Clinical trials: Active Control
Pregnancy, Excessive Weight Gain
Effect of Regular Exercise in Prevention of Excessive Weight Gain in Pregnancy
Background: Use of variable definitions of exercise and disparate results, emphasize the need of proper randomized controlled trials examining the relationship between physical activity and weight development during pregnancy.
- Trial name
- NCT00617149
- Testing
- Supervised exercise for the prevention high weight gain
- Where
- Norway
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Norwegian School of Sport Sciences
Pain
Transcutaneous Electrical Nerve Stimulation for Pain Relief During the Active Phase of Labor
The objective of this research is to evaluate the effectiveness of Transcutaneous Electrical Nerve Stimulation (TENS) for pain relief in the early active phase of labor.
- Trial name
- NCT01600495
- Testing
- Experimental TENS
- Where
- Brazil
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Intact Cord Placental Delivery, Delayed Cord Clamping
Intact Cord Placental Delivery vs Delayed Cord Clamping
The management of the third stage of labour plays a critical role in neonatal transition. Uninterrupted Intact Cord Clamping (UICC), is a clinical approach where the umbilical cord remains unclamped until the placenta is…
- Conditions
- Intact Cord Placental Delivery, Delayed Cord Clamping, Standard Delayed Cord Clamping, Timing of Cord Clamping
- Trial name
- TTC (NCT07713277)
- Where
- Italy
- Volunteers
- 1,979 people, healthy volunteers welcome
- Sponsor
- Azienda ULSS 8 Berica
Healthy
Evaluation of Safety, Pharmacokinetics and Pharmacodynamics of EXPAREL® Administered Via a Single Intrathecal Injection to Healthy Volunteers
Primary objective: To assess the safety and tolerability of EXPAREL® administered as a single intrathecal injection in healthy volunteers Secondary objective: To characterize the pharmacokinetic (PK) and pharmacodynamic (PD)…
- Trial name
- NCT04173611
- Testing
- EXPAREL, Bupivacaine Hydrochloride
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Pacira Pharmaceuticals, Inc
Dengue
An Evaluation of Repeated Oral Doses of JNJ-64281802 Against DENV-3 Challenge
The investigational study drug, JNJ-64281802, is being developed for the prevention and treatment of dengue infection. This study is hypothesizing that the highest dose of the investigational study drug is superior to receiving a…
- Trial name
- NCT05048875
- Testing
- Cohort 1 - Group 1 JNJ High Dose, Cohort 1 - Group 2 JNJ Medium Dose, Cohort 1 - Group 2 JNJ Low Dose
- Where
- 2 sites in United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Physical Activity
A Randomized-controlled Trial of Social Norm Interventions to Increase Physical Activity
Objective: Physical activity confers numerous health benefits, yet few adults meet recommended physical activity guidelines. The impact of brief messages providing feedback on physical activity was tested in this study.
- Trial name
- NCT02710201
- Testing
- Descriptive Social Norm, Descriptive-plus-Injunctive Social Norm
- Volunteers
- 111 people, healthy volunteers welcome
- Sponsor
- University of California, Merced
Pregnancy
Educational Program on Exercise During Pregnancy
This study aims to evaluate whether a short educational session about safe therapeutic exercise during pregnancy can improve knowledge, confidence, and physical activity levels in pregnant women.
- Trial name
- EDUPREG (NCT07486999)
- Testing
- Educational Session on Therapeutic Exercise During Pregnancy
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Oviedo
Primary Dysmenorrhea
The Effect of Kegel Exercise in Nursing Students With Primary Dysmenorrhoea
In this study, it was aimed to determine the effect of kegel exercise on menstruation symptoms, severity of dysmenorrheic symptoms and quality of life in nursing students with primary dysmenorrhea.
- Trial name
- NCT06225102
- Testing
- Kegel Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- Gümüşhane Universıty
Anorexia Nervosa
Active Lifestyle Intervention in Anorexia Nervosa: a Comprehensive Study
The goal of this study is to perform a comprehensive analysis of varied health markers and analyze the impact of lifestyle interventions on the prognosis of anorexia nervosa (AN) patients.
- Trial name
- DiANa (NCT06866301)
- Testing
- Progressive Resistance Exercise
- Where
- Spain
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University of Oviedo
Tuberculosis, Tuberculosis, Pulmonary
Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Ex-vivo Antitubercular Activity of PBTZ169 Formulation
This is a randomized, double-blind, placebo-controlled, single ascending dose study conducted at one study center in Switzerland.
- Trial name
- NCT03423030
- Testing
- PBTZ169 Formulation, PBTZ169 NCP
- Where
- Switzerland
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Innovative Medicines for Tuberculosis
Pneumococcal Infections
A Study to Evaluate the Safety, Tolerability, and Immunogenicity of V114 Followed by PNEUMOVAX™23 in Healthy Adults 50 Years of Age or Older (V114-016/PNEU-PATH)
This study is designed 1) to evaluate the safety, tolerability, and immunogenicity of V114 and Prevnar 13™, 2) to describe the safety of sequential administration of V114 or Prevnar 13™ followed by PNEUMOVAX™23, and 3) to…
- Trial name
- PNEU-PATH (NCT03480763)
- Testing
- V114, Prevnar 13™, PNEUMOVAX™23
- Where
- 22 sites in United States, South Korea and 2 more
- Volunteers
- 652 people, healthy volunteers welcome
- Sponsor
- Merck Sharp & Dohme LLC
Influenza
A Multicenter, Double-blind, Parallel, Non-inferiority, Phase III Study
A Multicenter, Randomized, Double-blind, Active-controlled, Parallel, Non-inferiority, Phase III Study.
- Trial name
- NCT02658409
- Testing
- GC3106(quadrivalent cell-culture based influenza vaccine), Fluarix™tetra Syringe Inj.(quadrivalent influenza vaccine)
- Where
- South Korea
- Volunteers
- 1,630 people, healthy volunteers welcome
- Sponsor
- Green Cross Corporation
Physical Inactivity
Active Moms Project: Physical Activity Intervention for Low-Income Mothers
Despite the health benefits of physical activity, increasing regular physical activity levels among low-income, ethnic-minority mothers has remained a significant challenge.
- Trial name
- NCT05540509
- Testing
- Community-based intervention, Home-based intervention
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- California State University, Long Beach
Healthy Participants
Novel Energy Metabolic Signaling Molecule With Therapeutic Potential
Altogether a 25-day study. First 4 days non-blinded with water before 0-control blood samples (Day0). Thereafter blinded for 21 days (3 weeks). Study group was apparently healthy 50-60 -year-old males and females (N=27).
- Trial name
- RH013001 (NCT04713319)
- Testing
- Panavital
- Where
- Finland
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Petteri Hirvonen
Hepatitis A Vaccine
To Evaluate the Immunogenicity and Safety of Inactivated Hepatitis A Vaccine
The purpose of this study is to evaluate the immunogenicity and safety after one primary dose and one additional dose of inactivated hepatitis A vaccine are administered in Korean healthy children aged 12-23 months.
- Trial name
- VITHA-C (NCT03654664)
- Testing
- Inactivated hepatitis A vaccine, Havrix Inj
- Where
- 10 sites in South Korea
- Volunteers
- 119 people, healthy volunteers welcome
- Sponsor
- Boryung Pharmaceutical Co., Ltd
HIV
Behavioral Activation and Risk Reduction for Stimulant Use Among Sexually Active Adolescents and Young Adults
The use of behavioral intervention to reduce stimulant use and concurrent HIV sexual transmission risk.
- Trial name
- IMPACT (NCT06444360)
- Testing
- IMPACT, eSOC
- Where
- 2 sites in United States
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- Westat
Cerebral Concussion
Acute Concussion Therapy Intervention Training in Healthy and Concussed Participants
Healthy (non-injured) and concussed college-aged participants will complete two testing sessions that include (1) clinical symptom, balance, and cognitive evaluations and (2) a progressive exercise session to establish symptom…
- Trial name
- ACTIVE (NCT02872480)
- Testing
- ACTIVE Training
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Human Immunodeficiency Virus (HIV), HIV Pre-Exposure Prophylaxis
A Clinical Study of MK-8527 to Prevent Human Immunodeficiency Virus Type 1 (HIV-1) (MK-8527-011)
Researchers are looking for new medicines to prevent HIV-1 (Human Immunodeficiency Virus Type 1) infection. The goals of this study are to learn: If taking MK-8527 once a month works to prevent HIV-1 infection as well as or…
- Trial name
- NCT07044297
- Testing
- MK-8527, FTC/TDF
- Where
- 81 sites in United States, Argentina and 14 more
- Volunteers
- 4,390 people, healthy volunteers welcome
- Sponsor
- Merck Sharp & Dohme LLC
Active Root Caries, Over Sixty-five Years of Age
Treatment of Root Caries in an Older Irish Population.
This study will involve filling teeth which have decay on their roots with three different filling materials. Patients will attend Cork University Dental School and hospital for a clinical examination and to complete a…
- Conditions
- Active Root Caries, Over Sixty-five Years of Age, >=Two Carious Root Surfaces Per Patient
- Trial name
- NCT01866059
- Testing
- Calcium silicate cement, Glass Ionomer Cement, Resin Modified Glass Ionomer Cement
- Where
- Ireland
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- University College Cork
Physical Activity, Child
Arkansas Active Kids! -Objective 3
This is a cross-sectional study aiming to identify how daily activities affect children's body fitness and general health. Also, the study will address how specific behaviors (such as diet and sleep) as well as neighborhood and…
- Trial name
- AAK (NCT03221673)
- Where
- United States
- Volunteers
- 230 people, healthy volunteers welcome
- Sponsor
- Arkansas Children's Hospital Research Institute