Clinical trials: Acute Chest Pain
Postoperative Pain, Chest Pain
Transversus Thoracis Muscle Plane Block for Postoperative Pain in Adult Cardiac Surgery
Inadequate pain control after coronary artery bypass graft surgery increases mortality and results in a higher incidence of persistent poststernotomy pain syndrome.
- Conditions
- Postoperative Pain, Chest Pain, Coronary Artery Bypass, Sternotomy
- Trial name
- NCT04591119
- Testing
- Transversus Thoracic Muscle Plane Block, Parasternal Intercostal Plane Block
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people
- Sponsor
- Muğla Sıtkı Koçman University
Chest Pain, Coronary Artery Disease
ARgentinean Risk Assessment Registry in ACS; the ARRA-RACS Study
The first aim of this trial is to assess the long-term prognostic value of Omega-3 index, which is a measure of eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) relative to other fatty acids in the erythrocyte membrane…
- Conditions
- Chest Pain, Coronary Artery Disease, Unstable Angina Pectoris, Myocardial Infarction
- Trial name
- ARRA-RACS (NCT01377402)
- Where
- 10 sites in Argentina, Norway
- Volunteers
- 982 people
- Sponsor
- Helse Stavanger HF
Non-ST Elevation Myocardial Infarction, Acute Coronary Syndrome
One-hour Troponin in a Low-prevalence Population of Acute Coronary Syndrome
This study aims to evaluate if the 1-hour rule-in/rule-out algorithm for a high-sensitivity cardiac troponin T (hs-cTnT) is safe and effective for use in the primary care where the patients have a lower pretest probability of an…
- Conditions
- Non-ST Elevation Myocardial Infarction, Acute Coronary Syndrome, Angina, Unstable, NSTEMI - Non-ST Segment Elevation MI
- Trial name
- OUT-ACS (NCT02983123)
- Testing
- 1-hour hs-cTnT
- Where
- Norway
- Volunteers
- 1,750 people
- Sponsor
- Oslo University Hospital
Acute Coronary Syndrome, Myocardial Infarction
Rule Out Myocardial Infarction by Computer Assisted Tomography
The goal of this research is to determine noninvasively whether detection of coronary stenosis and plaque by multidetector computed tomography (MDCT) in patients with acute chest pain suspected of acute coronary syndrome (ACS)…
- Conditions
- Acute Coronary Syndrome, Myocardial Infarction, Unstable Angina Pectoris
- Trial name
- ROMICAT (NCT00990262)
- Testing
- Cardiac Computed Tomography
- Where
- United States
- Volunteers
- 368 people
- Sponsor
- Massachusetts General Hospital
Perioperative Complications, Perioperative/Postoperative Complications
Perioperative Database of Chinese Elderly Patients
The investigators aim to establish a prospective database of perioperative elderly patients from multiple regions and centers. Collected data involves postoperative complications of the central nervous system, cardiovascular…
- Conditions
- Perioperative Complications, Perioperative/Postoperative Complications, Perioperative Adverse Events
- Trial name
- PDCEP (NCT04911530)
- Testing
- no intervention
- Where
- China
- Volunteers
- 10,000 people
- Sponsor
- Chinese PLA General Hospital
Unstable Angina or Non ST Elevated Myocardial Infarction
Downstream Versus Upstream Strategy for the Administration of P2Y12 Receptor Blockers
To evaluate the impact on outcomes of the currently accepted antithrombotic strategies based on the administration of newer P2Y12 receptor blockers (prasugrel and ticagrelor) in a population of non ST elevated ACS (NSTEACS)…
- Trial name
- DUBIUS (NCT02618837)
- Testing
- Downstream strategy, Upstream strategy
- Where
- Italy
- Volunteers
- 2,520 people
- Sponsor
- University of Padova
Myocardial Infarction (MI), Chest Pain Rule Out Myocardial Infarction
The Rule-Out Acute Myocardial Infarction Using Aritifical Intelligence Electrocardiogram (ROMIAE) 2 Trial
This study is to see whether the AI ECG assisted protocol is as safe and efficacious as conventional protocol in early triage of suspected myocardial infarction.
- Trial name
- ROMIAE 2 (NCT07027891)
- Testing
- AI-ECG
- Where
- 12 sites in South Korea
- Volunteers
- 4,670 people
- Sponsor
- CHA University
Post Operative Pain, Pain, Acute
Post-thoracotomy Pain Management With Active External Warming and Ice Application
The aim of study is to investigate the effects of active external warming of patient concurrently with application of ice to incision site on thoracotomy pain and analgesic consumption.
- Conditions
- Post Operative Pain, Pain, Acute, Thoracic Injury
- Trial name
- NCT05299788
- Testing
- Active external warming, Ice application
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Akdeniz University
Myocardial Ischemia
Metabolic Efficiency With Ranolazine for Less Ischemia in Non-ST Elevation Acute Coronary Syndromes
MERLIN-TIMI 36 is a multi-national, double-blind, randomized, placebo-controlled, parallel-group clinical trial designed to evaluate the efficacy and safety of ranolazine during acute and long-term treatment in approximately…
- Trial name
- NCT00099788
- Testing
- Ranolazine
- Where
- United States
- Volunteers
- 6,560 people
- Sponsor
- Gilead Sciences
Myocardial Infarction or Chest Pain
ROMIAE (Rule-Out Acute Myocardial Infarction Using Artificial Intelligence Electrocardiogram Analysis) Trial
This study is a prospective multicenter observational study for external validation and model advancement of a deep learning based 12-lead electrocardiogram analysis algorithm targeting adult patients presenting to the emergency…
- Trial name
- ROMIAE (NCT05435391)
- Where
- South Korea
- Volunteers
- 8,814 people
- Sponsor
- CHA University
Solid Carcinoma, 5-Fluorouracil Toxicity
Prevention of Chest Pain in Chemo-treated Cancer Patients
This is a prospective, exploratory, randomised clinical trial. Patients with diagnosed cancer that are to be treated with 5-fluorouracil (5-FU) will be randomised into standard oncological treatment or a cardiological assessment…
- Conditions
- Solid Carcinoma, 5-Fluorouracil Toxicity, Cardiotoxicity, Chemotherapeutic Toxicity
- Trial name
- CATCH (NCT03486340)
- Testing
- Cardiologic assessment
- Where
- Denmark
- Volunteers
- 218 people
- Sponsor
- Vejle Hospital
Thoracic Anesthesia, Nerve Block
The Effects of Three Different Ultrasound-guided Nerve Blocks in VATS
Ultrasound-guided mid-point transverse process to pleura block, erector spinae plane block and paravertebral block are three different methods of nerve block, used for relieving postoperative pain in thoracic anesthesia.
- Conditions
- Thoracic Anesthesia, Nerve Block, Pain, Acute
- Trial name
- NCT04829409
- Testing
- Paravertebral block, ESP block, MTP block
- Where
- China
- Volunteers
- 90 people
- Sponsor
- Huazhong University of Science and Technology
Acute Coronary Syndrome, Acute Myocardial Infarction
Coronary Computed Tomographic Angiography in Emergency Department Chest Pain Patients at Intermediate Risk of Acute Coronary Syndrome
The purpose of this study is to determine whether Coronary Computed Tomographic Angiography (CCTA) will increase patient safety by decreasing the rate of missed ACS and adverse events in patients who receive standard care plus…
- Conditions
- Acute Coronary Syndrome, Acute Myocardial Infarction, Unstable Angina, Coronary Disease
- Trial name
- CCTA (NCT00473863)
- Testing
- Coronary Computed Tomographic Angiography
- Where
- Canada
- Volunteers
- 150 people
- Sponsor
- Vancouver General Hospital
Pain Management, Thoracic Trauma
Comprehensive Multicenter Study on the Management of Acute Pain Following Thoracic Combat-Related Trauma in Ukraine
This study is a multicenter clinical trial conducted in Vinnytsia, Rivne, and Lviv, Ukraine, focusing on the management of acute pain following thoracic injuries sustained during combat.
- Conditions
- Pain Management, Thoracic Trauma, Pulmonary Function, Quality of Life
- Trial name
- CMS-APT-UA (NCT07380789)
- Testing
- Cryoablation, Radiofrequency ablation alone
- Where
- Ukraine
- Volunteers
- 50 people
- Sponsor
- Lviv National Medical University
Acute Coronary Syndrome, NSTEMI - Non-ST Segment Elevation MI
Safety of Accelerated Rule-out Protocols in Patients Admitted With Chest Pain to a Crowded Chest Pain Unit (CPU)
The aim of this observational study registry is to assess the safety of a Non-ST-elevation myocardial infarction (STEMI) rapid rule-out strategy as proposed by European Guidelines in patients presenting with suspected acute…
- Trial name
- NCT03111862
- Testing
- NSTEMI Rule-Out according to hs-TnT
- Where
- Germany
- Volunteers
- 3,567 people
- Sponsor
- University Hospital Heidelberg
Acute Myocardial Infarction, Cardiovascular Morbidity
Dapagliflozin Effects on Mayor Adverse Cardiovascular Events in Patients With Acute Myocardial Infarction (DAPA-AMI)
The actual evidence is solid about the use of de SGLT2-inhibitors in wide spectrum of cardiorenal targets, which has been shown in a great amount of randomized clinical trials compared with placebo.
- Conditions
- Acute Myocardial Infarction, Cardiovascular Morbidity, Heart Failure, Angina, Unstable
- Trial name
- DAPA-AMI (NCT04717986)
- Testing
- Dapagliflozin 10Mg Tab
- Where
- Mexico
- Volunteers
- 188 people
- Sponsor
- Instituto Mexicano del Seguro Social
Acute Coronary Syndromes
A Post Marketing Surveillance to Evaluate the Safety and Efficacy of Brilinta
To identify the following items through the post marketing surveillance under routine clinical practice after marketing authorization of Brilinta Tablet: the occurrence of unrevealed Serious Adverse Events (SAEs), current status…
- Trial name
- NCT01611272
- Where
- 23 sites in South Korea
- Volunteers
- 3,402 people
- Sponsor
- AstraZeneca
Chest Pain, Acute Aortic Dissection
Prospective Multicenter Study for Early Evaluation of Acute Chest Pain
In this study, clinical database and blood sample bank of acute chest pain (ACP) will be established at chest pain center of multi-center hospital.
- Conditions
- Chest Pain, Acute Aortic Dissection, Pulmonary Embolism, Acute Myocardial Infarction Type 1
- Trial name
- PEACP (NCT04122573)
- Testing
- Coronary angiography, CT angiography of aorta, CT angiography of pulmonary arteries.
- Where
- 9 sites in China
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- West China Hospital
Chest Pain
Copeptin and Acute Coronary Syndrome Without ST-segment Elevation
The purpose of this study is to determine whether the combination of copeptine and troponin adds diagnosis information to that provided by troponin alone or the combination of troponin and myoglobin.
- Trial name
- NCT01334645
- Testing
- Copeptin
- Where
- France
- Volunteers
- 134 people
- Sponsor
- University Hospital, Clermont-Ferrand
Acute Coronary Syndrome, Unstable Angina Pectoris
The International Survey of Acute Coronary Syndromes-ARCHIVES
ISACS ARCHIVES network is part of ISACS TC (NCT01218776) health care program. It is a collaborative network of research centers that support the rapid development of new scientific information and analytic tools.
- Conditions
- Acute Coronary Syndrome, Unstable Angina Pectoris, Myocardial Infarction, Coronary Disease
- Trial name
- ISACS-ARCHIVES (NCT04008173)
- Testing
- Non-interventional patient registry
- Where
- Italy
- Volunteers
- 130,000 people
- Sponsor
- University of Bologna