioral Treatments and Preferences
Research has shown that persons who have trouble sleeping and experience stress are at risk of developing heart diseases. Two treatments, called stimulus control instructions and sleep efficiency treatment, that do not involve…
- Trial name
- NCT02513017
- Testing
- Stimulus Control Instructions and Sleep Restriction Therapy
- Volunteers
- 204 people, healthy volunteers welcome
- Sponsor
- Toronto Metropolitan University
Induced; Birth, Labor Long
Stimulation Therapy for Inducing Mothers
This is a pilot feasibility and acceptability study of a randomized clinical trial of pregnant women at 36 weeks of gestation and greater randomized to one of two arms at Yale New Haven Hospital: (1) Breast stimulation by hand or…
- Conditions
- Induced; Birth, Labor Long, Labor Pain, Breast Pumping
- Trial name
- STIM (NCT04756089)
- Testing
- Electronic breast pump, Exogenous oxytocin intravenous infusion
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Yale University
HIV Infections, Chlamydia Trachomatis
Safety, Acceptability and Preliminary Effectiveness of Carraguard™ (PC-515) in Preventing HIV/STI Transmission
The primary aims of the study were to assess the safety and acceptability of Carraguard ™ (PC-515) when applied vaginally at least three times weekly for 6-12 months.
- Conditions
- HIV Infections, Chlamydia Trachomatis, Neisseria Gonorrhoeae, Trichomonas Vaginitis
- Trial name
- NCT00213018
- Testing
- Carraguard (PC-515)
- Where
- 2 sites in South Africa
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Population Council
Contraception
Efficacy and Safety Study of the Combined Oral Contraceptive NOMAC-E2 Compared to a COC Containing DRSP/EE (292002)(P05722)
The primary purpose of this study is to assess contraceptive efficacy, vaginal bleeding patterns (cycle control), general safety and acceptability of the nomegestrol acetate-estradiol (NOMAC-E2) combined oral contraceptive (COC)…
- Trial name
- NCT00413062
- Testing
- NOMAC-E2, DRSP-EE
- Volunteers
- 2,281 people, healthy volunteers welcome
- Sponsor
- Organon and Co
Mental Health Wellness 1
Qoyangnuptu: Qoyangnuptu Intervention (QI) App
The goal of this clinical trial is to learn about the impacts of using a mobile health app, the Qoyangnuptu Intervention App (QI App) a Southwestern Tribal Community.
- Trial name
- NCT06254924
- Testing
- QI App Users, Parents/Guardians of QI App Users
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Northern Arizona University
Pregnancy
Effectiveness of BufferGel as a Vaginal Contraceptive
BufferGel is a new contraceptive gel designed to be used with a diaphragm. In addition to preventing pregnancy, BufferGel may also prevent some types of sexually transmitted diseases (STDs).
- Trial name
- NCT00065858
- Testing
- BufferGel
- Where
- 9 sites in United States
- Volunteers
- 975 people, healthy volunteers welcome
- Sponsor
- Premier Research
HIV Prevention
Biktarvy for Non-Occupational Post-Exposure Prophylaxis (nPEP)
Study will evaluate the safety and tolerability of once daily Biktarvy for 28 days for prevention of HIV infection in HIV-1-seronegative adults after high-risk sexual contact. (non-occupational post exposure prophylaxis - nPEP)
- Trial name
- NCT03499483
- Testing
- bictegravir
- Where
- United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Fenway Community Health
Pregnancy Related
Telemedicine Medical Abortion Service Using the "No-test" Protocol in Azerbaijan.
The goal of this study is to pilot and evaluate a telemedicine medical abortion service delivery that allows remote communication between the woman and provider and limits medically unnecessary in-person visits to health or…
- Trial name
- NCT05459142
- Testing
- Medical Abortion
- Where
- Azerbaijan
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Gynuity Health Projects