Clinical trials: Acute Cardiac Syndrome
Acute Coronary Syndrome
Assessing Force-velocity Profile: an Innovative Approach to Optimize Cardiac Rehabilitation in Coronary Patients
Cardiac rehabilitation includes aerobic and anaerobic training adapted to cardiovascular pathology for which cardiac rehabilitation is prescribed.
- Trial name
- CITIUS (NCT04102410)
- Testing
- Sprints, Vertical jumps, Questionary Short Form-12 (SF-12)
- Where
- France
- Volunteers
- 120 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Stable Angina, Unstable Angina
Low Rate Fluoroscopy to Reduce Radiation Dose During Coronary Angiography and Intervention
Objectives: To determine the efficacy of low rate fluoroscopy at 7.5 frames per second (FPS) vs. conventional 15 FPS for reduction of operator and patient radiation dose during diagnostic coronary angiography and percutaneous…
- Conditions
- Stable Angina, Unstable Angina, Acute Coronary Syndrome
- Trial name
- NCT01990924
- Testing
- 15 FPS, 7.5 FPS
- Where
- Canada
- Volunteers
- 385 people
- Sponsor
- Laval University
Heart Diseases, Heart Valve Diseases
Acute Kidney Injury After Cardiac Surgery
The study aims to identify the Following: - 1. incidence and mortality of cardiac Surgery associated -AKI based on the new consensus diagnostic systems of KDIGO (Kidney Disease Improving Global Outcomes). 2.
- Conditions
- Heart Diseases, Heart Valve Diseases, Heart Shock, Cardiac Disease
- Trial name
- NCT05079724
- Testing
- Cardiac Surgery
- Volunteers
- 200 people
- Sponsor
- Assiut University
Acute Coronary Syndrome, Plaque, Atherosclerotic
Prediction of Vulnerable Plaque Using Coronary CT Angiography and Computational Fluid Dynamic in Acute Coronary Syndrome
The aim of the PVCFD trial is to predict vulnerable plaque confirmed by OCT using coronary CT angiography and computational fluid dynamics in patients with acute coronary syndrome.
- Trial name
- PVCFD (NCT04524117)
- Volunteers
- 200 people
- Sponsor
- Shanghai 10th People's Hospital
Myocardial Infarction, Acute Coronary Syndrome
Impact at One Year of a Secondary Prevention Educational Program on Cardiovascular Risk Factors
In secondary prevention, the beneficial role of cardiac rehabilitation programs after myocardial infarction, percutaneous coronary intervention or coronary artery bypass is now well established.
- Trial name
- OLIMPIC (NCT00758810)
- Where
- 4 sites in France
- Volunteers
- 354 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Acute Coronary Syndrome, Tobacco Use
Post Acute Cardiac Event Smoking (PACES) Study
Summary of the Project : Quitting smoking following acute coronary syndrome (ACS) can reduce mortality up to 50%. However, depression and smoking are highly co-morbid and depressed mood may interfere with cessation and…
- Trial name
- NCT03413423
- Testing
- BAT-CS, Smoking Cessation and Health & Wellness
- Where
- United States
- Volunteers
- 233 people
- Sponsor
- Hennepin Healthcare Research Institute
Acute Coronary Syndromes, Stable Angina Pectoris
Angio-Seal® vs. Exo-Seal® for Closure of Arterial Puncture Sites
Background: Vascular closure devices (VCD) were developed to reduce access site bleedings, to improve patients´ comfort, and to accelerate ambulation after percutaneous coronary interventions (PCI).
- Trial name
- NCT01669382
- Testing
- percutaneous coronary intervention
- Where
- 3 sites in Germany
- Volunteers
- 304 people
- Sponsor
- University Hospital Erlangen
Acute Coronary Syndrome, Diabetes Mellitus, Type 2
Simvastatin and Fenofibrate vs Simvastatin Alone in Patients With Type 2 Diabetes Mellitus and Acute Coronary Syndrome
To test the hypothesis that early (within 5-21 days after index event) administration of combined lipid-lowering therapy in extremely high risk population of patients with type 2 diabetes mellitus (T2DM) and hypertriglyceridemia…
- Conditions
- Acute Coronary Syndrome, Diabetes Mellitus, Type 2, Hypertriglyceridemia
- Trial name
- NCT02015988
- Testing
- Fenofibrate, Simvastatin
- Where
- Ukraine
- Volunteers
- 60 people
- Sponsor
- Koval' O., MD
Myocardial Ischemia, Hypertension
ARCHIPELAGO: Irbesartan in Patients With Acute Coronary Syndrome Without ST Segment Elevation
Primary Objective The main objective of this study is to assess if a two-month regimen of irbesartan in patients hospitalized for acute coronary syndrome without ST segment elevation can reduce inflammation markers (ie hsCRP), in…
- Trial name
- NCT00296218
- Testing
- Irbesartan
- Where
- 11 sites in United States, Belgium and 9 more
- Volunteers
- 440 people
- Sponsor
- Sanofi
Acute Kidney Injury, Heart Failure
Remote Ischemic Preconditioning for Renal and Cardiac Protection in Congestive Heart Failure (RICH) Trial
This is a prospective, double-blind, sham-controlled, multicenter, randomized clinical trial is to study the effects of remote ischemic preconditioning on contrast-associated acute kidney injury, functional capacity, and major…
- Conditions
- Acute Kidney Injury, Heart Failure, Contrast Induced Nephropathy, Coronary Angiography
- Trial name
- RICH (NCT04982419)
- Testing
- Remote ischemic preconditioning
- Where
- 3 sites in United States
- Volunteers
- 240 people
- Sponsor
- VA Office of Research and Development
Coronary Artery Disease, Chest Syndrome
CT Stress Myocardial Perfusion, Fractional Flow Reserve and Angiography in Patients With Stable Chest Pain Syndromes
The purpose of the DYNAMITE trial (Dynamic CT stress myocardial perfusion, CT fractional flow reserve (FFR-CT) and coronary CT angiography for optimized treatment strategy in patients with chest pain syndromes) is to determine…
- Conditions
- Coronary Artery Disease, Chest Syndrome, Acute Myocardial Infarction, Heart Failure
- Trial name
- DYNAMITE (NCT04709900)
- Testing
- CT angiography, FFR-CT and stress CT myocardial perfusion
- Where
- Denmark
- Volunteers
- 2,000 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Acute Coronary Syndrome, Cognitive Impairment
Effect of CI on Prognosis in the Elderly Patients With ACS
This study aims to investigate the incidence and characteristics of cognitive Impairment(CI) in the elderly patients with acute coronary syndrome (ACS), and to determine whether CI are predictive of the prognosis of major adverse…
- Conditions
- Acute Coronary Syndrome, Cognitive Impairment, Elderly
- Trial name
- CIACS (NCT04278911)
- Testing
- MMSE and MoCA
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Beijing Friendship Hospital
Acute Coronary Syndrome, Chest Pain
Comparison of Accelerated Diagnostic Pathways for Acute Chest Pain in Emergency Departments in the United Arab Emirates
This is a prospective four-site cohort study, which will accrue adults with symptoms concerning for acute coronary syndrome over a period of 12 months.
- Trial name
- NCT05532787
- Testing
- Application of acute chest pain risk stratification scores (HEART and EDACS)
- Where
- 5 sites in United Arab Emirates
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- Zayed Military Hospital
Bleeding ,Arrhythmias, Heart Failure, Acute Renal Failure, Acute Liver Failure, Dyspnoea, Gout
Extended Drug Utilization Study Among Patients Exposed to Ticagrelor, Clopidogrel and Prasugrel
The purpose of the study is to describe patient characteristics and drug usage among patients that are prescribed ticagrelor for the first time and to compare them with patients who are prescribed clopidogrel and prasugrel for…
- Trial name
- NCT01276275
- Testing
- Risk of selected safety events
- Where
- Sweden
- Volunteers
- 7,200 people
- Sponsor
- AstraZeneca
Acute Coronary Syndromes, Coronary Artery Disease
Computed Tomographic Coronary Angiography for Acute Chest Pain Evaluation
The purpose of this study is to evaluate whether 64-slice Computed Tomographic coronary angiography is useful for rapid diagnosis or exclusion of significant coronary artery disease in patients who present to the Emergency…
- Trial name
- EDCCTA (NCT00615719)
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- Virginia Commonwealth University
Atheroma; Heart
Assessment of GARP Expression in Acute and Chronic Coronary Syndrome
The leading cause of death is cardiovascular diseases in occidental countries. Of those, atherosclerosis is the major contributor to this burden being notably responsible for strokes and myocardial infarctions.
- Trial name
- GARP-CS (NCT07384910)
- Testing
- Arterial blood sample
- Where
- Belgium
- Volunteers
- 600 people
- Sponsor
- Université Catholique de Louvain
Cardiogenic Shock, Postresuscitation Disease
Role of Candidate Proteins in Capillary Leakage During Acute Circulatory Failure
Testing the association between circulating candidate proteins and the level of vascular leakage for three distinct forms of circulatory failure: cardiogenic shock, septic shock, and post-resuscitation syndrome.
- Conditions
- Cardiogenic Shock, Postresuscitation Disease, Septic Shock
- Trial name
- NCT05586282
- Where
- France
- Volunteers
- 380 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Acute Coronary Syndrome
The Effect on EPCs by Statin Loading in "All Comers" With an ACS
Cardiovascular disease is a major cause of morbidity and mortality worldwide. There are a number of risk factors for coronary artery disease and all to often patients admitted with an acute coronary syndrome have these…
- Trial name
- ALL COMERS (NCT02957162)
- Testing
- Atorvastatin, Blood samples
- Where
- United Kingdom
- Volunteers
- 40 people
- Sponsor
- University Hospitals of North Midlands NHS Trust
Acute Coronary Syndrome, Unstable Angina
Acute Coronary Syndrome Sri Lanka Audit Project
ACSSLAP is the first island wide audit project in Sri Lanka on ACS.
- Conditions
- Acute Coronary Syndrome, Unstable Angina, Non ST Elevation Myocardial Infarction, ST Elevation Myocardial Infarction
- Trial name
- ACSSLAP (NCT02893280)
- Testing
- aspirin, clopidogrel, statin, enoxaparin, streptokinase
- Where
- Sri Lanka
- Sponsor
- University of Colombo
Atherosclerosis, Stroke
Vascular Inflammation Imaging Using Somatostatin Receptor Positron Emission Tomography
This VISION study aims to investigate the role of inflammation in atherosclerosis using 68Ga- DOTATATE PET, and to validate 68Ga-DOTATATE PET imaging for the detection and quantification of vascular inflammation in the aorta…
- Conditions
- Atherosclerosis, Stroke, Transient Ischemic Attack, Chronic Stable Angina
- Trial name
- VISION (NCT02021188)
- Where
- United Kingdom
- Volunteers
- 42 people
- Sponsor
- University of Cambridge
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