Clinical trials: Acute Back Pain
Neck Pain, Low Back Pain
Effectiveness Comparison of Thoracic Thrust Manipulation in People With Neck or Low Back Pain
Objective: To compare the effectiveness of thoracic thrust manipulation, together with massages techniques and stretching, between people with neck pain versus people with low back pain.
- Trial name
- NCT04981574
- Testing
- Massage and stretching on neck area and thoracic thrust manipulation, Massage and stretching on low back area and thoracic thrust manipulation
- Where
- Spain
- Volunteers
- 60 people
- Sponsor
- University of Jaén
Acute Low Back Pain
Efficacy and Safety of NVP-1203 and NVP-1203-R in Patients With Acute Low Back Pain
The purpose of this study is to evaluate the efficacy and safety NVP-1203 in patients with acute low back pain.
- Trial name
- NCT04082975
- Testing
- NVP-1203, NVP-1203-R
- Where
- South Korea
- Volunteers
- 421 people
- Sponsor
- NVP Healthcare
Acute Low Back Pain
A Two-Arm Study Comparing the Analgesic Efficacy and Safety of Acetaminophen and Tramadol Combination BID Versus Placebo for the Treatment of Acute Low Back Pain
A multi-center placebo controlled, double-blind, trial comparing the analgesic efficacy and safety of Acetram Contramid® BID versus placebo for the treatment of acute low back pain in patients between 18 and 80 yrs of age.
- Trial name
- NCT00643383
- Testing
- Combination drug (Acetaminophen + Tramadol)
- Where
- 38 sites in United States, Canada
- Volunteers
- 277 people
- Sponsor
- Labopharm Inc.
Spondylarthritis, Uveitis, Anterior
Observational Prospective Turkish Inception Cohort of Uveitis and Spondyloarthritis
Spondyloarthritis (SpA) encompasses a group of inflammatory rheumatic diseases characterized by axial and/or peripheral arthritis, along with extra-articular manifestations such as enthesitis, dactylitis, uveitis, and skin…
- Trial name
- OPTICUS (NCT06720376)
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Marmara University
Chronic Low Back Pain (CLBP), Acute Low Back Pain
Multimodal Imaging and Biospecimen Collection for Low Back Pain (LBPB)
This prospective cohort study investigates the neurobiological, genetic, and psychosocial mechanisms underlying acute and chronic low back pain (LBP).
- Conditions
- Chronic Low Back Pain (CLBP), Acute Low Back Pain, Low Back Pain, Chronic Pain
- Trial name
- LBPB (NCT06967363)
- Testing
- Nerve Block, endoscopic spinal disecetomy, Medication
- Where
- 2 sites in China
- Volunteers
- 360 people
- Sponsor
- Peking University Third Hospital
Chronic Low-back Pain
Immediate Effects of Two Spinal Manipulative Techniques
The aim of this study is to investigate the instant effects of direct vertabral manipulation and indirect vertebral manipulation techniques on muscles mechanical properties, pressure-pain threshold and joint range of motion in…
- Trial name
- NCT05057091
- Testing
- Group 1 - Maitland's Posterior-Anterior Central Vertebral Manipulation, Group 2- Side-Lying Lumbar Spinal Manipulation
- Where
- Turkey (Türkiye)
- Volunteers
- 46 people
- Sponsor
- Alanya Alaaddin Keykubat University
Low Back Pain
Efficacy of the Combination of Ibuprofen and Paracetamol in Acute Non-specific Low Back Pain
The aim of the present study is to assess the efficacy and safety of paracetamol/ibuprofen Fixed Dose Combination (FDC) compared to ibuprofen in patients with uncomplicated non-specific acute low back pain after a 3-day treatment…
- Trial name
- NCT05222724
- Testing
- Tachifene, Brufen
- Where
- 11 sites in Italy, Poland
- Volunteers
- 176 people
- Sponsor
- Aziende Chimiche Riunite Angelini Francesco S.p.A
Low Back Pain, Physiotherapy
The Direct-Physio Trial
Previous research showed that direct access to physiotherapy, and the associated early physiotherapeutic treatment of patients with low back pain (LBP), results in improved clinical outcomes, as well as reduced health-related…
- Trial name
- NCT05215093
- Testing
- Direct access physiotherapy for acute low back pain, Usual care for acute low back pain
- Where
- Belgium
- Volunteers
- 200 people
- Sponsor
- Hasselt University
Low Back Pain
Characterizing the Role of Pain Sensitivity in Acute to Persistent Low Back Pain
This research study will examine whether enhanced pain sensitivity increases the risk of persistent low back pain. The study will address the highly prevalent and costly condition of persistent low back pain and a major obstacle…
- Trial name
- NCT01981382
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- University of Connecticut
Acute Low Back Pain
Study to Evaluate a Pharmacokinetic Drug Interaction Between Eperisone Hydrochloride and Aceclofenac in Healthy Male Subjects
A randomized, open label, single-dose, 6-sequence, 3-period, crossover study to evaluate a pharmacokinetic drug interaction between eperisone hydrochloride and aceclofenac in healthy male subjects.
- Trial name
- NCT01638286
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Hanmi Pharmaceutical Company Limited
Low Back Pain
Effectiveness of Coordinated Care to Reduce the Prolonged Disability Risk Among Patients Suffering From Low Back Pain in Primary Care
Common low back pain affects about 23% of general population and can be associated with psychosocial difficulties and prolonged inability to work.
- Trial name
- COLOMB (NCT04826757)
- Testing
- Coordinated care
- Where
- 20 sites in France
- Volunteers
- 220 people
- Sponsor
- University Hospital, Angers
Low Back Pain
Efficacy and Safety of Finalgon® Cream Multiple Doses in Acute Low Back Pain
To evaluate efficacy of Finalgon® cream (1.08% Nicoboxil/ 0.17% Nonivamide) versus placebo in patients with acute low back pain.
- Trial name
- NCT02300311
- Testing
- nonivamide + nicoboxil (Finalgon cream)
- Where
- 8 sites in Russia, Ukraine
- Volunteers
- 138 people
- Sponsor
- Boehringer Ingelheim
Acute Low Back Pain
Clinical Pathways and Patients' Attitudes in Acute Low Back Pain
In France the prevalence of low back pain is 70 to 80 %. It's the leading cause of health expenditure in Europe and costs 900 million euros per year to health insurance in France.
- Trial name
- AcuteLBP (NCT04575714)
- Testing
- Data record
- Where
- France
- Volunteers
- 250 people
- Sponsor
- CHU de Reims
Spine Injuries and Disorders
Evaluation of Osteopathic Protocol on Rachialgia, Bis
Rachialgia are among the most common reasons for consultation with the general practitioner in Europe. Most of the guidelines recommend spinal manipulation.
- Trial name
- PO2S (2) (NCT07667426)
- Testing
- Osteopathic Protocol in 2 Sessions (PO2S)
- Where
- New Caledonia
- Volunteers
- 50 people
- Sponsor
- Cabinet d'ostéopathie Michel Boeuf
Modified Radical Mastectomy, Post Operative Pain, Acute
Comparıson of Analgesıc Effıcacy of Dıfferent Volumes of Serratus Posterior Superıor Intercostal Plane Block After Modıfıed Radıcal Mastectomy Surgery
The aim of researchers is to compare the effects of three different local anesthetic concentrations and volumes on opioid consumption, postoperative analgesic efficacy, and pain scores during ultrasound-guided SPSIP blocks in…
- Conditions
- Modified Radical Mastectomy, Post Operative Pain, Acute, Facial Plane Blocks
- Trial name
- NCT07670078
- Testing
- Serratus Posterior Superior Intercostal Plane (SPSIP) block 40 ml of 0.1875% bupivacaine, Serratus Posterior Superior Intercostal Plane (SPSIP) 50 ml of 0.15% bupivacaine, Serratus Posterior Superior Intercostal Plane (SPSIP) 30 ml of 0.25% bupivacaine
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Cumhuriyet University
Low Back Pain
General Exercises With and Without TA Contraction in Patients With Nonspecific Acute LBP
PURPOSE: To evaluate the effectiveness of adding transversus abdominis contraction to general exercises to treat patients with nonspecific acute low back pain.
- Trial name
- NCT05838040
- Testing
- General exercises, General exercises with tranversus abdmoinis contraction
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Ahram Canadian University
Acute Low-back Pain
Efficacy and Safety of Etoricoxib/Cyanocobalamin Versus Etoricoxib for Acute Low Back Pain
Phase III longitudinal, multicenter, randomized, double-blind clinical trial. The aim of this study is to evaluate the efficacy and safety of the Fixed-Dose Combination of Etoricoxib/Cyanocobalamin Versus Etoricoxib in Patients…
- Trial name
- NCT06517823
- Testing
- Etoricoxib + Cyanocobalamin fixed dose, Etoricoxib fixed dose
- Where
- Mexico
- Volunteers
- 190 people
- Sponsor
- Laboratorios Silanes S.A. de C.V.
Low Back Pain
EFFECTIVENESS OF A PROGRAM OF DOMICILIARY EXERCISES AGAINST HABITUAL CLINICAL PRACTICE IN THE RECURRENCE OF ACUTE LOW BACK PAIN: RANDOMIZED CLINICAL TRIAL
Introduction: Low back pain is a frequent and universally distributed symptom that affects people of any age and both sexes. Approximately 80% of the population will present it at some point in their life.
- Trial name
- LUMBAREX (NCT03827486)
- Testing
- Standard of care (exercise), Domicilary exercise program
- Volunteers
- 70 people
- Sponsor
- Hospital San Carlos, Madrid
Breast Cancer, Postoperative Pain
Ultrasound-Guided SPSIP Versus ESPB for Postoperative Pain After Modified Radical Mastectomy
Breast cancer is the most common cancer affecting women worldwide. Modified radical mastectomy is one of the main surgical treatments for breast cancer.
- Conditions
- Breast Cancer, Postoperative Pain, Acute Post-surgical Pain
- Trial name
- SPSIP-ESPB (NCT07446868)
- Testing
- Serratus Posterior Superior Intercostal Plane Block, Erector Spinae Plane Block
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Cairo University
Low Back Pain
Safety and Efficacy Study of an Etoricoxib and Tizanidine Fixed Dose Combination in Participants With Moderate to Severe Acute Low Back Pain (MK-0663B-164)
The primary objective of this study is to evaluate the safety and tolerability of MK-0663B (etoricoxib/tizanidine) among participants with moderate-to-severe acute low back pain.
- Trial name
- NCT01979510
- Testing
- MK-0663B, DOLOCAM PLUS®, Acetaminophen 500 mg
- Sponsor
- Merck Sharp & Dohme LLC