Clinical trials: Access and Evaluation
Mental Disorders
Reducing Stigma Among Healthcare Providers to Improve Mental Health Services
A growing number of trials have demonstrated treatment effectiveness for people with mental illness (PWMI) by non-specialist providers, such as primary care and community health workers, in low-resource settings.
- Trial name
- RESHAPE-mh (NCT02793271)
- Testing
- RESHAPE, PRIME/mhGAP
- Where
- Nepal
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Brandon A Kohrt, MD, PhD
Venipuncture
Clinical Evaluation of an AI- and Ultrasound-Assisted Venipuncture Device
Purpose : This study aims to confirm the safety and efficacy of AIIV L2, an artificial intelligence- and ultrasound-based medical device that assists venipuncture, by comparing venipuncture performed using AIIV L2 with manual…
- Trial name
- NCT07383870
- Testing
- AIIV L2, Manual venipuncture
- Where
- South Korea
- Volunteers
- 190 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Quantity and Variety of Vegetables Consumed
ENSAND 2.0 Evaluation in Nigeria
The Enhancing Access to Safe and Nutritious Diets 2.0 (ENSAND) (2024-2026) project is designed to address the low per capita consumption of vegetables and variety of vegetable consumption in northern Nigeria by working with…
- Trial name
- NCT06927661
- Testing
- Consumption of vegetables
- Where
- Nigeria
- Volunteers
- 1,568 people, healthy volunteers welcome
- Sponsor
- RTI International
Colon Disease, Gastric Disease
Feasibility Trial to Evaluate the Ability of the SuMO Tissue Access and Resection System
This feasibility trial will evaluate the ability of the SuMO Tissue Access and Resection System (Apollo Endosurgery, Austin, Texas).
- Trial name
- SUMO (NCT01322737)
- Testing
- Tissue Access and Resection System
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- University Hospitals Cleveland Medical Center
Pregnancy
Michigan Contraceptive Access, Research, and Evaluation Study: Phase 1
M-CARES will use large-scale administrative data complemented by follow-up surveys and a randomized control trial (RCT) to estimate the causal impact of greater financial access to contraception on a comprehensive set of…
- Trial name
- M-CARES (NCT03673007)
- Testing
- Gift card to be used for contraceptives that is valued at 50% of cost of name-brand IUD (August 26, 2018-March 3, 2019), Gift card to be used for contraceptives that is valued at 100% of cost of name-brand IUD (March 4, 2019-March 31, 2023)
- Where
- 9 sites in United States
- Volunteers
- 4,633 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Chronic Periodontitis
Evaluation of Antimicrobial Photodynamic Therapy in Multiple Applications as a Coadjuvant in the Surgical Therapy of Access to Scaling
Chronic periodontitis is an infectious disease resulting in inflammation of the teeth support structures, progressive periodontal attachment loss and bone loss.
- Trial name
- NCT03498404
- Testing
- Photodynamic Therapy, scaling and root planing
- Where
- Brazil
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
HIV - Human Immunodeficiency Virus
HIV Prevention With PrEP Among People on Opioid Replacement Therapy
The purpose of this study is to assess the feasibility and acceptability of providing oral pre-exposure prophylaxis (PrEP) and opioid agonist therapy (OAT) simultaneously in existing pharmacy-based programs operating in Alberta…
- Trial name
- OAT-PrEP (NCT07160075)
- Testing
- Simultaneous administration of OAT and oral PrEP at existing pharmacy-based programs
- Where
- 6 sites in Canada
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- Cara Spence
Health Care Quality, Access, and Evaluation, Delivery of Health Care
Improving HIV Screening With Nurse-Based Rapid Testing/Streamlined Counseling
Background: HIV testing is cost-effective in unselected general medical populations, yet testing rates among those at-risk remain low, even among those with regular primary care.
- Conditions
- Health Care Quality, Access, and Evaluation, Delivery of Health Care, Immune System Diseases, HIV Infections
- Trial name
- NCT00119548
- Testing
- Rates of HIV testing and receipt of results, Sexual risk reduction; HIV knowledge improvement
- Where
- United States
- Volunteers
- 251 people, healthy volunteers welcome
- Sponsor
- US Department of Veterans Affairs
HIV
Operational Assessment of Point-of-Care Diagnostics in Primary Healthcare Clinics
Diagnostic point-of-care (POC) tests are being rapidly developed and implemented in resource-limited settings. There has been a rapid rise of HIV and TB POC tests in South Africa during the last 10-15 years.
- Trial name
- NCT02692274
- Where
- South Africa
- Volunteers
- 309 people, healthy volunteers welcome
- Sponsor
- University of KwaZulu
Contraception
Adherence With Continuous-dose Oral Contraceptive: Evaluation of Self-Selection and Use
This study is designed to assess whether consumers select and use norgestrel 0.075 mg, a progestin only pill for contraception, in a manner consistent with the OTC package directions in an Over-the-Counter (OTC)-like setting.
- Trial name
- ACCESS (NCT04112095)
- Testing
- Norgestrel 0.075 mg tablets
- Where
- 38 sites in United States
- Volunteers
- 962 people, healthy volunteers welcome
- Sponsor
- HRA Pharma
Peripheral Venous Access
Development and Evaluation of an Algorithm for Vascular Access Management
Two billion catheters are placed annually worldwide. Of all the people requiring vascular access, nearly a quarter have Difficult Intravenous access (DIVA), a source of multiple punctures.
- Trial name
- ALCOV (NCT05935228)
- Testing
- Implementation of the A-DIVA Scale, Implementation of the algorithm composed of the A-DIVA Scale and the new decision-making tree (the A-DIVA Tool) in the centers
- Where
- France
- Volunteers
- 794 people, healthy volunteers welcome
- Sponsor
- Central Hospital, Nancy, France
Quality of Care
Electricity Access and Maternal Care in Rural Health Facilities in Uganda
The investigators will conduct a stepped wedge cluster-randomized controlled trial in maternity care facilities in Uganda to evaluate the impact of the provision of a reliable light source on the quality of delivery care…
- Trial name
- NCT03589625
- Testing
- Solar Suitcase
- Where
- Uganda
- Volunteers
- 1,268 people, healthy volunteers welcome
- Sponsor
- Harvard School of Public Health (HSPH)
Gingival Recession
Comparison of Using Collagen Membrane and A-PRF Using VISTA Technique in Gingival Recession Treatment
To assess the efficacy of minimally invasive Vestibular Incision Subperiosteal Tunnel Access (VISTA) with collagen membrane and Advanced Platelet-rich Fibrin (A-PRF) in the treatment of multiple buccal gingival recession type…
- Trial name
- NCT06357351
- Testing
- vestibular incision sub periosteal tunnel access ( VISTA) technique.
- Where
- Egypt
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Quadriplegia, Spinal Cord Injury
Evaluation of a Tongue Operated Assistive Technology for Individuals With Severe Paralysis
This study was intended to evaluate a new assistive neuro-technology, known as the Tongue Drive System (TDS), by its potential end-users, i.e.
- Conditions
- Quadriplegia, Spinal Cord Injury, ALS
- Trial name
- TDS-1 (NCT01124292)
- Testing
- Tongue Piercing, Usability assessment
- Where
- 4 sites in United States
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Georgia Institute of Technology
Clinical Encounter Quality
Booster of the "More Time for Patients" Program
The goal of this clinical trial is to determine if reactivating a hospital program called "Plus de temps au service des patients" (PTP) can improve the quality of pain management for patients and increase job satisfaction among…
- Trial name
- NCT06491797
- Testing
- Immediate reactivation
- Where
- Switzerland
- Volunteers
- 764 people, healthy volunteers welcome
- Sponsor
- University Hospital, Geneva
Rheumatoid Arthritis
Anterior Shoulder US - a New Access
1. Investigate Gleno-Humeral Joint (GHJ) by anterior approach: A - Measurement of GHJ thickness at 3 points and average value calculation on body supine position and with arm supinated, maximal externally rotated with elbow angle…
- Trial name
- NCT01746966
- Where
- Israel
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Rambam Health Care Campus
Depression, Postpartum
Evaluation of Access to Screening for Post-partum Depression Via the Postnatal Interview Within 8 Weeks of Birth in Women Who Have Gave Birth at the Troyes Hospital ( DEPRESSIONPP )
Post-partum depression is defined as a depressive disorder with onset of symptoms in the year following childbirth. Several international studies have reported a prevalence of this condition of around pathology of around 15%.
- Trial name
- DEPRESSIONPP (NCT06469476)
- Testing
- depression post partum
- Where
- France
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier de Troyes
Chronic Diseases
Evaluating Community Health Centers' Adoption of a New Global Capitation Payment
The investigators are conducting a prospective analysis of the Alternative Payment Methodology (APM) demonstration project sites. The investigators' goal is to conduct a cross project analysis of findings.
- Trial name
- eCHANGE (NCT02637869)
- Testing
- Alternative Payment Model
- Volunteers
- 400,000 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
HIV, HIV Self-testing
Our Healthbox - Evaluating Interactive Dispensing Systems for Low-Barrier Access to HIV Testing and Harm Reduction.
When REACH Nexus at MAP Centre for Urban Solutions out of St. Michael's Hospital launched its signature program, I'm Ready in 2021, our goal was to democratize access to free HIV self-testing to reach the undiagnosed in Canada.
- Conditions
- HIV, HIV Self-testing, Harm Reduction, Sexually Transmitted Diseases
- Trial name
- NCT05516069
- Testing
- Our Healthbox (smart vending machine or interactive dispensing system)
- Where
- Canada
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- Unity Health Toronto
Drug Toxicity
Double-Blind Randomized Crossover Trial to Access Electrocardiogram Effects of HPN-100
Arm 1: Primary Objective: To determine the safety and tolerability of multiple ascending, supratherapeutic doses of HPN-100. Arm 2: Primary Objective: To assess the effects of steady-state levels of HPN-100 metabolites (4…
- Trial name
- NCT01135680
- Testing
- HPN-100, Moxifloxacin
- Where
- United States
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Amgen