Clinical trials: Access Complication
Urolithiasis
A Prospective Comparison of Fluoroscopic, Sonographic or Combined Approach for Renal Access in Percutaneous Nephrolithotomy
Purpose: The aim of this present study is to compare the result of fluoroscopy, ultrasonography (US) and US combined with fluoroscopy in the guidance of minimally invasive percutaneous nephrolithotomy (MPCNL).
- Trial name
- NCT02266381
- Testing
- US-guided renal access, Fluoroscopy-guided renal access, US combined with fluoroscopy-guided renal access
- Where
- China
- Volunteers
- 450 people
- Sponsor
- The First Affiliated Hospital of Guangzhou Medical University
Nephrolithiasis, Kidney Stone
HoYAG vs TFL in miniPCNL With ClearPetra
Mini percutaneous nephrolithotripsy is the treatment of choice for kidney stones over 2cm. This procedure commonly uses laser energy for breaking the stones, and among possible laser platforms, Hoyag and thulium fiber laser are…
- Trial name
- NCT07087977
- Testing
- HoYAG laser, TFL laser platform
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- University of Kansas Medical Center
Mitochondrial Disease, Chronic Kidney Disease
Expanded Access Program for R007 (Probucol) Tablets in Adults With Mitochondrial Disease and Chronic Kidney Disease
The purpose of this expanded access program is to enable access to R007 (probucol) tablets for the compassionate treatment of adults with mitochondrial disease who also have chronic kidney disease.
- Trial name
- NCT06931834
- Testing
- Probucol
- Where
- United States
- Sponsor
- RiboNova Inc.
Tracheostomy Complication, Emergency Front of Neck Airway in Children
Neck Rescue Access Comparison
Emergency front-of-neck access (eFONA) represents the final lifesaving intervention in a pediatric "can't intubate, can't oxygenate" scenario.
- Conditions
- Tracheostomy Complication, Emergency Front of Neck Airway in Children, Anesthesia
- Trial name
- eFONA (NCT07368179)
- Testing
- Percutaneous Seldinger-Guided Tracheal Access (Melker), scalpel-bougie tracheostomy
- Where
- Switzerland
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Kidney Failure, Chronic, Kidney Transplantation
Immunological Reset to Enable Access to Hla-compatible Kidney Transplantation in Highly Sensitized Patients (RESET)
The purpose of this clinical trial is to evaluate whether a temporary reprogramming of the immune system can help highly sensitized (hyperimmunized) patients with end-stage kidney disease safely receive a compatible kidney…
- Conditions
- Kidney Failure, Chronic, Kidney Transplantation, Alloimmunization, HLA Sensitization
- Trial name
- HIPER-RESET (NCT07607197)
- Testing
- Autologous Hematopoietic Stem Cell Transplantation
- Where
- Spain
- Volunteers
- 10 people
- Sponsor
- Hospital Universitari Vall d'Hebron Research Institute
Uremic Pruritus
Intermediate-Size Patient Population Expanded Access Program for Intravenous Difelikefalin
This is an intermediate-size patient population expanded access protocol for the use of intravenous (IV) difelikefalin for the treatment of moderate-to-severe pruritus associated with chronic kidney disease in adult patients…
- Trial name
- NCT05031546
- Testing
- Difelikefalin
- Sponsor
- Cara Therapeutics, Inc.
Kidney Failure
Aggrenox Prevention of Access Stenosis
The objective of the study is to determine whether Aggrenox (Boehringer-Ingelheim) prolongs primary unassisted patency in newly created arteriovenous grafts.
- Trial name
- GRAFT (NCT00067119)
- Testing
- Aggrenox
- Where
- 9 sites in United States
- Volunteers
- 649 people
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Cushing's Disease, Acromegaly
Study to Allow Access to Pasireotide for Patients Benefiting From Pasireotide Treatment in Novartis-sponsored Studies
The purpose of this study is to allow continued use of pasireotide in patients who are on pasireotide treatment in a Novartis-sponsored study and are benefiting from the treatment as judged by the investigator.
- Conditions
- Cushing's Disease, Acromegaly, Neuroendocrine Tumors, Pituitary Tumors
- Trial name
- NCT01794793
- Testing
- Pasireotide, Cabergoline, Pasireotide LAR
- Where
- 94 sites in United States, Argentina and 26 more
- Volunteers
- 337 people
- Sponsor
- RECORDATI GROUP
Hyponatremia, Hyponatremia With Extracellular Fluid Depletion
Hypotonic Hyponatremia: Criteria for the Correct Classification of Its Etiology and of Patient Volume Status
Hyponatremia is the most frequent electrolyte disorder encountered in clinical practice. The patient approach, however, is still problematic, above all because hyponatremia is a manifestation correlated to various pathological…
- Conditions
- Hyponatremia, Hyponatremia With Extracellular Fluid Depletion, Hyponatremia With Normal Extracellular Fluid Volume, Hyponatremia With Excess Extracellular Fluid Volume
- Trial name
- NCT04402190
- Where
- Italy
- Volunteers
- 123 people
- Sponsor
- A.O.U. Città della Salute e della Scienza
Renal Stone Disease, Renal Stones
Flexible Ureteroscopy With Novel Flexible Ureteral Access Sheath Versus Mini-Percutaneous Nephrolithotomy for Treatment of 2-3cm Lower Calyceal Renal Stones
The aim of the study is to compare the efficacy, safety, and patient outcomes of flexible ureteroscopy with a novel flexible ureteral access sheath and mini-percutaneous nephrolithotomy in the treatment of 2-3 cm lower calyceal…
- Conditions
- Renal Stone Disease, Renal Stones, Flexible Ureteroscopy, Mini Percutaneous Nephrolithotomy
- Trial name
- NCT07904676
- Testing
- Flexible Ureteroscopy with Novel Flexible Ureteral Access Sheath, Mini-Percutaneous Nephrolithotomy
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Ain Shams University
Vascular Access Devices, Vascular Access
Impact of a Long Peripheral Venous Catheter Protocol in Pediatric and Neonatal Care
The purpose of this study is to evaluate the impact of a training intervention aimed at nursing personnel on the appropriateness of the indication of long peripheral venous catheters in candidate pediatric and neonatal patients…
- Conditions
- Vascular Access Devices, Vascular Access, Vascular Access Complication
- Trial name
- NCT07870876
- Testing
- Training program on long peripheral catheter insertion
- Volunteers
- 33 people
- Sponsor
- Instituto de Investigación Sanitaria de la Fundación Jiménez Díaz
Stone;Renal, Stone, Urinary
Comparison Between Two Methods for Renal Stone Treatment Mini Percutaneous Nephrolithotomy and Flexible Ureteroscopy With Suction Sheath
This study aims to compare the efficacy and safety of two modern, minimally invasive surgical techniques for the removal of kidney stones: Mini-Percutaneous Nephrolithotomy (Mini-PCNL) and Flexible Ureteroscopy (FURS) with…
- Conditions
- Stone;Renal, Stone, Urinary, Stone, Kidney, Stone Clearance
- Trial name
- mini-PCNL/FANS (NCT07306819)
- Testing
- mini-percutaneous nephrolithotomy, Flexible Uerteroscopy with Tip-Bendable Suction Sheath
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Ain Shams University
Vascular Access, Vascular Access Complication
Novel Medical Device for Pharmacological Therapy
Background: Different co-creation methods were used to design and prototype a new fixative device for multiple intravenous therapies with the ability to control and identify the pharmacological therapy administered to a patient.
- Conditions
- Vascular Access, Vascular Access Complication, Vascular Access Complications, Catheter Malfunction
- Trial name
- Sechold (NCT06938750)
- Testing
- SECHOLD DEVICE
- Where
- Spain
- Volunteers
- 262 people
- Sponsor
- Fundacion Miguel Servet
Vascular Access Complication
Near-infrared Software Performance Study
This study will look at the performance capabilities of software for VeinViewer.
- Trial name
- NCT02200458
- Testing
- VeinViewer
- Where
- United States
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Christie Medical Holdings, Inc.
End-stage Renal Disease, Kidney Failure, Chronic
Evaluation of the Safety and Efficacy of a Vascular Prosthesis for Hemodialysis Access in Patients With ESRD
The purpose of this study is to assess the safety and efficacy of a novel, tissue-engineered vascular prosthesis, the Human Acellular Vascular Graft, HAVG.
- Trial name
- NCT01744418
- Testing
- HAVG graft implantation
- Where
- 3 sites in Poland
- Volunteers
- 40 people
- Sponsor
- Humacyte, Inc.
Non Small Cell Lung Cancer, Ovarian Cancer
Continued Access to RXDX-105
This study is being done to see if people with Non-Small Cell Lung Cancer (NSCLC) or ovarian cancer benefit from continued treatment with the study drug, RXDX-105.
- Conditions
- Non Small Cell Lung Cancer, Ovarian Cancer, RET Gene Mutation, BRAF Gene Mutation
- Trial name
- NCT03784378
- Testing
- RXDX-105
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Kidney Stone
Prospective Multi-center Study Comparing Pulsed Tm:YAG Laser to Pulse Modulated Holmium Laser in the Treatment of Nephrolithiasis With FANS Access Sheaths
The purpose of this study is to compare two laser technologies that are routinely used during ureteroscopy for the treatment of kidney stones.
- Trial name
- NCT07516106
- Testing
- Moses Holmium:YAG laser, Thulium:YAG laser
- Where
- 2 sites in United States
- Volunteers
- 70 people
- Sponsor
- NYU Langone Health
Renal Calculi
FANS VS DISS in Treatment of Renal Stone < 2cm
To compare between FANS \& DISS in : Operative time Stone free rate Complications Amount of fluid irrigation
- Trial name
- NCT07559214
- Testing
- Flexible ureteroscopy
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Assiut University
Chronic Kidney Disease
Expanding and Promoting Alternative Care and kNowledge in Decision-making Trial
The goal of this clinical trial is to compare two health system-based approaches for offering kidney failure treatment options to older patients with kidney failure, specifically, to ensure patients are actively involved in a…
- Trial name
- ExPAND (NCT06243068)
- Testing
- Educate and Engage, Educate and Engage Plus Kidney Supportive Care Program
- Where
- 25 sites in United States
- Volunteers
- 3,000 people
- Sponsor
- George Washington University
Genetic Disease, Genetic Syndrome
Ensuring Patients' Informed Access to Noninvasive Prenatal Testing
Noninvasive prenatal genetic testing (NIPT) is an important new screening test option provided to pregnant women in the first trimester of pregnancy.
- Conditions
- Genetic Disease, Genetic Syndrome, Prenatal Disorder, Prenatal Maternal Abnormality
- Trial name
- NEST (NCT03420274)
- Testing
- NEST, Usual care
- Where
- 2 sites in United States
- Volunteers
- 691 people
- Sponsor
- The Cleveland Clinic