Clinical trials: Acne Rosacea
Rosacea
M89PF in Rosacea Associated With Erythema and Sensitive Skin
Rosacea is a common facial dermatosis, with flares induced by exposome factors. M89PF containing Vichy mineralizing water, probiotic fractions, hyaluronic acid, niacinamide and tocopherol repairs the skin barrier and reinforces…
- Trial name
- NCT05562661
- Where
- Italy
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cosmetique Active International
Acne, Atopic Dermatitis
Use of the SpiderMass for in Vivo Analysis of the Skin in Five Chronic Inflammatory Dermatosis
The physiological states of the skin are characterized by a certain homeostasis linked to the balance of the metabolic pathways. When these pathways are deregulated, the proteic, lipidic and metabolic is affected.
- Conditions
- Acne, Atopic Dermatitis, Psoriasis Vulgaris, Rosacea
- Trial name
- NCT04472546
- Testing
- in-vivo mesure, Scotch, Lipid index
- Where
- France
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Pierre Fabre Dermo Cosmetique
Rosacea
Efficacy of Oral Minocycline (Solodyn) and Oral Minocycline (Solodyn) Plus Azelaic Acid (Finacea) for Acne Rosacea
Rosacea is one of the most commonly occurring dermatoses treated by dermatologist today. Rosacea is an inflammatory condition of the skin presenting as flushing and or blushing along with redness, swelling, telangiectasia, and…
- Trial name
- NCT05014906
- Testing
- Minocycline 45 MG, Azelaic acid
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Dermatology Specialists Research
Rosacea
EVALUATION OF THE EFFECT OF THE PERFECTA V-BEAM LASER ON ROSACEA
The purpose of this study is to further quantify the safety and effectiveness of the Syneron-Candela long pulse-duration, extended sub-pulse, larger spot-size prototype Perfecta V-Beam, 595nm laser system for the treatment of…
- Trial name
- NCT03211585
- Testing
- Perfecta V-Beam laser
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Syneron Medical
Rosacea
Study to Evaluate the Long-term Safety of a Once-Daily Omiganan Topical Gel
This study evaluates the long-term safety of once-daily application of Omiganan topical gel in subjects with severe papulopustular rosacea.
- Trial name
- NCT02576847
- Testing
- Omiganan
- Where
- 28 sites in United States, Australia and 6 more
- Volunteers
- 307 people, healthy volunteers welcome
- Sponsor
- Maruho Co., Ltd.
Rosacea
A Clinical Endpoint Bioequivalence Study of "Oxymetazoline Hydrochloride Cream"
A Randomized, Double-blind, Parallel-group, Three-arm, Placebo-controlled, Multi-Site Therapeutic Equivalence Study with Clinical End-points Comparing Test Product "Oxymetazoline hydrochloride Cream, 1%" to Reference Product…
- Trial name
- NCT03954444
- Testing
- Oxymetazoline Hydrochloride, Rhofade Cream, 1%
- Where
- United States
- Volunteers
- 1,105 people, healthy volunteers welcome
- Sponsor
- Actavis Inc.
Papulopustular Rosacea
A Twelve Week Safety and Efficacy Study in Rosacea
The purpose of this study is to evaluate th safety and efficacy of one-daily topical application of CLS001 low, mid and high dose compared to vehicle gel in subjects with papulopustular rosacea.
- Trial name
- NCT01784133
- Testing
- omiganan
- Where
- 17 sites in United States
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Maruho Co., Ltd.
Acne, Actinic Keratosis
Potential Research Study Participant Registry
The purpose of the potential research study participant registry is to keep potential research subjects informed about any future research studies in which they may meet the criteria for enrollment.
- Conditions
- Acne, Actinic Keratosis, Dysplastic Nevi, Eczema
- Trial name
- NCT00710489
- Where
- United States
- Volunteers
- 265 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Rosacea
Effectivity and Safety of Metronidazole 1% Cream in Rosacea Therapy
Rosacea is a chronic inflammatory disease of the central facial region, which can also occur in the neck and chest regions. Microbes that play a role in rosacea are Demodex folliculorum and Helicobactor pylori.
- Trial name
- NCT05861310
- Testing
- Metronidazole 1% Cream,Top
- Where
- 2 sites in Indonesia
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Dr.dr.Irma Bernadette, SpKK (K)
Rosacea
Analysis of the Microbiome in Rosacea
The skin and gut microbiome of rosacea patients differs from individuals without rosacea and that the microbiome suffers from unique derangements in rosacea patients following antibiotic therapy.
- Trial name
- NCT04108897
- Testing
- Doxycycline, Ivermectin Topical
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Port-Wine Stain, Rosacea
Skin Imaging to Inform Laser Treatments
The purpose of this study is to obtain information (such as lesion depth, depth of the most superficial part of the lesion, and the size and density of blood vessels) with the assistance of an imaging device, and use this…
- Conditions
- Port-Wine Stain, Rosacea, Telangiectasia, Angioma
- Trial name
- NCT04336163
- Testing
- Optical Coherence Tomography
- Where
- United States
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- University of California, Irvine
Rosacea, Sensitive Skin
Clinical Benefit of M89PB in Subjects With Rosacea Associated With Erythema and Sensitive Skin
The aim of the study is to assess the efficacy of the product M89 probiotic fractions in improving the symptoms of rosacea patients with sensitive skin after 30 days of treatment, in comparison with an area treated with the…
- Trial name
- NCT04898582
- Testing
- Mineral 89 Probiotic Fractions
- Where
- Italy
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Institute of Skin and Product Evaluation, Italy
Rosacea
Pulsed Dye Laser (PDL) vs. Microsecond 1064-nm Nd:YAG Laser for Treatment of Diffuse Facial Redness
The primary objective of this study is to compare the efficacy of PDL and the 1064-nm Nd:YAG laser in the treatment of facial redness.
- Trial name
- NCT01529996
- Testing
- Pulse Dye Laser/YAG laser
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Rosacea
Study to Evaluate the Safety and Efficacy of a Once-Daily CLS001 Topical Gel Versus Vehicle
This study evaluates the safety and efficacy of once-daily application of CLS001 topical gel compared to vehicle gel in subjects with severe papulopustular rosacea.
- Trial name
- NCT02576860
- Testing
- CLS001 (Omiganan), Vehicle
- Where
- 47 sites in United States, Australia and 7 more
- Volunteers
- 263 people, healthy volunteers welcome
- Sponsor
- Maruho Co., Ltd.
Rosacea
To Evaluate the Therapeutic Equivalence and Safety in Treatment of Moderate Facial Rosacea
To demonstrate the superiority of the efficacy of the test and reference products over that of the placebo control in the treatment of moderate facial rosacea.
- Trial name
- NCT03689010
- Testing
- Azelaic acid foam 15%, Finacea® (Azelaic acid Foam) 15%, Vehicle of the test product
- Where
- United States
- Volunteers
- 1,116 people, healthy volunteers welcome
- Sponsor
- Sun Pharmaceutical Industries, Inc.
Rosacea, Papulopustular Rosacea
Photodynamic Therapy for Papulopustular Rosacea
Rosacea is a chronic inflammatory disorder that is characterized by severe flushing (transient erythema), non-transient erythema, papules, pustules, and telangiectasia.
- Trial name
- NCT02075671
- Testing
- Aminolevulinic acid topical solution 20%, Blu-U Light Therapy
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- George Washington University
Rosacea
Zinc Sulfate in the Treatment of Rosacea: A Randomized, Controlled Trial
Rosacea is a common chronic dermatological condition, characterized by recurrent or persistent redness, permanent dilation of small blood vessel causing small red lesions, and papules/pustules.
- Trial name
- NCT00395226
- Testing
- zinc sulfate
- Where
- United States
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Essentia Health
Papulopustular Rosacea
Study of TP-04 in Participants With Papulopustular Rosacea
This study is being done to evaluate the safety, tolerability, and efficacy of the study drug, TP-04, in participants with papulopustular rosacea (PPR).
- Trial name
- NCT05838170
- Testing
- Lotilaner Gel, 2.0%, Vehicle control gel
- Where
- 5 sites in Canada
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Tarsus Pharmaceuticals, Inc.
Rosacea
Demodex Density, Immune Response and Oxidative Stress in Rosacea Patients
Aim of study is to determine reactive oxygen products and antioxidant capacity with rosacea patients; to measure metalloproteinase level and inflammatory markers of immune response and investigate their corelation with demodex…
- Trial name
- NCT02556827
- Testing
- Obtaining a blood sample, Reflectance confocal microscopy, Sebumeter
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Istanbul Training and Research Hospital
Wrinkle, Rosacea
Evaluation of Cutera Excel V™ Laser With Green Genesis and Micro-Lens Array (MLA)Attachment
Evaluate the Cutera excel V™ Laser with Green Genesis and a Micro-Lens Array (MLA) Attachment
- Conditions
- Wrinkle, Rosacea, Scarring
- Trial name
- NCT03424304
- Testing
- Excel V™ Laser With Green Genesis
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cutera Inc.