Clinical trials: Accommodation Disorder
Heart Failure
Influence of Edoxaban on Coagulability and Thrombin Generation: An in Vitro Study Focusing on Thrombelastography
The influence of different doses of edoxaban on physical characteristics of the clot and thrombin generation kinetics in blood samples will be studied by in vitro spiking of blood samples collected from patients treated for heart…
- Trial name
- NCT02448901
- Testing
- Edoxaban
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- LifeBridge Health
Father-Child Relations
Run Daddy Run! A Lifestyle Intervention Focusing on Fathers and Their Children
The aim of this study is to develop and implement a multicomponent eHealth lifestyle intervention (focusing on (co-) physical activity and screen time) for fathers and their children, aiming to prevent childhood overweight and…
- Trial name
- RDR (NCT04590755)
- Testing
- Interactive father-child sessions and website
- Where
- Belgium
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- University Ghent
Cardiovascular Diseases, Metabolic Syndrome
Non-interventional Pre-screening Protocol Aims to Evaluate Participants for Potential Trial Eligibility in Future Clinical Trials/Studies Focusing on Metabolic and Psychiatric Health.
DOVE-MET-COME-100 is a single site prescreening survey study designed to identify adults who may be eligible for future industry-sponsored clinical trials.
- Conditions
- Cardiovascular Diseases, Metabolic Syndrome, Obesity, Prediabetes
- Trial name
- NCT07106879
- Testing
- Blood Work
- Where
- United States
- Volunteers
- 7,000 people, healthy volunteers welcome
- Sponsor
- Clindove Research LLC
Work Disability Reduction and Prevention, Improving Return-to-Work Outcomes
SMART Supervisor Training Program to Prevent Work Disability
Supervisors of injured workers play a key role in preventing prolonged work absences. Providing supervisors with tools to improve their response to musculoskeletal and other workplace injuries or illnesses may improve worker…
- Trial name
- NCT02309996
- Testing
- Supervisor Training Program
- Where
- Canada
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- Lakehead University
Binocular Vision Disorder
Binocular Vision Alternations and fMRI Activation After ICL Implantation for High Myopia
Implantable collamer lens (ICL) is one of the most effective operation for high myopia. Due to refractive correction changed, and prism effect of the spectacle removed, in the early stage after ICL implantation, binocular…
- Trial name
- NCT05633212
- Where
- China
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen University
Glaucoma, Ocular Hypertension
Association Between Limbal Function and Tear Proteomics in Chronic Ocular Diseases: Focusing on Glaucoma
Background Intact corneal epithelium is important for the defense on the ocular surface, and the function of limbal stem cells is crucial to maintain its integrity.
- Conditions
- Glaucoma, Ocular Hypertension, Limbal Stem Cell Deficiency
- Trial name
- NCT07119580
- Where
- Taiwan
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Glaucoma, Myopia
Morphological Changes of Ciliary Body and Trabecular Meshwork
Glaucoma is the leading cause of irreversible blindness worldwide. Although the pathogenesis remains unclear, pathologic increase in intraocular pressure (IOP) due to blocked aqueous outflow through the trabecular-Schlemm canal…
- Trial name
- NCT05352854
- Testing
- 0.5% pilocarpine eye drops
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Yune Zhao
Severe Mental Disorder, Severe Mental Illness
Real-time Experiences, Physical Activity and Biological Outcomes in Personal Recovery Residents (EMPOWER-RES)
The project focuses on patients with severe mental disorders (SMD) residing in Italian mental health supported accommodation (SA).
- Trial name
- EMPOWER-RES (NCT06914622)
- Testing
- Mental Health Recovery Star (MHRS)
- Where
- 3 sites in Italy
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- IRCCS Centro San Giovanni di Dio Fatebenefratelli
Hyperopia
Enhancement of Emmetropization in Highly Hyperopic Infants
Infants do not usually wear glasses because they usually do not need them to see clearly. Most infants are born with a moderate amount of farsightedness.
- Trial name
- NCT03669146
- Testing
- Glasses
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Donald O Mutti, OD, PhD
Metabolic Syndrome, Type 2 Diabetes
Lifestyle Intervention for Pakistani Women in Oslo
Immigrants from South Asia in Norway have a high prevalence of type 2 diabetes and conditions related to the metabolic syndrome. It has been documented that these conditions may be prevented by changes in lifestyle.
- Trial name
- InnvaDiab (NCT00425269)
- Testing
- lifestyle intervention (diet and physical activity)
- Where
- Norway
- Volunteers
- 198 people, healthy volunteers welcome
- Sponsor
- University of Oslo
Anxiety Disorders
Empowering Anxious Parents to Manage Child Avoidance Behaviors
Efforts to develop and disseminate evidence based practices (EBPs) for youth anxiety have made great strides. Still, up to 82.2% of youth who need mental health treatment for anxiety never access care or drop out prematurely…
- Trial name
- EMPOWER (NCT04453865)
- Testing
- Project EMPOWER, Online Resources and Referrals
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Stony Brook University
Distance Viewing, Prolonged Near Viewing
Measuring How Quickly the Eye Focuses After Sustained Viewing of Close-up Images and Videos
In this experiment, subjects will view a cross pattern on the screen and be asked to focus their eyes on it. The cross pattern will look like it is moving towards and away from the eye in a back-and-forth motion.
- Trial name
- NCT07679048
- Testing
- Near viewing first, Distant viewing first
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Rochester Institute of Technology
Myopia
The Effects of Low Concentration Atropine on Pupil Size and Accommodation
The purpose of this study is to determine whether less frequent dosing of atropine drops may be as effective as daily dosing for the treatment of progressive myopia.
- Trial name
- NCT02870478
- Testing
- Atropine
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of California, Berkeley
Presbyopia
Safety and Effectiveness Study of the AcuFocus Corneal Inlay ACI 7000PDT in Presbyopes
The purpose of this study is to determine if the AcuFocus Corneal Inlay ACI 7000PDT will provide an effective method for the correction of presbyopia in patients who have normal distance vision but need a correction such as…
- Trial name
- ACI (NCT00850031)
- Testing
- AcuFocus Corneal Inlay
- Where
- 8 sites in Australia, Austria and 4 more
- Volunteers
- 119 people, healthy volunteers welcome
- Sponsor
- AcuFocus, Inc.
Myopia, Accommodation
Dynamic Change in Accommodation After Wearing Multifocal Soft Contact Lenses for Myopia Control
The purpose of this study is to report the changes in accommodation, aberrations, and myopia in patients wearing multifocal soft contact lens for various durations. The study objectives are to: 1.
- Trial name
- NCT04763694
- Testing
- Multifocal soft contact lenses
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- State University of New York College of Optometry