Clinical trials: Acute Care Medical
PROM, PREM
Trends of Patient-reported Outcome Measures (PROMs) in Multimorbid Medical Patients Hospitalized for an Acute Illness
currently, PROMs and PREMs are not routinely collected and compared among medical inpatients of Swiss university hospitals, nor is a standard set of PROMs and PREMs available for use in Swiss hospitals.
- Conditions
- PROM, PREM, Quality of Care, Internal Medicine
- Trial name
- TRADUCE (NCT06597318)
- Testing
- Hospitalization
- Where
- Switzerland
- Volunteers
- 1,000 people
- Sponsor
- University of Lausanne Hospitals
Emergencies, Cardiopulmonary Arrest
Simulation Trial of Telemedical Support for Paramedics
In the United States, the current standard of prehospital (i.e. outside of hospitals) emergency care for children with life-threatening illnesses in the community includes remote physician support for paramedics providing…
- Conditions
- Emergencies, Cardiopulmonary Arrest, Acute Respiratory Failure, Status Epilepticus
- Trial name
- R01 (NCT06441760)
- Testing
- Video teleconsultation, Audio support
- Where
- 9 sites in United States
- Volunteers
- 420 people
- Sponsor
- Boston Medical Center
Acute Myeloid Leukemia, Neutropenia
Home Away From Home - Medical Outcomes
Treatment for pediatric acute myeloid leukemia (AML) involves intensive chemotherapy regimens that result in periods of profound neutropenia leaving patients susceptible to severe infectious complications.
- Conditions
- Acute Myeloid Leukemia, Neutropenia, Bacteremia
- Trial name
- Aim 1 (NCT02774850)
- Where
- 17 sites in United States
- Volunteers
- 610 people
- Sponsor
- Children's Hospital of Philadelphia
Type 2 Diabetes Mellitus
Telemedicine Strategy With Home Treatment Save Resources
Progress in technology has made telemedicine-based solutions with video consultations available in the management and treatment of chronic diseases like diabetes, heart failure and lung insufficiency at home.
- Trial name
- NCT02214017
- Testing
- A videotelephone, TandBerg E20,, Behavioral motivation
- Where
- Denmark
- Volunteers
- 40 people
- Sponsor
- Kolding Sygehus
Abdomen, Acute
Geographic Influences on Emergency Laparotomy Outcomes
Introduction 'Emergency Laparotomy' is an umbrella term for a set of commonly performed procedures which are known to carry a significant risk of mortality and morbidity.
- Trial name
- NCT02017977
- Where
- United Kingdom
- Volunteers
- 40,000 people
- Sponsor
- University of Edinburgh
Stroke
Decentralized Imaging by REmote Computer Tomography for Cerebral Infarct Thrombolysis
The DIRECT-CT trial is designed to test the hypothesis that remote controlled CT scanning combined with real time audio-and video conference (AVC) guided assessment from an experienced hospital stroke team (tele-stroke) at…
- Trial name
- DIRECT-CT (NCT07530588)
- Testing
- Decentralized diagnostics and treatment
- Where
- 2 sites in Norway
- Volunteers
- 52 people
- Sponsor
- University Hospital of North Norway
Aortic Valve Stenosis, Cardiac Conduction Disturbance
Remote Cardiovascular Monitoring in Post-TAVI Patients
The goal of this randomised clinical trial is to utilise a remote monitoring algorithm to gather essential clinical data, aiming to guide the management of post-Transcatheter Aortic Valve Implantation (TAVI) patients and reduce…
- Conditions
- Aortic Valve Stenosis, Cardiac Conduction Disturbance, Digital Health, Transcatheter Aortic Valve Implantation
- Trial name
- TELE-TAVI (NCT06602609)
- Testing
- Remote Patient Monitoring Strategy, Standard Medical Therapy
- Where
- United Kingdom
- Volunteers
- 216 people
- Sponsor
- Imperial College London
Acute Illness, Acute Injury
Videoconferencing Between Ambulances and Physician at the Emergency Medical Dispatch Center, Effects on On-Site Patient Treatment and Patterns of Referral
The prehospital resources are limited. The emergency medical dispatch center (EMDC) is manned by qualified health care personnel around the clock.
- Trial name
- NCT02095067
- Testing
- Video consultation
- Where
- 2 sites in Denmark
- Volunteers
- 150 people
- Sponsor
- University of Aarhus
Myocardial Infarction (MI), Acute Coronary Syndromes (ACS)
Prehospital Point-of-Care Hs-Troponin I for Rule-Out of Acute Myocardial Infarction in Patients Without ST-Segment Elevation
People who call emergency medical services (EMS) with chest pain or other possible heart-related symptoms are often taken to hospital for further testing.
- Trial name
- Pre-POCT TnI (NCT07563998)
- Testing
- Prehospital high-sensitivity cardiac troponin I measurement
- Where
- Denmark
- Volunteers
- 500 people
- Sponsor
- Central Denmark Region
Orthostatic Hypotension
State of Knowledge Among Nurses Regarding the Screening for Orthostatic Hypotension in Elderly Individuals in Acute Geriatric Medicine and Medical and Rehabilitation Services
Orthostatic hypotension is a common geriatric syndrome associated with an increased risk of falls, syncope, functional decline and mortality in older adults.
- Trial name
- HTO-IDE (NCT07738666)
- Testing
- Administration of questionnaires on nurses' knowledge of orthostatic hypotension, its measurement, diagnosis and management
- Where
- France
- Volunteers
- 30 people
- Sponsor
- Hôpital NOVO
Pulmonary Edema, Acute Lung Injury
Fluid Management in the Post-Anesthetic Care Unit (PACU) at Sourasky Medical Center
Peri-operative fluid therapy is a controversial area with few randomized trials to guide practice. Fluid management has a significant influence on outcome following surgery.
- Conditions
- Pulmonary Edema, Acute Lung Injury, Hypertension, Renal Failure
- Trial name
- NCT00995228
- Where
- Israel
- Volunteers
- 1,000 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
Cerebrovascular Accident
Field Administration of Stroke Therapy - Magnesium (FAST-MAG) Trial
The goal of this study is to evaluate the effectiveness and safety of field-initiated magnesium sulfate in improving the long-term functional outcome of patients with acute stroke.
- Trial name
- FAST-MAG (NCT00059332)
- Testing
- Magnesium Sulfate, Normal Saline
- Where
- United States
- Volunteers
- 1,700 people
- Sponsor
- Jeffrey L. Saver
Respiratory Infections
Improving Antibiotic Use in Acute Care Treatment
Purpose The emergence and rapid rise in antibiotic resistance among common bacteria are adversely affecting the clinical course and health care costs of community-acquired infections.
- Trial name
- IMPAACT (NCT00144040)
- Testing
- Physician & patient education on appropriate antibiotic use, Rapid C-reactive protein testing to guide antibiotic treatment
- Where
- 9 sites in United States
- Volunteers
- 1,000 people
- Sponsor
- US Department of Veterans Affairs
Dementia, Confusion
Trial of a Medical and Mental Health Unit for Older People
This research is an evaluation of the MMHU compared to standard care. Patients who are over 65 and 'confused' at admission will be randomly allocated to the MMHU or standard care.
- Conditions
- Dementia, Confusion, Cognitive Impairment, Delirium
- Trial name
- TEAM (NCT01136148)
- Testing
- A medical and mental health unit
- Where
- United Kingdom
- Volunteers
- 600 people
- Sponsor
- University of Nottingham
Pulmonary Embolism, Pulmonary Embolism Without Mention of Acute Cor Pulmonale
NT-proBNP as a Tool for the Detection of Acute Pulmonary Artery Embolism (APE)
In patients with suspected APE (Acute Pulmonary Embolism) referred to the intensive care unit (ICU)after major surgery, serum NT-proBNP (N-terminal proBNP), Troponin-I and D-dimers were measured according to the standard hospital…
- Trial name
- NCT01633671
- Where
- Germany
- Volunteers
- 44 people
- Sponsor
- University of Ulm
Geriatric Disorder
The Effect of Systematic Assessment of Functional Ability, Development of Rehabilitation Plan and Follow-up at Home for Elderly Medical Patients
The aim of this study is to examine the effect of systematic assessment of functional ability, development of rehabilitation plan and follow-up at home for elderly medical patient's risk of readmission.
- Trial name
- NCT01949831
- Testing
- Assessment of functional ability in combination with follow-up at home
- Where
- Denmark
- Volunteers
- 52 people
- Sponsor
- Aarhus University Hospital
Adherence, Medication
Use of a Smartphone Application to Increase Adherence to Medical Treatment in Patients With an Acute Coronary Syndrome.
ADHERENCE is a randomized unicentric study that will be carried out from a monovalent center of cardiology of the Autonomous City of Buenos Aires.
- Trial name
- ADHERENCE (NCT03766789)
- Testing
- Cell phone application
- Where
- Argentina
- Volunteers
- 90 people
- Sponsor
- Instituto Cardiovascular de Buenos Aires
Emergencies
Time Within the Acute Care Chain: How Long Have Medical Emergency Department Patients Spent
This study is part of a research domain focusing on the acute care chain, which includes the patient journey from symptoms to treatment on the Emergency Medical Department (ED).
- Trial name
- TACC (NCT06079099)
- Where
- 6 sites in Netherlands
- Volunteers
- 583 people
- Sponsor
- Maastricht University Medical Center
Advanced Medical Illness
Integrating Palliative Care Social Workers Into Sub-Acute Settings: A Feasibility Trial
This is a feasibility trial utilizing a step wedge design of a social worker led palliative care intervention for 120 adult patients with advanced medical illness being cared for in a subacute nursing facility.
- Trial name
- ALIGN (NCT03546920)
- Testing
- ALIGN Intervention Phase
- Where
- United States
- Volunteers
- 220 people
- Sponsor
- University of Colorado, Denver
Musculoskeletal Injury, Fracture
A Skills-Based Program Delivered Via Secure Live Video to Patients With Acute Musculoskeletal Trauma
The aims of this study are to test a manualized mind body skills-building program aimed at preventing the development of chronic pain and disability following acute musculoskeletal injury in at-risk patients.
- Trial name
- NCT03405610
- Testing
- The Toolkit for Optimal Recovery after Injury
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- Massachusetts General Hospital