Clinical trials: Acute Cardiac Syndrome
Cardiac Rehabilitation, Heart Failure
Cardiac REhabilitation COhort at the Medicine Campus DaVos to invEstigate Recovery
The RECOVER study, titled Cardiac Rehabilitation Cohort at the Medicine Campus Davos for Exploration of Recovery, is a prospective, non-interventional, monocentric cohort study conducted at the Hochgebirgsklinik Davos.
- Conditions
- Cardiac Rehabilitation, Heart Failure, Cardiac Arrest (CA), ACS (Acute Coronary Syndrome)
- Trial name
- RECOVER (NCT07096973)
- Where
- Switzerland
- Volunteers
- 10,000 people
- Sponsor
- Hochgebirgsklinik Davos
Coronary Artery Disease, Chest Pain
The Value of CT-FFR Compared to CCTA or CCTA and Stress MPI in Low to Intermediate Risk ED Patients With Toshiba CT-FFR
Coronary Computed Tomography Angiogram (CCTA) is a non-invasive imaging modality that has high sensitivity and negative predictive value for the detection of coronary artery disease (CAD).
- Conditions
- Coronary Artery Disease, Chest Pain, Acute Coronary Syndrome, Acute Myocardial Infarction
- Trial name
- NCT03329469
- Testing
- Toshiba CT-FFR
- Where
- United States
- Volunteers
- 1,142 people
- Sponsor
- Northwell Health
Acute Coronary Syndrome, Chronic Coronary Syndrome
Common Femoral Vein-to-Artery Diameter Ratio for Detection of Elevated LVEDP
This prospective cross-sectional diagnostic accuracy study enrolled patients undergoing coronary angiography and left heart catheterization at Burapha University Hospital, Thailand.
- Conditions
- Acute Coronary Syndrome, Chronic Coronary Syndrome, Heart Failure
- Trial name
- NCT07866859
- Testing
- Ultrasound Measurement of Common Femoral Vein-to-Artery Diameter Ratio
- Where
- Thailand
- Volunteers
- 105 people
- Sponsor
- Burapha University
Cardiac Ischemia, Acute Coronary Syndrome
Instantaneous Wave-free Ratio Guidance Strategy Evaluation in the Treatment of Multivessel Acute Coronary Syndrome.
A single-center, prospective, randomized, open-label, blinded end-point clinical trial of instantaneous wave-free ratio (iFR) guidance strategy impact on clinical outcomes in multivessel acute coronary syndrome (ACS) patients.
- Trial name
- iStrategy (NCT05006183)
- Testing
- PCI
- Where
- Latvia
- Volunteers
- 150 people
- Sponsor
- Daugavpils Regional Hospital
Acute Coronary Syndrome
Preventive Intervention Value of DCB in Vulnerable Coronary Atherosclerotic Plaques
The PASSIVATE-CAP study is an investigator-initiated, prospective, randomized, multicenter, open-label superiority trial focusing on acute coronary syndrome (ACS) patients with nonflow-limiting vulnerable plaques in nonculprit…
- Trial name
- NCT06416813
- Testing
- GDMT+DCB
- Where
- China
- Volunteers
- 140 people
- Sponsor
- Yong He
Atherosclerosis, Stroke, Ischemic
Adherence to Secondary Prevention Guidelines for Cardiovascular Risk
The present observational study aims to determine the degree of adherence to the recommendations of clinical guidelines regarding the prevention of cardiovascular complications in patients hospitalized due to a cardiovascular…
- Conditions
- Atherosclerosis, Stroke, Ischemic, Acute Coronary Syndrome, Ischemic Heart Disease
- Trial name
- NCT06450561
- Testing
- cardiovascular event
- Where
- Spain
- Volunteers
- 129 people
- Sponsor
- Consorci Sanitari de l'Alt Penedès i Garraf
Coronary Artery Disease, Percutaneous Coronary Intervention
Effect and Efficacy of Xpedition™/Alpine™, Everolimus-eluting Stent for Coronary Atherosclerosis
The objectives of this study are 1. To establish a prospective registry of the whole patients who received percutaneous coronary intervention with Xience Xpedition™/Alpine™ stent 2.
- Conditions
- Coronary Artery Disease, Percutaneous Coronary Intervention, Acute Coronary Syndrome, Angina Pectoris
- Trial name
- HOST-ALPINE (NCT02845804)
- Testing
- Alpine
- Where
- 20 sites in South Korea
- Volunteers
- 1,533 people
- Sponsor
- Seoul National University Hospital
Coronary Heart Disease
SB-480848 in Major Adverse Cardiovascular Events - Integrated Summary of Efficacy and Safety From the STABILITY Trial (LPL100601) and the SOLID-TIMI-52 Trial (SB-480848/033)
The overall objective of this integrated analysis is to evaluate the clinical safety and efficacy of long-term treatment with darapladib enteric coated tablets, 160mg, as compared to placebo when added to standard of care in…
- Trial name
- NCT01636271
- Testing
- darapladib
- Volunteers
- 28,855 people
- Sponsor
- GlaxoSmithKline
Chest Pain
"SVEAT" Chest Pain Scoring System
This is a prospective, observational study to assess the efficacy of the newly developed SVEAT scoring system in identifying low-risk patients who may be eligible for early discharge.
- Trial name
- NCT03511430
- Where
- United States
- Volunteers
- 370 people
- Sponsor
- University of Nevada, Reno
Acute Coronary Syndrome
Suxiao Jiuxin Pills in Microvascular Obstruction in Patients With Acute Coronary Syndrome
Microvascular obstruction is the severe complication of percutaneous coronary intervention (PCI) in patients with acute coronary syndrome. Microvascular obstruction after PCI is often association with poor prognosis.
- Trial name
- NCT04814121
- Testing
- Suxiao Jiuxin Pills
- Volunteers
- 198 people
- Sponsor
- Guangzhou University of Traditional Chinese Medicine
Acute Coronary Syndromes
LUNAR IIIb Study Comparing Rosuvastatin and Atorvastatin in Subjects With Acute Coronary Syndromes
Comparison of rosuvastatin and atorvastatin in subjects with acute coronary syndromes
- Trial name
- NCT00214630
- Testing
- rosuvastatin calcium, atorvastatin
- Where
- 56 sites in United States, Costa Rica and 3 more
- Volunteers
- 825 people
- Sponsor
- AstraZeneca
Coronary Artery Disease, Chronic Coronary Syndrome
Artificial Intelligence-Driven Medipixel Fractional Flow Reserve Versus Invasive Fractional Flow Reserve-Guided PCI Trial (AIM-FFR Trial)
The AIM-FFR trial is a prospective, multi-center, open-label, randomized controlled, non-inferiority trial. The current trial will evaluate non-inferiority of MPFFR-guided PCI, compared with invasive FFR-guided PCI in patients…
- Conditions
- Coronary Artery Disease, Chronic Coronary Syndrome, Acute Coronary Syndrome
- Trial name
- AIM-FFR (NCT07329699)
- Testing
- MPFFR or Invasive FFR
- Where
- 23 sites in South Korea
- Volunteers
- 2,100 people
- Sponsor
- Samsung Medical Center
Acute Coronary Syndrome
Atorvastatin Versus Rosuvastatin on Contrast Induced Acute Kidney Injury (PRATO-ACS 2)
The aim of the project is to compare the nephro-protective effects of high-dose atorvastatin and high-dose rosuvastatin on the incidence of Contrast Induced-Acute Kidney Injury in patients with non-ST-elevation acute coronary…
- Trial name
- PRATO-ACS-2 (NCT01870804)
- Testing
- Rosuvastatin, Atorvastatin
- Where
- Italy
- Volunteers
- 760 people
- Sponsor
- Centro Cardiopatici Toscani
Acute Coronary Syndrome, Percutaneous Coronary Intervention
Registry of Bleeding Risk in Real World Chinese Acute Coronary Syndrome Patients-II
The present study was designed to observe the incidence of bleeding events and characteristics of bleeding and exploratively analyse bleeding related biomarkers and gene polymorphisms in ACS patients undergoing PCI.
- Conditions
- Acute Coronary Syndrome, Percutaneous Coronary Intervention, Bleeding
- Trial name
- NCT03402711
- Where
- China
- Volunteers
- 5,500 people
- Sponsor
- Chinese PLA General Hospital
Acute Coronary Syndrome
Ticagrelor in Fuwai Hospital
This is a single-arm non-interventional cohort study. This study is to describe the contemporary use of ticagrelor in a "real-world" setting, to reflect its acceptance and patients' compliance, and to observe its one-year safety…
- Trial name
- TIFU (NCT02765711)
- Where
- China
- Volunteers
- 1,200 people
- Sponsor
- Chinese Academy of Medical Sciences, Fuwai Hospital
Cardiovascular Diseases, Acute Coronary Syndrome
Enhancing Rural Health Via Cardiovascular Telehealth for Rural Patients Implementation (E-VICTORS)
This pre-post study will evaluate the implementation of a cardiovascular telehealth platform, which will connect experts from the Wake Forest University Health Sciences (WFUHS) tertiary care center with Wilkes County Emergency…
- Trial name
- E-VICTORS (NCT04617834)
- Testing
- Quality Surveillance Data Collection
- Where
- 4 sites in United States
- Volunteers
- 215 people
- Sponsor
- Wake Forest University Health Sciences
Acute Coronary Syndrome
EVOlocumab for Early Reduction of LDL-cholesterol Levels in Patients With Acute Coronary Syndromes (EVOPACS)
Reduction of low-density lipoprotein cholesterol (LDL-C) levels effectively reduces the risk of adverse events in patients with established atherosclerotic cardiovascular disease.
- Trial name
- EVOPACS (NCT03287609)
- Testing
- Evolocumab 140 mg/mL
- Where
- 7 sites in Switzerland
- Volunteers
- 308 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Acute Coronary Syndromes
RADIATION PROTECTion With a Pelvic Lead Shield and a Radiation Protection Cap for Operators Performing Coronary Angiography or Intervention
RADIATION PROTECT is a randomized, controlled trial of patients undergoing coronary angiography or PCI with or without a pelvic lead shield.
- Trial name
- NCT02128035
- Testing
- With Lead Shield
- Where
- Canada
- Volunteers
- 230 people
- Sponsor
- Dr. Sanjit S. Jolly
Acute Coronary Syndromes
Impact of Clopidogrel Dose Adjustment According to Platelet Reactivity Monitoring in Patients With High on Treatment Platelet Reactivity Undergoing Percutaneous Coronary Intervention
Acute coronary syndromes are related to the development of a platelet derived thrombus on a ruptured coronary atheroma. Use of dual antiplatelet therapy aspirin-thienopyridine a significantly reduced the risk of major adverse…
- Trial name
- NCT01505790
- Testing
- PRASUGREL, Clopidogrel
- Where
- France
- Volunteers
- 187 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
Acute Coronary Syndromes (ACS), Ventricular Tachycardia (VT)
Analysis of Life-threatening ARrhythMias After Acute Coronary Syndrome
Patients admitted with an acute coronary syndrome (ACS) are at increased risk of malignant cardiac arrhythmias (MA), such as sustained ventricular tachycardia and ventricular fibrillation.
- Conditions
- Acute Coronary Syndromes (ACS), Ventricular Tachycardia (VT), Ventricular Fibrillation, Pulseless Electrical Activity
- Trial name
- ALARM-ACS (NCT07824050)
- Where
- Netherlands
- Volunteers
- 2,775 people
- Sponsor
- Catharina Ziekenhuis Eindhoven
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