Clinical trials: Acute Back Pain
Low Back Pain
The Prognostic Value of Biomarkers and the Effect of Tolperisone in Acute Low Back Pain and Sciatic Pain "BETA"
The main purpose of the trial is to identify biomarkers from the blood as well as electrophysiologic and morphometric features (chemical, electrophysiologic and ultrasound biomarkers) that reflect the intensity of pain and/or…
- Trial name
- BETA (NCT05544656)
- Testing
- Tolperisone Hydrochloride
- Where
- Hungary
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Semmelweis University
Erector Spinae Plane Block, Serratus Posterior Superior Intercostal Plane Block
Comparison of Erector Spinae Plane Block and Serratus Posterior Superior Intercostal Plane Block
Breast cancer is the most common malignancy in women. Modified radical mastectomy, a surgical procedure in the treatment of breast cancer, is one of the standard treatments.
- Conditions
- Erector Spinae Plane Block, Serratus Posterior Superior Intercostal Plane Block, Acute Pain, Postoperative Pain
- Trial name
- NCT06407037
- Testing
- Erector Spinae Plane Block, Serratus Posterior Superior Intercostal Plane Block
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Diskapi Yildirim Beyazit Education and Research Hospital
Acute Muscle Pain
Evaluation of Efficacy and Safety of SPARC1401 in Acute Low Back Pain
A phase 2 randomized clinical trial to evaluate efficacy and safety of SPARC1401 at three dose levels in patients with acute low back pain
- Trial name
- NCT02887534
- Testing
- SPARC1401-low dose, SPARC1401-mid dose, SPARC1401-high dose
- Sponsor
- Sun Pharma Advanced Research Company Limited
Acute Low Back Pain
Nonivamide/Nicoboxil Ointment in Acute Low Back Pain
The aim of this study is to assess the efficacy and tolerability of Nicoboxil/Nonivamide ointment in comparison to Nicoboxil, Nonivamide, and placebo ointments for the treatment of acute low back pain.
- Trial name
- NCT01708915
- Testing
- nicoboxil, nonivamide + nicoboxil (Finalgon), nonivamide
- Where
- 37 sites in Germany
- Volunteers
- 805 people
- Sponsor
- Boehringer Ingelheim
Acute Low Back Pain
A Randomized Study of Three Medication Regimens for Acute Low Back Pain
Low back pain causes 2.4% of visits to US emergency departments (ED) resulting in 2.7 million visits annually. In a general low back pain (LBP) population, prognosis is poor.
- Trial name
- NCT01587274
- Testing
- Naproxen, Cyclobenzaprine, Oxycodone/ acetaminophen
- Where
- United States
- Volunteers
- 323 people
- Sponsor
- Montefiore Medical Center
Sciatica, Sciatica Due to Intervertebral Disc Disorder
Transforaminal Epidural Injection in Acute Sciatica
Patients suffering from sciatica are treated conservatively for the first 8 weeks due to the favourable prognosis. This period is preferably extended up to 14-16 weeks after which patients may opt for surgery.
- Conditions
- Sciatica, Sciatica Due to Intervertebral Disc Disorder, Sciatic Radiculopathy
- Trial name
- TEIAS (NCT03924791)
- Testing
- Lidocaine, Methylprednisolone Acetate, Dexamethasone
- Where
- 2 sites in Netherlands
- Volunteers
- 142 people
- Sponsor
- C.L.A.Vleggeert-Lankamp
Acupuncture, Low Back Pain
Accessible Acupuncture for the Warrior With Acute Low Back Pain
The objective of this study is to determine if auricular acupuncture and/or the acupuncture point governor vessel 26 (GV26) with manual tonification is superior to conservative management (NSAIDs) at reducing acute low back pain…
- Trial name
- NCT04236908
- Testing
- NSAIDS, Battlefield Acupuncture, GV26 with manual tonification
- Where
- United States
- Volunteers
- 276 people
- Sponsor
- David Moss
Postoperative Acute Pain, Breast Cancer
IPP-PSP Block vs. SPSIPB in Breast Surgery
This prospective, randomized clinical study aims to compare the analgesic efficacy of the interpectoral-pectoserratus plane block and the serratus posterior superior intercostal plane block for postoperative pain management in…
- Conditions
- Postoperative Acute Pain, Breast Cancer, Regional Anesthesia
- Trial name
- NCT07246720
- Testing
- Interpectoral-Pectoserratus Plane Block, Serratus Posterior Superior Intercostal Plane Block
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Zonguldak Bulent Ecevit University
Acute Low Back Pain
Efficacy and Safety of NVP-1203 in Patients With Acute Low Back Pain
The purpose of this study is to evaluate the efficacy and safety NVP-1203 in patients with Acute low back pain
- Trial name
- NCT03341832
- Testing
- NVP-1203, NVP-1203-R
- Where
- South Korea
- Volunteers
- 91 people
- Sponsor
- NVP Healthcare
Low Back Pain
Interest of the Return to Primary Care of the "Low Back Pain Booklet" of Health Insurance in the Recovery of Common Acute Low Back Pain
Low back pain is defined as pain or functional discomfort between the twelfth rib and the gluteal fold, which may be median or lateralised. It can radiate up to the thigh but never below the knee.
- Trial name
- NCT03953625
- Testing
- delivery of the low back pain booklet
- Where
- France
- Volunteers
- 33 people
- Sponsor
- Fondation Hôpital Saint-Joseph
Back Pain, Muscle Pain
Transcutaneous Electrical Nerve Stimulation for Back Pain in the Emergency Department (TENS-ED)
The effectiveness of Transcutaneous Electrical Nerve Stimulation (TENS) to reduce pain scores for patients with acute back pain in an ambulatory emergency department (ED) population will be examined in this dual-center, cluster…
- Conditions
- Back Pain, Muscle Pain, Acute Pain, Lower Back Pain
- Trial name
- TENS-ED (NCT05601843)
- Testing
- Transcutaneous Electrical Nerve Stimulation (TENS)
- Where
- Canada
- Volunteers
- 25 people
- Sponsor
- Sam Brophy
Pain, Acute, Muscle Soreness
Analgesic Induces Similar Upper and Lower Body Pain Pressure Threshold Increases
Background: Both health professionals and consumers use menthol-based topical analgesics extensively for the temporary relief of pain from musculoskeletal ailments or injury.
- Conditions
- Pain, Acute, Muscle Soreness, Tendon Injuries
- Trial name
- NCT04677985
- Testing
- Menthol based topical analgesic
- Where
- Canada
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Memorial University of Newfoundland
Low Back Pain, Mechanical
Battlefield Acupuncture for Acute/Subacute Back Pain in the Emergency Department
The randomized controlled study aims was to investigate the pain control of Battle Field Acupuncture as Primary or Adjunctive Treatment in Back Pain (Acute Musculoskeletal pain) in the (acute pain setting) Emergency Department vs…
- Trial name
- NCT03996564
- Testing
- Battlefield Acupuncture, Acetaminophen, Diclofenac
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- San Antonio Military Medical Center
Acute Low Back Pain, Musculoskeletal Pain
Physiotherapy in Emergency Department for Acute Lumbar Spasm
This retrospective observational study aims to evaluate the effectiveness of physiotherapy interventions-such as manual therapy, electrotherapy (TENS), and individualized exercise programs-in managing acute lumbar spasm in…
- Conditions
- Acute Low Back Pain, Musculoskeletal Pain, Emergency Care
- Trial name
- PT-ED (NCT06987656)
- Testing
- Standard Pharmacologic Treatment, Physiotherapy Intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people
- Sponsor
- Duzce University
Back Pain, Acute Pain
Gonyautoxin 2/3 in the Treatment of Acute Back Pain: A Clinical Proof-of-concept Study
This was an interventional, double-blind, placebo controlled, randomized, single dose, proof-of-concept study. It was a single-center clinical trial.
- Trial name
- NCT04799041
- Testing
- GTX 2/3
- Where
- Chile
- Volunteers
- 30 people
- Sponsor
- Algenis SpA
Arthroplasty, Replacement, Knee, Anesthesia, Conduction
Adductor Canal Vs Adductor Canal Plus SPANK Block for Postoperative Pain in Knee Arthroplasty Surgery
This study will prospectively investigate the efficacy of Adductor canal block with periarticular infiltration Vs Adductor canal block, Periarticluar infiltration and Sensory posterior articular nerve of the knee block in…
- Conditions
- Arthroplasty, Replacement, Knee, Anesthesia, Conduction, Acute Pain
- Trial name
- NCT04290442
- Testing
- adductor canal block, SPANK, Ropivacaine
- Where
- United States
- Sponsor
- Bruce Ben-David
Postoperative Pain, Acute, Shoulder Pain
Ultrasound-Guided Serratus Posterior Superior Intercostal Plane Block for Analgesia in Arthroscopic Shoulder Surgery
This study aimed to evaluate the effectiveness of serratus posterior superior intercostal plane (SPSIP) block in managing postoperative pain in patients undergoing arthroscopic shoulder surgery.
- Conditions
- Postoperative Pain, Acute, Shoulder Pain, Serratus Posterior Superior Intercostal Plane Block
- Trial name
- SPSIP (NCT07394673)
- Testing
- Group SPSIP: Serratus Posterior Superior İntercostal Plane Block (SPSIP)
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Bursa City Hospital
Acute Pain, Low Back Pain
Tactile Acuity in Experimentally Induced Acute Low Back Pain
The purpose of this study is to determine whether experimentally induced acute low back pain might lead to alteration in lumbar tactile acuity measured in region affected by pain compared to pain-free side and pain-free controls.
- Trial name
- NCT03021278
- Testing
- Saline injection
- Where
- Poland
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- The Jerzy Kukuczka Academy of Physical Education in Katowice
Preventive Medicine
Preventing Chronicity of Sub-acute Low Back Pain by Altering the Neural Emotional Response to Pain
Aim of the study It could be stated that chronification of low back pain in some respects depends on the emotional reactions to the acute pain state.
- Trial name
- NCT05450263
- Testing
- Interoceptive exposure
- Where
- Finland
- Sponsor
- Orton Orthopaedic Hospital
Sub-acute Back Pain
Effect of L-dopa In Subacute Back Pain Population
This study aims to determine if early treatment with Carbidopa/Levodopa and Naproxen in individuals with sub-acute back pain (SBP) is associated with changes in blocking transition to chronic back pain (CBP).
- Trial name
- NCT01951105
- Testing
- Naproxen, Carbidopa/Levodopa
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- Northwestern University