Clinical trials: Acute Asthma Exacerbation
Asthma
Web-Based and Tailored Asthma Management Intervention (Puff City) in Teens With Asthma Attending Urban Clinics
The purpose of this study is to evaluate the Puff City web-based behavioral intervention of asthma management program in a clinical setting.
- Trial name
- PCC (NCT01757002)
- Testing
- Teens randomized to the experimental arm will receive 4 sessions plus a booster of web-based, tailored asthma management., Teens in the control group will receive generic, web-based asthma education.
- Where
- United States
- Volunteers
- 266 people
- Sponsor
- Henry Ford Health System
Status Asthmaticus, Asthma (Diagnosis)
IV DEXAMETHASONE VS. METHYLPREDNISOLONE IN CHILDREN WITH SEVERE ASTHMA EXACERBATION
The study aims to determine whether a two-day intravenous course of dexamethasone is non-inferior to a conventional five-day intravenous course of methylprednisolone in children presenting with severe asthma exacerbations.
- Conditions
- Status Asthmaticus, Asthma (Diagnosis), Asthma Exacerbations
- Trial name
- IV:INTRAVENOUS (NCT07731217)
- Testing
- Intravenous Dexamethasone, Intravenous Methylprednisolone
- Where
- Turkey (Türkiye)
- Volunteers
- 129 people
- Sponsor
- Istanbul Medeniyet University
Acute Asthma
Magnesium Nebulization Utilization in Management of Pediatric Asthma
Acute asthma is the most common cause of pediatric hospitalizations. While the investigators know that repeat inhalations of ß2 agonists and ipratropium with early oral steroids substantially reduce hospitalizations, many…
- Trial name
- MAGNUMPA (NCT01429415)
- Testing
- Magnesium Sulfate Sandoz, Sodium Chloride , USP PPC
- Where
- 7 sites in Canada
- Volunteers
- 818 people
- Sponsor
- The Hospital for Sick Children
Asthma Attack, Asthma Control
Boosting Referrals to Asthma Specialists for Patients Seen at the Emergency Room for an Asthma Exacerbation
This study is testing a new way to help adults with asthma get follow up care after an emergency room (ER) visit for an asthma attack.
- Conditions
- Asthma Attack, Asthma Control, Asthma Exacerbations, Asthma
- Trial name
- NCT07396987
- Testing
- ER-Initiated Telehealth Referral
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Juan Carlos Cardet
Acute Exacerbation of Asthma
Dexamethasone Versus Prednisolone in Acute Exacerbation of Childhood Asthma
Because of insufficient local comparative data, this study was designed to determine the outcome of intravenous dexamethasone in contrast to oral prednisolone in acute exacerbation of asthmatic children.
- Trial name
- NCT07275593
- Testing
- Dexamethasone, Prednisolone
- Where
- Pakistan
- Volunteers
- 224 people
- Sponsor
- Muhammad Aamir Latif
Asthma
Dexamethasone Tolerability in the Treatment of Acute Asthma in Children
The purpose of this study is to assess whether smaller volumes of oral dexamethasone result in better tolerability, specifically less vomiting, in pediatric patients during an acute asthma exacerbation.
- Trial name
- NCT00973687
- Testing
- Ora Sweet, Dexamethasone
- Where
- Canada
- Volunteers
- 430 people
- Sponsor
- IWK Health Centre
Severe Asthma
Tezepelumab in the Treatment of Emergency Room Asthma in Adults (TERAA)
Adults with severe asthma may have sudden worsening shortness of breath that results in their going to Emergency Department for urgent care.
- Trial name
- TERAA (NCT06705764)
- Testing
- Tezepelumab
- Where
- 2 sites in Canada
- Volunteers
- 100 people
- Sponsor
- University of Alberta
Asthma in Children
Comparasion of Efficacy of Nebulized With Intravenous Magnesium Sulphate in Children With Asthma
The purpose of study is to assess the effectiveness of nebulized magnesium sulphate in children presenting with acute asthma.Study perfoma consists of demographic variables,exclusion criteria and pediatric asthma score that…
- Trial name
- NCT04497766
- Testing
- Nebulized Magnesium sulfate, Intravenous magnesium sulphate
- Where
- Pakistan
- Volunteers
- 148 people
- Sponsor
- Saima Khatoon
Asthma Exacerbation
Pilot Study of How Children With Asthma Exacerbations Metabolize Prednisone
The objective of the investigators pilot study is to assess the pharmacokinetic profile of two corticosteroid drugs, prednisone and prednisolone, in children who present to the pediatric emergency department with an asthma…
- Trial name
- NCT01260623
- Testing
- Prednisolone and prednisone
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Moderate Acute Asthma
Nebulized Procaterol Versus Nebule Salbutamol for the Treatment of Moderate Acute Asthma
The purpose of this study is to compare the efficacy and safety of nebule procaterol with nebule salbutamol in the treatment of moderate acute asthma.
- Trial name
- NCT00990847
- Testing
- Procaterol, Salbultamol
- Where
- Indonesia
- Volunteers
- 140 people
- Sponsor
- PT Otsuka Indonesia
Asthma Acute, Asthma in Children
Non-invasive Ventilation vs. Standard Therapy for Children Hospitalized With an Acute Exacerbation of Asthma
Acute asthma produces greatly increased work of breathing and increased oxygen requirement secondary to bronchial narrowing and airway obstruction by inflammatory secretions.
- Trial name
- NCT03296579
- Testing
- BiPAP, CPAP, Ipratropium
- Volunteers
- 100 people
- Sponsor
- University of British Columbia
Asthma
Examining Changes in Nasal IL-1 During Acute Asthma Exacerbation in Adolescents
To study the change from baseline in IL-1β (interleukin 1 beta) concentrations in the nasal airway during acute asthma exacerbation, specifically to measure the degree of change and identify the timing of peak IL-1β…
- Trial name
- Attack Asthma (NCT04748055)
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of North Carolina, Chapel Hill
Asthma Exacerbation, Quality of Life
Application of Telehealth Technology in Asthma Management
Background: While effective treatments are available, asthma control is sub-optimal for many asthma patients. To help patients self-manage their asthma symptoms, provision of an asthma action plan (AAP) in written format (wAAP)…
- Conditions
- Asthma Exacerbation, Quality of Life, Medication Adherence
- Trial name
- NCT05484037
- Testing
- CANATEXTS
- Where
- 3 sites in Canada
- Volunteers
- 620 people
- Sponsor
- University of British Columbia
Asthma, Asthma Attack
Remote Patient Monitoring Solution for Chronic Respiratory Disease Management
Aim: To evaluate the use of AeviceMD Monitoring System (AeviceMD) asthma in reducing acute exacerbation. Methodology: Using a randomized controlled trial design, this project aims evaluate the effectiveness of AeviceMD in…
- Conditions
- Asthma, Asthma Attack, Asthma in Children, Asthma Acute
- Trial name
- NCT06377345
- Testing
- AeviceMD device, Standard care
- Where
- Singapore
- Volunteers
- 180 people
- Sponsor
- SingHealth Polyclinics
Asthma
The Predictors for Asthma Control by Stepwise Treatment During 6 Months in Korean Elderly
The Predictors for asthma control by stepwise treatment during 6 months in Korean elderly
- Trial name
- Prelude (NCT01370577)
- Where
- 5 sites in South Korea
- Volunteers
- 297 people
- Sponsor
- AstraZeneca
Asthma
Intramuscular Epinephrine as an Adjunctive Treatment for Severe Pediatric Asthma Exacerbation
Project Aim: To determine if intramuscular epinephrine is an effective adjunct to inhaled bronchodilators (β2 agonists) for children with severe asthma exacerbation.
- Trial name
- NCT01705964
- Testing
- IM epinephrine 1:1000, No intervention
- Where
- United States
- Volunteers
- 49 people
- Sponsor
- University of Louisville
Asthma-COPD Overlap
Efficiency of Budesonide Combined With Formoterol and Tiotropium in the Treatment of Acute Exacerbation of ACO
This study evaluates the efficiency of ICS(budesonide) combined with LABA (formoterol) and LAMA(tiotropium) in the treatment of acute exacerbation of asthma-chronic obstructive pulmonary overlap.
- Trial name
- NCT03504527
- Testing
- triple combinations, double combinations
- Volunteers
- 120 people
- Sponsor
- Huashan Hospital
Asthma
Retrospective Review on Patients With Recurrent Asthmatic Attacks Requiring Hospitalizations
Asthma is a common respiratory disease. around the world. Asthma exacerbation is one of the major sequelae and associated with various morbidity and mortality.
- Trial name
- NCT04479501
- Testing
- Asthma exacerbation related hospitalization
- Where
- Hong Kong
- Volunteers
- 2,280 people
- Sponsor
- Chinese University of Hong Kong
Asthma
Eicosanoid Lipids by Airway Cells During Infection With Human Rhinoviruses
The long-range goal of this protocol is to more completely understand the risks and the pathophysiology of asthma exacerbations, in order to develop prevention strategies and/or expedite a return to complete control of baseline…
- Trial name
- NCT01898767
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- University of Wisconsin, Madison
Asthma
Comparison of Breath-Enhanced and T-Piece Nebulizers in Children With Acute Asthma
This is a blinded observer randomized controlled trial comparing two nebulizer devices. The objective of this study is to evaluate the efficacy of two different nebulizers.
- Trial name
- NCT02566902
- Testing
- T-Piece Nebulizer, Breath-Enhanced Nebulizer, Albuterol
- Where
- United States
- Volunteers
- 118 people
- Sponsor
- Seton Healthcare Family