Clinical trials: Accuracy of Tissue Diagnosis
Potentially Malignant Lesions, Oral Lichen Planus
Diagnostic Accuracy of lncRNA DQ786243 and miRNA146a in Saliva of Oral Potentially Malignant Lesions
The aim of this study is to evaluate salivary expression of lncRNA DQ786243 as a potential marker for diagnosis of oral potentially malignant lesions compared to normal controls and its effect on salivary expression of miRNA146a.
- Conditions
- Potentially Malignant Lesions, Oral Lichen Planus, Leukoplakia, Oral
- Trial name
- NCT05730855
- Testing
- Real-time Polymerase Chain Reaction technique
- Where
- Egypt
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Fayoum University
Ductal Carcinoma In Situ, Invasive Breast Cancer
Digital Breast Tomosynthesis Versus Contrast Enhanced Magnetic Resonance Imaging (MRI) for Breast Cancer Staging
The primary objective of this study is to compare the diagnostic accuracy of Digital Breast Tomosynthesis (DBT) versus that of Contrast Enhanced Magnetic Resonance Imaging (CEMRI) in determining the size of breast cancer…
- Trial name
- NCT01060085
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Cellulitis, Skin and Subcutaneous Tissue Infection
Utility of Thermal Imaging in Diagnosis of Cellulitis for Lower Extremity Complaints in the Emergency Department
The overall purpose of the study is to determine how providing physicians with a quantitative measure of skin surface temperature influences diagnoses and diagnostic confidence in potential cellulitis cases when added to the…
- Trial name
- NCT04928235
- Testing
- Thermal Imaging as Diagnostic Adjunct
- Where
- United States
- Volunteers
- 416 people
- Sponsor
- University of Wisconsin, Madison
Phyllodes Breast Tumor, Artificial Intelligence
AI-Assisted System for Accurate Diagnosis and Prognosis of Breast Phyllodes Tumors
Breast phyllodes tumor (PT) is a rare fibroepithelial tumor, accounting for 1% to 3% of all breast tumors, categorized by the WHO into benign, borderline, and malignant, based on histopathology features such as tumor border…
- Conditions
- Phyllodes Breast Tumor, Artificial Intelligence, Multiomics, Prognostic Cancer Model
- Trial name
- NCT06286267
- Testing
- imaging
- Where
- 4 sites in China
- Volunteers
- 4,000 people
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Soft Tissue Sarcoma, Osteosarcoma
Huntsman Biopsy Study
Bone and soft tissue sarcomas are currently classified based upon light microscopy supplemented by immunohistochemistry, but within many if not all of these tumor histologic types, considerable heterogeneity exists not only in…
- Trial name
- NCT00615329
- Where
- United States
- Volunteers
- 142 people
- Sponsor
- State University of New York - Upstate Medical University
Breast Cancer
Evaluate The Accuracy Of Breast MRI Biopsy In Diagnosing A Complete Tumor Response For Some Women Following Neoadjuvant Chemotherapy For Breast Cancer
The purpose of this study is to test the ability of a breast MRI biopsy to accurately diagnose a complete tumor response to the neoadjuvant chemotherapy (NAC) that the patient just finished.
- Trial name
- NCT03289195
- Testing
- MRI Biopsy
- Where
- 7 sites in United States
- Volunteers
- 31 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Diabetic Foot
Validation of Ipswich Touch Test for Diabetic Peripheral Neuropathy Screening in Primary Care
The goal of this observational study is to assess the accuracy of screening for diabetic peripheral neuropathy by comparing the Ipswich touch test with the 10-g monofilament test in patients diagnosed with type 2 diabetes.
- Trial name
- NCT06288555
- Testing
- Ipswich touch test
- Where
- Thailand
- Volunteers
- 274 people, healthy volunteers welcome
- Sponsor
- Ponlawat Hanchana, MD
Foot Ulcer, Foot Ulcer, Diabetic
Diabetic Foot Ulcer Imaging- Study 2
All study procedures will occur during one appointment. The research team will measure the size of the foot ulcer (if one is present) and multiple photos will be taken with a smart phone camera and thermal camera.
- Trial name
- NCT03942081
- Testing
- Ulcer Measurement Software
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- Linnea Polgreen
Diabetes Mellitus
Assessing Continuous Glucose Monitors in Healthy Children
Continuous glucose monitors may be useful in the treatment of children with Type 1 diabetes mellitus. The purpose of this study was to determine whether two FDA-approved continuous glucose monitors, the Continuous Glucose…
- Trial name
- NCT00069602
- Testing
- Continuous Glucose Monitoring System (CGMS), GlucoWatch G2TM Biographer (GW2B)
- Where
- 6 sites in United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Jaeb Center for Health Research
Meningioma
Concordance and Accuracy of MRI in the Detection of Meningiomas: Optimizing Sequences With Low Doses of Gadolinium
Meningioma, an extra-axial brain tumor developed at the expense of meninges, accounts for 35% of central nervous system tumors, and its incidence is estimated at 3% in large autopsy series.
- Trial name
- CAMOMILLE (NCT04113395)
- Testing
- sequences T1 FE
- Where
- 10 sites in France
- Volunteers
- 514 people
- Sponsor
- Fondation Ophtalmologique Adolphe de Rothschild
Skin and Connective Tissue Diseases, Neglected Tropical Diseases
Early Detection and AI-Based Management of Skin-Related Neglected Tropical Diseases in Sub-Saharan Africa by Frontline Health Workers
Skin-related Neglected Tropical Diseases (Skin NTDs) affect about 1.8 billion people worldwide, particularly in poor and rural communities where healthcare access is limited.
- Conditions
- Skin and Connective Tissue Diseases, Neglected Tropical Diseases, Leprosy, Buruli Ulcer
- Trial name
- SkincAIr (NCT07506967)
- Testing
- A mobile app with AI functionality for diagnosing skin-related NTDs
- Where
- 5 sites in Democratic Republic of the Congo, Ethiopia and 3 more
- Volunteers
- 2,420 people
- Sponsor
- Kenya Medical Research Institute
Low Blood Pressure, Normal Blood Pressure
Clinical Trial of H2-BP Electronic Sphygmomanometer
The study compares H2-BP, a wristband blood pressure monitor, with an auscultatory sphygmomanometer. Both devices are used on the same arm.
- Conditions
- Low Blood Pressure, Normal Blood Pressure, Prehypertension, Hypertension
- Trial name
- NCT06491433
- Testing
- H2-BP
- Where
- South Korea
- Volunteers
- 141 people, healthy volunteers welcome
- Sponsor
- Gangnam Severance Hospital
Gastrointestinal Stromal Tumors
Laparoscopic Resection of Large Gastric Stromal Tumors
Despite laparoscopic surgical treatment has not been recommended in patients with gastric gastrointestinal stromal tumors (GIST) larger than 5 centimeter, but it continues to evolve rapidly to overcome the boundaries.
- Trial name
- NCT02662478
- Testing
- Laparoscopic Surgery
- Volunteers
- 23 people
- Sponsor
- Medical Park Gaziantep Hospital
Pressure Ulcers, Pressure Injuries
Research and Application Evaluation of Accurate Pressure Ulcer Area Measurement Technology Based on AI Grid Intelligent Recognition: A Self-controlled Study
The goal of this clinical trial is to learn if AI grid image recognition can measure pressure ulcer wound area accurately and efficiently in adult patients with pressure ulcers.
- Trial name
- NCT07743385
- Testing
- AI Grid Image Recognition Measurement, Traditional Manual Grid Counting Measurement
- Where
- 3 sites in China
- Volunteers
- 100 people
- Sponsor
- Affiliated Hospital of Nantong University
Neuroblastoma, Medulloblastoma
Accurate Diagnosis and Grading of Pediatric Solid Tumors Based on Pathological Large Models
Pediatric malignancies are the second leading cause of death in the pediatric population, with solid tumors accounting for approximately 60% of all pediatric malignancies.
- Conditions
- Neuroblastoma, Medulloblastoma, Wilms Tumor, Hepatoblastoma
- Trial name
- NCT06822842
- Where
- China
- Volunteers
- 1,229 people
- Sponsor
- Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
Spinal Tumor
A Prospective Study Using Implanted Fiducial Markers to Assess Treatment Accuracy and Esophageal Toxicity in Spinal Stereotactic Body Radiation Therapy
The goal of the first part of this clinical research study is to learn how to deliver more accurate radiation treatment of tumors in the spine.
- Trial name
- NCT01624220
- Testing
- Spinal SBRT (Standard Dose), Spinal SBRT (Higher Dose), Gold Seed Implantation
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- M.D. Anderson Cancer Center
Cutaneous Melanoma
MelaMEd Online Training for General Practitioners to Improve Melanoma Detection and Management
The goal of this trial was to learn whether the MelaMEd online training program could improve doctors' skills in the early detection and management of melanoma, the most aggressive type of skin cancer.
- Trial name
- MelaMEd (NCT07757386)
- Testing
- MelaMEd Online Training Program
- Where
- 10 sites in Italy
- Volunteers
- 1,531 people, healthy volunteers welcome
- Sponsor
- Istituto Romagnolo per lo Studio dei Tumori Dino Amadori IRST S.r.l. IRCCS