Clinical trials: Acute ACE-induced Angioedema
ACE Inhibitor Induced Angioedema
Evaluation of Ecallantide for Treatment of Angiotensin Converting Enzyme (ACE) Inhibitor Induced Angioedema
A double-blind, randomized, controlled trial comparing the safety and effectiveness of conventional therapy with ecallantide to conventional therapy with placebo.
- Trial name
- NCT01343823
- Testing
- ecallantide 60 mg, ecallantide 30 mg, ecallantide 10 mg
- Where
- 39 sites in United States
- Volunteers
- 79 people
- Sponsor
- Shire
Acute ACE-induced Angioedema
Randomized, Double-blind, Two Arms, Multicenter, Phase III Study of Berinert for Treatment of ACE Induced Angioedema
This trial is a randomized, double-blind, two arms, multicenter, Phase III study of Berinert for treatment of ACE induced Angioedema.
- Trial name
- NCT01843530
- Testing
- Berinert, Clemastin, Cortisone acetate
- Where
- 4 sites in Germany
- Volunteers
- 31 people
- Sponsor
- Technical University of Munich
Angioedema
Evaluation of Ecallantide for the Acute Treatment of Angiotensin Converting Enzyme Inhibitor Induced Angioedema
The investigators will conduct a double-blind, randomized controlled trial comparing the safety and effectiveness of ecallantide to conventional therapy.
- Trial name
- ACE (NCT01036659)
- Testing
- ecallantide - Kallikrein inhibitor that blocks the production of bradykinin
- Where
- 3 sites in United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Bernstein, Jonathan A., M.D.