Clinical trials: Acquired Immune Deficiency Syndrome (AIDS)
HIV Disease
Autonomic Neuropathy, GI Motility, and Inflammation in HIV
The purpose of this study is to explore a possible link between the autonomic nervous system and immune function in patients with HIV.
- Trial name
- ANGI (NCT02850276)
- Testing
- Pyridostigmine
- Where
- United States
- Volunteers
- 76 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Candidiasis, Oral, HIV Infections
The Safety and Effectiveness of Peridex in Preventing or Delaying Fungal Infections of the Mouth in HIV-Infected Patients
To evaluate the safety and effectiveness of Peridex (an oral rinse containing chlorhexidine gluconate) for preventing the occurrence of clinically-evident microbiologically-documented oral candidiasis in HIV-positive patients…
- Trial name
- NCT00002431
- Testing
- Chlorhexidine gluconate
- Where
- 5 sites in United States
- Sponsor
- Procter and Gamble
Hepatitis C, Hepatitis C, Chronic
Impact of DAA Uptake in Controlling HCV Epidemic and Modeling Interventions for HCV Elimination Among HIV-infected Persons in San Diego
A retrospective and prospective study among people living with HIV (PLWH) that assesses hepatitis C (HCV) treatment uptake during periods before and after direct acting antivirals (DAA) introduction, and its impact on the HCV…
- Conditions
- Hepatitis C, Hepatitis C, Chronic, HIV/AIDS
- Trial name
- NCT03551002
- Where
- United States
- Volunteers
- 450 people
- Sponsor
- University of California, San Diego
HIV Infections, HIV Wasting Syndrome
Growth Hormone in the Treatment of HIV-Associated Wasting
The purpose of this study is to compare physical function and lean body mass in patients getting different doses of somatropin compared to patients not getting the drug.
- Trial name
- NCT00489528
- Testing
- Somatropin; Recombinant human growth hormone (r hGH)
- Sponsor
- EMD Serono
HIV, HIV Infections
Mobile Phone Technology for Prevention of Mother-to-Child Transmission of HIV: Acceptability, Effectiveness, and Cost (Kenya)
Although gains have been made in achieving the health-related Millennium Development Goals (MDG), much is still needed in countries affected by high levels of HIV/AIDS.
- Conditions
- HIV, HIV Infections, AIDS, Antiretroviral Therapy
- Trial name
- NCT01645865
- Testing
- Control, Intervention
- Where
- Kenya
- Volunteers
- 600 people
- Sponsor
- Elizabeth Glaser Pediatric AIDS Foundation
Primary Care Appointment Keeping
Intervention to Retain HIV-positive Patients in Medical Care
PROJECT OVERVIEW This research is a collaboration between the Centers for Disease Control and Prevention (CDC), the Health Resources and Services Administration (HRSA), and six university-affiliated HIV clinics in the United…
- Trial name
- Phase II (NCT01537367)
- Testing
- Enhanced contact plus behavioral skills, Enhanced contact only, Standard of Care
- Where
- 6 sites in United States
- Volunteers
- 1,838 people
- Sponsor
- Centers for Disease Control and Prevention
Sexually Transmitted Infections, HIV Infections
Sexually Transmitted Infections Among African American Women Who Have Sex With Women
The purpose of this study is to determine the rates of sexually transmitted infections (STI) among a group of African American women who have sex with women (AA WSW).
- Trial name
- WSW (NCT01043081)
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- University of Mississippi Medical Center
Human Immunodeficiency Virus, Hepatitis B
Notification of Donors With Positive Microbiology Markers
Each year around 200 blood donors in the UK are found to be infected with blood-borne diseases (HIV, hepatitis B, hepatitis C, and HTLV), while several others have been identified as having an increased risk of variant…
- Conditions
- Human Immunodeficiency Virus, Hepatitis B, Hepatitis C, Human T-lymphotropic Virus I & II
- Trial name
- NCT01050881
- Where
- United Kingdom
- Volunteers
- 217 people
- Sponsor
- NHS Blood and Transplant
HIV Infections
A Double-Blind Study to Evaluate the Safety and Pharmacokinetics of L-Ofloxacin (RWJ 25213) in Subjects With HIV Infection
To determine the safety and pharmacokinetics of L-ofloxacin (RWJ 25213) in patients with HIV infection.
- Trial name
- NCT00002249
- Testing
- Levofloxacin
- Where
- United States
- Sponsor
- R W Johnson Pharmaceutical Research Institute
HIV Infection, Cardiovascular Disease
HIV Treatment and CVD Events
Cardiovascular disease (CVD) has been associated with HIV infection. However, it is uncertain whether increased CVD rates are associated with HIV-related factors (e.g., HIV-infection or highly active antiretroviral therapy…
- Conditions
- HIV Infection, Cardiovascular Disease, Infection, Human Immunodeficiency Virus, Acute Myocardial Infarction
- Trial name
- NCT01054638
- Testing
- HAART Treatment
- Sponsor
- ViiV Healthcare
Hiv
Assisted Partner Services and HIVST in Western Kenya
This study includes different designs with Aim 1 being a cluster randomized controlled trial to investigate the use of HIV self-testing (HIVST) as a mode of HIV testing in Western Kenya in addition to the standard of care…
- Trial name
- NCT04774835
- Testing
- HIVST, Standard aPS
- Where
- United States
- Volunteers
- 4,941 people
- Sponsor
- University of Washington
HEPATITIS C, Virus, Human Immunodeficiency
Antiviral Pharmacology and Adherence in Drug Users
Approximately one half of all Americans living with Hepatitis C virus (HCV) are drug users, yet they are the least likely to receive HCV treatment.
- Trial name
- NCT02573376
- Testing
- Directly Observed Therapy, Wirelessly Observed Therapy
- Where
- United States
- Volunteers
- 73 people
- Sponsor
- University of Colorado, Denver
HIV/AIDS
Contribution of "Praise Messages" to HIV Treatment Retention and Adherence Among Female Sex Workers in Ethiopia
This study evaluates the effects of praise message phone calls on antiretroviral therapy (ART) initiation, adherence, and prescription refills.
- Trial name
- NCT03127397
- Testing
- Praise message phone call
- Where
- Ethiopia
- Volunteers
- 810 people
- Sponsor
- Reed College
HIV, AIDS
The DC Cohort Longitudinal HIV Status Neutral Study
The goal of the DC Cohort is to establish a clinic-based city-wide longitudinal cohort that will describe clinical outcomes, and improve the quality of care for patients diagnosed with Human Immunodeficiency Virus/Acquired Immune…
- Trial name
- DC Cohort (NCT01206920)
- Where
- 14 sites in United States
- Volunteers
- 19,000 people, healthy volunteers welcome
- Sponsor
- George Washington University
HIV Infection
Demonstrating Safety and Effective Delivery of Daily Oral Pre-exposure Prophylaxis (PrEP) for Sex Workers in India
Female sex workers (FSWs) in India are at high risk of HIV infection, and while correct and consistent condom use is an effective means of preventing HIV transmission, many FSWs have difficulty insisting on their use.
- Trial name
- PrEP-India (NCT02148094)
- Testing
- Truvada
- Where
- 2 sites in India
- Volunteers
- 1,325 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
HIV, AIDS
Atripla to Stribild Switch Study to Evaluate Sleep Disturbances
Switch patients from Atripla to Stribild will be evaluated to see if patients have less sleep disturbances.
- Conditions
- HIV, AIDS, Sleep Disorders
- Trial name
- NCT02477527
- Testing
- Stribild
- Volunteers
- 21 people
- Sponsor
- Midtown Medical Center, Tampa, FL
HIV/AIDS
Operations Research of the 'Real World' Effectiveness of Multi-Month Dispensing of ART for Stable Patients in CARGs in Zimbabwe
This study aims to evaluate the effectiveness of two strategies for multi-month dispensing (MMD) of ART in Community ART Refill Groups (CARGs) on retention, virologic suppression, and cost compared to standard of care.
- Trial name
- NCT03238846
- Testing
- Three month dispensing of ART in CARGs, Six month dispensing of ART in CARGs
- Where
- 30 sites in Zimbabwe
- Volunteers
- 4,676 people
- Sponsor
- Kheth'Impilo
Atherosclerosis
Inflammation, Viral Replication, and Atherosclerosis in Treated HIV Infection
This is a longitudinal observational study of HIV-infected patients and HIV-negative control patients that is being conducted to learn more about immunologic factors, inflammation, and cardiovascular risk in patients with HIV…
- Trial name
- NCT01519141
- Where
- United States
- Volunteers
- 579 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Acquired Immunodeficiency Syndrome, HIV Infections
Computer-Assisted Adherence Program for Patients Taking Anti-HIV Drugs
The purpose of this study is to evaluate the effectiveness of a computer-assisted, self-administered adherence program for patients on complicated anti-HIV drug regimens.
- Trial name
- NCT00051766
- Testing
- Computer-based Intervention
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
HIV Infections
Cerebrospinal Fluid (CSF) Raltegravir Substudy
The purpose of this study is to measure concentrations of Raltegravir in cerebrospinal fluid. The hypotheses are: Raltegravir concentrations in CSF will be measurable Raltegravir concentrations in CSF will remain constant, while…
- Trial name
- NCT00718029
- Volunteers
- 4 people
- Sponsor
- University of California, San Diego
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