Clinical trials: Access and Evaluation
End Stage Renal Disease
Adenovirus Vascular Endothelial Growth Factor (VEGF) Therapy in Vascular Access - Novel Trinam AGainst Control Evidence
Patients in renal failure on hemodialysis depend on adequate and sustained vascular access. This can be achieved by surgical placement of a synthetic polytetrafluoroethylene (PTFE) graft.
- Trial name
- AdV-VANTAGE (NCT00895479)
- Testing
- Graft placement surgery plus Trinam therapy
- Where
- 12 sites in United States
- Volunteers
- 250 people
- Sponsor
- Ark Therapeutics Ltd
Polycystic Kidney Disease, Assisted Reproductive Technology
Descriptive Analysis of Preimplantation Genetic Test (PGT)in Couples With Polycystic Kidney Disease (PKD). In the ADPKD Subgroup Evaluation of Outcomes and Complications Comparing Couples in Which the Father is Affected With Couples in Which the Mother is Affected
The goal of this observational study is to evaluate the outcomes of assisted reproductive technology (ART) combined with preimplantation genetic testing for monogenic diseases (PGT-M) in couples affected by or carriers of…
- Conditions
- Polycystic Kidney Disease, Assisted Reproductive Technology, Preimplantation Genetic Testing (PGT)
- Trial name
- PGT-M PKD (NCT07310641)
- Testing
- Assisted reproductive technology and preimplantation diagnosis for monogenic diseases
- Where
- Italy
- Volunteers
- 44 people
- Sponsor
- Azienda Sanitaria Universitaria Integrata del Trentino
Rheumatoid Arthritis
Anterior Shoulder US - a New Access
1. Investigate Gleno-Humeral Joint (GHJ) by anterior approach: A - Measurement of GHJ thickness at 3 points and average value calculation on body supine position and with arm supinated, maximal externally rotated with elbow angle…
- Trial name
- NCT01746966
- Where
- Israel
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Rambam Health Care Campus
Cardiac Arrest
Intraosseous vs Intravenous Access for Cardiac Arrest Treatment
In patients with out-of-hospital cardiac arrest in Singapore, investigators aim to assess the benefit of introducing a resuscitation protocol including the use of intravenous (IV) access and/or intraosseous (IO) vascular access…
- Trial name
- NCT02088736
- Testing
- Intraosseous, Intravenous
- Where
- Singapore
- Volunteers
- 1,103 people
- Sponsor
- Singapore General Hospital
Serious Mental Illness
Piloting and Evaluation of a Group Intervention for People With Psychosis Designed to Boost Access and Usage of ICT
Participants will be given access to a tablet. With this technology, participants will be invited to set personal goals related to using this technology to foster social connection and community participation.
- Trial name
- NCT07025499
- Testing
- Group ICT Intervention
- Where
- Canada
- Volunteers
- 18 people
- Sponsor
- McMaster University
Surgical Wound
The Closer Trial: A Safety and Efficacy Study of the Rex Medical Vascular Sealing System
The objective of this trial is to demonstrate the safety and effectiveness of the Rex Medical Closer Vascular Sealing System in sealing femoral arterial access sites.
- Trial name
- Closer (NCT02136004)
- Testing
- Closer VSS
- Where
- 12 sites in United States
- Volunteers
- 220 people
- Sponsor
- Rex Medical
Substance Use Disorders, Treatment Adherence and Compliance
Kentucky Access to Recovery Evaluation
Evaluate the long-term effectiveness of implementing vouchers as a linkage strategy in a population requiring recovery support services (RSS) when no other funding sources are available.
- Trial name
- NCT05889702
- Testing
- KATR Linkage Strategy
- Where
- 2 sites in United States
- Volunteers
- 458 people
- Sponsor
- Terry Bunn
Mental Disorders
Reducing Stigma Among Healthcare Providers to Improve Mental Health Services
A growing number of trials have demonstrated treatment effectiveness for people with mental illness (PWMI) by non-specialist providers, such as primary care and community health workers, in low-resource settings.
- Trial name
- RESHAPE-mh (NCT02793271)
- Testing
- RESHAPE, PRIME/mhGAP
- Where
- Nepal
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Brandon A Kohrt, MD, PhD
Age Related Macular Degeneration
Evaluation of TeleOphthalmology in AMD-TeleMedicine Solutions to Improve Patient Access and Quality of Vision Outcomes
Hypothesis: The use of teleophthalmology for patient screening will result in more rapid patient access for treatment. The use of teleophthalmology to monitor patients with wet AMD post-treatment will result in maintenance of…
- Trial name
- NCT01581606
- Where
- Canada
- Volunteers
- 169 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Egg Consumption
Enhancing Access to Safe and Nutritious Diets (ENSAND) Evaluation Nigeria
The Global Alliance for Improved Nutrition (GAIN) is implementing a program in 4 countries to increase consumption of healthy foods by improving supply, increasing demand, and improving the enabling environment for different…
- Trial name
- NCT05953753
- Testing
- Food system and demand generation
- Where
- Nigeria
- Volunteers
- 1,625 people, healthy volunteers welcome
- Sponsor
- RTI International
Arteriovenous Fistula, Pain
Evaluating the Effect of the Valsalva Maneuver on Invasive Pain During Arteriovenous Fistula Cannulation in Hemodialysis Patients
The goal of this clinical trial is to evaluate whether the Valsalva maneuver reduces invasive pain during arteriovenous fistula (AVF) cannulation in adult hemodialysis patients.
- Conditions
- Arteriovenous Fistula, Pain, Hemodialysis Access Failure, Vascular Access Device Complications
- Trial name
- VALPAIN-HD (NCT07066579)
- Testing
- Valsalva Maneuver
- Volunteers
- 60 people
- Sponsor
- Cansu POLAT DÜNYA
Solid Tumor, Peritoneal Metastasis
A Phase II Clinical Study to Evaluate the Efficacy and Safety of Technetium [99mtc]-H7ND Injection in the Diagnosis of Peritoneal Metastasis of Gastrointestinal Malignant Tumor.
The main purpose of this study is to evaluate the effectiveness of technetium [99mTc]-H7ND injection in the diagnosis of peritoneal metastasis of gastrointestinal malignant tumor.
- Trial name
- NCT07107633
- Testing
- Technetium [99mTc]-H7ND injection
- Where
- China
- Volunteers
- 90 people
- Sponsor
- Jiaxing Pharmadax Genesis Pharmaceutical Technology Co.,Ltd.
Health Care Quality, Access, and Evaluation, Smoking Cessation
PROS Smokebusters: Adolescent Smoking Cessation in Pediatric Primary Care
This is a pilot study addressing office systems and clinician behavior change surrounding smoking cessation interventions for teens.
- Trial name
- NCT00135265
- Testing
- smoking cessation, practice change
- Where
- United States
- Volunteers
- 4,100 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Multiple Sclerosis
Ocrelizumab Access by Socio-Economic Status
The primary aim of this project is to determine whether there are differences in access to, efficacy and tolerability of Ocrelizumab in men and women of different racial and ethnic origins and socio-economic backgrounds with RRMS…
- Trial name
- NCT05131984
- Testing
- Ocrelizumab
- Where
- United States
- Volunteers
- 800 people
- Sponsor
- Brigham and Women's Hospital
Urolithiasis
Measurement of Resistance During UAS Insertion Procedure in RIRS
Retrograde intrarenal surgery (RIRS) has been considered as the first-line choice for the management of <20mm kidney stones. Insertion of a ureteral access sheath (UAS) before RIRS surgery is currently accepted as an effective…
- Trial name
- NCT03919227
- Testing
- empty bladder before inserting UAS, do not interfere with the filling degree of bladder
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Guohua Zeng
Obesity, Obesity, Morbid
Trans-nasal Endoscopy for Bariatric Patients
This study plans to learn if the EvoEndo Endoscopy system can be used to evaluate, provide and follow up care for upper gastrointestinal tract diseases in the bariatric population.
- Conditions
- Obesity, Obesity, Morbid, Obese, GI Disorders
- Trial name
- TNE (NCT06200961)
- Testing
- Transnasal Endoscopy, Esophagogastroduodenoscopy
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Christopher C. Thompson, MD, MSc
Choledocholithiasis, Common Bile Duct Neoplasms
Prospective Multicenter Evaluation of a New Short-access-cholangioscope for Biliary Duct Strictures and Gall Stones
Karl Storz GmbH (Gesellschaft mit beschränkter Haftung) company developed a cholangioscopic device, which is designed to give a better flexibility to the cholangioscopy tip in order to enable optimal diagnostic and therapeutic…
- Conditions
- Choledocholithiasis, Common Bile Duct Neoplasms, Cholestasis
- Trial name
- SAC (NCT01683240)
- Testing
- cholangioscopy (Frimberger)
- Where
- 5 sites in Germany
- Volunteers
- 59 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Health Care Quality, Access, and Evaluation, Insurance, Health
Effectiveness of A Health Microinsurance Scheme for Private Primary Care in Malaysia
This is the Phase 3 of a 3 phase study to determine the feasibility, acceptability and effectiveness of a health microinsurance scheme in improving health equity and clinical outcomes for private primary care (PPC) in Kuala…
- Trial name
- HMI (NCT02696174)
- Testing
- HMI
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- Chulalongkorn University
Mental Disorder
Improving Access to Psychiatric Care for Patients in Primary Care
Getting a consultation with a psychiatrist within an appropriate time is one of the main issues reported by general practitioners (GP) for patients suffering from mental disorders in primary care.
- Trial name
- DSPP-PSY (NCT03508518)
- Testing
- Shared care device in psychiatry (DSPP), Usual Care
- Where
- France
- Volunteers
- 151 people
- Sponsor
- University Hospital, Toulouse
Arteriovenous Fistula Stenosis, Arteriovenous Fistula
A Prospective, Multi-center Study to Evaluate Efficacy and Safety of BSJ020R in Treatment of AVF for Hemodialysis (RANGER AV Japan Study)
A prospective, multi-center study to evaluate efficacy and safety of BSJ020R in treatment of AVF for hemodialysis
- Conditions
- Arteriovenous Fistula Stenosis, Arteriovenous Fistula, Vascular Access
- Trial name
- NCT06639451
- Testing
- RANGER™ Paclitaxel Coated Balloon Catheter
- Where
- 8 sites in Japan
- Volunteers
- 186 people
- Sponsor
- Boston Scientific Corporation