Clinical trials: Acne Scarring
Atrophic Acne Scar
Combined Therapy for Acne Scars
Compare the effectiveness of nonablative fractional resurfacing to radiofrequency micrnoeedling for facial acne scars in all skin types
- Trial name
- NCT05105334
- Testing
- Nonablative fractional laser (Fraxel re:store, Solta Medical, Bothell, WA) alone, Nonablative fractional laser (Fraxel re:store, Solta Medical, Bothell, WA) alternating with microneedling with radiofrequency (Intracel, Perigee Medical, Redwood City, CA)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Goldman, Butterwick, Fitzpatrick and Groff
Acne Atrophica, PRP
Poly-L-Lactic Acid Threads Versus Platelet-Rich Plasma for Post-Traumatic Atrophic Scars
This study compares the efficacy and safety of poly-L-lactic acid (PLLA) threads versus platelet-rich plasma (PRP), both combined with subcision, in the treatment of post-traumatic atrophic scars.
- Trial name
- PLLA-PRP PTAS (NCT07775092)
- Testing
- subcision and PLLA threads' insertion, PRP and subcision (PRP-S)
- Where
- Egypt
- Volunteers
- 48 people
- Sponsor
- Tanta University
Acne Scar
Comparing the Efficacy of Topical Tazarotene Gel 0.1% v/s Microneedling in Atrophic Post Acne Scars
The purpose of this study was to compare the Efficacy of Topical Tazarotene gel 0.1% versus Microneedling in atrophic Post acne scars.
- Trial name
- NCT05573425
- Testing
- Tazarotene gel 0.1%, Microneedling
- Where
- Pakistan
- Volunteers
- 202 people, healthy volunteers welcome
- Sponsor
- Jinnah Postgraduate Medical Centre
Acne Scars - Mixed Atrophic and Hypertrophic
Treatment of Acne Scars With Fractional CO2 Laser Versus Radio-frequency Microneedling
The study is a prospective, randomized, controlled, intra-person split-face trial with blinded evaluations. The objective is to compare efficacy and adverse effects of ablative fractional CO2 laser resurfacing versus…
- Trial name
- NCT04252352
- Testing
- Ablative fractional CO2 laser resurfacing/Radio-frequency microneedling
- Where
- Denmark
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Aarhus University Hospital
Acne Scars - Atrophic
Efficacy and Safety of Combined Nanofat Injection With Either Platelet Rich Fibrin or Microneedling Versus Nanofat Injection Alone in the Treatment of Facial Atrophic Post Acne Scars
To compare the efficacy and safety of combined nanofat injection with either platelet rich fibrin or microneedling versus nanofat injection alone in the treatment of facial atrophic post acne scars.
- Trial name
- NCT07471854
- Testing
- nanofat injecion, Platelet rich fibrin, Microneedling
- Volunteers
- 42 people
- Sponsor
- Assiut University
Acne Scars - Mixed Atrophic and Hypertrophic, Acne
Pilot Study Investigating the Efficacy of Fat Grafting as a Treatment for Male and Female Facial Acne Scarring
This single-center, clinical trial consists of a one autologous fat grafting treatment followed by 3-month and 6-month post-treatment visits in order to assess the efficacy of fat grafting when used by men and women with facial…
- Trial name
- NCT04559022
- Testing
- Fat Grafting
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Hair Reduction, Tattoo Removal
Clinical Study to Evaluate the Safety and Efficacy of Candela Technology
This is a non-randomized, multi-center, open-label, prospective clinical study evaluating the clinical treatment with Candela Medical Technology.
- Conditions
- Hair Reduction, Tattoo Removal, Wrinkle, Acne
- Trial name
- NCT06202274
- Testing
- Nordlys, Gentle, Picoway, Vbeam, Profound, Profound Matrix, eTwo, Exceed, CO2RE
- Where
- 3 sites in United States, Israel
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Candela Corporation
Acne Scars
Clinical Study to Evaluate Alexandrite Laser for the Treatment of Acne Scars
The intended use of the Alexandrite laser device used in this study is to assess the efficacy and safety of the Alexandrite laser device for the treatment of acne scars on skin types V and VI.
- Trial name
- NCT04807179
- Testing
- Experimental: RF Device Arm
- Where
- 2 sites in United States
- Volunteers
- 39 people
- Sponsor
- Cynosure, Inc.
Acne Scars
The Efficacy and Safety of a Single 70% Glycolic Acid Peel With Vitamin C for the Treatment of Acne Scars
Our study involves the evaluation of a high potency chemical peel in its efficacy and safety profile for the treatment of acne scars.
- Trial name
- NCT02126657
- Testing
- 70% glycolic acid
- Where
- Singapore
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- National University Hospital, Singapore
Acne Vulgaris
Fractional CO2 Laser Delivery of Topical Insulin Versus Platelet Rich Plasma in Treatment of Atrophic Post Acne Scars
compare the efficacy and safety of treating atrophic post acne scars with topical insulin versus Platelet rich Plasma PRP combined with fractional ablative Co2 laser
- Trial name
- NCT06590909
- Testing
- Fractional CO2 laser assisted PDT
- Volunteers
- 22 people
- Sponsor
- Assiut University
Acne Scars - Mixed Atrophic and Hypertrophic
Comparison of 1,550 and 755 Laser in a Split-face Trial
Clinical Trial comparing the 1,550-nanometer fractionated photothermolysis system laser to the 755 nanometer picosecond laser using a split-face (Right-Left) comparison.
- Trial name
- NCT03988049
- Testing
- 1,550 fracionated photothermolysis laser, 755 picosecond laser
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- David Smart
Acne Vulgaris
Treatment of Acne Vulgaris Using NAFL in Combination With Isotretinoin and Pricking Blood Therapy
BACKGROUND Isotretinoin remains one of the first line medications for moderate-to-severe acne vulgaris (AV) but its side effect is a major concern for Asian patients.
- Trial name
- NCT04156815
- Testing
- 1,565nm NAFL, Oral isotretinoin, Pricking blood therapy
- Where
- China
- Volunteers
- 60 people
- Sponsor
- xjpfW
Dermatitis, Acne
PMCF Investigation of Medical Device ChitoCare® Medical
This is a post-marketing observational clinical investigation conducted as part of the post-market clinical follow-up of ChitoCare® Medical, aimed to confirm safety and efficacy according to the requirements of Regulation (EU)…
- Conditions
- Dermatitis, Acne, Conditions After Dematosurgical Procedures, Scars
- Trial name
- NCT06850389
- Testing
- ChitoCare® medical Wound Healing Gel, ChitoCare® medical Healing Spray
- Where
- 2 sites in Czechia
- Volunteers
- 214 people
- Sponsor
- Primex ehf
ATROPHIC ACNE SCARS
Comparison Of Outcome Of Microneedling With Autologous PRP Vs Microneedling With Topical Insulin In Treatment Of Post Acne Atrophic Scars.
Microneedling with topical INSULIN is a simple, effective tool for building body's new collagen layers and thus an alternative to all erosive techniques such as lasers, peels.
- Trial name
- NCT06002854
- Testing
- PRP( platelet rich plasma) and Insulin human
- Where
- Pakistan
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Jinnah Postgraduate Medical Centre
Cicatrix
A Pilot Study Testing Fractional Radiofrequency Versus Fractional Photothermolysis for the Treatment of Acne Scars
The purpose of this study is to compare the effectiveness of the ePrime fractional radiofrequency system to the 1550-nm fractional photothermolysis system (Fraxel) in the ability to improve acne scar appearance.
- Trial name
- NCT01976260
- Testing
- Fractional Radiofrequency, 1550-nm Fractional Photothermolysis
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Wrinkles, Fine Lines
Feasibility Study To Collect Safety And Preliminary Efficacy Data For A Radiofrequency Microneedling Device
The intended use of the Potenza™ device is to collect clinical data for brow lifting and/or treatment of dermatologic conditions in which electrocoagulation and hemostasis is a viable mechanism for means of improvement.
- Conditions
- Wrinkles, Fine Lines, Crepey Skin, Acne Scars
- Trial name
- NCT05254210
- Testing
- RF Device (Potenza™)
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Cynosure, Inc.
Acne Vulgaris, Post Inflammatory Hyperpigmentation
Tazarotene 0.045% Lotion for Treating PIE and PIH in Subjects With Acne
The purpose of the study is to assess the safety and efficacy of Arazlo Lotion (Tazarotene 0.045% Lotion) for treatment of postinflammatory erythema and postinflammatory hyperpigmentation in subjects with acne.
- Conditions
- Acne Vulgaris, Post Inflammatory Hyperpigmentation, Post Inflammatory Pigmentation Change, Erythema
- Trial name
- NCT05704114
- Testing
- Tazarotene 0.045% Lotion
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Dr. Emmy Graber
Acne Vulgaris, Atrophic Acne Scars
Adapalene 0.3% - Benzoyl Peroxide 2.5% Gel and Risk of Formation of Atrophic Acne Scars
This was a multi-centre, randomized, investigator blinded, vehicle controlled trial using intra-individual comparison (right half-face versus left half-face).
- Trial name
- OSCAR (NCT02735421)
- Testing
- ABPO Forte Gel, Vehicle gel
- Where
- 7 sites in Canada, France
- Volunteers
- 67 people
- Sponsor
- Galderma R&D
Atrophic Acne Scar
2940nm Er:YAG Laser and 1927nm Thulium Laser in Improving Atrophic Acne Scars
Fractional non-ablative laser (FNAL) has been widely used in improving acne scarring. However, there was only one study reported efficacy and safety of the fractional non-ablative 1927nm thulium laser (FTL) and no studies have…
- Trial name
- NCT04813419
- Testing
- 1927nm thulium laser, 2940nm Er:YAG laser
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Acne Vulgaris, Scar
Acne Scarring in Skin of Color: Laser vs Microneedling
Atrophic acne scars are a common and important sequelae of acne that affect up to 43-55% of patients with acne. Scarring impacts quality of life with reports of diminished self-esteem and frustration/sadness; additionally, some…
- Trial name
- NCT03395678
- Testing
- Microneedling, Fractional non-ablative 1,540nm laser
- Where
- United States
- Sponsor
- Boston University