Clinical trials: Acute Back Pain
Low Back Pain
Efficacy of Metamizole Versus Ibuprofen and a Short Educational Intervention Versus Standard Care in Acute Low Back Pain
The EMISI trial is a randomized, double blind, controlled trial (RCT) using a factorial design in patients with a new low back pain episode.
- Trial name
- EMISI (NCT04111315)
- Testing
- Metamizole Sodium, Ibuprofen 600 mg, Patient education
- Where
- Switzerland
- Volunteers
- 120 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Moderate to Severe Acute Lower Back Pain
Safety and Efficacy of SP-103 in Subjects With Moderate to Severe Acute Lower Back Pain
This is a Phase 2, randomized, double-blind, placebo-controlled, parallel group, multicenter study to evaluate the safety and efficacy of SP-103 in subjects with moderate to severe acute lower back pain.
- Trial name
- NCT05096494
- Testing
- SP-103
- Where
- 10 sites in United States
- Volunteers
- 76 people
- Sponsor
- Scilex Pharmaceuticals, Inc.
Acupuncture, Acute Low Back Pain
The Evaluation of Single Acupoint Therapy to Acute Low Back Pain
Low back pain is the leading course of disability , affecting patients' health and work. Recently, studies have reveal the fact that patients get insufficient physical activity and easily let acute stage turn to chronic type.
- Trial name
- NCT04328428
- Testing
- acupuncture
- Where
- Taiwan
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Low Back Pain
Evaluation of a Program to Prevent Recurrences of Episodes of Acute Low Back Pain, Assisted by the Axomove Application
The purpose of this study is to demonstrate that the prescription of specific exercises, supervised by a numerical application, reduces the rate of recurrence of episodes of acute low back pain
- Trial name
- NA-PLU-MALODOS (NCT07915128)
- Testing
- 2 exercises program supervised by a physical therapist via a digital application, Care as usual
- Volunteers
- 194 people
- Sponsor
- University Hospital, Bordeaux
Acute Postoperative Pain, Chest Wall Surgery
Prospective Feasibility, Analgesic Effectiveness, and Safety Study of a Visual Analog Scale-Guided Multimodal Pain Algorithm After Posterior Rib Remodeling With Osteosynthesis
This prospective single-group study will evaluate a visual analog scale-guided multimodal analgesia algorithm during the first five days after posterior rib remodeling with osteosynthesis.
- Trial name
- NCT07805928
- Testing
- VAS-Guided Multimodal Analgesia Algorithm, Ultrasound-Guided Thoracic Wall Regional Block
- Where
- Colombia
- Volunteers
- 160 people
- Sponsor
- Research Inc
Back Pain, Chronic Pain
Haloperidol for Pain Control in Patients With Acute Musculoskeletal Back Pain in the Emergency Department
Single center, double-blind, randomized, controlled trial in patients who present to the emergency department (ED) with a chief complaint of back pain.
- Trial name
- NCT06395428
- Testing
- Haloperidol, Ketorolac Tromethamine
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Western Michigan University School of Medicine
Funnel Chest, Excavatum, Pectus
Cryoanalgesia to Prevent Acute and Chronic Pain Following Nuss Procedure
This Study study compared standard therapy (multimodal and regional analgesia) versus a novel approach (Cryoanalgesia combined with bilateral erector spine plane block and multimodal analgesia) in subjects undergoing minimal…
- Trial name
- NCT05570097
- Testing
- intercostal nerves cryoanalgesia
- Where
- Poland
- Volunteers
- 40 people
- Sponsor
- Pomeranian Medical University Szczecin
Thoracic Anesthesia, Postoperative Pain
Serratus Posterior Superior Intercostal Plane Block Versus Intrathecal Morphine in VATS
This study aims to compare the analgesic effects of the serratus posterior superior intercostal plane block and intrathecal morphine in patients undergoing video-assisted thoracoscopic surgery.
- Conditions
- Thoracic Anesthesia, Postoperative Pain, Video Assisted Thoracic Surgery (VATS)
- Trial name
- NCT07540104
- Testing
- Intrathecal Morphine, Serratus Posterior Superior Intercostal Plane Block
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Ondokuz Mayıs University
Acute Low Back Pain
Efficacy and Safety of Dexketoprofen/Vitamin B Vs Dexketoprofen for Post-traumatic Cervical Sprain Grade I-II
Phase IIIb, multicenter, prospective, randomized, double-blind study to evaluate the fixed combination of Desketoprofen / Vitamin B in the management of acute pain in patients with cervical sprain grade I-II of the Quebec scale.
- Trial name
- WHIPLASH (NCT05001555)
- Testing
- Dexketoprofen/Vitamin B, Dexketoprofen
- Where
- Mexico
- Volunteers
- 174 people, healthy volunteers welcome
- Sponsor
- Laboratorios Silanes S.A. de C.V.
Herpes Zoster
Esketamine Combined With PRF of DRG for Acute/Subacute Zoster-associated Pain
To assess the 1-month effects and safety of esketamine - PRF -standardized drug treatment against PRF -standardized drug treatment acute/subacute zoster-associated pain (ZAP) patients.
- Trial name
- NCT06914206
- Testing
- esketamine group, PRF group
- Where
- China
- Volunteers
- 184 people
- Sponsor
- Beijing Tiantan Hospital
Pain, Postoperative, Pain, Acute
SPSIPB for Breast Cancer Surgery
Acute postoperative pain after breast cancer surgery is usually moderate to severe, and inadequate postoperative pain management can significantly increase perioperative analgesic consumption, prolong hospital stay, and even…
- Conditions
- Pain, Postoperative, Pain, Acute, Opioid Consumption
- Trial name
- NCT06225908
- Testing
- Serratus posterior superior intercostal plane block
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Zonguldak Bulent Ecevit University
Lumbago
Anesthetic Block of the Erector Muscles of the Lumbar Spine to Relieve Acute Lumbar Pain: Pilot Study
This study concerns the treatment of recent lumbago and aims to evaluate the efficacy of an anesthetic block of the erector spinae muscles combining ropivacaine and dexamethasone.
- Trial name
- NCT06511765
- Testing
- Ropivacaine and dexamethasone injection solution, Sodium Chloride 0.9% Injection Solution
- Where
- France
- Volunteers
- 40 people
- Sponsor
- Elsan
Low Back Pain
Muscle Energy Technique Versus Back Stretching Among Non-specific Low Back Pain-subacute
This study will highlight LBP management using MET and stretching application among subacute type of back pain
- Trial name
- NCT05360121
- Testing
- Muscle energy technique of erector spinae muscle, Muscle energy technique of quadratus lumborum muscle, Stretching of erector spinae muscle
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Dow University of Health Sciences
Subacromial Impingement Syndrome, Glenohumeral Internal Rotation Deficit
The Acute Effects of Different Stretching Methods in Individuals With Subacromial Impingement Syndrome
The purpose of this study is to investigate and compare the acute effects of isolytic and static stretching training in individuals having subacromial impingement syndrome with glenohumeral internal rotation deficit.
- Trial name
- NCT03246867
- Testing
- Isolytic stretching group, Static stretching group, Control group
- Where
- Turkey (Türkiye)
- Volunteers
- 69 people
- Sponsor
- Dokuz Eylul University
Subacute and Chronic Non-specific Low Back Pain
Comparison of the Effectiveness of 2 Manual Therapies on Functional Outcome in Sub-acute and Chronic Non-specific Low Back Pain
The purpose of this study is to determine whether a standardised osteopathic manipulative treatment is more effective than a placebo of osteopathic manipulative treatment, in sub-acute and chronic non-specific low back pain on…
- Trial name
- LC OSTEO (NCT02034864)
- Testing
- Osteopathic manipulative treatment
- Where
- France
- Volunteers
- 400 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Radiculopathy Lumbar, Disk Herniated Lumbar
Position-Induced Opening of the Intervertebral Foramen is Efficient to Treat an Acute Lumbosacral Radiculopathy Caused by Disc Herniation
Efficiency of the conservative mechanical lumbosacral nerve root decompression, as an adjunct to pharmacological treatment, in the case of acute lumbosacral radiculopathy.
- Conditions
- Radiculopathy Lumbar, Disk Herniated Lumbar, Low Back Pain
- Trial name
- NCT04276519
- Testing
- Physiotherapeutic, non-invasive position-induced opening of the intervertebral foramen
- Volunteers
- 20 people
- Sponsor
- General Hospital Sveti Duh
Neck Pain, Low Back Pain
Study to Demonstrate That Muscle Pattern Recognition (MPR) is an Effective Evaluation Tool for Musculoskeletal Neck or Back Pain
The investigators hypothesize that non able-bodied participants with reported acute, sub-acute, or chronic symptoms of neck or back pain of a musculoskeletal origin will have magnetic resonance imaging (MRI), X-ray and blood…
- Trial name
- NCT00134225
- Testing
- Muscle Pattern Recognition (MPR)
- Where
- 4 sites in United States, Canada
- Volunteers
- 480 people, healthy volunteers welcome
- Sponsor
- iTech Medical, Inc.
Back Pain, Epidural Analgesia, Obstetric
Ultrasound-Guided Landmark and Epidural Site Pain
Historically, women who have chronic back pain after pregnancy have attributed the cause to the epidural procedure. While many studies have shown no greater incidence of generalized post-partum back pain in those who received an…
- Trial name
- NCT02813681
- Testing
- US-epidural SVD, Spontaneous vaginal delivery without an Epidural
- Volunteers
- 80 people
- Sponsor
- The University of Texas Medical Branch, Galveston
Acute and Chronic Non-radicular LBP
Topical Lidocaine Patch in Low Back Pain
Patients with acute or chronic Lower Back Pain (LBP) participated in a Phase IV clinical trial to assess the effectiveness of Lidoderm administered once daily (q24h) for 2 weeks in the treatment of acute and chronic LBP.
- Trial name
- NCT00904540
- Testing
- Lidoderm®
- Where
- 7 sites in United States
- Volunteers
- 131 people
- Sponsor
- Endo USA Inc., a Keenova Therapeutics Company
Low Back Pain
Randomized, Double Blind, Multicenter Study of the Safety and Efficacy of Valdecoxib 40 mg Once Daily Compared With Diclofenac 75 mg Twice Daily in Acute Low Back Pain
The pain relief, safety, and tolerability of valdecoxib 40 mg once daily compared with diclofenac 75 mg twice daily for acute low back pain was studied.
- Trial name
- NCT00649610
- Testing
- valdecoxib, diclofenac
- Where
- 29 sites in Argentina, Brazil and 7 more
- Volunteers
- 340 people
- Sponsor
- Pfizer