Clinical trials: Active Ageing
Physical Activity, Biological Aging
Exercise Referral Schemes Enhanced by Self-Management Strategies to Battle Sedentary Behaviour
The increase of the elderly population leads to increased prevalence of frailty, risk for poor health outcomes, and related health and social care costs.
- Conditions
- Physical Activity, Biological Aging, Frail Older Adults, Controlled Clinical Trials, Randomized
- Trial name
- SitLESS (NCT02629666)
- Testing
- ERS and/or Self-management Strategies
- Where
- Spain
- Volunteers
- 1,360 people, healthy volunteers welcome
- Sponsor
- University Ramon Llull
Older Adults (60 - 85 Years Old)
Gymnastics and Multicomponent Training Intervention in Community-dwelling Older Adults
Introduction: Extension projects focused on physical activity can offer health practices and promote quality of life for participants of different ages.
- Trial name
- NCT07766954
- Testing
- Multicomponent training intervention Multicomponent training intervention - Protocol includes mobility, resistance exercises for the lower and upper limbs and major muscle groups, and aerobic exercise
- Where
- Brazil
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Federal University of the Valleys of Jequitinhonha and Mucuri
Aging, Exercise
Regulation of Endothelial Progenitor Cells by Short-Term Exercise
Endothelial Progenitor Cells (EPCs) are circulating cells released from bone marrow which are important for maintaining cardiovascular health.
- Conditions
- Aging, Exercise, Cardiovascular Disease
- Trial name
- EPC-Ex (NCT01169831)
- Testing
- Exercise Training, Exercise Cessation
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Baltimore VA Medical Center
Quality of Life, Aging
Upper Versus Lower Body Resistance Exercise in Older Adults
TITLE: Relation between focused resistance training and its effect on cognitive performance and functional Independence of institutionalized elderly.
- Trial name
- NCT03831373
- Testing
- Physical exercise
- Where
- Spain
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- University of Vigo
Exercise, Self Efficacy
Social Media Chatbot on Physical Activity Education for Older Adults
In this study, a social media chatbot was used to provide a continuous and real-time multimedia health education program on physical activity for the older adults, as well as supportive messages and feedbacks, to improve physical…
- Conditions
- Exercise, Self Efficacy, Behavioral Regulation, Healthy Aging
- Trial name
- NCT06423040
- Testing
- Social Media Chatbot on Physical Activity Education
- Where
- Taiwan
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Taipei Medical University
Obesity, Physical Inactivity
Age and Insulin Resistance
Insulin resistance is a crucial factor for the development of type 2 diabetes and a major health problem for older adults. It is the principal mechanism by which obesity is considered to increase the risk for type 2 diabetes and…
- Conditions
- Obesity, Physical Inactivity, Aging
- Trial name
- AGIR (NCT01224886)
- Testing
- Physical activity
- Where
- 2 sites in Switzerland
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of Lausanne
Skin Aging
Tolerance and Efficacy Evaluation of 3 Face Creams
The study will evaluate the tolerance and the efficacy on skin comfort of F#1048-082 soothing cream used just after injection procedure and also the tolerance and the efficacy of the F#841-020 anti-age cream on aging parameters…
- Trial name
- FILLER (NCT02063971)
- Testing
- Soothing (formulation number: F#1048-082) and antiaging creams (F#841-020 and F#1374-002)
- Where
- Italy
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Adele Sparavigna
Activity, Motor, Health Behavior
Mechanism for Exercise to Delay Cardiac Aging
The goal of this clinicaltrial is to assess and compare isokinetic performance, surface electromyography, laboratory parameters, and cardiorespiratory function both before and after engaging in vigorous intermittent lifestyle…
- Trial name
- NCT06031675
- Testing
- Vigorous intermittent lifestyle physical activity
- Where
- China
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Xiao-dong Zhuang
Exercise
Dietary Supplements and Exercise in Aging Adults
The purpose of this study is to determine the effects of food supplements and strength training on appetite, the amount of energy used, and body composition.
- Trial name
- NCT00761553
- Testing
- Dietary supplements with exercise, Dietary supplement without exercise
- Where
- United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Purdue University
Mobility Limitation
BAILA: Being Active, Increasing Latinos Healthy Aging
Investigators propose a randomized controlled trial (RCT) to test the efficacy of the revised 4-month BAILAMOS© program for improving lifestyle PA and health outcomes (physical and cognitive function, self-reported functional…
- Trial name
- BAILA (NCT01988233)
- Testing
- BAILAMOS© Dance Program, Health Education Control Group
- Where
- 12 sites in United States
- Volunteers
- 333 people, healthy volunteers welcome
- Sponsor
- University of Illinois Chicago
Aging
Energy Expenditure Responses to Acute Exercise in Older Women (Calorie Expenditure and Exercise)
In older, normal-weight women (60-75 yrs, BMI=18-28 kg/m2), an acute bout of higher-intensity (60% of maximum effort) aerobic exercise, in comparison to an isocaloric bout of lower-intensity (45% of maximum effort) exercise…
- Trial name
- CEE (NCT00988299)
- Testing
- exercise
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Fall Risk, Exercise
Effects of Regular Exercise on Sensory-motor Functions and Fall Risk in the Elderly
Falls in elderly population are an important public health problem. The aim of this study is to examine the vibration, proprioception, muscle strength, static balance, reaction time and postural stability parameters of female…
- Conditions
- Fall Risk, Exercise, Functional Outcomes, Aging
- Trial name
- FallRisk (NCT06891014)
- Testing
- Combine Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Cyprus International University
Metformin, Prediabetes
Metformin and Molecular Aging in Prediabetes
The incidence and prevalence of type 2 diabetes mellitus (T2DM) are increasing globally. The global prevalence of diabetes has nearly doubled since 1980, rising from 4.7% to 8.5% in the adult population.
- Trial name
- NCT07302932
- Testing
- Metformin treatment, Analyzed by qPCR for T/S ratio.
- Where
- India
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Diabetes Foundation, India
Aging
Effects of Two Types of Concurrent Training in Functional Performance and Cognitive Function of Older Adults
The goal of this randomized controlled clinical trial is to identify and compare the impacts of traditional concurrent training and concurrent training consisting of strength training combined with dance classes on functional…
- Trial name
- NCT05859243
- Testing
- Traditional concurrent training, Concurrent training consisting of strength training combined with dance classes
- Where
- Brazil
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Eduardo Lusa Cadore
Urinary Incontinence
Functional Assessment and Muscle Evaluation Through Exercise Trial
The purpose of this study is to decrease rates of urinary incontinence in older women by building strength in the pelvic and lower body muscle through exercise and rehabilitation.
- Trial name
- FAME (NCT03166150)
- Testing
- Multi-modal rehabilitation program, Pelvic Floor Physical therapy
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Howard University
Sedentary Lifestyle
Exercise Effects on Brain Health and Learning From Minutes to Months
Given the accelerating growth of older adults worldwide and the decline in cognitive function with aging, therapeutics that remediate age-related cognitive decline are needed more than ever.
- Trial name
- EXTEND (NCT03114150)
- Testing
- Cardiorespiratory fitness training, Functional fitness training
- Where
- United States
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- Michelle W. Voss
Loneliness, Ageing
Physical Activity Intervention for Loneliness
The purpose of this study will be to examine the feasibility of a Physical Activity Intervention for Loneliness (PAIL) in community-dwelling older adults.
- Conditions
- Loneliness, Ageing, Physical Activity
- Trial name
- PAIL (NCT03458793)
- Testing
- Group walking and group educational workshops
- Where
- United Kingdom
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of Birmingham
Aging, Healthy
ACTIVE: Advanced Cognitive Training for Independent and Vital Elderly
The purpose of the ACTIVE study was to test if cognitive training interventions could maintain functional independence in elders by improving basic mental abilities, with follow-up assessments through five years.
- Trial name
- ACTIVE (NCT00298558)
- Testing
- Cognitive Training
- Where
- 7 sites in United States
- Volunteers
- 2,832 people, healthy volunteers welcome
- Sponsor
- Carelon Research
Aging, Obesity
Obesity and Aging: Impacts of Nutritional Counseling and Physical Exercise on Telomeres and Senescence Parameters
The study will involve 80 elderly women, 40 eutrophic and 40 obese, divided into four groups, each with n=20. 1) Eutrophic Group (EG) undergoing only nutritional counseling (NC), 2) Eutrophic Group with NC and combined training…
- Conditions
- Aging, Obesity, Nutrition, Exercise
- Trial name
- NCT07479940
- Testing
- Combined Training, Nutritional Counseling
- Where
- Brazil
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Inactivity, Physical, Aging
Impact of Postprandial 'Exercise Snacks' on Protein and Glucose Metabolism Following a Period of Step Reduction in Older Adults
The purpose of this study is to assess the impact of 3-days reduced physical activity (<1500 steps/day) with/without 'exercise snacks' (15 chair stands with calf raises every 30 min) on skeletal muscle metabolic health.
- Conditions
- Inactivity, Physical, Aging, Healthy Aging, Sarcopenia
- Trial name
- NCT05810272
- Testing
- Metabolic Trial, 15 sit-to-stands with calf raises
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Toronto