Clinical trials: Acoustic Stimulation
Chronic Stroke Patients
Multimodal Gait Training With and Without Rhythmic Auditory Stimulation in Chronic Stroke Patients
The primary goal of this randomized clinical trial is to investigate the efficacy of multimodal gait training, with and without rhythmic auditory stimulation, in improving gait, coordination and reducing fall risk in individuals…
- Trial name
- NCT06696950
- Testing
- Mutimodal gait training includes unilateral step training, inclined treadmill training, over ground training with rhythmic auditory stimulation, Multimodal gait training
- Where
- Pakistan
- Volunteers
- 42 people
- Sponsor
- Riphah International University
Schizophrenia and Schizoaffective Disorder
Effects of RAS in SZ
The two main groups of medicated patients with schizophrenia (SZ) are those receiving second-generation antipsychotics and those receiving first-generation antipsychotics.
- Trial name
- NCT07086040
- Testing
- RAS incorporated in upper-limb movement training, Upper-limb movement training
- Where
- Taiwan
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Shu-Mei Wang
Hemiplegia Due to Stroke, Parkinson Disease
Clinical Study of Rhythmic Auditory Stimulation for Gait Disorders
The aim of this clinical trial was to determine whether rhythmic auditory stimulation is effective in treating gait disorders in patients with post-stroke hemiplegia, primary Parkinson's disease, and various parkinsonism…
- Conditions
- Hemiplegia Due to Stroke, Parkinson Disease, Parkinsonian Syndrome
- Trial name
- NCT06837038
- Testing
- rhythmic auditory stimulation, No rhythm stimulation
- Where
- China
- Volunteers
- 60 people
- Sponsor
- YiCheng Zhu
Healthy Control
Auditory Stimulation Effect on Brain Oscillations and Sleep Dependent Learning
The investigators are testing the impact of quiet sounds played during sleep on brain oscillations and memory.
- Trial name
- NCT06688526
- Testing
- Quiet Sounds
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Auditory Processing Disorder
Hearing Aids for Veterans With Functional Hearing Difficulties
Every year, approximately 100,000 Veterans seek help at VA Audiology clinics for hearing and communication difficulties only to learn that they have normal hearing sensitivity.
- Trial name
- NCT06117254
- Testing
- Communication Counseling, Hearing Aids, Remote Microphones
- Where
- United States
- Volunteers
- 142 people
- Sponsor
- VA Office of Research and Development
Mild Cognitive Impairment (MCI), Amnestic Mild Cognitive Impairment - aMCI
Auditory Stimulation During Sleep to Enhance Long-Term Memory in Amnestic MCI
This study aims to evaluate the efficacy and safety of Elevvo AudiStim, a sleep auditory stimulation device, as a symptomatic treatment for patients with amnestic mild cognitive impairment (aMCI).
- Conditions
- Mild Cognitive Impairment (MCI), Amnestic Mild Cognitive Impairment - aMCI, Alzheimer or Mild Cognitive Impairment
- Trial name
- NCT07402590
- Testing
- Auditory Stimulation
- Where
- Spain
- Volunteers
- 37 people
- Sponsor
- Bitbrain
Schizophrenia
Restoring Spindle and Thalamocortical Efficiency in Early-Course Schizophrenia Patients Using Auditory Stimulation
The purpose of this research is to identify differences in brain activity during sleep between health individuals and individuals with schizophrenia, schizophreniform, or schizoaffective disorder.
- Trial name
- RESPITE (NCT05956951)
- Testing
- Closed-loop auditory stimulation
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Fabio Ferrarelli
Parkinson Disease
Amped-PD: Amplifying Physical Activity Through Music in Parkinson Disease
Regular, habitual exercise is a critical component of the long-term management of Parkinson disease (PD). However, PD-specific motor (e.g. slow and diminished movements, variable step timing) and non-motor (e.g.
- Trial name
- Amped-PD (NCT05421624)
- Testing
- Digital music therapeutic, Active-Control
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- Boston University Charles River Campus
Epilepsy, Sleep
Effect of Auditory Stimulation on Spike Waves in Sleep
Background: Close relationship exists between sleep slow wave (SSW) and the generation of spike wave in NREM-sleep. SSW are cortically generated oscillations alternating between excitatory depolarization ("Up-phase" of the SSW)…
- Trial name
- ECLASS (NCT02562885)
- Testing
- Acoustic pulses
- Where
- Switzerland
- Volunteers
- 6 people
- Sponsor
- University Children's Hospital, Zurich
Dementia, Acoustic Stimulation
Personalized Sensory Stimulation: Urban and Rural Dementia Care
As Taiwan transitions into a super-aged society, rising dementia rates have severely strained long-term care systems. Although current daycare centers provide multi-modal programs, they remain limited to behavioral training…
- Conditions
- Dementia, Acoustic Stimulation, Healthcare Disparities, Precision Medicine
- Trial name
- NCT07778277
- Testing
- Digital personalized intervention system (active setting), Gamma auditory stimulation device (active setting)
- Where
- Taiwan
- Volunteers
- 90 people
- Sponsor
- Chang Gung Memorial Hospital
Depression - Major Depressive Disorder, Insomnia
Auditory Stimulation for Insomnia and Depression
The goal of this clinical trial is to determine if alpha phase-locked auditory stimulation can improve sleep in people with insomnia and depression.
- Trial name
- NCT07553364
- Testing
- Alpha phase-locked auditory stimulation
- Where
- United States
- Sponsor
- Wake Forest University Health Sciences
Cochlear Implant, Hearing Loss
Combined Electric and Acoustic Hearing (EAS) in Children and Adults
Cochlear implants are surgically implanted devices which restore the ability to hear to the hearing impaired. Improvements in surgery and electrodes have results in an increased number of adults and children who have residual…
- Trial name
- NCT05923203
- Testing
- Electric and acoustic stimulation (EAS) technology in the implanted ear(s)-this is the combination of a cochlear implant (CI) and hearing aid (HA) in the implanted ear(s)
- Where
- 4 sites in United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Hearts for Hearing
Cochlear Implant
Place-based Mapping in EAS Listeners
Purpose: Investigate monaural and binaural hearing in electric-acoustic stimulation (EAS) users with place-based versus default maps.
- Trial name
- NCT04722042
- Testing
- place-based mapping, default mapping
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Hemiparesis
Combined Auditory and Functional Electrical Stimulation on Gait in Hemiparesis
Hemiparetic cerebral palsy has been characterized increased the asymmetry in the distribution of body weight between the affected and unaffected lower limbs and ineffective foot clearance during swing phase.
- Trial name
- NCT07331480
- Testing
- gait training, Exercise, control group gait training
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Insomnia, Sleep Initiation and Maintenance Disorders
Clinical Investigation to Observe the Long-term Safety and Efficacy of the Digital Medical Device 'BELL-001' in Patients Diagnosed With Insomnia
This study is a multicenter, single-arm, prospective clinical trial designed to observe the long-term safety and effectiveness of the digital medical device BELL-001 in patients diagnosed with insomnia.
- Trial name
- NCT07582809
- Testing
- BELL-001 Digital Therapeutic
- Where
- 3 sites in South Korea
- Volunteers
- 40 people
- Sponsor
- BELL Therapeutics Inc.
The Role of the LC-NA System in Sleep Regulation
The Role of the LC-NA System in Experimental Sleep Fragmentation
Sleep-wake regulation affects every person's life, yet the molecular mechanisms underlying these processes remain poorly understood.
- Trial name
- DMTN_FragSleep (NCT07167316)
- Testing
- DMTN, Auditory Stimulation, Placbo
- Where
- Switzerland
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Hans-Peter Landolt
Alzheimer's Disease (AD), Mild Cognitive Impairment (MCI) Amnestic
Acoustic Stimulation During Sleep: Effects on Memory and p-tau217 in MCI
The goal of this clinical trial is to determine whether acoustic stimulation during sleep can enhance slow-wave sleep (SWS), improve cognitive function, and reduce AD-related pathology in individuals with mild cognitive…
- Conditions
- Alzheimer's Disease (AD), Mild Cognitive Impairment (MCI) Amnestic, Cognitively Unimpaired
- Trial name
- PAS-MCI (NCT07529015)
- Testing
- Plase-Locked Acoustic Stimulation during slow-wave sleep
- Where
- Spain
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- Institut de Recerca Biomèdica de Lleida-Fundació Dr. Pifarré (IRBLleida)
Photoparoxysmal Abnormalities, Epilepsy
Prevention of Photoparoxysmal Abnormalities by Mozart K448
The purpose of this clinical trial is to examine the effect of non-invasive cortical activation by specific patterned auditory stimulation (Mozart K448- Piano Sonata for Two Hands in D Major), in altering or eliminating…
- Conditions
- Photoparoxysmal Abnormalities, Epilepsy, Seizures
- Trial name
- NCT01363154
- Testing
- Mozart K448, Beethoven's Für Elise, No music exposure
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Medical University of South Carolina
Hearing Loss, Sensorineural
Electric-Acoustic Stimulation Extended Follow-up Post Approval Study
The MED-EL EAS Extended Follow-up Study is an extended follow-up of the subjects who were enrolled in the pivotal study to assess long-term safety and device performance.
- Trial name
- NCT03031678
- Testing
- Electric-Acoustic Stimulation (EAS) Cochlear Implant System
- Where
- 7 sites in United States
- Volunteers
- 50 people
- Sponsor
- Med-El Corporation
Chronic Tinnitus
Interventional Treatment of Chronic Tinnitus With Acoustic Stimulation
The《Clinical practice guideline: tinnitus》defines tinnitus as the perception of sound without an external source, with patients lasting six months or longer classified as chronic tinnitus.
- Trial name
- NCT07185061
- Testing
- Acoustic Stimulation
- Where
- China
- Volunteers
- 200 people
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University