Clinical trials: Acne Vulgaris, injection or injectable or infusion or IV or syringe or subcutaneous, open to volunteers
- Condition Acne Vulgaris
- Drug or intervention injection OR injectable OR infusion OR IV OR syringe OR subcutaneous
- Status Open to volunteers
Acne Scars - Atrophic
Efficacy and Safety of Combined Nanofat Injection With Either Platelet Rich Fibrin or Microneedling Versus Nanofat Injection Alone in the Treatment of Facial Atrophic Post Acne Scars
To compare the efficacy and safety of combined nanofat injection with either platelet rich fibrin or microneedling versus nanofat injection alone in the treatment of facial atrophic post acne scars.
- Trial name
- NCT07471854
- Testing
- nanofat injecion, Platelet rich fibrin, Microneedling
- Volunteers
- 42 people
- Sponsor
- Assiut University
Acne Scars - Mixed Atrophic and Hypertrophic, Hyperpigmentation
Efficacy and Tolerability of a Hybrid Fractional Laser for the Treatment of Acne Scars in Patients With Skin of Color
The investigators aim to investigate the efficacy and tolerability of a hybrid non-ablative/ablative laser for acne scarring in skin of color.
- Conditions
- Acne Scars - Mixed Atrophic and Hypertrophic, Hyperpigmentation, Laser-Induced Hyperpigmentation
- Trial name
- NCT05362929
- Testing
- Sciton Halo
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Montefiore Medical Center
Atrophic Acne Scarring
Poly-L-Lactic Acid in Atrophic Acne Scars
Background: Management of atrophic acne scars remains challenging due to their heterogeneous morphology and suboptimal response to conventional therapies.
- Trial name
- NCT07523217
- Testing
- injectable PLLA, PLLA threads
- Where
- Egypt
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Acne, Acne Papulopustulosa
Evaluation of the Efficacy and Safety of Fractional CO₂ Laser With and Without Intradermal Botulinum Toxin A in the Treatment of Inflammatory Facial Acne Vulgaris.
The goal of this clinical trial is to learn if fractional CO₂ laser (FCO₂) with and without intradermal Botulinum Toxin A can treat inflammatory facial acne vulgaris in adult patients of both genders.
- Trial name
- NCT07919886
- Testing
- Fractional co2 laser, Botulinium Toxin-A
- Where
- Egypt
- Volunteers
- 24 people
- Sponsor
- Cairo University
Acne
Study to Evaluate Safety, Efficacy and Immunogenicity of Acne mRNA Vaccine in Adults With Moderate to Severe Acne
The purpose of the trial is to evaluate the safety, efficacy and immunogenicity of up to 3 intramuscular injections of the Acne mRNA vaccine candidate at up to four dose levels in adult participants aged 18 to 45 years with…
- Trial name
- NCT06316297
- Testing
- Acne mRNA vaccine
- Where
- 94 sites in United States, Australia and 2 more
- Volunteers
- 800 people
- Sponsor
- Sanofi Pasteur, a Sanofi Company
Acne Scars, Ablative Fractional CO₂ Laser Therapy
Comparative Real-world Study on Ablative Fractional CO₂ Laser vs PRP With Microneedling for Acne Scar Treatment.
Road traffic accidents (RTAs) remain a major public health concern worldwide and in Bangladesh, contributing significantly to injury, disability, and premature death.
- Conditions
- Acne Scars, Ablative Fractional CO₂ Laser Therapy, Platelet-rich Plasma (PRP)
- Trial name
- NCT07189923
- Testing
- Ablative Fractional CO₂ Laser, Platelet-Rich Plasma (PRP) With Microneedling
- Where
- Bangladesh
- Volunteers
- 116 people
- Sponsor
- Dr. Sirajul Islam Medical College
Hidradenitis Suppurativa (HS), Hidradenitis Suppurativa (Acne Inversa)
Comparison of the Clinical Efficacy and Safety of Topical and Subcutaneous Injection of Secukinumab in HS
Secukinumab is currently approved in Europe, US and China for the treatment of moderate to severe HS as a biologic agent targeting IL-17A.Two phase III clinical trials (SUNSHINE and SUNRISE) showed that 300 mg s.c.
- Conditions
- Hidradenitis Suppurativa (HS), Hidradenitis Suppurativa (Acne Inversa), Secukinumab
- Trial name
- NCT07261072
- Testing
- Topical injection of Secukinmab, Subcutaneous injection of Secukinumab
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Peking Union Medical College
Acne
Study to Evaluate Safety, Efficacy and Immunogenicity of Acne mRNA Vaccine in Participants With Mild Acne
The purpose of the VBE00009 study is to evaluate the safety, efficacy and immunogenicity of 2 administrations of the Acne mRNA vaccine candidate at single dose level in participants aged 18 to 45 years with mild acne.
- Trial name
- NCT07013747
- Testing
- Acne mRNA vaccine
- Where
- 4 sites in United States
- Volunteers
- 228 people
- Sponsor
- Sanofi Pasteur, a Sanofi Company
Acne Scars, Acne Scars - Atrophic
Efficacy of Stromal Vascular Fraction on Acne Scar Correction
This study aims to evaluate the efficacy and safety of intradermal injection of autologous stromal vascular fraction (SVF) in the treatment of atrophic acne scars.
- Trial name
- NCT07094958
- Testing
- stromal vascular fraction (SVF), Normal Saline (NS)
- Volunteers
- 16 people
- Sponsor
- Seoul National University Hospital
Post-Acne Atrophic Scars, Carbon Dioxide Lasers
PRP Plus Fractional CO₂ Laser for Acne Scars
This randomized controlled trial aims to evaluate whether adding platelet-rich plasma (PRP) to fractional CO₂ laser resurfacing improves the treatment of moderate-to-severe acne scars compared with laser alone.
- Conditions
- Post-Acne Atrophic Scars, Carbon Dioxide Lasers, Platelet-Rich Plasma
- Trial name
- PRPLT (NCT07352215)
- Testing
- Fractional CO₂ Laser + Platelet-Rich Plasma (PRP), Fractional CO₂ Laser Only
- Where
- Pakistan
- Volunteers
- 70 people
- Sponsor
- Gujranwala medical college District Headquarters Hospital, Gujranwala
Acne
Safety, Tolerability, and Clinical Effectiveness of Adapalene/Clindamycin Phosphate Gel (Klenzit®-C) in Vietnamese Patients With Mild to Moderate Acne Vulgaris
The CLEAN ACNE Study is a prospective, observational, Phase IV, open-label, multicenter, single-arm study at 3-5 sites in Vietnam.
- Trial name
- Clean Acne (NCT07918001)
- Testing
- Klenzit®-C (Adapalene/Clindamycin Phosphate Gel)
- Where
- 3 sites in Vietnam
- Volunteers
- 225 people
- Sponsor
- IR INNOVATE RESEARCH PRIVATE LIMITED
Acne Vulgaris
A Study to Evaluate Efficacy and Safety of HB0043 in Aadult Patients With Moderate to Severe Acne Vulgaris.
The purpose of this study is to assess efficacy safety and tolerability of HB0043 in adult patients with moderate to severe AV.
- Trial name
- NCT07449156
- Testing
- HB0043
- Where
- China
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Shanghai Huaota Biopharmaceutical Co., Ltd.
Atrophic Acne Scar
Subcision With CO₂ Laser or PRP vs Subcision Alone in Atrophic Acne Scars
Acne vulgaris is an inflammatory disease of pilosebaceous unit ,leading to different types of scars including atrophic, hypertrophic and keloidal.
- Trial name
- NCT07199608
- Testing
- subcision, subcision+fractional co2 laser, subcision+PRP
- Where
- Egypt
- Volunteers
- 42 people
- Sponsor
- Assiut University
Atrophic Acne Scars
Subcision With Injection of Poly Deoxyribonucleotide Versus Subcision With Injection of Non-cross Linked Hyaluronic Acid in Rolling Acne Scars Treatment.
The aim of this study is to evaluate and compare the efficacy and safety of two different injectable agents combined with subcision for treating rolling acne scars.
- Trial name
- NCT07547956
- Testing
- subcision with PDRN vs HA injection
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Cairo University
Acne Scars
Evaluation of Juläine (TM) for the Treatment of Atrophic Facial Acne Scars
This study aims to evaluate the effectiveness and safety of Juläine, an injectable medical device made of polylactic acid, for treating facial acne scars.
- Trial name
- NCT07058883
- Testing
- Juläine
- Where
- 2 sites in Poland
- Volunteers
- 55 people
- Sponsor
- Nordberg Medical AB
Acne
Safety of the Acne mRNA Vaccine in Adolescents 12 to 17 Years of Age With Moderate to Severe Acne
The purpose of this study is to assess the safety profile of intramuscular injections of the Acne mRNA vaccine at 3 dose levels compared with placebo in 12 to 17 years old participants with moderate to severe acne.
- Trial name
- NCT07756957
- Testing
- Acne mRNA (messenger ribonucleic acid) vaccine
- Volunteers
- 410 people
- Sponsor
- Sanofi
Acne Scars
A Study to Assess the Safety and Effectiveness of ELAPR002f Injectable Gel in Adult Participants With Atrophic Acne Scars
Atrophic acne scars are flat, indented or with an inverted center scars that develop at the endpoint of the normal healing process for acne.
- Trial name
- NCT07207369
- Testing
- ELAPR002f Injectable Gel, Saline Control
- Where
- 10 sites in United States
- Volunteers
- 395 people
- Sponsor
- AbbVie
Acne Vulgaris
Topical 5% Spironolactone Gel Versus 0.1% Adapalene Gel for Acne Vulgaris: A Randomized Split-Face Study
Acne vulgaris is one of the most common dermatological conditions affecting adolescents and young adults. It results from multiple pathogenic factors, including increased sebum production, follicular hyperkeratinization…
- Trial name
- NCT07473895
- Testing
- Spironolactone 5% Topical Gel, Adapalene 0.1% Topical Gel
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Assiut University
Rosacea, Acne
Clinical Evaluation and Study of the Efficacy of a Centella Asiatica-Infused Facial Mask on Discosmetic Dermatosis
The purpose of this study was to investigate the efficacy and safety of repairing facial mask containing Asiaticum asiatica in treating disjunctive skin diseases.
- Conditions
- Rosacea, Acne, Centella, Melasma
- Trial name
- NCT06763367
- Testing
- Face mask containing Centella sinensis
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Nanjing First Hospital, Nanjing Medical University
Chronic Spontaneous Urticaria (CSU), Hidradenitis Suppurativa (HS)
SKIN Disease Profiling by an Exploratory, pRospective, Biomarker Study in dermatoloGY Practice (SKINERGY)
The goal of this observational study is to comprehensively profile six immune-mediated inflammatory diseases, including atopic dermatitis (AD), plaque psoriasis (PSO), hidradenitis suppurativa (HS), cutaneous T-cell lymphoma…
- Conditions
- Chronic Spontaneous Urticaria (CSU), Hidradenitis Suppurativa (HS), Psoriasis (PsO), Atopic Dermatitis (AD)
- Trial name
- SKINERGY (NCT07021495)
- Where
- 8 sites in Netherlands
- Volunteers
- 840 people, healthy volunteers welcome
- Sponsor
- Leiden University Medical Center