Clinical trials: Acceptance and Commitment Therapy
Inflammatory Bowel Diseases, Crohn's Disease
ACT for Veterans With IBD and Mental Health Challenges
Many Veterans with gastrointestinal disorders, such as inflammatory bowel disease (IBD), also have mental health conditions. IBD and mental health conditions can worsen one another through the brain-gut axis, leading to dramatic…
- Conditions
- Inflammatory Bowel Diseases, Crohn's Disease, Ulcerative Colitis, Depressive Disorder
- Trial name
- RECLAIM (NCT07397195)
- Testing
- Acceptance and Commitment Therapy
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- VA Office of Research and Development
Post-surgical Pain, Pain, Acute
Online Psychology Program for Chronic Pain After Surgery
This project will evaluate the feasibility of a new fully self-guided online Acceptance and Commitment Therapy (ACT) program entitled Advancing Online Psychology Tools for the Transitional Pain Service (ADOPT-TPS), developed on…
- Conditions
- Post-surgical Pain, Pain, Acute, Pain, Chronic, Post-Surgical Pain, Chronic
- Trial name
- ADOPT-TPS (NCT06455345)
- Testing
- Self-Guided Online ACT Program, Treatment As Usual
- Where
- 2 sites in Canada
- Volunteers
- 68 people
- Sponsor
- University Health Network, Toronto
Chronic Musculoskeletal Disease
Acceptance and Commitment Therapy, a Mindfulness-Based Approach for Treatment of Chronic Musculoskeletal Pain
Acceptance and Commitment Therapy (ACT) has been recognized as an effective, non-pharmacologic treatment for a variety of CP conditions. However, little is known about the neurologic mechanisms underlying ACT.
- Trial name
- NCT04502992
- Testing
- Acceptance and Committment Therapy
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- University of New Hampshire
Chronic Pain
Acceptance and Commitment Therapy With and Without Enhanced Mindfulness Training for Chronic Pain
As non-pharmacological alternatives, psychosocial treatments have been recommended for chronic pain management. One such treatment is Acceptance and Commitment Therapy (ACT).
- Trial name
- MUST (NCT04057144)
- Testing
- ACT, mindfulness exercises and audio recordings, Education program
- Where
- 4 sites in Norway
- Volunteers
- 667 people
- Sponsor
- St. Olavs Hospital
Exhaustion Disorder, Stress-Related Disorders
Step by Step Back - A Feasibility Study of a Physical Activity Intervention for Adults With Stress-related Exhaustion
The goal of this clinical study is to learn whether a psychologist- or psychotherapist-guided physical activity program can be delivered and used as part of regular care for adults experiencing stress-related exhaustion.
- Trial name
- NCT07407829
- Testing
- CBT/ACT-based psychologist-delivered physical activity program
- Where
- Sweden
- Volunteers
- 20 people
- Sponsor
- The Swedish School of Sport and Health Sciences
Schizophrenia, Delusional Disorder
Acceptance and Commitment Therapy for Delusions
Symptoms of schizophrenia have historically been treatment resistant despite advances in psychopharmacology. Acceptance and Commitment Therapy (ACT) has been shown through some preliminary research to be effective with psychotic…
- Trial name
- ACT (NCT00657631)
- Testing
- Acceptance and Commitment Therapy
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Weill Medical College of Cornell University
Problem Gambling
Brief ACT Intervention for Problem Gambling: A Pilot Study
The goal of this pilot study is to learn if Acceptance and Commitment Therapy (ACT) works to treat Problem Gambling in young adults.The main questions it aims to answer are: Does ACT therapy improve health and gambling behavior?…
- Trial name
- NCT07066488
- Testing
- Acceptance and Commitment Therapy (ACT)
- Where
- Spain
- Volunteers
- 5 people
- Sponsor
- Universidad Europea de Madrid
End-stage Renal Disease, Depression
Feasibility RCT of ACT Self-help for Depression in Haemodialysis
The purpose of this study is to assess the feasibility of conducting a trial to evaluate a self-help treatment for depression in people with end-stage renal disease.
- Trial name
- NCT02565056
- Testing
- Self help book + telephone support
- Where
- 3 sites in United Kingdom
- Volunteers
- 9 people
- Sponsor
- University of Lincoln
Chronic Pain
A New Approach in Chronic Pain; Acceptance & Commitment Therapy-Exposure & Perspective Taking (ACT-EPT)
Background: Chronic pain is a highly prevalent phenomenon with a large impact on the individual's wellbeing. Acceptance and Commitment Therapy (ACT) can be used to help patients relate to chronic pain in a way that helps improve…
- Trial name
- ACT-EPT (NCT03481504)
- Testing
- Acceptance & Commitment Therapy-Exposure and Perspective Taking
- Where
- Netherlands
- Volunteers
- 3 people
- Sponsor
- Maastricht University Medical Center
Autism Spectrum Disorder, Attention Deficit Disorder With Hyperactivity (ADHD)
Pai.ACT: AI-Driven ACT Chatbot for Mental Health Triage and Service Evaluation
Parents of children with special needs in Hong Kong often face limited psychological support, which can negatively impact the child rehabilitation process and the well-being of parent-child relationships.
- Conditions
- Autism Spectrum Disorder, Attention Deficit Disorder With Hyperactivity (ADHD), Neurodevelopmental Disorder (Diagnosis), Dyslexia
- Trial name
- NCT06808555
- Testing
- Pai.ACT Group, Control Group
- Where
- 20 sites in Hong Kong
- Volunteers
- 340 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Smoking Cessation, Schizophenia Disorder
Effects of Smoking on Network Connectivity in Patients With Schizophrenia Symptoms in Scz Patients
The prevalence of smoking among people with schizophrenia (SCZ) is substantially higher at 54% to 90% (McClave et al., 2010). About half of all deaths amongst people with scz are attributed to smoking-related diseases and cancer…
- Trial name
- ACT (NCT07441928)
- Testing
- Acceptance and Commitment Therapy (ACT-SC), 5A model (Ask, Assess, Advice, Assist & Arrange) smoking cessation intervention (5A-SC)
- Where
- 5 sites in Hong Kong
- Volunteers
- 90 people
- Sponsor
- The Hong Kong Polytechnic University
Lung Cancer, Advanced Cancer
Acceptance and Commitment Therapy on Fatigue Interference in Patients With Advanced Lung Cancer and Caregiver Burden (ACT)
Lung cancer is a malignant tumour that has transformed from a single cancer disease into one of the most striking global health problems.
- Conditions
- Lung Cancer, Advanced Cancer, Caregiver Burden
- Trial name
- NCT05885984
- Testing
- Acceptance and Commitment Therapy (ACT) plus health education, Health education
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Chinese University of Hong Kong
COVID-19, Mental Health Disorder
Treatment of Post-covid Syndrome in Patients Treated in Intensive Care
The present study is a pilot randomized controlled trial, which identifies and diagnoses mental health problems in survivors of critical COVID-19 infection at 12 months post-ICU care, and randomize patients to either an…
- Trial name
- NCT05119608
- Testing
- CBT/ACT
- Where
- 2 sites in Sweden
- Volunteers
- 40 people
- Sponsor
- Region Skane
Mild Cognitive Impairment (MCI)
Instant Message-delivered Personalised Acceptance and Commitment Therapy (ACT) for Neuropsychiatric Symptoms in Persons With Mild Cognitive Impairment
This pilot study aims to develop an automated instant message-delivered intervention (i.e., EMI) for people with mild cognitive impairment, and to investigate the feasibility and effectiveness of the intervention.
- Trial name
- iact (NCT07332624)
- Testing
- Automated instant message-guided neuropsychiatric symptoms management
- Where
- Hong Kong
- Volunteers
- 40 people
- Sponsor
- The University of Hong Kong
Pediatric Palliative Care, Caregiver Burden
The Effect of Watson Human Care Theory and Acceptance and Commitment Therapy-Based Counseling Program Applied to Parents of Pediatric Palliative Care Patients on Value-Based Life and Care Burden
This study aims to examine the effect of Watson Human Care Theory and Acceptance and Commitment Therapy-based counseling program applied to parents of pediatric palliative care patients on value-oriented living and care burden.
- Conditions
- Pediatric Palliative Care, Caregiver Burden, Acceptance and Commitment Therapy
- Trial name
- NCT07327580
- Testing
- Counseling Program Based on Watson Human Care Theory and Acceptance and Commitment Therapy (ACT)
- Where
- Turkey (Türkiye)
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Necmettin Erbakan University
Opioid-Related Disorders, Psychosocial Functioning
Developing a Smartphone Application to Support Veteran Opioid Use Disorder Treatment
Opioid Use Disorder (OUD) is a complex, chronic condition affecting nearly 70,000 Veterans who can experience significantly reduced quality of life (e.g., poorer social, occupational, and health-related functioning).
- Conditions
- Opioid-Related Disorders, Psychosocial Functioning, Quality of Life
- Trial name
- NCT06454903
- Testing
- ACT to RECOVER, Smartphone-based Symptom-Monitoring
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- VA Office of Research and Development
PTSD, Post Traumatic Stress Disorder PTSD
Clinical Trial of MDMA-Assisted Therapy for Military Service Members With Posttraumatic Stress Disorder
This study is a Phase 2, randomized, double-blind, active-controlled, two-arm, single-site clinical trial designed to evaluate the safety, tolerability, and feasibility of MDMA-Assisted Therapy (MDMA-AT) for Service Members…
- Conditions
- PTSD, Post Traumatic Stress Disorder PTSD, Post Traumatic Stress Disorder
- Trial name
- NCT07704762
- Testing
- TREATMENT ARM: Full dose, CONTROL ARM: Active-controlled
- Volunteers
- 86 people
- Sponsor
- U.S. Army Medical Research and Development Command
Cystic Fibrosis
Acceptance and Commitment Therapy vs. Supportive Psychotherapy With Cystic Fibrosis Patients
The objective of the study is to assess the utility of "Acceptance and Commitment Therapy" (ACT) in which subjects learn new ways to manage uncomfortable experiences and feelings and to engage in positive behaviors, over…
- Trial name
- NCT04114227
- Testing
- Acceptance and Commitment Therapy adapted for Cystic Fibrosis (ACT with CF), Supportive Psychotherapy (Treatment as Usual Control)
- Where
- United States
- Volunteers
- 146 people
- Sponsor
- Thomas Jefferson University