Clinical trials: Acute Cholecystitis
Cholecystitis, Acute
Benefits of Glycopyrrolate on Intubation With Rigid-videostylet (OptiScope®)
This study is intended to evaluate the efficacy and safety of glycopyrrolate as an antisialagogue prior to intubation with the rigid-videostylet(Optiscope®) in the general anesthesia settings.
- Trial name
- NCT03050242
- Testing
- Glycopyrrolate
- Where
- South Korea
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Eunah Cho, MD
Acute Cholecystitis
Is it Safe to do Laparoscopic Cholecystectomy for Acute Cholecystitis up to Seven Days?
Objectives: To compare the safety of early (≤72h) versus late (>72h-7days) laparoscopic cholecystectomy (LC) from symptom onset for acute cholecystitis (AC).
- Trial name
- RCT (NCT03999645)
- Testing
- Early laparoscopic cholecystectomy, Late laparoscopic cholecystectomy
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Damanhour Teaching Hospital
Acute Cholecystitis
Early Versus Delayed Cholecystectomy
This study examines complications, mortality rates, cost-effectiveness and safety of early laparoscopic cholecystectomy (ELC) versus delayed laparoscopic cholecystectomy (DLC).
- Trial name
- NCT03122054
- Testing
- laparoscopic cholecystectomy
- Volunteers
- 176 people
- Sponsor
- Sisli Hamidiye Etfal Training and Research Hospital
Cholecystitis, Acute, Acute Cholangitis
Visualization of the Extrahepatic biliaRy Tree Trial
This study is a prospective randomized controlled trial evaluating the use of a fluorescent dye, indocyanine green (ICG), in the identification of important bile duct anatomy during emergent same-admission cholecystectomy.
- Conditions
- Cholecystitis, Acute, Acute Cholangitis, Gallstone Pancreatitis, Choledocholithiasis
- Trial name
- VERT (NCT04922528)
- Testing
- Laparoscopic Cholecystectomy with Fluorescent Cholangiography, Laparoscopic Cholecystectomy with White Light Imaging
- Where
- Canada
- Volunteers
- 340 people
- Sponsor
- University of British Columbia
Acute Cholecystitis, Chronic Cholecystitis
Evaluation of Closed-loop TIVA Propofol, Sufentanil and Ketamine Guided by BIS Monitor
The purpose of this study is to compare a closed-loop intravenous anesthetic using Bispectral Index as a feedback loop and a controller based on reinforcement learning to titrate dose and intravenous anesthetic that is manually…
- Trial name
- NCT01942356
- Testing
- TIVA - Hypotension, TIVA - Hypertension, TIVA - Bradycardia
- Where
- United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center at San Antonio
Coronary Artery Disease, Congestive Heart Failure
Prognostic Indicators as Provided by the EPIC ClearView
The objective of this study is to determine whether the finger tip images captured by the EPIC ClearView device, when analyzed via the ClearView software, produce a Response Scale that characterizes trends consistent with known…
- Conditions
- Coronary Artery Disease, Congestive Heart Failure, Valvular Heart Disease, Atrial Fibrillation
- Trial name
- GBMC (NCT01476995)
- Where
- United States
- Volunteers
- 353 people, healthy volunteers welcome
- Sponsor
- Epic Research & Diagnostics, Inc.
Acute Cholecystitis
EUS-guided Gallbladder Drainage Instead of Laparoscopic Cholecystectomy for Acute Cholecystitis. A Feasibility Study.
To evaluate the feasibility of performing EGBD as a treatment of acute calculous cholecystitis in patients that are indicated for laparoscopic cholecystectomy.
- Trial name
- EGDB (NCT04197908)
- Testing
- EUS-guided gallbladder drainage (EGBD)
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Chinese University of Hong Kong
Covid19, Appendicitis
Operative vs Non-Operative Management of Acute Appendicitis and Acute Cholecystitis in COVID-19 Positive Patients
This study evaluates operative and non-operative management of acute appendicitis (infection or inflammation of the appendix) and acute cholecystitis (inflammation/infection of the gallbladder) in patients with active mild to…
- Conditions
- Covid19, Appendicitis, Cholecystitis, Acute, Cholecystitis; Gallstone
- Trial name
- NCT04748120
- Testing
- Operative management, Non-operative management
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- The Cleveland Clinic
Acute Cholecystitis
Validation of a New Simplified Scoring System for Acute Calculous Cholecystitis
Acute calculous cholecystitis (ACC) is the second most frequent surgical condition in emergency departments. The recommended treatment is surgical treatment (ST) and the accepted mortality is <1%, but in severe and/or fragile…
- Trial name
- ACME (NCT06213740)
- Where
- Spain
- Volunteers
- 387 people
- Sponsor
- Hospital del Mar
Acute Calculous Cholecystitis
Complications in Acute Calculous Cholecystitis
Acute calculous cholecystitis (ACC) is the second most frequent surgical condition in emergency departments, the complication rate of ACC is 8-20%, and the mortality rate is 0.5-6% in recent series.
- Trial name
- NCT05135299
- Volunteers
- 963 people
- Sponsor
- Hospital del Mar
Acute Cholecystitis
Prolonged Versus Delayed Laparoscopic Cholecystectomy for Acute Cholecystitis
Gallbladder stone affects 10-15% of the adult population, and about 15-25% of these patients presented with acute cholecystitis (AC).
- Trial name
- NCT05736003
- Testing
- Laparoscopic cholecystectomy
- Where
- Egypt
- Volunteers
- 437 people, healthy volunteers welcome
- Sponsor
- South Valley University
Cholecystitis, Acute
Effectiveness of Empirical Antibiotic Use in Mild to Moderate Acute Inflammatory Gallbladder Disease
This clinical trial is an exploratory clinical trial that evaluates the necessity and effectiveness of empirical antibiotic use in mild and moderate acute inflammatory gallbladder diseases that require surgery, and the incidence…
- Trial name
- NCT05339282
- Testing
- Laparoscopic cholecystectomy
- Where
- South Korea
- Volunteers
- 370 people
- Sponsor
- Seoul St. Mary's Hospital
Acute Cholecystitis, Postoperative Pain
Irrigation of Bupivacaine at the Surgical Bed for Postoperative Pain Relief After Laparoscopic Cholecystectomy for Acute Cholecystitis
This study aims to compare the effectiveness of irrigation of 0.5% bupivacaine versus normal saline at the gallbladder surgical bed in reducing postoperative pain following laparoscopic cholecystectomy for acute cholecystitis.
- Trial name
- NCT07851935
- Testing
- Bupivacaine 0.5%, Normal Saline 0.9%
- Where
- Pakistan
- Volunteers
- 64 people
- Sponsor
- Ziauddin University
Acute Cholecystitis, Empyema, Gallbladder
Early Laparoscopic Cholecystectomy Versus Percutaneous Cholecystostomy in Grade II Acute Cholecystitis Guidelines
The aim of this study is to compare between early laparoscopic cholecystectomy versus percutaneous cholecystostomy followed by delayed interval laparoscopic cholecystectomy as regards the operative and postoperative complications
- Trial name
- PC (NCT04979936)
- Testing
- laparoscopic cholecystectomy, percutaneous cholecystostomy
- Where
- 2 sites in Egypt
- Volunteers
- 220 people
- Sponsor
- Alexandria University
Cholecystitis, Acute, Cholecystitis
Prospective Evaluation of Ultrasound-guided Percutaneous Cholecystostomy With the Trocar Technique
The purpose of this study is to further evaluate and investigate the safety and efficacy of ultrasound (US)-guided percutaneous cholecystostomy (PC) with the trocar technique by the patient's bedside.
- Trial name
- NCT06330688
- Testing
- percutaneous cholecystostomy
- Where
- Greece
- Volunteers
- 100 people
- Sponsor
- Attikon Hospital
Acute Cholecystitis, Acute Cholecystitis With Obstruction
Patient Satisfaction After Ambulatory Emergency Laparoscopic Cholecystectomy
Acute cholecystitis is a common surgical emergency that, if left untreated, can result in significant morbidity and even death. It is characterized by inflammation of the gallbladder, usually caused by gallstones.
- Trial name
- NCT07616713
- Testing
- Laparoscopic Cholecystectomy
- Where
- Mexico
- Volunteers
- 25 people
- Sponsor
- Hospital General de Chihuahua - Dr. Salvador Zubirán Anchondo
Acute Appendicitis, Acute Cholecystitis
Web-based International Register of Emergency Surgery and Trauma
The WIRES-T project (Web-based International Registry of Emergency General Surgery and Trauma) has been set up to allow to all the EGS (Emergency General Surgery) and Trauma surgeons to register their activity and to obtain a…
- Conditions
- Acute Appendicitis, Acute Cholecystitis, Acute Diverticulitis, Post-operative Complications
- Trial name
- WIRES-T (NCT03643718)
- Testing
- Emergency General Surgery
- Where
- Italy
- Volunteers
- 10,000 people
- Sponsor
- A.O. Ospedale Papa Giovanni XXIII
Cholecystitis, Acute, Cholecystectomy, Laparoscopic
Implementation of RICA (ERAS) Guidelines in Grade II Acute Cholecystitis Undergoing Early Laparoscopic Cholecystectomy
Background Acute cholecystitis (sudden gallbladder inflammation, usually due to gallstones) is a highly frequent surgical emergency.
- Conditions
- Cholecystitis, Acute, Cholecystectomy, Laparoscopic, Enhanced Recovery After Surgery
- Trial name
- COLERICA II (NCT07695922)
- Testing
- RICA Perioperative Care Pathway
- Where
- Spain
- Volunteers
- 146 people
- Sponsor
- Hospital d'Igualada
Medical Education, Gamification
The Effectiveness of Gamification vs. Traditional Teaching in Undergraduate Medical Education
This study will evaluate the effectiveness of a gamification-based learning method (board game) versus traditional teaching (lecture) in enhancing the knowledge of acute cholecystitis and pancreatitis among medical students in…
- Trial name
- NCT06763627
- Testing
- Gamification ( Board game ), Traditional lecture-based teaching
- Where
- Iran
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Iran University of Medical Sciences
Acute Calculous Cholecystitis, Gallbladder Empyema
Role of Intra-Operative Aspiration in Distended GB in LC
Laparoscopic cholecystectomy (LC) is a standard procedure for gallstones and the standard surgical approach for acute calcular cholecystitis, superseding open cholecystectomy for gallbladder (GB) pathologies.
- Conditions
- Acute Calculous Cholecystitis, Gallbladder Empyema, Gallbladder Mucocele
- Trial name
- NCT07378410
- Testing
- Laparoscopic needle
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Aswan University