Clinical trials: Achilles Tendinopathy
Achilles Tendinopathy, Chronic Pain
Achillestendinopathy Treated With Proximal Medial Gastrocnemius Recession
This is a prospective cohort study that will follow 60 patients treated with Proximal Medial Gastrocnemius Recession for Chronic Mid-Portion Achilles Tendinopathy for 5 years postoperatively.
- Trial name
- NCT05179551
- Testing
- Proximal Medial Gastrocnemius Recession
- Where
- 2 sites in Norway
- Volunteers
- 60 people
- Sponsor
- Ostfold Hospital Trust
Achilles Tendinopathy (AT)
Lower-Extremity Kinetic Chain Exercise Program for Achilles Tendinopathy
Achilles tendinopathy is a common condition that causes pain, stiffness, and reduced function of the Achilles tendon. It can affect both physically active individuals and the general adult population, often making everyday…
- Trial name
- LEKC-AT (NCT07730866)
- Testing
- Lower-Extremity Kinetic Chain Exercise Program, Conventional Exercise Program
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- May University in Cairo
Tendinosis, Tendinopathy
Safety and Efficacy of RCT-01 in Men and Women With Unilateral, Chronic Achilles Tendinosis
The primary purpose of this study is to assess the safety profile of RCT-01 injections as compared to placebo injections. This study will also measure the impact these injections will have on tendon structure and function and the…
- Trial name
- ReaCT (NCT02330146)
- Testing
- RCT-01
- Where
- Canada
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- RepliCel Life Sciences, Inc.
Tendinopathy
Effectiveness of Isometric vs. Eccentric Exercise in Chronic Achilles Tendinopathy
This is a prospective single blinded randomised controlled trial with a 12-week intervention period and a half-year follow-up period.
- Trial name
- NCT02732782
- Testing
- Isometric exercise, Eccentric exercise
- Where
- Germany
- Volunteers
- 45 people
- Sponsor
- Humboldt-Universität zu Berlin
Tendinopathy
Hyaluronan in the Treatment of Painful Achilles Tendinopathy.
The primary objective of this study is to compare OSTENIL® TENDON (2% hyaluronan) and Extracorporeal Shock Wave (ESWT) therapy in the treatment of painful Achilles tendinopathy.
- Trial name
- NCT01954108
- Testing
- hyaluronic acid sodium salt, ESWT
- Where
- 2 sites in Belgium, Germany
- Volunteers
- 62 people
- Sponsor
- TRB Chemedica AG
Plantaris Friction Syndrome, Non-Insertional Achilles Tendinopathy
Functional Improvement and UTC of the Achilles Tendon After Sodium Hyaluronate Injection for Plantaris Syndrome
This is a study to assess the benefit of sodium hyaluronate (Ostenil) injection for plantaris friction syndrome (PFS) associated with midportion Achilles tendinopathy.
- Trial name
- NCT03077009
- Testing
- Hyaluronic Acid
- Where
- 2 sites in United Kingdom
- Volunteers
- 33 people
- Sponsor
- Fortius Clinic
Tendinosis, Tendinopathy
Long-Term Follow-up of the Safety and Efficacy of RCT-01 in Men and Women With Unilateral, Chronic Achilles Tendinosis
The primary purpose of this study is to assess the long-term safety profile of RCT-01 injections as compared to placebo injections.
- Trial name
- ReaCT-X (NCT02655042)
- Where
- Canada
- Sponsor
- RepliCel Life Sciences, Inc.
Mid-Portion Achilles Tendinopathy
High Volume Injection in Mid Portion AChilles Tendinopathy
This prospective randomised clinical trial aims to evaluate the effectiveness of treatment for mid-portion Achilles tendinopathy in a real-world clinical setting, minimising the excessive control typically associated with…
- Trial name
- HighIMPACT (NCT06774066)
- Testing
- High volume image guided injection, Progressive rehabilitation exercise programme
- Where
- Malta
- Volunteers
- 20 people
- Sponsor
- University of Malta
Achilles Tendinopathy (AT)
Ozone Injection vs ESWT for Chronic Achilles Tendinopathy
This randomized controlled clinical trial compares ultrasound-guided local ozone injection, extracorporeal shock wave therapy, and conventional conservative treatment in patients with chronic Achilles tendinopathy.
- Trial name
- NCT07412652
- Testing
- Ultrasound-Guided Local Ozone Injection, Extracorporeal Shock Wave Therapy (ESWT), Conventional Conservative Treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 63 people
- Sponsor
- Ankara City Hospital Bilkent
Insertional Achilles Tendinopathy
Acupuncture for Insertional Achilles Tendinopathy Effectiveness
The purpose of this study is to compare acupuncture plus a prescribed home exercise program versus a prescribed home exercise program alone to determine which has better outcomes at improving pain relief and physical function in…
- Trial name
- NCT03747549
- Testing
- Acupuncture and Home Exercise, Home Exercise Alone
- Where
- 2 sites in United States
- Volunteers
- 38 people
- Sponsor
- Mike O'Callaghan Military Hospital
Plantar Fasciosis, Achilles Tendinosis
Clinical Evaluation of Placement of Radiofrequency-based Plasma Microdebridement in the Treatment Algorithm for Foot and Ankle Tendinosis and Plantar Fasciosis
To determine the magnitude of improvement for pain and function symptoms over a two year period after enrollment into the registry study in patients presenting with chronic heel pain and receiving standard of care treatment.
- Trial name
- TOPAZ Registry (NCT00420875)
- Testing
- TOPAZ MicroDebrider
- Where
- 3 sites in United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- ArthroCare Corporation
Achilles Tendon Injury, Achilles Tendon
CUHK Achilles Tendon Disorder Registry
This is a long-term research registry for patients with Achilles tendon disorders (like tears, chronic pain, or ruptures) as well as healthy adults without tendon problems.
- Conditions
- Achilles Tendon Injury, Achilles Tendon, Achilles Tendon Pain
- Trial name
- AT Registry (NCT07330414)
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Tendinopathy
Identification and Treatment of Early Tendinopathy in Elite Athletes
Tendon injuries represent a significant problem in elite athletes. The understanding of the pathophysiology of tendinopathy is very sparse, and especially the early events in tendinopathy are unknown.
- Trial name
- NCT03642392
- Testing
- Identification and treatment of early tendinopathy
- Where
- Denmark
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Bispebjerg Hospital
Achilles Tendinopathy (AT)
Effects of Tissue Flossing on Pain and Functional Performance in Patients With Achilles Tendinopathy
This study is a randomized controlled trial (RCT) investigating the effectiveness of tissue flossing as an adjunctive therapy for Achilles tendinopathy.
- Trial name
- NCT07519148
- Testing
- Tissue flossing, Eccentric exercises
- Where
- Pakistan
- Volunteers
- 30 people
- Sponsor
- Riphah International University
Achilles Tendinopathy (AT), Achilles Tendon Rupture
Immediate Effects of Neuromuscular Electrical Stimulation on Pain and Function in Achilles Tendon Disorders
The Achilles tendon exhibits high tensile strength and can withstand extremely high loads. However, it is susceptible to injuries such as tendinopathies and ruptures, which are associated with structural alterations and loss of…
- Trial name
- NCT07453485
- Testing
- Neuromuscular Electrical Stimulation (NMES)
- Where
- Brazil
- Volunteers
- 30 people
- Sponsor
- University of Brasilia
Achilles Tendinopathy, Patellar Tendinopathy
Early Implementation of Plyometric Exercises in the Rehabilitation of Individuals Suffering From Lower-Extremity Tendinopathies
This clinical trial aims to compare the effectiveness of an early plyometric exercise approach with traditional heavy, slow resistance training in treating tendinopathies of the Achilles tendon, patellar tendon, and plantar…
- Conditions
- Achilles Tendinopathy, Patellar Tendinopathy, Plantar Fasciopathy
- Trial name
- NCT06774547
- Testing
- Heavy-slow resistance training, Plyometric exercise
- Where
- Denmark
- Volunteers
- 120 people
- Sponsor
- Aalborg University
Achilles Tendinopathy
Backward Running on a Negative Slope as a Treatment for Achilles Tendinopathy in Runners
This study will look to evaluate the feasibility of a backwards downhill running program as an option for the treatment of Achilles tendinopathy in runners.
- Trial name
- NCT04632979
- Testing
- Backwards running on a Treadmil with a negative slope
- Where
- Israel
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Meuhedet. Healthcare Organization
Achilles Tendinitis, Right Leg, Achilles Tendinitis
Autologous Stem Cells in Achilles Tendinopathy
This study is looking at a new treatment, using the patient's own stem cells (the repair cells of the body), to see whether this can help reduce pain and promote healing of the Achilles tendon, without side effects.
- Conditions
- Achilles Tendinitis, Right Leg, Achilles Tendinitis, Achilles Degeneration, Achilles Tendon Thickening
- Trial name
- ASCAT (NCT02064062)
- Testing
- Autologous Mesenchymal Stem Cells
- Where
- United Kingdom
- Volunteers
- 10 people
- Sponsor
- University College, London
Achilles Tendon Pain
Achilles Pain Block
The purpose of this study is to better understand how the peripheral and central nervous system interact to produce the sensation of pain and motor patterns in patients with achilles tendinopathy (AT).
- Trial name
- APB (NCT03316378)
- Testing
- Ropivacaine injection
- Where
- United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Ruth Chimenti
Patellofemoral Pain Syndrome, Medial Tibial Stress Syndrome
Do Simple Running Technique Changes Reduce Pain and Change Injury Causing Mechanics
This project aims to investigate whether an increase in step rate can be used to reduce pain and injury causing movement patterns in runners who are currently experiencing achilles tendonopathy, iliotibial band syndrome…
- Conditions
- Patellofemoral Pain Syndrome, Medial Tibial Stress Syndrome, Iliotibial Band Syndrome, Achilles Tendinopathy
- Trial name
- NCT03067545
- Testing
- Step rate increase
- Where
- United Kingdom
- Volunteers
- 12 people
- Sponsor
- University of Salford