Clinical trials: Access Complication
Mitochondrial Disease, Chronic Kidney Disease
Expanded Access Program for R007 (Probucol) Tablets in Adults With Mitochondrial Disease and Chronic Kidney Disease
The purpose of this expanded access program is to enable access to R007 (probucol) tablets for the compassionate treatment of adults with mitochondrial disease who also have chronic kidney disease.
- Trial name
- NCT06931834
- Testing
- Probucol
- Where
- United States
- Sponsor
- RiboNova Inc.
Atrial Fibrillation, Peripheral Vascular Disease
Ultrasound-guided Femoral Vein Accessibility, Safety and Time for Atrial Fibrillation Treatment
This study is designed to evaluate the use of real-time ultrasound-guided femoral venipuncture during pulmonary vein isolation for treating atrial fibrillation .
- Conditions
- Atrial Fibrillation, Peripheral Vascular Disease, Vascular Access Complications
- Trial name
- ULTRA-FAST (NCT02834221)
- Testing
- Real-time ultrasound-guided puncture, Anatomical landmark guided puncture
- Where
- 4 sites in Czechia, Japan
- Volunteers
- 320 people
- Sponsor
- Kenichiro Yamagata
Severe Aortic Stenosis, TAVI\(Transcatheter Aortic Valve Implantation\)
VARC-TAVI VALVE IMPLANTATION)
SUMMARY: The investigators are planning a clinical study to compare two methods of performing a procedure called TAVI, used in patients with severe aortic stenosis.
- Conditions
- Severe Aortic Stenosis, TAVI\(Transcatheter Aortic Valve Implantation\), Vascular Complications
- Trial name
- VARC-TAVI (NCT06177392)
- Testing
- Secondary TAVI access
- Volunteers
- 600 people
- Sponsor
- Hospital Universitario La Paz
Kidney Failure, Chronic
Arteriovenous Fistula Tissue Bank for Pre- and Post-Fistula Placement Specimens
This project will bank sera, DNA and vascular specimens from patients undergoing arteriovenous fistula creation and revision.
- Trial name
- NCT00836862
- Testing
- Biologic specimens
- Where
- United States
- Volunteers
- 43 people
- Sponsor
- University of Nebraska
Clear Cell Renal Cell Carcinoma
89Zr-DFO-girentuximab Expanded Access Program (EAP)
The purpose of this Expanded Access Program (EAP) is to enable the use of 89Zr-DFO-girentuximab with positron emission tomography/computed tomography (PET/CT) imaging to non-invasively detect carbonic anhydrase 9…
- Trial name
- NCT06090331
- Testing
- 89Zr-DFO-girentuximab
- Where
- 22 sites in United States
- Sponsor
- Telix Pharmaceuticals (Innovations) Pty Limited
Breast Cancer, Ovarian Cancer
A Study Of TeleGenetics Versus Usual Care To Increase Access To Cancer Genetic Services
The goal of this research is to evaluate the relative advantage of remote counseling over usual care in community health practices without access to genetic services.
- Conditions
- Breast Cancer, Ovarian Cancer, Colorectal Cancer
- Trial name
- NCT02517554
- Testing
- Penn genetic counselors provides counseling and test results disclosure by videoconferene to patient at community site, Penn genetic counselor provides counseling and test results disclosure by telephone to patient at community site, Patient receives written information on how to find genetic services in their area
- Where
- 7 sites in United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Abramson Cancer Center at Penn Medicine
Vascular Access Complication, Radial Artery
Feasibility and Safety of the Routine Distal Transradial Approach
The distal transradial approach (dTRA) via the anatomical snuffbox is hypothesized to be more beneficial than the conventional transradial access (cTRA) in patients undergoing coronary procedures.
- Conditions
- Vascular Access Complication, Radial Artery, Coronary Artery Disease, Puncture
- Trial name
- ANTARES (NCT05982366)
- Testing
- distal radial artery acess side, conventional radial artery acess side
- Where
- Poland
- Volunteers
- 400 people
- Sponsor
- Łukasz Koziński
Difficult Intravenous Access, Adults
Ultra-Long Peripheral Catheter Versus Accelerated Seldinger Technique Long Peripheral Catheter in Difficult IV Access Patients
The aim of this study is to perform a comparative analysis of clinical outcomes associated with the use of an ultra-long peripheral catheter using (catheter-over-the-needle technique) versus an AST-long peripheral catheter in…
- Trial name
- ULAST (NCT07005310)
- Testing
- Powerglide pro™, Introcan safety deep access
- Where
- Belgium
- Volunteers
- 100 people
- Sponsor
- University Ghent
Complement 3 Glomerulopathy
A Study of Complement 3 Glomerulopathy (C3G) Patients Treated With Iptacopan Through an Early Access Program in Spain
This study aims to characterize the patient profiles and the clinical experience of iptacopan treatment in adult patients with C3G treated through an early access program (EAP) in Spain.
- Trial name
- ROUTE-C3G (NCT07598448)
- Where
- 2 sites in Spain
- Volunteers
- 35 people
- Sponsor
- Novartis Pharmaceuticals
Renal Stones, Retrograde Intrarenal Surgery
Tamsulosin and Intraureteral Aminophylline for Ureteral Access During RIRS
This multicenter randomized controlled trial will evaluate whether preoperative tamsulosin, intraureteral aminophylline, or their combination can improve ureteral access during primary retrograde intrarenal surgery for renal…
- Conditions
- Renal Stones, Retrograde Intrarenal Surgery, Ureteral Access Sheath Placement
- Trial name
- TAM-AMIN-UAS (NCT07623876)
- Testing
- Tamsulosin, Intraureteral Aminophylline
- Where
- 3 sites in Egypt
- Volunteers
- 322 people
- Sponsor
- Beni-Suef University
C3G, IC-MPGN
C3G/Primary IC-MPGN EAP
This is an Early Access Program (EAP) which will provide access to pegcetacoplan for eligible participants with C3G and Primary IC-MPGN.
- Conditions
- C3G, IC-MPGN, C3 Glomerulopathy, C3 Glomerulonephritis
- Trial name
- NCT04729062
- Testing
- Pegcetacoplan
- Sponsor
- Apellis Pharmaceuticals, Inc.
NMIBC
ResQ132EX-NMIBC: Expanded Access Use of Recombinant Bacillus Calmette-Guérin in Nonmuscle Invasive Bladder Cancer
This expanded access protocol is designed to provide Recombinant Mycobacterium BCG (rMBCG) to patients with Non-muscle invasive bladder cancer (NMIBC) who are eligible to receive TICE® BCG, may benefit from its use, and who are…
- Trial name
- NCT06810141
- Testing
- rMBCG
- Where
- 66 sites in United States
- Sponsor
- ImmunityBio, Inc.
End Stage Renal Disease, Thrombosis
Access II - Trial of Warfarin to Prevent Malfunction of Haemodialysis Catheters
This study examines whether low intensity, dose adjusted warfarin prolongs the time to mechanical failure of hemodialysis catheters without resulting in an unacceptable rate of bleeding.
- Conditions
- End Stage Renal Disease, Thrombosis, Bleeding
- Trial name
- NCT00157651
- Testing
- warfarin
- Where
- Canada
- Volunteers
- 170 people
- Sponsor
- Hamilton Health Sciences Corporation
End Stage Renal Disease
Study to Evaluate the Performance and Safety of Expedial and Compare it to Expanded Polytetrafluoroethylene (ePTFE) Vascular Access Grafts
The purpose of this study is to establish the substantial equivalence of Expedial and ePTFE grafts for effectiveness in maintaining primary or assisted primary patency.
- Trial name
- NCT00131872
- Testing
- Expedial Vascular Access Graft
- Where
- 8 sites in United States
- Volunteers
- 172 people
- Sponsor
- LeMaitre Vascular
Procedural Related Injuries and Complications Nec, Patient Satisfaction
Radial Versus Femoral Arterial Access for Cerebral Angiography in Adolescents
This study will compare radial vs femoral access for angiography in adolescents. Neuroangiography and neurointerventions are predominantly performed via femoral access, which has several limitations and complications - pain and…
- Trial name
- NCT04604340
- Testing
- transradial access for neuroangiography, transfemoral access for neuroangiography
- Where
- Canada
- Volunteers
- 12 people
- Sponsor
- The Hospital for Sick Children
Stone, Kidney
Evaluation of Retrograde Intra Renal Surgery in the T-tilted Position
To evaluate the effect of the T-tilted position on the stone-free rate compared to the standard lithotomy position in retrograde intrarenal surgeries.
- Trial name
- RIRS (NCT06860113)
- Testing
- T-tilting of the patient during surgery, standard lithotomy position
- Where
- Egypt
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
End Stage Renal Failure, Hemodialysis Access Failure
Outcomes for One-stage and Two-stage Brachial Basilic Arteriovenous Fistulas
An arteriovenous (AV) fistula is essential for patients with kidney failure on dialysis. There is no clear data on the best method to create a new brachial basilic AV fistula (BBAVF), so the choice between a single procedure and…
- Conditions
- End Stage Renal Failure, Hemodialysis Access Failure, Arterio-venous Fistula
- Trial name
- NCT04376567
- Testing
- One stage approach
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Tze-Woei Tan
Endovascular Procedures
Safety and Accuracy of the Saranas EBBMS for the Detection of Endovascular Procedure Related Bleeding Events
To evaluate the safety and accuracy of the Saranas EBBMS for the detection of access site related internal bleeding events during large-bore endovascular procedures.
- Trial name
- NCT03621202
- Testing
- Saranas Early Bird Bleed Monitoring System (EBBMS)
- Where
- 5 sites in United States
- Volunteers
- 66 people
- Sponsor
- Saranas, Inc.
Vascular Access Complication
RADIAL Versus Femoral Access for Coronary Artery Bypass Graft Angiography and Intervention (RADIAL-CABG) Trial
Increased use of radial access for cardiac catheterization is being advocated because studies have showed lower arterial access related complication rates and higher patient satisfaction as compared to femoral access.
- Trial name
- RADIAL-CABG (NCT01446263)
- Testing
- Radial access versus femoral access for coronary angiography and intervention
- Where
- United States
- Volunteers
- 128 people
- Sponsor
- North Texas Veterans Healthcare System
Chronic Kidney Diseases, Hemodialysis
Must Cannulation Technique of Vascular Access in Patients Undergoing Haemodialysis: Contributions for a Safe Nursing Intervention
The aims of this study are to: Determine the AVF (arteriovenous fistula) survival of patients submitted to MuST compared to those submitted to RL (rope-ladder).
- Conditions
- Chronic Kidney Diseases, Hemodialysis, Vascular Access Complication, Hemodialysis Access Failure
- Trial name
- MuST (NCT05081648)
- Testing
- CT MuST, Rope-ladder cannulation technique
- Where
- 3 sites in Portugal
- Volunteers
- 101 people
- Sponsor
- Fresenius Medical Care Deutschland GmbH