Clinical trials: Acute Cerebrovascular Accident
Healthy
Stroke Volume at Rest and During Exercise in Healthy Volunteers
Background Changes in cardiac output, driven by increased heart rate and stroke volume, are crucial for oxygen delivery during acute exercise and influence maximal oxygen uptake (VO₂max).
- Trial name
- NCT07318844
- Testing
- Cardiopulmonary exercise test
- Where
- Denmark
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Acute Ischemic Stroke
Safety of NRICM301 Added to Standard Care in Adults With Acute Ischemic Stroke
This study will examine the short-term safety and tolerability of NRICM301, a food-grade herbal formula also known as Taiwan Xingnao No. 1, when added to standard care for adults hospitalized with acute ischemic stroke.
- Trial name
- NCT07902934
- Testing
- NRICM301
- Volunteers
- 45 people
- Sponsor
- Tri-Service General Hospital (TSGH)
Acute Ischemic Stroke, Tenecteplase
Intravenous Tenecteplase in Very Old Patients With Acute Ischemic Stroke
The benefit of intravenous tenecteplase in very old patients with acute ischemic stroke (AIS) remain uncertain. This real-world study aims to evaluate the effectiveness and safety of intravenous tenecteplase in AIS patients aged…
- Trial name
- NCT07475936
- Testing
- Tenecteplase (TNK) (0.25 mg/kg, to maximum of 25mg), Standard medical care
- Where
- China
- Volunteers
- 392 people
- Sponsor
- First Affiliated Hospital of Guangxi Medical University
Acute Ischemic Stroke
Intra-arterial Selective Hypothermic Magnesium Sulfate Infusion in Combination With Endovascular Thrombectomy in Acute Ischemic Stroke
The primary objective of this study is to estimate the safety and effectiveness of selective intra-arterial hypothermic magnesium sulfate infusion after endovascular thrombectomy in patients with acute ischemic stroke.
- Trial name
- ICE-MAG (NCT07163299)
- Testing
- Endovascular thrombectomy combination with selective intra-arterial hypothermic magnesium sulfate infusion (350 ml)., Endovascular thrombectomy combination with selective intra-arterial hypothermic magnesium sulfate infusion (500 ml)., Endovascular thrombectomy combination with selective intra-arterial hypothermic magnesium sulfate infusion (650 ml).
- Where
- China
- Volunteers
- 42 people
- Sponsor
- Capital Medical University
Acute Ischemic Stroke
Biomarkers to Predict Hemorrhage and Outcomes After Endovascular Treatment in Patients With Acute Large Vessel Occlusion
The main aim of the biomarkers to predict Hemorrhagic transformation(HT) after endovascular treatment in Acute Ischemic Stroke Patients. The study has three main parts.
- Trial name
- NCT03915834
- Testing
- Endovascular treatment
- Where
- 2 sites in China
- Volunteers
- 300 people
- Sponsor
- Capital Medical University
Acute Stroke
NF-L Chain Measurement in Acute Ischemic Stroke
1. Using neurofilament light chain as a diagnostic tool and predictor of outcome of acute ischemic stroke 2. Using neurofilament light chain in detecting severity in old ischemic stroke
- Trial name
- NCT06090058
- Testing
- Measurement of neurofilament light chain
- Volunteers
- 150 people
- Sponsor
- Assiut University
Severe Stroke, Acute Stroke
Controlling Hypertension After Severe Cerebrovascular Event
The purpose of this academic lead study is to explore ideal blood pressure targets and optimum individualized anti-hypertension strategies in acute severe stroke.
- Conditions
- Severe Stroke, Acute Stroke, Hypertension
- Trial name
- CHASE (NCT02982655)
- Testing
- Individualized BP lowering
- Where
- 26 sites in China
- Volunteers
- 500 people
- Sponsor
- Xijing Hospital
Aspiration, Acute Ischemic Stroke
Safety and Efficacy of Intracranial Thrombus Aspiration Catheter in the Treatment of Acute Large-vessel Occlusive Stroke
A prospective, multicenter, single-arm objective performance criteria trial to investigate the safety and efficacy of SINOMED ADPAT for Recanalization Therapy in acute large-vessel occlusive stroke.
- Conditions
- Aspiration, Acute Ischemic Stroke, Large-vessel Occlusion
- Trial name
- NCT05101668
- Testing
- Intracranial Thrombosis Aspiration Catheter
- Where
- 6 sites in China
- Volunteers
- 26 people
- Sponsor
- Sinomed Neurovita Technology Inc.
Ischemic Stroke
ReStore Thrombectomy Trial for Flow Restoration in Acute Ischemic Stroke Patients
The ReStore™ Thrombectomy device restores blood flow in the neurovascular by removing thrombus in patients experiencing ischemic stroke.
- Trial name
- NCT01437774
- Testing
- thrombectomy (ReStore or Merci)
- Where
- 4 sites in United States
- Volunteers
- 210 people
- Sponsor
- Reverse Medical Corporation
Cerebrovascular Stroke
Sub-Acute Stroke Rehabilitation With AMES
The AMES device is designed to produce functional cortical changes by:(1) assisting the subject as he/she attempts to move the limb (assisted movement) and (2) enhancing movement sensation by vibrating the muscles during movement…
- Trial name
- AMES (NCT00609115)
- Testing
- AMES device (test), AMES device (crossover)
- Where
- 5 sites in United States
- Volunteers
- 83 people
- Sponsor
- AMES Technology
Stroke Acute
PERSonalized rObotic NeurorehAbilitation for Stroke Survivors
The aim is to carry out a first clinical study, to expand existing knowledge about the neurophysiological mechanisms underlying post-stroke recovery.
- Trial name
- PERSONA (NCT06312540)
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- Azienda Ospedaliero, Universitaria Pisana
Dysphagia, Stroke
NMES Plus Conventional Therapy for Stroke Dysphagia
Aim: The aim of this study is to investigate the effect of neuromuscular electrical stimulation (NMES) combined with traditional dysphagia therapy (TDT) in acute/subacute stroke patients with dysphagia.
- Trial name
- NCT07415785
- Testing
- neuromuscular electrical stimulation, traditional dysphagia therapy
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- Chiayi Christian Hospital
Endovascular Therapy, Acute Ischaemic Stroke
Stratified Blood Pressure Management After Endovascular Treatment for Acute Ischemic Stroke
The RESCUE-BP is a multi-centered, prospective, randomized, open label, blinded endpoint (PROBE) phase III trial. In patients with acute ischemic stroke who have undergone endovascular treatment and achieved successful…
- Conditions
- Endovascular Therapy, Acute Ischaemic Stroke, Collateral Circulation, Blood Pressure Management
- Trial name
- RESCUE-BP (NCT07527013)
- Testing
- Stratified Blood Pressure Management
- Where
- China
- Volunteers
- 544 people
- Sponsor
- Beijing Tiantan Hospital
Acute Stroke, Cerebral Ischemia
PMZ-1620 (Sovateltide) in Acute Ischemic Stroke Patients
This was a prospective, multicentric, randomized, double blind, parallel, saline controlled Phase II clinical study to compare the safety and efficacy of PMZ-1620 (INN: Sovateltide) therapy along with standard supportive care in…
- Trial name
- NCT04046484
- Testing
- Normal Saline along with standard treatment, PMZ-1620 along with standard treatment
- Where
- 7 sites in India
- Volunteers
- 40 people
- Sponsor
- Pharmazz, Inc.
Stroke, Ischemic, Thrombectomy
Prognostic Value of Isolated and Combined Score Aspects in Acute Ischemic Stroke
This study, called TARGET-ASPECT, looks at patients who had a type of stroke called acute ischemic stroke and were treated with clot-busting medicine and a procedure to remove the clot.
- Conditions
- Stroke, Ischemic, Thrombectomy, Thrombolytic Therapy, Brain Ischemia
- Trial name
- NCT07069452
- Where
- France
- Volunteers
- 152 people
- Sponsor
- Centre Hospitalier de Gonesse
Stroke, Ischemic Stroke
Optimizing Patient's Selection for Endovascular Treatment in Acute Ischemic Stroke
SELECT is a multicenter, observational prospective study implementing a protocol to acquire imaging and clinical variables known to affect clinical outcomes after endovascular therapy in an effort to evaluate and compare the…
- Trial name
- SELECT (NCT02446587)
- Testing
- Mechanical Thrombectomy
- Where
- 9 sites in United States
- Volunteers
- 500 people
- Sponsor
- The University of Texas Health Science Center, Houston
Acute Stroke, Anxiety Disorders
Anxiety and Depression Disorder in Patient Treated With rTPA for Mangment of Acute Ischemic Stroke
In fact theWorld Health Organization estimates that 2-3% in general populations of countries across the world tend to be affected by severe mental disorders (1) Thrombolytic therapy seems to be of great importance in achieving…
- Conditions
- Acute Stroke, Anxiety Disorders, Depression
- Trial name
- NCT04484558
- Testing
- Actilyse
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Assiut University
Sarcopenia, Cerebral Stroke
Prevalence of Sarcopenia in Stroke Patients
The goal of this observational study is to analyze the characteristics of sarcopenia-related variables in post-acute and chronic stroke patients using various clinical measurement tools.
- Conditions
- Sarcopenia, Cerebral Stroke, Cerebral Vascular Accident (CVA)/Stroke
- Trial name
- NCT07492849
- Testing
- Objective assessments, Subjective assessment
- Where
- Taiwan
- Volunteers
- 80 people
- Sponsor
- Cishan Hospital, Ministry of Health and Welfare
Acute Stroke
APERIO® HYBRID Thrombectomy Device for Flow Restoration in Vessels of Patients Experiencing Acute Ischemic Stroke
This is a prospective, multicenter, single-arm, open-label, national Post-Market Clinical Follow-up study to collect comprehensive information on technical and clinical success and safety of the use of APERIO® Hybrid(17/21)…
- Trial name
- NCT04457479
- Where
- Germany
- Volunteers
- 190 people
- Sponsor
- Acandis GmbH
Acute Stroke
Neutrophil Extracellular Traps and Thrombolysis in the Acute Stroke
The purpose of the study was to investigate the correlation between the nucleosome concentration and the rate of recanalization after thrombolysis.
- Trial name
- NETs (NCT02476188)
- Testing
- Sample of Blood
- Where
- France
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier St Anne
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.