Clinical trials: Accident
Stroke, Ischemic Cerebrovascular Accident
Vagus Nerve Stimulation on Improving Sleep in Inpatient Rehab for Post-Acute Stroke
The goal of this clinical trial is to learn if a device which provides vagal nerve stimulation, applied to the tragus of the ear via an ear clip, can improve sleep in individuals recovering from stroke while they are treated in a…
- Conditions
- Stroke, Ischemic Cerebrovascular Accident, Ischemic Stroke, Vagal Nerve Stimulation
- Trial name
- NCT07858656
- Testing
- transauricular Vagal Nerve Stimulation
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- Casa Colina Hospital and Centers for Healthcare
Cerebrovascular Accident
Biomechanical and Neurophysiological Evaluation of the Effect of a Motor Block and an Injection of Botulinum Toxin on the Stiffness of the Paretic Sural Triceps Muscle
The research "Biomechanical and neurophysiological evaluation of the effects of a motor block and an injection of botulinum toxin on the stiffness of the paretic sural triceps muscle" will study the response to passive stretching…
- Trial name
- RAI PAR BLOC (NCT04717141)
- Testing
- Selective nerve block
- Where
- France
- Volunteers
- 27 people
- Sponsor
- Nantes University Hospital
Troponin T, Hemolysis
Effect of in Vitro Haemolysis on Serum High Sensitivity Troponin T Measurements From Patients in Accident & Emergency
This study will be investigating how a common blood test for identifying heart damage (Troponin T) is affected by red blood cell damage in the blood sample (Haemolysis).
- Trial name
- NCT03439605
- Where
- United Kingdom
- Volunteers
- 61 people
- Sponsor
- Poole Hospital NHS Foundation Trust
Anthracycline Extravasation
Efficacy of TopotectTM (Dexrazoxane) for Accidental Extravasation of Anthracyclines
The purpose of this study is to avoid surgical intervention following extravasation of anthracycline chemotherapy out of a vessel into the surrounding tissues.
- Trial name
- NCT00548561
- Testing
- Dexrazoxane
- Where
- 9 sites in Denmark
- Volunteers
- 23 people
- Sponsor
- Valerio Therapeutics
Healthy Aging, Exercise Therapy
Land vs. Water Exercises on Performance and Swimming Behavior in Older Adults
This study aims to investigate the effects of an 8-week combined land and aquatic exercise program (conducted 3 days per week) on physical performance, recreational swimming behaviors, and water-related risk perceptions in older…
- Conditions
- Healthy Aging, Exercise Therapy, Resistance Training, Hydrotherapy
- Trial name
- NCT07784205
- Testing
- 8-Week Beach and Aquatic Exercise Intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Eskisehir Technical University
Stroke, Cerebrovascular Accident
Comparing Constraint-Induced Therapy and Occupation-Based Intervention for Optimal Stroke Recovery
This pilot study was designed to compare the effects of modified constraint-Induced therapy and occupation-based intervention to increase functional motor recovery in stroke
- Trial name
- NCT02850042
- Testing
- Occupation-based practice (OBP), Modified-constraint induced therapy (m-CIT)
- Volunteers
- 16 people
- Sponsor
- Lumy Sawaki
Cerebrovascular Accident
A Study to Evaluate the Effects of YM872 on Stroke Lesion Volume in Acute Stroke Patients
This study will investigate the effects of a potential neuroprotectant compound, YM872, in the treatment of acute ischemic stroke.
- Trial name
- NCT00044070
- Testing
- YM872 (zonampanel)
- Where
- 89 sites in United States, Austria and 4 more
- Sponsor
- Astellas Pharma Inc
Poisoning, Safety Issues
Evaluating the Impact of a Safe Medication Storage Device
Despite the initial success of the 1970s Poison Prevention Packaging Act, the incidence of pediatric medication poisonings in the United States remains high.
- Conditions
- Poisoning, Safety Issues, Accidents Injury
- Trial name
- NCT04729894
- Testing
- Medication Lockbox, Education
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Binghamton University
Trauma Injury
Reducing Low-value Care for Trauma Admissions
In Canada, injury leads to more potential years of life lost and to greater costs than heart and stroke diseases combined. Furthermore, more than 50% of patients hospitalised following injury do not receive optimal care, 20% of…
- Trial name
- NCT05744154
- Testing
- Audit & feedback with educational outreach and facilitation, Simple audit & feedback (usual practice)
- Where
- Canada
- Volunteers
- 29 people
- Sponsor
- Laval University
Cardiac Death, Hemorrhage
Efficacy and Safety of BiomatrixTM Stent and 5mg-Maintenance Dose of Prasugrel in Patients With Acute Coronary Syndrome
The purpose of this study is to evaluate the efficacy and safety of 5mg maintenance dose (MD) of prasugrel in patients with acute myocardial infarction (AMI) who underwent percutaneous coronary intervention (PCI) with BiomatrixTM…
- Conditions
- Cardiac Death, Hemorrhage, Cerebrovascular Accident, Myocardial Infarction
- Trial name
- BEAUTY-II (NCT02446730)
- Testing
- BES (biodegradable polymer biolimus-eluting stent), Prasugel, Clopidogrel
- Where
- South Korea
- Volunteers
- 1,400 people, healthy volunteers welcome
- Sponsor
- Chonnam National University Hospital
Trauma/Injury Problem
Pre and Post-Implementation of Injury/Trauma First Aid Training Among Early Secondary School Students in Fako, Cameroon
To save lives, alleviate pain, and prevent injuries from worsening before medical assistance can be summoned, first aid is essential. These fundamental skills are accessible to everyone, including young people.
- Trial name
- NCT07110077
- Testing
- Young First Aiders Traing of Early Secondry School children
- Where
- Cameroon
- Volunteers
- 166 people, healthy volunteers welcome
- Sponsor
- University of Buea
Stroke, Aphasia
Electro-physiological Signs to Prognostic Aphasia Recovery After a Stroke
The purpose of this study is to study, among the aphasic person, if motor function ( studied by Motor Evoked Potentials) performed within the first 14 days after a stroke can predict a good recovery from aphasia 6 months of the…
- Trial name
- APHA-TMS (NCT03103230)
- Testing
- Cortical magnetic stimulation
- Where
- France
- Volunteers
- 130 people
- Sponsor
- University Hospital, Bordeaux
Ischemic Stroke, Acute, Dysphagia Following Cerebrovascular Accident
Dysphagia After Transesophageal Echocardiography in Acute Stroke - Follow Up Trial
The aim of the prospective observational TEDRAS - Follow-up Trial is to investigate the limitations of the initial TEDRAS - Trial in patients with acute Dysphagia is a common consequence from ischemic stroke and it correlates…
- Trial name
- TEDRAS2 (NCT06195501)
- Testing
- Flexible Endoscopic Evaluation of Swallowing (FEES) ; Transesophageal Ecocardiography (TEE)
- Where
- Germany
- Volunteers
- 40 people
- Sponsor
- University of Giessen
Spasticity, Cerebrovascular Accident
Efficacy and Safety Study of MYOBLOC® in the Treatment of Adult Upper Limb Spasticity
Phase 2/3, randomized, double-blind, placebo-controlled, single-treatment, multicenter trial assessing the efficacy and safety of MYOBLOC for the treatment of upper limb spasticity in adults followed by an open-label extension…
- Conditions
- Spasticity, Cerebrovascular Accident, Multiple Sclerosis, Traumatic Brain Injury
- Trial name
- NCT04815967
- Testing
- Phase 2; Low Dose MYOBLOC (10,000 Units), Phase 2; High Dose MYOBLOC (20,000 Units), Phase 3; MYOBLOC
- Where
- 9 sites in United States, Hungary and 1 more
- Volunteers
- 32 people
- Sponsor
- Solstice Neurosciences, LLC, a subsidiary of MDD US Operations, LLC
Bone Density, Muscles
Effects of Whole Body Vibration in Different Devices on Bone and Muscle Mass in Postmenopausal Women
Postmenopausal women suffer from a series of negative health factors, such as decreased bone and muscle mass and physical performance, increasing the risk of falls and decreasing quality of life.
- Conditions
- Bone Density, Muscles, Physical Functional Performance, Accidental Falls
- Trial name
- NCT06222931
- Testing
- Triplanar vibrating platform, Side-alternating vibrating platform
- Where
- Brazil
- Volunteers
- 127 people, healthy volunteers welcome
- Sponsor
- Universidade Estadual do Norte do Parana
Helmet Use, Cyclists
The Effect of Visual Patient Education on Helmet Use Behaviour in Elderly Patients After a Bicycle, E-bike, or Moped Accident
This is a multicenter randomized controlled trial (RCT) targeting individuals aged 60 and older who present to the emergency department following an accident.
- Conditions
- Helmet Use, Cyclists, Video Information
- Trial name
- HelmED RCT (NCT07773545)
- Testing
- Educational video
- Where
- 3 sites in Netherlands
- Volunteers
- 228 people, healthy volunteers welcome
- Sponsor
- Erasmus Medical Center
Alzheimer Disease, CVA (Cerebrovascular Accident)
Open Label Trial of Rivastigmine Patch in Subjects With Mild to Moderate Stage AD Having Coexisting svCVD
Rivastigmine, an acetylcholinesterase inhibitor which has been approved by FDA \& HSA, is authorized for use in the treatment of mild to moderate dementia of the Alzheimer's type.
- Trial name
- NCT02444637
- Testing
- Rivastigmine
- Where
- Singapore
- Volunteers
- 100 people
- Sponsor
- National Neuroscience Institute
Accidents, Traffic
Improving Motorcycle Taxi Driver Visibility in Tanzania
The purpose of this study is to determine whether providing motorcycle taxi drivers with a free reflective fluorescent vest will result in increased use of reflective or fluorescent clothing compared to education about wearing…
- Trial name
- NCT01733537
- Testing
- Free reflective, fluorescent vest, Education
- Where
- Tanzania
- Volunteers
- 180 people
- Sponsor
- Duke University
Trauma Injury
A Nursing Triage Protocol for Minor Orthopedic Traumata: the Effect on Flow Time, Quality of Care and Patient Satisfaction in an Emergency Department
In 2019, nearly half of all hospital contacts in Belgium took place through the emergency department, and more than a third of patients arrived after an accident or trauma.
- Trial name
- TRINU-RX (NCT05765045)
- Testing
- Nursing triage protocol
- Where
- Belgium
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Universiteit Antwerpen
Accidental Fall
Reactive Balance Training Targeting Both Slip- and Trip-Induced Falls
The goal of this study was to evaluate the effects of reactive balance training (RBT) targeting slipping and tripping on laboratory-induced slips and trips.
- Trial name
- NCT04308239
- Testing
- Reactive balance training, Otago Balance Training
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Virginia Polytechnic Institute and State University
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