Clinical trials: Acceptability
Medical Abortion
Acceptability and Feasibility of Medical Abortion in Singapore
To test the hypothesis that a regimen of 200 mg oral mifepristone, with the option of home administration, followed by 800 μg buccal misoprostol 24 hours later for abortion through 70 days LMP will be feasible and acceptable in…
- Trial name
- NCT02985229
- Testing
- Mifepristone, Misoprostol
- Where
- 2 sites in Singapore
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Gynuity Health Projects
Tuberculosis
Male Partner-assisted Contact Tracing for HIV and Tuberculosis in Malawi
The overall aim of the mPATCH-TB Study is to identify potentially cost-effective, feasible and scalable interventions that could increase rates of completion of screening for tuberculosis and HIV among male partners of women…
- Trial name
- mPATCH-TB (NCT04285905)
- Testing
- Access to Fast Track TB clinic, Information leaflet for male partner, Home sputum collection
- Where
- Malawi
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Liverpool School of Tropical Medicine
Patient Participation
Using Patient Feedback in Mental Health Services
Aim: This study aims to assess how feasible and acceptable it is to deliver facilitated team meetings, designed to support mental health teams to listen and learn from patient feedback and how helpful and feasible the evaluation…
- Trial name
- NCT05603325
- Testing
- Person Centered Practice, Interview
- Where
- United Kingdom
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- NHS Grampian
HIV-1-infection
Ending the Epidemic Interventions in the Dental Setting - UH3
The purpose of this study is to use information technology (IT) to support the efficient delivery of HIV prevention and care best practices in the dental care setting.
- Trial name
- ETE (NCT06890988)
- Testing
- Care Navigator, Multicomponent HIV Service Package
- Where
- 3 sites in United States
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Columbia University
HIV, Contraception
Phase I One-month Safety, PK, PD, and Acceptability Study of IVR Releasing TFV and LNG or TFV Alone
The purpose of the study is to evaluate the safety of the TFV/LNG intravaginal ring (IVR), TFV-only IVR, and placebo IVR, evaluate pharmacokinetics (PK) of TFV and LNG, evaluate pharmacodynamic (PD) surrogates of contraceptive…
- Trial name
- NCT02235662
- Testing
- TFV IVR, TFV/LNG IVR
- Where
- 2 sites in United States, Dominican Republic
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- CONRAD
Penile Infection, Penile Haematoma
Evaluation of the Acceptability and Safety of the ShangRing Device for Male Circumcision in Shinyanga, Tanzania
The goal of this observational study was to evaluate the safety and acceptability of the ShangRing device for male circumcision among men in Shinyanga, Tanzania.
- Conditions
- Penile Infection, Penile Haematoma, Penile Bleeding, Deformity
- Trial name
- NCT06273696
- Testing
- ShangRing
- Where
- 2 sites in Tanzania
- Volunteers
- 575 people, healthy volunteers welcome
- Sponsor
- IntraHealth International
Delirium
Improve the Patients' Recovery With Family- Caregivers to End Delirium
This research is being done to find out if patients and caregivers who use the iPREPARED mobile health technology experience less delirium, a type of acute confusion, and if they do experience delirium, the delirium will be less…
- Trial name
- iPREPARED (NCT05118867)
- Testing
- iPREPARED
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Frailty, Malnutrition
Frail2Fit Study: Online Nutrition and Exercise Support for Older Adults With Frailty
Frail2Fit will explore the feasibility of training volunteers to deliver online nutrition, exercise, and behaviour change (supported self-management) to improve the health of older people after discharge from hospital.
- Conditions
- Frailty, Malnutrition, Sedentary Behavior
- Trial name
- NCT05384730
- Testing
- Group nutrition and exercise support
- Where
- United Kingdom
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University Hospital Southampton NHS Foundation Trust
Contraception
Safety,Effectiveness and Acceptability of Sino-implant II in DR
A study to assess the contraceptive effectiveness of Sino-implant (II).
- Trial name
- NCT01594632
- Testing
- Jadelle, Sino-implant (II)
- Where
- Dominican Republic
- Volunteers
- 650 people, healthy volunteers welcome
- Sponsor
- FHI 360
Cervical Cancer
Acceptability and Validity of Self Sampling for High Risk HPV Detection Among Women in Maharashtra
The study goals are, 1. To determine the test characteristics (sensitivity, specificity, positive predictive value, negative predictive value, false positivity rates, false negativity rates) of health personnel collected and self…
- Trial name
- HPV (NCT03386695)
- Testing
- Education by Pamphlets, Health education programme
- Where
- India
- Volunteers
- 1,600 people, healthy volunteers welcome
- Sponsor
- Tata Memorial Hospital
Visceral Leishmaniasis, Kala Azar
Efficacy, Acceptability and Cost-effectiveness of Long Lasting Insecticide Nets (LLIN) in the Prevention of Kala Azar
A cluster-randomized vector control trial in Bihar, India, and neighboring Nepal, will test the efficacy of long-lasting impregnated bednets (LLINs, Permanets) for reducing visceral leishmaniasis incidence.
- Trial name
- KALANET (NCT00318721)
- Testing
- Long Lasting Impregnated Nets (LLIN)
- Where
- 2 sites in India, Nepal
- Volunteers
- 20,000 people, healthy volunteers welcome
- Sponsor
- London School of Hygiene and Tropical Medicine
Diabetes
Clinical Study, Opened, of Cutaneous Acceptability of a Topic Product in Normal Conditions of Use
The measured product in this research is a product for topical use, Laboratoires Mercurochrome Reparador e Protetor. The expected benefit to the use of the product is the improvement in skin hydration as measured by self…
- Trial name
- NCT02695706
- Testing
- Laboratoires Mercurochrome Reparador
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- LM Farma Indústria e Comércio Ltda.
Overweight and Obesity, PreDiabetes
Continuous Glucose Monitors (CGM) for Type 2 Diabetes (T2D) Risk Evaluation
The purpose of this research study is to determine whether continuous glucose monitors (CGM) are a safe, effective, and acceptable way to evaluate type 2 diabetes risk in youth as compared to the standard 2-hour oral glucose…
- Conditions
- Overweight and Obesity, PreDiabetes, Insulin Resistance
- Trial name
- NCT05404711
- Testing
- CGM
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Mary Ellen Vajravelu, MD
Healthy
Safety and Acceptability of SPL7013 Gel (VivaGel™) in Sexually Active Women
There is an urgent need for HIV prevention methods that women can initiate and control themselves. Topical microbicides, substances that kill microbes, represent one such method.
- Trial name
- NCT00442910
- Testing
- 3% SPL7013 Gel (VivaGel)
- Where
- 3 sites in United States, Puerto Rico
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Starpharma Pty Ltd
HIV Prevention
Acceptability and Performance of HIV Self-Testing in a Youth Population in Nigeria
The purpose of this study is to evaluate the acceptability and performance of a directly assisted oral HIV self-testing (HIVST) program in a youth population aged 14-24 in Nigeria.
- Trial name
- NCT03874663
- Testing
- Directly assisted oral HIV self-testing (HIVST)
- Where
- Nigeria
- Volunteers
- 652 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Focus: Uterus Transplant Procedure, Acceptability of the Uterus Transplantation Procedure
Uterus Transplantation: Acceptability of the Procedure in Eligible Patients
This study aims to define the knowledge and acceptability of uterine transplantation in patients suffering from infertility due to congenital or acquired absence of this organ, which are followed up in the U.O.C.
- Trial name
- NCT06799728
- Where
- Italy
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Dementia
Sharing the Outcome of a Memory Assessment
The purpose of this study is to establish the acceptability of a guide developed to improve people's experiences of dementia assessment outcome appointments in comparison to a standard consultation.
- Trial name
- NCT04935060
- Testing
- A guide to inform the process of delivering the outcomes of a dementia assessment, Usual Care
- Where
- 2 sites in United Kingdom
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Disease Type and/or Category Not Applicable
Effectiveness of Light for Enhancement of Cognition by Transcranial Repeated Application (ELECTRA)
Aim: Investigate whether transcranial photobiomodulation (tPBM) using near-infrared light exposure to the head, can improve frontal lobe executive function, working memory and overall mood in normal volunteer participants.
- Trial name
- ELECTRA (NCT02817061)
- Testing
- Omnilux
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Tooth Discoloration
Efficacy of a Whitening Dentifrice on Tooth Discoloration
The purpose of this study was to compare the whitening effect of a toothpaste containing blue pigment with a conventional toothpaste and with at-home tooth bleaching; evaluate the subject's perception about tooth color…
- Trial name
- NCT02741427
- Testing
- Conventional toothpaste, Whitening toothpaste, 10% carbamide peroxide
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Federal University of Paraíba
Safety, Acceptability
MATRIX-002: Trial to Assess Acceptability and Safety of Two Placebo Vaginal Films
This study will enroll approximately 100 HIV-negative persons, aged18-45 years, and assigned female sex at birth from sites in the United States, Kenya, South Africa, and Zimbabwe.
- Conditions
- Safety, Acceptability, Usability
- Trial name
- NCT06046053
- Where
- 5 sites in United States, Kenya and 2 more
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Rohan, Lisa, PhD