Clinical trials: Access Complication
Parenteral Nutrition Associated Liver Disease
Omegaven Expanded Access Protocol
Omegaven is an intravenous fat emulsion (IFE) comprised of omega-3 fatty acids derived from fish oil. It will be used in an open label compassionate use treatment protocol, as an alternative to soybean oil (omega-6), as the sole…
- Trial name
- NCT02121769
- Testing
- Omegaven
- Where
- United States
- Sponsor
- St. Luke's Health System, Boise, Idaho
End-Stage Renal Disease
Decellularized Femoral Artery Allograft (Nexeon AVX) Prospective Registry
Post market registry to assess the safety and efficacy of a novel decellularized human femoral artery allograft (Nexeon AVX Decellularized Femoral Artery,
- Trial name
- NCT05880537
- Testing
- Nexeon Arterial Venous Allograft
- Where
- 4 sites in United States
- Volunteers
- 100 people
- Sponsor
- LifeNet Health
Patient Satisfaction, Vascular Access Complication
Radial vs. State-Of-The-Art Femoral Access for Bleeding and Access Site Complication Reduction in Cardiac Catheterization (REBIRTH)
This is a phase IV, prospective, open label, randomized-controlled study that will compare radial access with state-of-the-art femoral access in patients without ST-segment elevation acute myocardial infarction undergoing cardiac…
- Trial name
- REBIRTH (NCT04077762)
- Testing
- Radial Access, State-of-the-art femoral access with 18 gauge needle, State-of-the-art femoral access with 21 gauge needle
- Where
- 6 sites in United States
- Volunteers
- 3,266 people
- Sponsor
- Minneapolis Heart Institute Foundation
Postoperative Hemorrhages
Prospective Registry on Vascular Access in Interventions in Lazio Region
Previous randomised studies showed that radial artery catheterisation for percutaneous cardiovascular procedures has a superior safety profile than femoral access, however the confirmation of these benefits in the real world by a…
- Trial name
- PREVAIL (NCT00674778)
- Testing
- Any percutaneous cardiovascular procedure
- Volunteers
- 1,052 people
- Sponsor
- San Filippo Neri General Hospital
Kidney Diseases, ESRD
Safety and Efficacy of Angiotech Vascular Wrap Paclitaxel-Eluting Mesh for Hemodialysis Vascular Access
This is a multi-center clinical study in subjects requiring arteriovenous grafts in the upper extremity for hemodialysis access. All subjects will provide informed consent before undergoing any study procedures.
- Trial name
- NCT00448708
- Testing
- Vascular Wrap Paclitaxel-Eluting Mesh, Lifespan® ePTFE Vascular Graft
- Where
- 33 sites in United States
- Volunteers
- 222 people
- Sponsor
- Angiotech Pharmaceuticals
Chronic Kidney Diseases
ODYSSEE Kidney Health Trial
INTRODUCTION Severe CKD is defined as a risk of greater than 10% for progressing to RRT [home hemodialysis (HHD), home peritoneal dialysis (HPD), and transplantation] within 2 years.
- Trial name
- ODYSSEE-KH (NCT06274710)
- Testing
- ODYSSEE-KH
- Where
- Canada
- Volunteers
- 344 people
- Sponsor
- University Health Network, Toronto
Early Pregnancy Loss, Early Pregnancy
Conversational Artificial Intelligence (AI) to Improve PeRiconception Care Access
The goal of this project, Conversational Artificial Intelligence (AI) to Improve PeRiconception Care Access (CIRCA), is to engage patients in care early in pregnancy (before prenatal care starts) and safely triage concerns to…
- Trial name
- CIRCA (NCT06618144)
- Testing
- Texting platform
- Where
- United States
- Volunteers
- 350 people
- Sponsor
- University of Pennsylvania
Kidney Stones
Steerable vs Conventional FANS for <2cm Lower Pole Stone Treatment: SCULPT Trial
This multicenter, randomized, controlled superiority trial (the SCULPT trial) aims to compare the efficacy and safety of a novel steerable flexible and navigable suction ureteral access sheath (FANS) versus the conventional FANS…
- Trial name
- NCT06898216
- Testing
- Steerable FANS, Conventional FANS
- Where
- China
- Volunteers
- 400 people
- Sponsor
- The First Affiliated Hospital of Guangzhou Medical University
Vascular Access Complication, Coronary Artery Disease
Efficacy and Safety of the Distal Radial Approach
The aim of this non-inferiority trial is to determine if the distal radial access (DRA) during percutaneous coronary intervention (PCI) has an acceptable efficacy compared to the reference access through the conventional radial…
- Trial name
- TunDRA (NCT05311111)
- Testing
- distal radial artery approach, conventional radial artery approach
- Where
- Tunisia
- Volunteers
- 250 people
- Sponsor
- General Administration of Military Health, Tunisia
Premature Birth
Exploring the Feasibility of Centering Pregnancy With Care Navigation
Pacific Islanders residing in the United States (US) have disproportionally high rates of preterm birth (<37 weeks) and low birthweight infants (<2,500 grams).
- Trial name
- NCT05645549
- Testing
- Centering Pregnancy with Care Navigation
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- University of Arkansas
Urolithiasis
COMPARISON OF FANS VS CONVENTIONAL URETERAL ACCESS SHEATH in RIRS on POSTOPERATIVE ACUTE KIDNEY INJURY
Kidney stone disease is a common condition, and retrograde intrarenal surgery (RIRS) is a minimally invasive procedure frequently used to remove kidney stones.
- Trial name
- FANS (NCT07685587)
- Testing
- flexible and navigable ureteral access sheath, conventional ureteral access sheath
- Where
- Turkey (Türkiye)
- Volunteers
- 108 people
- Sponsor
- Namik Kemal University
Sedative Adverse Reaction, Analgesic Adverse Reaction
The Use of Midazolam and Remifentanil During Dialysis Access Procedures
BACKGROUND: Sedation and analgesia are related to unexpected adverse events in chronic renal failure patients undergoing arteriovenous fistula placement procedures under monitored anesthesia care (MAC).
- Conditions
- Sedative Adverse Reaction, Analgesic Adverse Reaction, Midazolam Adverse Reaction, Adverse Reaction to Drug
- Trial name
- NCT04226443
- Testing
- Midazolam intravenous injection, Remifentanil intravenous bolus dose
- Volunteers
- 99 people
- Sponsor
- Kartal Kosuyolu Yuksek Ihtisas Education and Research Hospital
Vascular Access Complications
Application of Vascular Closure Device in Transvenous Cardiac Intervention
Comparison of safety and efficacy between the application of vascular closure device and conventional figure-of-eight suture in transvenous cardiac interventional surgery
- Trial name
- NCT05521100
- Testing
- Vascular closure device, figure eight stitch
- Where
- China
- Volunteers
- 160 people
- Sponsor
- Shanghai 10th People's Hospital
Kidney Failure
Aggrenox Prevention of Access Stenosis
The objective of the study is to determine whether Aggrenox (Boehringer-Ingelheim) prolongs primary unassisted patency in newly created arteriovenous grafts.
- Trial name
- GRAFT (NCT00067119)
- Testing
- Aggrenox
- Where
- 9 sites in United States
- Volunteers
- 649 people
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
End Stage Renal Disease, Vascular Access Complication
Bicarbonate vs Heparin Catheter Lock in Chronic Hemodialysis Patients
Prospective clinical trial to evaluate the efficacy of catheter lock with bicarbonate vs heparin in chronic hemodialysis patients.
- Conditions
- End Stage Renal Disease, Vascular Access Complication, Catheter Complications, Hemodialysis Access Failure
- Trial name
- BICATH (NCT04054128)
- Testing
- Sodium Bicarbonate 7.5% Injection, Heparin Sodium, 1000 Units/mL Injectable Solution 1
- Where
- Mexico
- Volunteers
- 60 people
- Sponsor
- Hospital General "Dr. Miguel Silva" de Morelia
PCNL
Novel Technique for PCNL Access
Benha modification for renal track creation in percutaneous nephrolithotomy (PCNL) Our modification aims to decrease the complications of PCNL in large stones
- Trial name
- NCT05640219
- Testing
- laparoscopic trocar 12mm
- Volunteers
- 30 people
- Sponsor
- Benha University
Ovarian Cancer
A Trial of Fast Access to Transvaginal Ultrasound Through General Practice for Earlier Diagnosis of Ovarian Cancer
Background Ovarian cancer (OC) is a disease with a poor prognosis due to diagnosis at late stage. Early-stage OC presents with non-specific and vague symptoms and therefore OC usually is not detected until reaching an advanced…
- Trial name
- NCT03069872
- Testing
- Transvaginal ultrasound
- Where
- Denmark
- Volunteers
- 490 people
- Sponsor
- University of Aarhus
Pancreatic Cancer, Osteosarcoma
BLESSED: Expanded Access for DNG64-CAR-V for Advanced Pancreatic Cancer, Sarcoma and Carcinoma of Breast
Forty patients with pancreatic cancer, sarcoma and carcinoma of breast will receive DNG64-CAR-V intravenously or intratumorally at a dose of 1-4 x 10e11 colony forming units (cfu) or equivalent 1.0-6.0 x 10e10 Vector Copies (VC)…
- Conditions
- Pancreatic Cancer, Osteosarcoma, MPNST (Malignant Peripheral Nerve Sheath Tumor), Chondrosarcoma
- Trial name
- NCT04091295
- Testing
- DNG64-CAR-V
- Where
- United States
- Sponsor
- Aveni Foundation
Suture, Complication
Fixing the Short Stay Central Venous Catheter: Comparison of Two Techniques
Context: The central venous catheter is used in intensive care units for several indications, including the administration of drugs with sclerosis potential, infusion solutions and hemodynamic monitoring.
- Trial name
- NCT02932800
- Testing
- Fixation with "ballerina" technique and flip, Habitual Fixation, Evaluation on the third and fift days, filogisticos and infectious signs, fixing loss, and culture
- Where
- Brazil
- Volunteers
- 62 people
- Sponsor
- Universidade do Vale do Sapucai
Cervical Cancer
Capecitabine in Treating Patients With Advanced, Persistent, or Recurrent Cervical Cancer
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. PURPOSE: Phase II trial to study the effectiveness of capecitabine in treating patients who have advanced…
- Trial name
- NCT00016926
- Testing
- capecitabine
- Where
- 10 sites in United States, Norway
- Sponsor
- Gynecologic Oncology Group