Clinical trials: Activities, Motor
Agitation in Adolescents and Young Adults With ASD
INP105 Proof-of-concept Study for the Acute Treatment of Agitation in Adolescents and Young Adults With ASD
This is a Phase 2a, proof-of concept, 2-way, 2-period crossover, double-blind study to evaluate the safety and efficacy of INP105 as an acute treatment versus placebo in adolescents and young adults with autism spectrum disorder…
- Trial name
- CALM 201 (NCT05163717)
- Testing
- INP105
- Where
- 2 sites in United States
- Volunteers
- 8 people
- Sponsor
- Impel Pharmaceuticals
Gastrointestinal Microbiome, Nutrition, Healthy
The Effects of a Novel Nutritional Product on Nutrient Gaps and Gut Health in Active Adults
This study is a randomized, double-blind, placebo-controlled study of N=20 active men and women. This study to assess the effect of a novel dietary supplement on improving nutrient gaps and the gut microbiome.
- Conditions
- Gastrointestinal Microbiome, Nutrition, Healthy, Exercise
- Trial name
- NCT06521424
- Testing
- AG1 - Nutritional Supplement
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Athletic Greens International
Agitation, Alzheimer Disease
Study to Evaluate the Efficacy, Safety, and Tolerability of BMS-986368, for the Treatment of Agitation in Participants With Alzheimer's Disease
This is a study to evaluate the efficacy, safety, and tolerability of BMS-986368, a FAAH/MAGL inhibitor, for the treatment of agitation in participants with Alzheimer's Disease.
- Trial name
- NCT06808984
- Testing
- BMS-986368
- Where
- 77 sites in United States, Argentina and 2 more
- Volunteers
- 120 people
- Sponsor
- Celgene
Agitation Associated With Alzheimer's Dementia, Alzheimer Dementia
A Trial to Evaluate the Safety, Efficacy, and Tolerability of Brexpiprazole in Treating Agitation Associated With Dementia of the Alzheimer's Type
This study compares the efficacy of 2 doses of brexpiprazole with placebo in participants with agitation associated with dementia of the Alzheimer's type.
- Trial name
- NCT03548584
- Testing
- Brexpiprazole
- Where
- United States
- Volunteers
- 345 people
- Sponsor
- Otsuka Pharmaceutical Development & Commercialization, Inc.
Pre-diabetes
Evaluation of Video On-Demand Programming to Prevent Type 2 Diabetes in Adults
Over the past 40 years, diabetes has increased dramatically in parallel with rapid increases in obesity.About 90 to 95% of persons with diabetes have type 2 diabetes, which begins when the body becomes resistant to the hormone…
- Trial name
- Project NOT ME (NCT01768546)
- Testing
- Virtual Diabetes Prevention Program, Interactive tracking and problem solving web portal
- Volunteers
- 306 people
- Sponsor
- UnitedHealth Group
Chronic Kidney Disease, Renal Failure Chronic Requiring Hemodialysis
Specific Enteral Nutrition in Malnourished, Dialysis Patients With Chronic Kidney Disease. Efficacy, Safety, Quality of Life
The objective of this unblinded study is to assess the nutritional effects of a 12 weeks administration of the specific enteral nutrition (SEN) RealDiet®Renal pockets, as well as the impact on the patients' quality of life.
- Conditions
- Chronic Kidney Disease, Renal Failure Chronic Requiring Hemodialysis, Severe Malnutrition, Tolerance
- Trial name
- AL-EN-PHED (NCT01946841)
- Testing
- RealDiet®Renal
- Where
- France
- Sponsor
- Lactalis
Exercise-Induced Asthma
Study of Oglemilast for the Prevention of Asthma.
The purpose of this study is to determine whether it is effective in the treatment of exercise-induced asthma and investigate the safety of oglemilast.
- Trial name
- NCT00322283
- Testing
- Oglemilast
- Where
- 2 sites in United States
- Volunteers
- 24 people
- Sponsor
- Forest Laboratories
Cystic Fibrosis
A Study to Evaluate ELX/TEZ/IVA on Cough and Physical Activity in Participants With Cystic Fibrosis (CF)
This study will evaluate the effects of elexacaftor/tezacaftor/ivacaftor (ELX/TEZ/IVA) on cough and physical activity using wearable technology in CF participants.
- Trial name
- NCT04969224
- Testing
- ELX/TEZ/IVA, IVA
- Where
- 19 sites in Australia, Belgium and 2 more
- Volunteers
- 82 people
- Sponsor
- Vertex Pharmaceuticals Incorporated
Type 2 Diabetes Treated With Insulin
Lifestyle Intervention in Type 2 Diabetes
The purpose of the study is to determine whether a personalized lifestyle intervention focused on diet and physical activity reinforcement is effective in avoiding weight gain in the first months following initiation of…
- Trial name
- WeightPump (NCT02791295)
- Testing
- Diet and physical activity program
- Where
- 6 sites in France
- Volunteers
- 54 people
- Sponsor
- Icadom
Physical Inactivity, Psychological Well-Being
VR Exercise Intervention in a Workplace Setting
This research study is designed to better understand how a virtual reality (VR) exercise application may influence overall physical activity and well-being.
- Conditions
- Physical Inactivity, Psychological Well-Being, Work-Related Stress
- Trial name
- VRW (NCT06416839)
- Testing
- VR exercise
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- XRWorkout, Inc
Delayed Onset Muscle Soreness, DOMS
COMBOPROFEN for Treatment of Muscular Pain Associated With Delayed Onset Muscle Soreness (DOMS)
The study is designed as a proof of concept, single-center, randomized, double-blind, placebo controlled study to assess the safety and efficacy of Comboprofen (Ibuprofen + Magnesium + Vitamin C) compared to placebo, Ibuprofen…
- Trial name
- NCT03223519
- Testing
- Comboprofen, Ibuprofen, Magnesium
- Where
- Spain
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Spherium Biomed
Exercise, Health Behavior
Physical Activity Smartphone App for African American Men (FitBros) Phase I
Low physical activity levels contribute to African American men experiencing health disparities across a number of chronic diseases.
- Conditions
- Exercise, Health Behavior, Technology
- Trial name
- FitBros (NCT05509712)
- Testing
- Focus Groups to Refine MobileMen App Content, Beta testing of MobileMen App Prototype
- Where
- 3 sites in United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Klein Buendel, Inc.
Exercise
A Study to See if an Energy Drink With Caffeine and Green Tea Increases Fat Burning When Exercising
The goal of this study is to evaluate the influence of consuming a drink containing a combination of caffeine and green tea extracts on fat oxidation responses at rest, during and after a period of endurance type exercise.
- Trial name
- NCT07434752
- Testing
- Active (Green tea and caffeine)
- Where
- Australia
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- RDC Clinical Pty Ltd
Health Services Accessibility, First-line Treatment
Can Digitally Delivered First-line Osteoarthritis Treatment Improve Equal Access to Care
To improve chronically ill patients' health and quality of life, long-standing and continuous treatment is needed at an acceptable cost.
- Conditions
- Health Services Accessibility, First-line Treatment, Osteoarthritis
- Trial name
- Access (NCT06148779)
- Testing
- Digitally delivered first-line treatment for osteoarthritis, Face-to-face first-line treatment for osteoarthritis
- Where
- Sweden
- Volunteers
- 50,000 people
- Sponsor
- Joint Academy
Fluid Intake in Athletes, Sweating Rate in Athletes
Validity of Smart Cap and Smart Sweat Patch
The main objectives are to determine the validity of a Smart Cap in measuring fluid intake during running and fitness exercise and the validity of a Smart Sweat Patch in measuring sweat rate and sweat chloride concentration…
- Conditions
- Fluid Intake in Athletes, Sweating Rate in Athletes, Sweat Chloride Concentration in Athletes
- Trial name
- NCT04920266
- Testing
- Smart Cap, running and fitness exercisers only, Sweat Patch, all subjects- running, fitness, cycling, Reference sweat patch, all subjects - running, fitness, cycling
- Where
- 3 sites in United States
- Volunteers
- 173 people, healthy volunteers welcome
- Sponsor
- PepsiCo Global R&D
Agitation in Patients With Dementia of the Alzheimer's Type
Study to Assess the Efficacy, Safety, and Tolerability of AVP-786 for the Treatment of Agitation in Patients With Dementia of the Alzheimer's Type
This study was conducted to evaluate the efficacy, safety, and tolerability of AVP-786 (deudextromethorphan hydrobromide [d6-DM]/quinidine sulfate [Q]) compared to placebo for the treatment of agitation in participants with…
- Trial name
- NCT04464564
- Testing
- AVP-786
- Where
- 106 sites in United States, Belgium and 11 more
- Volunteers
- 241 people
- Sponsor
- Otsuka Pharmaceutical Development & Commercialization, Inc.
Alzheimer Disease, Agitation,Psychomotor
Clinical Trial on Agitation in Alzheimer's Dementia
The purpose of this study is to assess the efficacy of the oral medication IGC-AD1, a THC-based (Delta-9-Tetrahydrocannabinol) formulation administered twice a day on Agitation in patients with mild to severe dementia from…
- Conditions
- Alzheimer Disease, Agitation,Psychomotor, Care Giving Burden, NPS
- Trial name
- CALMA (NCT05543681)
- Testing
- IGC-AD1-Active
- Where
- 28 sites in United States, Canada and 1 more
- Volunteers
- 164 people
- Sponsor
- IGC Pharma, LLC
Cystic Fibrosis
A Decentralized Study to Evaluate Physical Activity and Cough Frequency Using Wearable Technology in Cystic Fibrosis
This study will evaluate the performance of wearable technology in cystic fibrosis (CF) participants taking commercial Elexacaftor (ELX)/Tezacaftor (TEZ)/Ivacaftor (IVA) utilizing a fully decentralized trial design.
- Trial name
- NCT04923464
- Where
- 17 sites in United States, United Kingdom
- Volunteers
- 51 people
- Sponsor
- Vertex Pharmaceuticals Incorporated
Rheumatoid Arthritis
Physical Activity in Patients With Rheumatoid Arthritis Treated With Adalimumab in Routine Clinical Practice
The purpose of this study was to evaluate physical activity and its changes in participants with rheumatoid arthritis (RA) who were treated with adalimumab therapy in clinical practice.
- Trial name
- PACE (NCT01756235)
- Volunteers
- 462 people
- Sponsor
- AbbVie (prior sponsor, Abbott)
Physical Inactivity, Oxygen Consumption
Gentle Jogger and Oxygen Consumption
This is a non randomized study to determine the effects of Gentle Jogger(GJ), a passive jogging device on oxygen consumption in 2 postures supine and seated.
- Trial name
- NCT03602365
- Testing
- Gentle Jogger (GJ)
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Sackner Wellness Products LLC