Clinical trials: Acceptability Study
Medication Palatability
Acceptability of Various Available Midazolam Formulations (Syrup, Rectal Suppository, Oro-dispersible Minitablet) in Clinical Practice
This observational study aims to gain knowledge on how the different midazolam formulations (oral syrup, rectal suppository, ODMT) are accepted by 2- to 10-year-old pediatric inpatients and outpatients at the University…
- Trial name
- NCT05894057
- Testing
- Data collection on acceptability of midazolam administration by 2- to 10-year-old pediatric patients at UKBB
- Where
- Switzerland
- Volunteers
- 100 people
- Sponsor
- University Children's Hospital Basel
75 Years Old and More, Cancer
Tool for the Detection of Oncogeriatric Fragility in Patients Aged ≥75 Years Undergoing Oncological Treatment.(D-FOG)
Many cancers are diagnosed after 75 years. Treatment in chemotherapy begins without evidence of geriatric risk factors. A new tool for screening for geriatric fragilities is used, a self-administered questionnaire carried out by…
- Conditions
- 75 Years Old and More, Cancer, Chemotherapy
- Trial name
- D-FOG (NCT03261128)
- Testing
- Self-questionnaire
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Poitiers University Hospital
HIV
Lopinavir/r/ Lamivudine/ Abacavir as an Easy to Use Paediatric Formulation
A phase I/II, open label, randomized crossover pharmacokinetic, safety and acceptability study of the Abacavir/Lamivudine/ Lopinavir/Ritonavir (30/15/ 40/10mg ;4-in-1) Fixed-Dose Combination vs.
- Trial name
- LOLIPOP (NCT03836833)
- Testing
- ABC/3TC/LPV/r granules (30/15/40/10 mgs), LPV/r Pellets (40/10mgs) plus ABC/3TC (60/30mgs)
- Where
- 3 sites in Uganda
- Volunteers
- 50 people
- Sponsor
- Drugs for Neglected Diseases
Fever, Pain
Paracetamol Oral Paediatric Suspension at 4.8% : Study of Acceptability and Safety.
Evaluate the acceptability over 24 hours of a new paracetamol formulation 4.8% paediatric oral suspension in children weighing between 3 and 26 kg including limits
- Trial name
- NCT00434681
- Testing
- paracetamol 4.8% paediatric oral suspension
- Where
- France
- Volunteers
- 48 people
- Sponsor
- Sanofi
Phenylketonurias, Hyperphenylalaninaemia
PKU Low Calorie Drink Study
This study will evaluate the compliance, acceptability, gastrointestinal (GI) tolerance and safety of a lower calorie amino acid based liquid protein substitute for patients with Phenylketonuria (PKU) or hyperphenylalaninemia…
- Trial name
- NCT04272736
- Testing
- Low calorie protein substitute
- Sponsor
- Nutricia UK Ltd
Pulmonary Disease, Chronic Obstructive
A Study on Whether Patients Prefer the Spiriva® Respimat® or the Spiriva® Handihaler® for Treating Their Chronic Obstructive Pulmonary Disease (COPD)
The objective of this study is to investigate the patient acceptability/preference of Respimat® compared with Handihaler® in patients with moderate to very severe chronic obstructive pulmonary disease (COPD) to demonstrate the…
- Trial name
- NCT03964207
- Testing
- Tiotropium Respimat® (T1), Tiotropium Handihaler® (T2)
- Where
- 8 sites in China
- Volunteers
- 72 people
- Sponsor
- Boehringer Ingelheim
Depression, Cancer
Evaluating Procedures for a Study of the AYA Survivors Coping and Emotional Needs Toolkit
The investigators developed a digital intervention that aims to help adolescent and young adult cancer survivors (AYAs) manage symptoms of depression.
- Conditions
- Depression, Cancer, Adolescent, Young Adult
- Trial name
- ASCENT (NCT06420193)
- Testing
- AYA Survivors Coping and Emotional Needs Toolkit (ASCENT)
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- East Carolina University
Typical Development, Typically Developing Children Ages 3 to 6
Assessment of Language Comprehension and Learning in Children Attending Child Psychiatry Services (TICOALA-SOINS)
Language is central to children's cognitive, emotional, and social development, and language difficulties are a frequent reason for consultation in child psychiatry, often co-occurring with psychiatric disorders.
- Conditions
- Typical Development, Typically Developing Children Ages 3 to 6, Typical Preschoolers Who Can Not Zipper, Children
- Trial name
- TICOALA-SOINS (NCT07283458)
- Testing
- TICOALA
- Where
- France
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier St Anne
Social Skills, Emotional Dysfunction
Feasibility and Acceptability Off The Equus Effect
The VA Office of Patient Centered Care and Cultural Transformation's Whole Health initiative promotes the use of complementary and integrative health (CIH) approaches with traditional medical care to help Veterans achieve…
- Trial name
- NCT04159506
- Testing
- mindfulness, emotion didactics, interpersonal skills, experiential learning
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- VA Office of Research and Development
Oncology
A Study to Determine the Feasibility and Acceptability of Conducting a Phase III Randomised Controlled Trial Comparing Stereotactic Ablative Radiotherapy With Surgery in paTients With Peripheral Stage I nOn-small Cell Lung Cancer cOnsidered Higher Risk of Complications From Surgical Resection
Stage I non-small cell lung cancer (NSCLC) is curable and surgery is considered the standard of care for fit, good performance status patients.
- Trial name
- SABRTOOTHv1 (NCT02629458)
- Testing
- Treatment by Surgical resection, Stereotactic Ablative Radiotherapy (SABR)
- Where
- United Kingdom
- Volunteers
- 54 people
- Sponsor
- The Leeds Teaching Hospitals NHS Trust
Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8
Integrative Approaches for Cancer Survivorship (IACS3)
This clinical trial is a two-arm pilot randomized controlled trial for non-metastatic breast cancer survivors to determine the feasibility, acceptability, and fidelity of two integrative health approaches and study design in a…
- Conditions
- Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage III Breast Cancer AJCC v8
- Trial name
- NCT06633926
- Testing
- Nutrition Education, Lifestyle Counseling, Yoga
- Where
- 4 sites in United States
- Volunteers
- 107 people
- Sponsor
- University of California, San Francisco
Birth; Prolonged
Acceptability Assessment of an Optimized Birthing Position
This qualitative study evaluates the acceptability of positioning pregnant women in labour in an optimized position, which consists in the hyperflexion of the legs and the loss of the lumbar lordosis.
- Trial name
- NCT04056793
- Testing
- Optimized birthing position
- Where
- Switzerland
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire Vaudois
Medical Abortion
Medical Abortion at Gestational Age of 8 to ≤9 Weeks Versus >9 to ≤12 Weeks
The purpose of this study is to assess the effectiveness, safety, and acceptability of home-administered medical abortion at gestational age of 8 to ≤9 weeks versus >9 to ≤12 weeks among a cohort of women in Mexico City.
- Trial name
- NCT02745093
- Testing
- Mifepristone, Misoprostol
- Where
- 3 sites in Mexico
- Volunteers
- 648 people
- Sponsor
- Ibis Reproductive Health
Chronic Musculoskeletal Pain
Feasibility, Acceptability And Usability Of The InControl Web Platform - A Rando Mized Parallel-Group Pilot Study of Mixed-methods
This is a randomized, parallel-group pilot study that employs mixed methods (qualitative and quantitative approaches). The purpose of this study is to assess the feasibility, usability, and acceptability of an intervention with a…
- Trial name
- InControl (NCT07774416)
- Testing
- InControl intervention, Usual Care
- Volunteers
- 34 people
- Sponsor
- Aveiro University
HIV-1-infection
D²EFT Graphical Informed Consent
D²EFT-GIC is a substudy of D²EFT study (NCT03017872), a randomised clinical trial of second-line antiretroviral therapies. The goal of D²EFT-GIC is to evaluate a novel tool, the "Graphical Informed Consent" (GIC), within D²EFT.
- Trial name
- D²EFT-GIC (NCT04668443)
- Testing
- Graphical Informed Consent (GIC)
- Where
- Nigeria
- Volunteers
- 12 people
- Sponsor
- Kirby Institute
Epilepsy Intractable, Glucose Transporter Type 1 Deficiency Syndrome
Evaluation of Ketoflo
For 28 days, 30 participants aged 3 to 18 years of age (inclusive) with a condition requiring a ketogenic diet will incorporate Ketoflo into their usual dietary regime.
- Conditions
- Epilepsy Intractable, Glucose Transporter Type 1 Deficiency Syndrome, Ketogenic Dieting
- Trial name
- Ketoflo (NCT04399954)
- Testing
- Ketoflo
- Where
- 5 sites in United Kingdom
- Volunteers
- 25 people
- Sponsor
- Vitaflo International, Ltd
Alcohol Use Disorder
A Feasibility and Acceptability Study of a Large Language Model-based Chatbot for Brief Alcohol Intervention Among Emerging Adults
American emerging adults (EAs; aged 18-29 years) have the highest rates of alcohol use disorder (AUD) and the lowest levels of treatment engagement of any age group.
- Trial name
- NCT07214831
- Testing
- Large language model-based chatbot brief alcohol intervention session
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Massachusetts General Hospital
HIV Prevention, Pregnancy Prevention
A Functional Performance Study of The Wondaleaf Female Condom
This research study will determine how well two female condoms perform when used during sex. One of these condoms (FC2) is already commercially available in South Africa.
- Trial name
- NCT04076774
- Testing
- Wondaleaf Female Condom, FC2 Female Condom
- Where
- South Africa
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Prof Mags Beksinska
HIV Infections, Acquired Immunodeficiency Syndrome
An Expanded Safety Study of Dapivirine Gel 4759 in Africa
The purpose of this study is to determine whether dapivirine gel 4759 is safe for daily use by healthy women in Kenya, Malawi, Rwanda, South Africa and Tanzania.
- Trial name
- NCT00917891
- Testing
- dapivirine
- Where
- 10 sites in Kenya, Malawi and 3 more
- Volunteers
- 280 people, healthy volunteers welcome
- Sponsor
- International Partnership for Microbicides, Inc.
Psychiatric Disorder
Evaluation of a Modularized Cognitive Behavioral Group Therapy Programme for Young Adults (CHANGE-Study)
This prospective, non-randomised, pre-post feasibility study evaluates CHANGE, a novel 8-session modularized cognitive behavioral group psychotherapy for young adults (18-25 years) with psychiatric disorders receiving inpatient…
- Trial name
- CHANGE (NCT07772180)
- Testing
- CHANGE - modularized group psychotherapy
- Where
- Germany
- Volunteers
- 30 people
- Sponsor
- Max-Planck-Institute of Psychiatry