Clinical trials: Acute Conditions
Pulmonary Function
Effects of Particulate Matter on the Pulmonary Function and Acute Exacerbation of COPD and Asthma
Particulate matter(PM) exposure has been shown to increase the morbidity and mobility of a variety of respiratory diseases, including COPD and asthma.
- Trial name
- NCT03193879
- Where
- China
- Volunteers
- 505 people, healthy volunteers welcome
- Sponsor
- Peking Union Medical College Hospital
Obesity, Obesity; Endocrine
Acute and Chronic Metabolic Flexibility in Individuals Living With Obesity: The i-FLEX Study
Regular exercise is a cornerstone in the prevention and the management of cardio-metabolic risk factors. Some of the beneficial effect of exercise training occurs through metabolic flexibility' enhancement.
- Conditions
- Obesity, Obesity; Endocrine, Insulin Sensitivity, Exercise
- Trial name
- i-FLEX (NCT03527446)
- Testing
- Sprint Interval Training
- Where
- Canada
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University of New Brunswick
COVID-19, Long COVID
Using Data From a Multisensor Rapid Health Assessment Device to Predict Decompensation in Long COVID (AIDI)
We are conducting a research study at the VA hospital in Bedford, MA to learn more about how a multisensor rapid health assessment device, MouthLab, can help predict or anticipate future health complications in patients with…
- Trial name
- AIDI (NCT05713266)
- Testing
- MouthLabTM
- Where
- United States
- Volunteers
- 204 people, healthy volunteers welcome
- Sponsor
- Edith Nourse Rogers Memorial Veterans Hospital
Acute Phase Response
Disorders of the Acute Phase Response Following Trauma and Invasive Surgery
The purpose of the proposed study is to test these hypotheses through the following aims: 1. To determine if early plasmin activation following severe injury correlates with SIRS, TIC and complications throughout convalescence in…
- Trial name
- NCT03741023
- Testing
- Blood draw (venipuncture or fingerstick)
- Where
- United States
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Kinesiophobia, Pain, Acute
Adaptation of the Motor System to Experimental Pain
This study aims to measure the impact of an experimental pain on electromyography, kinematics of motion and motor cortical excitability.
- Trial name
- KinesioPoint (NCT05396820)
- Testing
- Experimental pain
- Where
- France
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Universite du Littoral Cote d'Opale
Long COVID-19 Syndrome, Long COVID Symptoms
Epigenetic Changes in Long COVID Patients
The goal of this observational study is to improve the understanding of the biological mechanisms underlying long COVID and to identify molecular biomarkers that may support its diagnosis, prognosis, and future precision medicine…
- Trial name
- ECLIPSE (NCT07757620)
- Where
- 3 sites in Italy
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Istituti Clinici Scientifici Maugeri SpA
Healthy, Females
The Combined Effect of Dairy and Exercise on Bone and Inflammation
This study analyzes whether dairy supplementation positively impacts loading exercise-induced bone cell activity and inflammation in healthy young females.
- Conditions
- Healthy, Females, Bone, Inflammation
- Trial name
- Cre-Ex-Inf (NCT03615989)
- Testing
- Resistance and Plyometric Exercise, Carbohydrate (Maltodextrin powder mixed with water), Skim Milk
- Where
- Canada
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- York University
CONTROL Condition, Exercise
Effect of Acute Exercise on Sensory and Hedonic Responses to a Fixed Meal in Adolescents With Obesity
While long considered independently, energy expenditure and energy intake have been shown to interact. Fot the last 20 years, the litterature has been describing tyhe effects of an acute bout of exercise on subsequent energy…
- Trial name
- SMASH (NCT06017440)
- Testing
- EXERCISE, CONTROL
- Where
- France
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand
Chronic Pancreatitis, Acute Recurrent Pancreatitis
Incorporating Endoscopic Ultrasound and Elastography Towards Improving Outcomes of Pediatric Pancreatitis Management
The main reason for this research study is to find out more about acute recurrent pancreatitis and chronic pancreatitis in children.
- Trial name
- NCT06068426
- Testing
- Transabdominal ultrasound Shear wave elastography
- Where
- United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- David Vitale MD
Inflammation, Endothelial Dysfunction
Effect of CEAG on Inflammation and Endothelial Function
The purpose of the study is to look at the effect a dietary supplement called CEAG [Curcuminoids, EPA (Omega-3), Astaxanthin and Gamma Linolenic Acid (GLA)] has on inflammation and endothelial (inner layer of the blood vessels)…
- Trial name
- CEAG (NCT03906825)
- Testing
- CEAG
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center
Cognitive Change, Reaction Time
Effects of A-GPC on Reaction Time and Cognitive Function
This is a randomized, double blind, crossover design study which measures the effect of alpha-glycerylphosphorylcholine (A-GPC) on reaction time and cognitive function in non-resistance trained males and females.
- Trial name
- NCT03903250
- Testing
- A-GPC, Sugar
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Mary Hardin-Baylor
Infant Behavior, Pain, Acute
Multiple Sensory Interventions On Infants' Pain and Physiological Distress During Neonatal Screening Procedures
The study purposes are to compare the effects of different combinations of sensory interventions on newborns' pain responses, physiological distress (heart rate and oxygen saturation), and crying event during heel stick…
- Conditions
- Infant Behavior, Pain, Acute, Physiological Stress, Breast Milk
- Trial name
- MSI (NCT04851353)
- Testing
- GT+VC, Smell, Taste
- Where
- Taiwan
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- National Defense Medical Center, Taiwan
COPD Exacerbation Acute, Ascaris Lumbricoides Infection
Impact of A. Lumbricoides on Pulmonary Aspergillosis Development
The prevalence of ascariasis in COPD patients with and without concomitant pulmonary aspergillosis and in controls will be determined.
- Conditions
- COPD Exacerbation Acute, Ascaris Lumbricoides Infection, Chronic Pulmonary Aspergillosis
- Trial name
- NCT05783544
- Testing
- Interleukin-1B, Interleukin-4, Interleukin-6
- Where
- Uzbekistan
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Research Institute of Epidemiology, Microbiology and Infectious Diseases, Uzbekistan
Insomnia, Healthy Adult
The Effect of Different rTMS Interventions on Acute Experimental Muscular Pain in Individuals Comorbid With Insomnia
Insomnia exacerbates pain sensitivity and impairs physiological recovery from acute musculoskeletal pain. Repetitive transcranial magnetic stimulation (rTMS) has emerged as a promising non-invasive neuromodulation intervention to…
- Conditions
- Insomnia, Healthy Adult, Exercise Induced Muscle Damage, Pain Sensitivity
- Trial name
- NCT07827677
- Testing
- Repetitive transcranial magnetic stimulation (rTMS) on L M1, Repetitive transcranial magnetic stimulation (rTMS) on R DLPFC
- Where
- Hong Kong
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Overweight, Obesity
Meta-analyses of the Effect of 'Catalytic' Doses of Fructose and Its Epimers on Carbohydrate Metabolism
Despite advances in the prevention and treatment of type 2 diabetes, its prevalence continues to rise worldwide. There is a need for new modalities to improve metabolic control in individuals with type 2 diabetes and those who…
- Conditions
- Overweight, Obesity, Dysglycemia, Prediabetes
- Trial name
- NCT02776722
- Testing
- fructose, allulose, tagatose, or sorbose
- Where
- Canada
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Stroke, Acute, Educational Problems
Off-script Diagnosis & Differential Diagnosis (D&D) Training and Residents' Stroke Knowledge
This study is a single-center, randomized, open-label, controlled, endpoint-blinded study to assess the effect of off-script diagnosis \& differential diagnosis (D\&D) training in improving the residents' knowledge of acute…
- Conditions
- Stroke, Acute, Educational Problems, Clinical Course
- Trial name
- CAST-AIS (NCT06941753)
- Testing
- Off-script diagnosis & differential diagnosis (D&D) training
- Where
- China
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Peking Union Medical College Hospital
Cirrhosis, Hepatic Encephalopathy
Brain Energy Metabolism in Patients With Chronic Liver Disease and Impaired Central Nervous System
The purpose of the current study is to look into the pathogenesis of a severe medical condition causing acute episodes on the central nervous system as seen in majority of patients with liver cirrhosis.
- Trial name
- NCT00424957
- Where
- Denmark
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Post COVID Condition, Chronic Pain
Effect of Non-Invasive Neuromodulation on Primary Chronic Pain, Including Post-COVID-19
The aim of this study is to analyse whether there is an advantage in adding low-intensity electrical stimulations to the vagus nerve with electrodes in the outer ear to control pain and fatigue in people with primary chronic…
- Conditions
- Post COVID Condition, Chronic Pain, Healthy
- Trial name
- NCT06689345
- Testing
- taVNS - transauricular vagal nerve stimulation, rPMS - repetitive peripheric magnetic stimulation, rTMS - repetitive transcranial magnetic stimulation
- Where
- Brazil
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Federal University of ABC
Acute HIV Infection, HIV Seropositive
Acute Partner and Social Contact Referral: iKnow
The primary purpose of this research is to assess the benefit of an "unaware intervention package" for identifying high risk persons who are unaware of their HIV infection status.
- Conditions
- Acute HIV Infection, HIV Seropositive, Sexually Transmitted Infections
- Trial name
- NCT02467439
- Testing
- Notification cards
- Where
- United States
- Volunteers
- 15,310 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Circadian Rhythm, Postoperative Pain
The Effect of Circadian Rhytm on Postoperative Pain Undergoing Pediatric Surgery
These circadian rhythms are self-sustained, endogenous oscillations generated by circadian clocks that persist with a period of around 24 -h under constant conditions.
- Trial name
- NCT05379192
- Testing
- Group 1, Group 2, Group 3, Group 4
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Faruk Cicekci
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