Clinical trials: Acquired Immune Deficiency Syndrome
Healthy Subjects, Infection, Human Immunodeficiency Virus
GSK1349572 Drug Interaction Study With Protease Inhibitors
A study in healthy volunteers to determine whether there is a drug interaction between GSK1349572 and the HIV protease inhibitors lopinavir/ritonavir and darunavir/ritonavir
- Trial name
- NCT00774735
- Testing
- GSK1349572
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
The Study Goal is to Assess the Introduction of Sustainable Family Planning/Reproductive Health Information and Services Through, Land O' Lakes-supported Dairy Cooperatives
Family Planning Through Dairy Cooperatives
This observational study will assess a model for providing family planning through quarterly events organized by dairy cooperatives supported by Land O'Lakes in Kenya.
- Trial name
- NCT01226433
- Where
- Kenya
- Volunteers
- 319 people, healthy volunteers welcome
- Sponsor
- FHI 360
HIV Infections, Salmonella Infections
Prospective Comparison of Ampicillin / Amoxicillin Versus Ceftriaxone for the Treatment of Salmonella Infections in AIDS Patients
To compare the effectiveness of standard treatment with parenteral ampicillin and oral amoxicillin compared to initial daily therapy with ceftriaxone followed by 3 times weekly suppressive treatment for salmonella infections in…
- Trial name
- NCT00002052
- Testing
- Ceftriaxone sodium, Ampicillin sodium, Amoxicillin trihydrate
- Where
- United States
- Sponsor
- University of Southern California
HIV/AIDS
HIV Oral Testing Infographic Experiment
Premised on the National AIDS Strategy's focus on identifying new HIV infections through increased HIV testing, the purpose of this formative pilot study is to develop and test an integrated HIV self-testing strategy that…
- Trial name
- HOTIE (NCT04061915)
- Testing
- Infographic Intervention, Paper-based HIV self-testing information
- Where
- United States
- Volunteers
- 322 people, healthy volunteers welcome
- Sponsor
- New York University
HIV/AIDS
Duo Partnership Adherence Commitment Therapy
This is a randomized controlled trial of a new behavioral intervention designed to improve engagement in HIV care for couples. Investigators will compare the HIV viral load outcomes of couples randomized to a couples-based…
- Trial name
- DuoPACT (NCT02925949)
- Testing
- DuoPACT, LifeSteps
- Where
- United States
- Volunteers
- 288 people
- Sponsor
- University of California, San Francisco
Hiv
An Observational Retrospective Database Analysis to Evaluate Raltegravir Based-regimens, Including NUC-sparing Regimens, in Aged HIV Patients.(RalAge)
This is an observational retrospective cohort in real world to describe RAL data, including NUC-sparing regimens, in aged HIV patients. It is a phase IV study.
- Trial name
- RalAge2 (NCT03579485)
- Where
- Italy
- Volunteers
- 90 people
- Sponsor
- Azienda Policlinico Umberto I
AIDS
Evaluation of the Immune Response of a HIV Candidate Vaccine After Administration of One Chloroquine Dose
The purpose of this study is to evaluate the safety and reactogenicity of one booster dose of a HIV candidate vaccine after administration of one oral dose of chloroquine.
- Trial name
- NCT00972725
- Testing
- GSK Biologicals' HIV vaccine (732461), Chloroquine
- Where
- Belgium
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
HIV/AIDS
Early Access to ART for All in Swaziland: Effects on Economic Outcomes
The purpose of this study is to evaluate the impact of offering early antiretroviral therapy to HIV-positive individuals in government-managed health facilities in Swaziland on a range of economic outcomes
- Trial name
- NCT03789448
- Testing
- Early Access to ART for All
- Volunteers
- 3,019 people
- Sponsor
- Till Bärnighausen
HIV Infections, Measles
A Phase II, Comparative Study of Seroconversion of Single-Dose and Two-Dose Measles Vaccination in HIV-Infected and HIV-Uninfected Children: A Multicenter Trial of the Pediatric AIDS Clinical Trials Group
To compare measles seroconversion rates (development of antibodies) at 13 months of age in HIV-infected and uninfected children on one of two immunization schedules: attenuated measles/mumps/rubella virus (M-M-R II) vaccine at 12…
- Trial name
- NCT00000815
- Testing
- Attenuvax, M-M-R-II
- Where
- 46 sites in United States, Puerto Rico
- Volunteers
- 270 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Human Immunodeficiency Virus
Quantitative HPV Genotyping in Screening of Anal Intraepithelial Neoplasia in HIV-positive Patients
The pathophysiology from anal HPV infection to Anal Intraepithelial Neoplasia is less well understood than cervical HPV infection.
- Trial name
- GAIN (NCT03742375)
- Testing
- HPV genotyping
- Where
- Belgium
- Volunteers
- 24 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Adult Women Living With HIV/AIDS, Intimate Partner Violence
Clinic-Community Bridge to Improve Health Outcomes for Abused Women Living With HIV/AIDS
Women living with HIV/AIDS (WLWHA) in Baltimore experience disproportionately high rates of intimate partner violence (IPV), housing instability, and food insecurity, which adversely affect health outcomes.
- Trial name
- Bridges (NCT07553312)
- Where
- United States
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
HIV/AIDS, Tuberculosis
Drinkers' Intervention to Prevent Tuberculosis (DIPT Study)
There is an urgent global need to decrease the high mortality of tuberculosis (TB) in persons with HIV as TB is the leading cause of death among persons with HIV worldwide.
- Trial name
- DIPT (NCT03492216)
- Testing
- Incentives for negative EtG test, Incentives for positive IsoScreen test
- Where
- 2 sites in Uganda
- Volunteers
- 680 people
- Sponsor
- University of California, San Francisco
Human Immunodeficiency Virus, Acquired Immune Deficiency Syndrome
Mentor Mothers: A Sustainable Family Intervention in South African Townships
The purpose of this study is to test a mother-to-mother intervention during pregnancy and after delivery with Mothers Living with HIV (MLH)in South Africa.
- Conditions
- Human Immunodeficiency Virus, Acquired Immune Deficiency Syndrome, Tuberculosis
- Trial name
- NCT00972699
- Testing
- Peer support and mentoring
- Where
- South Africa
- Volunteers
- 1,200 people
- Sponsor
- University of California, Los Angeles
Acquired Immunodeficiency Syndrome, Blood Transfusion
Viral Activation Transfusion Study (VATS)
The purpose of the trial was to determine if transfusion of allogeneic blood to HIV-1 infected persons led to immune activation and consequent induction of HIV-1 or /or Cytomegalovirus (CMV) replication, and whether this…
- Conditions
- Acquired Immunodeficiency Syndrome, Blood Transfusion, Cytomegalovirus Infections, HIV Infections
- Trial name
- NCT00000593
- Testing
- blood transfusion
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
HIV (Human Immunodeficiency Virus)
Exploration of the Variability of Exposure to Antiretroviral Treatment in Hair With a View to Validating Its Value as a Diagnostic Tool for Partial and/or Total Non-compliance With Treatment
Treatment adherence is defined by compliance with the dosage schedule (i.e., dose per dose and number of doses per day), as well as the duration of administration (i.e., number of days during which the dosage schedule must be…
- Trial name
- HAIROBS (NCT07062614)
- Testing
- Hair sampling and questionnaires answers for Patients with Lamivudine or Emtricitabine treatment
- Where
- France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Toulouse
Hiv, Serious Mental Illness
RCT of an Intersectional Stigma Intervention to Sustain Viral Suppression Among Women Living With Serious Mental Illness and HIV in Botswana
The study goal is to promote viral load suppression among women with serious mental illness (SMI) and HIV in Botswana, given that these women are especially vulnerable to psychiatric medication nonadherence and symptom…
- Trial name
- NCT05807867
- Testing
- WMM-based intersectional stigma intervention
- Where
- Botswana
- Volunteers
- 360 people
- Sponsor
- New York University
HIV Infections
Specialized Cognitive-Behavioral Counseling Intervention to Reduce HIV Transmission Risk Behavior in HIV-Infected Men
This study will evaluate the effectiveness of a specialized cognitive-behavioral counseling intervention in reducing sexual risk behaviors in men who are HIV-infected and report having unprotected sex with male partners who are…
- Trial name
- NCT00218712
- Testing
- Cognitive behavioral intervention, Standard counseling
- Where
- 2 sites in United States
- Volunteers
- 488 people
- Sponsor
- University of California, San Francisco
Human Immunodeficiency Virus, Metabolic Syndrome
2-5 Intermittent Caloric Restriction in HIV
Background: Weight gain can lead to obesity and diabetes even in people living with human immunodeficiency virus (HIV). Researchers want to see if the technique intermittent calorie restriction can help overweight people with HIV…
- Trial name
- 2-5toWIN (NCT03489109)
- Testing
- Intermittent fasting, Standard of Care
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
HIV/AIDS
Project RAP: Family-based HIV Prevention in the Juvenile Drug Court
The purpose of this project is to compare the effect of a family-based HIV prevention program to the effect of an adolescent-only health promotion program on adolescent HIV risk and marijuana use among adolescents enrolled in the…
- Trial name
- Project RAP (NCT01403298)
- Testing
- Family-Based HIV prevention, Adolescent Only Health Promotion
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Sarcoma, Kaposi, HIV Infections
Use of Stealth Liposomal Doxorubicin HCl ( DOX-SL ) in the Treatment of Moderate to Severe AIDS-Related Kaposi's Sarcoma.
To provide Stealth liposomal doxorubicin hydrochloride ( DOX-SL ) as a therapy for Kaposi's sarcoma patients who have no remaining treatment options other than DOX-SL or patients who have been participating in another DOX-SL…
- Trial name
- NCT00002147
- Testing
- Doxorubicin hydrochloride (liposomal)
- Where
- United States
- Sponsor
- Sequus Pharmaceuticals
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