Clinical trials: Acne Rosacea
Rosacea
A Study to Evaluate the Safety and Efficacy of PAC-14028 Cream in Rosacea
This clinical study is to determine the optimum dose of PAC-14028 cream in a therapeutic confirmatory clinical study by evaluating the safety and therapeutic equivalence of PAC-14028 cream 0.1%, 0.3% and 1.0% in patients with…
- Trial name
- NCT02583009
- Testing
- PAC-14028 cream 0.1%, PAC-14028 cream 0.3%, PAC-14028 cream 1.0%
- Where
- South Korea
- Volunteers
- 216 people
- Sponsor
- Amorepacific Corporation
Papulopustular Rosacea
A Study to Evaluate the Long-Term Safety of Topical Administration of FMX103 in the Treatment of Moderate to Severe Papulopustular Rosacea
The primary objective is to show that open-label extended treatment with FMX103 1.5%, for up to an additional 40 weeks, is safe and well tolerated.
- Trial name
- NCT03276936
- Testing
- FMX103 1.5%
- Where
- 79 sites in United States
- Volunteers
- 504 people
- Sponsor
- Vyne Therapeutics Inc.
Papulopustular Rosacea
A Study of S5G4T-1 in the Treatment of Papularpustular Rosacea
To assess the efficacy and safety of S5G4T-1 compared to S5G4T-1 vehicle when applied once daily for 12 weeks in participants with papulopustular rosacea.
- Trial name
- NCT03564119
- Testing
- S5G4T-1, S5G4T-2
- Where
- United States
- Volunteers
- 372 people
- Sponsor
- Sol-Gel Technologies, Ltd.
Acne Rosacea
Determine the Effect of Administering Periostat(R) Twice Daily on Patients With Acne Rosacea
The purpose of this study is to determine whether Periostat(R), Doxycycline Hyclate 20 mg Tablets, taken twice daily is effective in reducing the red and white heads and overall redness associated with rosacea.
- Trial name
- NCT00041977
- Testing
- doxycycline hyclate 20 mg twice daily
- Where
- 7 sites in United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- CollaGenex Pharmaceuticals
Rosacea
An Evaluation of the Cosmetic Appearance of Metronidazole Gel (MetroGel®) 1%
The purpose of this study is to determine the cosmetic appearance of metronidazole gel (MetroGel®) 1% with commonly marketed facial foundations.
- Trial name
- NCT00668655
- Testing
- Metronidazole Gel
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Galderma R&D
Rosacea
The Suitability of Two Skin Care Regimens in Moderate to Severe Facial Rosacea
This study evaluates a nature-based sensitive skin regimen (NBSSR), as a suitable adjunct topical application to prescription medication when administered daily over the course of four weeks, in moderate to severe rosacea in…
- Trial name
- NCT03392558
- Testing
- Burt's Bees Skin Care Regimen, Control Regimen
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Burt's Bees Inc.
Papulopustular Rosacea
Safety and Efficacy of Azelaic Acid Foam, 15% in Papulopustular Rosacea
This study will investigate the safety and efficacy of a new formulation of an existing medication for the treatment of papulopustular rosacea. The study will test the active ingredient plus foam against foam alone.
- Trial name
- NCT01025635
- Testing
- Azelaic acid foam 15%, Vehicle foam
- Where
- 20 sites in United States
- Volunteers
- 401 people
- Sponsor
- LEO Pharma
Ocular Rosacea
Study of Lotilaner Ophthalmic Gel in Patients With Ocular Rosacea (KORE)
To evaluate lotilaner treatment in patients with ocular rosacea.
- Trial name
- NCT07443202
- Testing
- lotilaner, Vehicle
- Where
- 2 sites in United States
- Volunteers
- 155 people
- Sponsor
- Tarsus Pharmaceuticals, Inc.
Rosacea
A Study to Evaluate the Safety and Clinical Study of Azelaic Acid Gel 15% in Patients With Moderate Facial Rosacea
The purpose of the study is to compare the safety and efficacy profiles of a generic Azelaic Acid Gel, 15% to the reference listed Finacea® (azelaic acid) Gel, 15% in the treatment of moderate facial rosacea.
- Trial name
- NCT02120924
- Testing
- Azelaic acid, Vehicle, Finacea
- Where
- 30 sites in United States
- Volunteers
- 1,009 people
- Sponsor
- Actavis Inc.
Rosacea
Assessment of Rosacea Patients' Clinical Trial Experiences
Taking part in medical trials usually favors a particular demographic group. But there is limited research available to explain what trial attributes affect the completion of these specific demographic groups.
- Trial name
- NCT05747391
- Volunteers
- 500 people
- Sponsor
- Power Life Sciences Inc.
Rosacea
A Study Comparing Ivermectin Cream 1%, Soolantra™ Cream 1%, PrROSIVER® Cream1% to Placebo Control in the Treatment of Moderate to Severe Facial Rosacea.
The goal of this clinical trial is to evaluate and demonstrate the therapeutic equivalence and safety of Ivermectin Cream 1%, Soolantra™ Cream 1%, PrRosiver® Cream 1% \& to Placebo for the treatment of moderate to severe facial…
- Trial name
- NCT07795567
- Testing
- Ivermectin Cream 1%, Soolantra™ Cream 1%, PrRosiver® Cream 1%
- Where
- United States
- Volunteers
- 865 people
- Sponsor
- Sun Pharmaceutical Industries, Inc.
Bioequivalence
A Study Comparing Oxymetazoline 1% Cream to RHOFADE
randomized, double-blind, placebo controlled
- Trial name
- NCT05148689
- Testing
- Oxymetazoline hydrochloride Cream, 1%, Rhofade™ (oxymetazoline) cream, 1%
- Where
- United States
- Volunteers
- 82 people
- Sponsor
- Sun Pharmaceutical Industries, Inc.
Rosacea
Evaluation of Relapse, Efficacy and Safety of Long-term Treatment With Oracea® vs Placebo
The purpose of this study is to assess relapse, efficacy and safety in subjects with rosacea during long-term treatment with either Oracea® or placebo, after an initial 12-week regimen of Oracea® and MetroGel® 1%.
- Trial name
- NCT01426269
- Testing
- Doxycycline, Metronidazole
- Where
- 11 sites in United States
- Volunteers
- 235 people
- Sponsor
- Galderma R&D
Rosacea
A Therapeutic Equivalence Study of Two Metronidazole 1%Topical Gel Treatments for Patients With Rosacea
The objective of this study is to demonstrate that metronidazole 1% topical gel is effective for the treatment of patients with moderate to severe rosacea.
- Trial name
- MTZG (NCT01513863)
- Testing
- Metronidazole Topical Gel 1%, Metronidazole Topical Gel 1% (Metrogel)
- Where
- 22 sites in United States
- Volunteers
- 602 people
- Sponsor
- Sun Pharmaceutical Industries, Inc.
Rosacea
Safety and Tolerability of Oxymetazoline and Energy-Based Therapy in Participants With Rosacea
This study will evaluate the safety and tolerability of oxymetazoline HCl cream 1.0% when used as an adjunctive treatment to energy-based therapy for participants with moderate to severe persistent facial erythema associated with…
- Trial name
- NCT03380390
- Testing
- Oxymetazoline HCL 1.0% Cream, Energy-Based Therapy
- Where
- 4 sites in United States
- Volunteers
- 46 people
- Sponsor
- Aclaris Therapeutics, Inc.
Erythematotelangiectatic Rosacea
Feasibility Study: Ulthera System for the Treatment of Rosacea
Up to 12 subjects will be enrolled. Enrolled subjects will receive one or two Ultherapy treatments on the cheeks, depending on their assigned study group. Follow-up visits will occur 14, 30 and 90 days post-treatment.
- Trial name
- NCT01756027
- Testing
- Ulthera System providing one treatment per cheek, Ulthera System providing two treatments per cheek
- Where
- Canada
- Volunteers
- 12 people
- Sponsor
- Ulthera, Inc
Papulopustular Rosacea
Safety and Efficacy of Azelaic Acid Foam, 15 % in Papulopustular Rosacea
The purpose of this study is to assess the safety and efficacy of azelaic acid (AzA) foam, 15% topically applied twice daily for 12 weeks in subjects with papulopustular rosacea compared to its vehicle.
- Trial name
- NCT01555463
- Testing
- Azelaic acid foam, 15% (BAY39-6251), Vehicle foam
- Where
- 49 sites in United States
- Volunteers
- 961 people
- Sponsor
- LEO Pharma
Rosacea
4 Week In-Use Study Evaluating How Well-Tolerated a Skin Care Product Is on Adults With Facial Redness
The purpose of this study is to evaluate if the test sunscreen skin care product will be well-tolerated and help facial redness when applied to the face after 4 weeks.
- Trial name
- NCT03841032
- Testing
- Coppertone, BAY1183345
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- Bayer
Rosacea, Papulopustular
Rosacea Treatment Using Non-thermal (Cold) Atmospheric Plasma Device
10-13 patients will be enrolled to receive split face treatment: the control side will be treated with metronidazole cream, the intervention side will be treated with a cold atmospheric plasma device
- Trial name
- NCT05592548
- Testing
- cold atmospheric plasma
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- The Skin Center Dermatology Group
Rosacea
Assessment of the Rosacea Prevalence in the General Population
Multi-centre interventional cross-sectional prevalence study Assessment of the Rosacea Prevalence in the General Population.
- Trial name
- RISE (NCT02292797)
- Testing
- Prevalence assessment
- Volunteers
- 6,000 people
- Sponsor
- Galderma R&D