Clinical trials: Achilles Tendinopathy
Haglund Syndrome, Insertional Achilles Tendinopathy
Open Versus Fully Endoscopic Calcaneoplasty With Achilles Tendon Insertional Reconstruction for Haglund Syndrome
This project intends to retrospectively review the medical records of patients with Haglund's syndrome who underwent surgical treatment in the Department of Sports Medicine and Joint Surgery between 2019 and 2026, to analyze the…
- Trial name
- NCT07887165
- Where
- China
- Volunteers
- 67 people
- Sponsor
- Nanjing First Hospital, Nanjing Medical University
Achilles Insertional Tendinopathy, Achilles Tendinopathy
Single-Row Versus Double-Row Repair for Achilles Insertional Tendinopathy
Achilles insertional tendinopathy may require surgical debridement and tendon reattachment when non-operative treatment fails. Single-row and double-row repairs are used, with biomechanical studies favoring double-row, but…
- Trial name
- STRIDE (NCT07323875)
- Testing
- Single-row repair of the Achilles tendon at its calcaneal insertion, Double-row repair of the Achilles tendon at its calcaneal insertion
- Where
- Canada
- Volunteers
- 166 people
- Sponsor
- Women's College Hospital
Tendinopathy, Musculoskeletal Diseases or Conditions
Human Tendon Tissue Collection
The goal of this study is to improve understanding of tendon health and disease by using surplus tendon tissue that is routinely removed during planned orthopaedic surgeries in adults.
- Conditions
- Tendinopathy, Musculoskeletal Diseases or Conditions, ACL Surgery, Achilles Tendon Surgery
- Trial name
- NCT07606092
- Where
- 2 sites in United Kingdom
- Volunteers
- 400 people
- Sponsor
- Queen Mary University of London
Achilles Injuries Tendon, Achilles Tendinopathy (AT)
Extracorporeal Shockwave Therapy and Platelet-Rich Plasma for Midportion Achilles Tendinopathy
Midportion Achilles tendinopathy is a common cause of pain and functional limitation in both athletes and the general population.
- Conditions
- Achilles Injuries Tendon, Achilles Tendinopathy (AT), Achilles Tendinitis, Left Leg, Achilles Tendinitis, Right Leg
- Trial name
- NCT07483320
- Testing
- Platelet Rich Plasma, Extracorporeal Shockwave Therapy
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Spaulding Rehabilitation Hospital
Tendinopathy, Insertional Achilles Tendinopathy
Evaluation of Collagen-based Medical Device Treatment Combined With Physiotherapy in Subjects With Achilles Tendinopathy.
Achilles tendinopathy is a condition characterized by inflammation of the Achilles tendon. Achilles tendinopathies are classified into insertional tendinitis and noninsertional tendinitis.
- Conditions
- Tendinopathy, Insertional Achilles Tendinopathy, Achilles Tendinopathy, Peritendinitis
- Trial name
- AKITENMED (NCT05464498)
- Testing
- MD-Tissue Collagen Medical Device, eccentric strengthening protocol
- Where
- Italy
- Volunteers
- 72 people
- Sponsor
- Guna S.p.a
Achilles Tendinopathy
A Study to Investigate the Safety, Tolerability and Preliminary Efficacy of NGI226 Microparticles in Patients With Achilles Tendinopathy
The purpose of this study is to measure local and systemic safety and tolerability as well as improvement of Achilles tendon mechanical properties after a single peritendon injection of NGI226 MP in comparison to placebo MP in…
- Trial name
- NCT05592990
- Testing
- NGI226
- Where
- 7 sites in United States, France and 1 more
- Volunteers
- 45 people
- Sponsor
- Novartis Pharmaceuticals
Tendinopathy, Chronic Pain
Managing Chronic Tendon Pain by Metformin
The purpose of the current exploratory clinical trial is to determine the effect of oral ingestion of metformin (OIM) in non-diabetic patients with chronic Achilles tendon pain.
- Conditions
- Tendinopathy, Chronic Pain, Achilles Tendinopathy
- Trial name
- NCT06100822
- Testing
- Metformin
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- James Wang
Achilles Tendinopathy (AT)
Lower-Extremity Kinetic Chain Exercise Program for Achilles Tendinopathy
Achilles tendinopathy is a common condition that causes pain, stiffness, and reduced function of the Achilles tendon. It can affect both physically active individuals and the general adult population, often making everyday…
- Trial name
- LEKC-AT (NCT07730866)
- Testing
- Lower-Extremity Kinetic Chain Exercise Program, Conventional Exercise Program
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- May University in Cairo
Tendinopathy, Enthesopathy
Hyaluronic Acid Versus Platelet-Rich Plasma for Chronic Tendinopathy and Enthesopathy
Chronic tendinopathies and enthesopathies are common musculoskeletal conditions in orthopedics and sports medicine, frequently leading to pain, impaired function, and significantly reduced quality of life.
- Conditions
- Tendinopathy, Enthesopathy, Achilles Tendinopathy, Golfer's Elbow
- Trial name
- NCT07714811
- Testing
- Hyaluronic acid injection, Autologous Platelet-Rich Plasma Injection
- Where
- Poland
- Volunteers
- 80 people
- Sponsor
- Ortonika Orthopedic Medical Clinic in Lublin
Achilles Tendinopathy (AT)
Augmenting Standard Rehabilitation With Blood Flow Restriction for Chronic Achilles Tendinopathy
Chronic insertional Achilles tendinopathy is a common overuse condition that can be slow to improve with traditional loading-based rehab (e.g., eccentric loading, activity modification, graded return to function).
- Trial name
- NCT07699497
- Testing
- Standard-of-Care Rehabilitation Program for Chronic Insertional Achilles Tendinopathy, Blood Flow Restriction (BFR) Training Device
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Assiut University
Running-related Injuries, Medial Tibial Stress Syndrome
Machine Learning-Based Risk Identification and Precision Exercise for Common Running Injuries
This study aims to identify biomechanical risk factors associated with common running-related injuries in recreational runners using machine learning analysis.
- Conditions
- Running-related Injuries, Medial Tibial Stress Syndrome, Patellofemoral Pain, PFP, Chronic Achilles Tendinopathy
- Trial name
- NCT07689916
- Testing
- Multidimensional Precision Intervention, Precision Exercise Intervention
- Where
- China
- Volunteers
- 204 people
- Sponsor
- Zeyi Zhang
Achilles Tendinopathy (AT), Achilles Tendon
Achilles Tendinopathy; the Effect of Shockwave Treatment
BACKGROUND Achilles tendinopathy-pain in the Achilles tendon-is a common and often long-lasting condition that limits physical activity and performance, and also affects work capacity and quality of life.
- Conditions
- Achilles Tendinopathy (AT), Achilles Tendon, Achilles Tendon Pain
- Trial name
- NCT07685509
- Testing
- individually tailored exercises and Radial Shockwave, Individually tailored exercises
- Volunteers
- 200 people
- Sponsor
- Vastra Gotaland Region
Plantar Fasciopathy, Achilles Tendinopathy
QUANTIFY: Quantitative Understanding of Advanced Novel Techniques for Imaging Fasciitis and Yielding Biomarkers
This study is to create a test that can accurately find and measure the problem areas in muscle and fascia tissue, also known as myofascial pain.
- Conditions
- Plantar Fasciopathy, Achilles Tendinopathy, Controls
- Trial name
- QUANTIFY (NCT06803056)
- Testing
- Clinical exam, Ultrasound imaging, Magnetic Resonance Imaging
- Where
- United States
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- Ruth Chimenti
Achilles Tendinopathy (AT)
The ASPIRE Trial: AchilleS tendinoPathy Treated With cortIcosteRoid injEctions
Achilles tendinopathy is a common and often persistent tendon disorder associated with pain, impaired function, and reduced participation in physical activities.
- Trial name
- ASPIRE (NCT07650396)
- Testing
- Standard care, Depo-Medrol (methylprednisolone acetate 40 mg) combined with lidocaine
- Where
- Netherlands
- Volunteers
- 276 people
- Sponsor
- Erasmus Medical Center
Non-Insertional Achilles Tendinopathy
Dry Needling and Exercise for Mid-portion Achilles Tendinopathy
The purpose of this study is to determine if adding ultrasound-guided tendon dry needling with mechanical needle stimulation to a standard heavy, slow resistance (HSR) exercise program improves outcomes for individuals with…
- Trial name
- NCT07642583
- Testing
- Dry needling
- Where
- United States
- Volunteers
- 74 people
- Sponsor
- Brooke Army Medical Center
Achilles Tendinopathy (AT)
Effect of Foot Position During Rehabilitation of Achilles Tendinopathy on Tendon Mechanics and Symptoms.
This study will investigate whether a 12-week load-based exercise program performed with an externally rotated foot position ("toes-out") leads to different changes in intra-tendinous sliding, symptoms, and function compared to a…
- Trial name
- NCT07623408
- Testing
- 12-week adaptive, load-based exercise therapy protocol for Achilles Tendinopathy
- Where
- Belgium
- Volunteers
- 60 people
- Sponsor
- KU Leuven
Tendon Tear, Tendinopathy
Eendoscopic Versus Open Flexor Hallucis Longus Transfer in Managing Various Tendon Achilles Disorders
A well-established protocol for the treatment or augmentation a wide range of Achilles disorders including chronic Achilles tendon (AT) rupture, Achilles insertional tendinopathy, Haglund syndrome and among others, is a Flexor…
- Conditions
- Tendon Tear, Tendinopathy, Achilles Tendon Ruptures, Achilles Injuries Tendon
- Trial name
- NCT06639308
- Testing
- Endoscopic Flexor Hallucis longus tendon transfer to tendon achilles, Open Flexor Hallucis longus transfer to tendon achilles
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Assiut University
Achilles Tendinopathy, Eccentric Exercise
Pilates Method in Achilles Tendinopathy Rehabilitation
Achilles Tendinopathy (AT) is characterized by pain, swelling and dysfunction. Rehabilitation strategies focus on conservative treatment, with eccentric exercise being the main and most popular option.
- Conditions
- Achilles Tendinopathy, Eccentric Exercise, Pilates Method, Pilates Exercise
- Trial name
- NCT07039643
- Testing
- Pilates exercise, Alfredson protocol
- Where
- Greece
- Volunteers
- 49 people
- Sponsor
- University of West Attica
Achilles Tendinopathy
Does Resistance Training Protocol Change Micromorphology in Achilles Tendinopathy?
This work is designed as a prospective cohort study, in which the effects of a protocol of 12-week resistance training loading the Achilles tendon in patients with Achilles tendinopathy (AT) will be monitored.
- Trial name
- NCT06009536
- Testing
- Achilles Tendon Loading Exercise Protocol According to Silbernagel
- Where
- Czechia
- Volunteers
- healthy volunteers welcome
- Sponsor
- University Hospital, Motol
Patellar Tendinopathy, Achilles Tendinopathy (AT)
Evaluation of Platelet-Rich Plasma (PRP) Treatment in Tendinopathies
This multicenter, prospective, observational study, based on real-world evidence (RWE), aims to evaluate the efficacy and safety of Platelet-Rich Plasma (PRP) treatment across four types of tendinopathies: patellar, Achilles…
- Conditions
- Patellar Tendinopathy, Achilles Tendinopathy (AT), Epicondylitis, Lateral, Plantar Fasciitis, Chronic
- Trial name
- RWE-TDP-PRP (NCT07558564)
- Testing
- Platelet rich plasma (PRP)
- Where
- 5 sites in Spain
- Volunteers
- 2,000 people
- Sponsor
- ReSport Clinic