Clinical trials: Acquired Brain Injury
Acquired Brain Injury
Transition From Pediatric to Adult Care in Young Adults With Acquired Brain Injury
This retrospective, single-center observational study evaluates young adults with acquired brain injury who attended a joint pediatric-adult Physical and Rehabilitation Medicine transition consultation at Hôpitaux Paris Est…
- Trial name
- NEURO-TEA (NCT07881042)
- Where
- France
- Volunteers
- 72 people
- Sponsor
- Hopitaux de Saint-Maurice
Traumatic Brain Injury, Acquired Brain Injury
Feasibility and Outcomes of 3D-printed External Cranial Orthosis After Craniectomy
This study will compare the outcomes of a current clinical implementation of PEACO designed for one-handed donning and doffing with carer-monitoring with a previous prototype (HPPD) requiring carer-donning and doffing with…
- Conditions
- Traumatic Brain Injury, Acquired Brain Injury, Brain Tumor, Stroke
- Trial name
- NCT07122752
- Where
- Singapore
- Volunteers
- 32 people
- Sponsor
- Tan Tock Seng Hospital
Stroke, Acquired Brain Injury
Machine Learning to Predict Factors Affecting Rehabilitation Length of Stay and Healthcare Costs for Neurological Rehabilitation
The aim of this retrospective study is to ascertain total direct costs, rehabilitation length of stay (RLOS) and factors associated with RLOS for neurological inpatient rehabilitation at the tertiary care hospital.
- Conditions
- Stroke, Acquired Brain Injury, Traumatic Brain Injury, Brain Tumor
- Trial name
- NCT06704997
- Where
- Singapore
- Volunteers
- 10,000 people
- Sponsor
- Tan Tock Seng Hospital
Acquired Brain Injury, Mild Cognitive Impairment
Impact of Intensive Computerized Cognitive Training
To investigate factors that predict cognitive enhancement following engagement in an intensive Computerized Cognitive Training Protocol.
- Conditions
- Acquired Brain Injury, Mild Cognitive Impairment, Mild Neurocognitive Disorder
- Trial name
- CCT (NCT06130735)
- Testing
- Cognitive Computerized Training
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Brigham and Women's Hospital
Acquired Brain Injury Including Stroke, Epilepsy
Cognitive Rehabilitation Using Neurofeedback With Brain-computer Interface
The goal of this clinical trial is to determine whether a Brain-Computer Interface Neurofeedback Training (BCI-NFT) programme can improve cognitive outcomes, and whether electroencephalography (EEG)-based measures can serve as…
- Trial name
- NCT07828496
- Testing
- Brain-computer interface with neurofeedback with 3D game sessions
- Where
- Singapore
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- KK Women's and Children's Hospital
Acquired Brain Injury Including Stroke, TBI
Effects of Neurofeedback Training and tRNS on Attentional Deficits in Patients With Acquired Brain Injury
The goal of this study is to investigate new neuromodulation therapies for attention deficits following acquired brain injury. Brain damage can affect various domains, including motor and cognitive functions.
- Conditions
- Acquired Brain Injury Including Stroke, TBI, Stroke, Anoxia-Ischemia, Brain
- Trial name
- NeMoRe II (NCT07817316)
- Testing
- verum tRNS + Neurofeedback
- Where
- Spain
- Volunteers
- 30 people
- Sponsor
- Hospitales Nisa
Acquired Brain Injury, Disorder of Consciousness
Robotic vs. Traditional Verticalization in Patients With Severe Acquired Brain Injury: a Randomized Controlled Trial
In the rehabilitation project for patients with severe Acquired Brain Injury (sABI), it is essential to include exercises that facilitate the recovery of the upright position (or verticalization).
- Trial name
- VEM-sABI (NCT06469983)
- Testing
- ErigoBasic or ErigoPro®, Traditional Verticalization
- Where
- 6 sites in Italy
- Volunteers
- 118 people
- Sponsor
- Anna Estraneo
Acquired Brain Injury (Including Stroke), Spinal Cord Injury
Clinical Investigation to Validate the Safety and Performance of Integrating Functional Electrical Stimulation Into the ABLE Exoskeleton
The primary objective of this study is to validate the safety and clinical performance of the ABLE Exoskeleton with integrated Functional Electrical Stimulation (ABLE FES) in individuals with neurological conditions that impair…
- Conditions
- Acquired Brain Injury (Including Stroke), Spinal Cord Injury, Multiple Sclerosis
- Trial name
- NCT07550699
- Testing
- ABLE Exoskeleton with Functional Electrical Stimulation (ABLE FES)
- Where
- Austria
- Volunteers
- 14 people
- Sponsor
- ABLE Human Motion S.L.
Gait Impairment, Cerebral Palsy (CP)
Clinical Investigation to Validate the Safety and Performance of the ABLE Kids Device in Pediatric Patients With Neurological Gait Disorders in a Clinical Setting
The primary objective of the study is to validate the safety and clinical performance of the ABLE Kids device in pediatric patients with neurological gait disorders or muscular weakness during a 10-session gait training program…
- Conditions
- Gait Impairment, Cerebral Palsy (CP), Neuromuscular Diseases (NMD), Spinal Cord Injuries (SCI)
- Trial name
- NCT07745712
- Testing
- ABLE Kids
- Where
- Spain
- Volunteers
- 15 people
- Sponsor
- ABLE Human Motion S.L.
Disorder of Consciousness, Acquired Brain Injury
Describing the Effect of Familiar Song on Arousal and Awareness for Children With Disorders of Consciousness (DoC)
The goal of this clinical trial is to compare the effect of live music therapy and recorded music on recovery of consciousness in children aged 1 to 18 years who have a disorder of consciousness (DoC) after a severe brain injury.
- Trial name
- SongDoC (NCT07209657)
- Testing
- Live Music Therapy, Recorded Music
- Where
- Australia
- Volunteers
- 10 people
- Sponsor
- Murdoch Childrens Research Institute
Acquired Brain Injury Including Stroke
Effect of Functional Electrical Stimulation (FES) on Handwriting Rehabilitation After Acquired Brain Injury (ABI)
Study Purpose Functional Electrical Stimulation (FES) enhances motor recovery by increasing the functional range of motion to significantly improve muscle force deficits following an acquired brain injury.
- Trial name
- NCT07774715
- Testing
- Functional Electrical Stimulation (FES) on Handwriting Rehabilitation
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Texas Woman's University
Stroke, Subarachnoid Hemorrhage
MUSic Therapy In Complex Specialist Neurorehabilitation
Aim: Investigate whether patients undergoing specialist rehabilitation after complex neurological injury show different functional outcomes if music therapy is included in their rehabilitation program compared to usual care.
- Conditions
- Stroke, Subarachnoid Hemorrhage, Traumatic Brain Injury, Tumor, Brain
- Trial name
- MUSICS (NCT05777499)
- Testing
- Music Therapy, Control Therapy
- Where
- United Kingdom
- Volunteers
- 80 people
- Sponsor
- University College, London
Acquired Brain Injury
Development of a Soft Robotic Device for Rehabilitation and Assistance of the Upper Limb for People With Neurological Disorders
Development of a soft robotic device for rehabilitation and assistance of the upper limb for people with neurological disorders (FRONTIER)
- Trial name
- FRONTIER (NCT07750314)
- Testing
- FRONTIER Soft Exoskeleton
- Where
- Italy
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Università Vita-Salute San Raffaele
Acquired Brain Injury
Exercise and Physical Activity in Adults With Acquired Brain Injury
Exercise and physical activity in adults with acquired brain injury
- Trial name
- PA_ABI (NCT06895226)
- Testing
- Exercise, Usual Care
- Where
- Spain
- Volunteers
- 30 people
- Sponsor
- Universidade da Coruña
Acquired Brain Injury (Including Stroke)
Neuropsychiatric Outcomes and Disrupted Sleep Following Acquired Brain Injury
The two most common causes of brain injury are stroke and trauma. Both sleep and mental health problems are common after brain injury; we will investigate whether there is a relationship between poor sleep quality and worse…
- Trial name
- NODS (NCT07215195)
- Where
- United Kingdom
- Volunteers
- 150 people
- Sponsor
- University of Oxford
Acquired Brain Injury
Hospital and Home Rehabilitation Based on Social Care Robotics and Artificial Intelligence for Pediatric Patients
This study describes a prospective, longitudinal, randomized controlled trial evaluating Inrobics Rehab, a CE-marked Class I medical device (reg.
- Trial name
- INROBICS (NCT07448103)
- Testing
- Robot-assisted, gamified pediatric upper-limb rehabilitation (hybrid clinic + home program)
- Where
- Spain
- Volunteers
- 30 people
- Sponsor
- Inrobics Social Robotics, S.L.
Severe Acquired Brain Injury, Cognitive Impairment
Feasibility and Acceptability of StimolIrpinia for Cognitive Rehabilitation After Severe Acquired Brain Injury
This single-center pilot study evaluates the feasibility, acceptability, usability, and preliminary stimulus validation of StimolIrpinia, a multimedia repository of culturally and territorially relevant autobiographical stimuli…
- Conditions
- Severe Acquired Brain Injury, Cognitive Impairment, Cognitive Rehabilitation, Neurorehabilitation
- Trial name
- StimolIrpinia (NCT07718321)
- Testing
- StimolIrpinia-supported cognitive rehabilitation activities
- Where
- Italy
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Alfonso Magliacano
Consciousness Disorders, Severe Acquired Brain Injury
Cross-cultural Adaptation and Multicenter Validation of the Italian Versions of the Brief Evaluation of Receptive Aphasia (BERA) and SWallowing Assessment in Disorders of Consciousness (SWADOC)
Patients with severe acquired brain injury may evolve from coma into prolonged disorders of consciousness. In these patients, residual language comprehension and swallowing abilities are difficult to evaluate because standard…
- Trial name
- NCT07711119
- Testing
- Italian SWallowing Assessment in Disorders of Consciousness (SWADOC), Italian Brief Evaluation of Receptive Aphasia (BERA)
- Where
- 4 sites in Italy
- Volunteers
- 79 people
- Sponsor
- Alfonso Magliacano
Acquired Brain Injury
Virtual Reality vs Traditional Cognitive Training in Patients With Severe Acquired Brain Injury
Considerable evidence exists for using Virtual Reality (VR) for rehabilitation of acquired brain injury (ABI), with a particular focus on stroke.
- Trial name
- VR-sABI (NCT06474871)
- Testing
- Khymeia®-Virtual Reality rehabilitation System (VRRS EVO SYSTEM or COMPACT VRRS ENGINE), Traditional cognitive training (TCT)
- Where
- 5 sites in Italy
- Volunteers
- 28 people
- Sponsor
- Anna Estraneo
Disorders of Consciousness, Acquired Brain Injury
Spontaneous Eye Blinking Evaluation for Cognitive Assessment of Individuals With Severe Acquired Brain Injury
Assessment of consciousness and attention in individuals with severe Acquired Brain Injury (sABI) is crucial for planning rehabilitation, but it is often hindered by coexisting sensory-motor and/or cognitive-behavioural…
- Trial name
- SEE-ABI (NCT06464549)
- Testing
- EEG-EOG recording at rest and during an auditory oddball paradigm
- Where
- 2 sites in Italy
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Alfonso Magliacano