Clinical trials: Acute Conditions
Proteinuria, Kidney Injury
Inflammatory and Immune Profiling of Kidney Tissue Obtained From Patients With Newly Diagnosed Kidney Disease
This study will evaluate in patients with kidney disease, the role that certain inflammatory and immune mediators play in promoting kidney damage.
- Conditions
- Proteinuria, Kidney Injury, Chronic Kidney Disease
- Trial name
- NCT01156428
- Where
- United States
- Volunteers
- 119 people, healthy volunteers welcome
- Sponsor
- The Rogosin Institute
Covid19
Collection of SARS CoV-2 (COVID-19) Virus Secretions and Serum for Countermeasure Development
Collection of SARS-COV-2 Secretions and Serum for Countermeasure Development (aka ClinSeqSer) is an observational study to understand natural history of SARS-COV-2 infections among special populations and characterise post-covid…
- Trial name
- NCT04956445
- Where
- 2 sites in United States
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Tulane University
Acute Pain, Anxiety
Effect of Aromatherapy Massage on Pain and Anxiety After Mastectomy
This study is an interventional type three-group randomized controlled non-drug clinical trial aimed at targeting the acute pain content and anxiety level of aromatherapy arm treatment with a sesame oil and sesame lavender oil…
- Conditions
- Acute Pain, Anxiety, Mastectomy, Massage Therapy
- Trial name
- NCT05658367
- Testing
- Aromatherapy massage with sesame- lavender oil mixed, Aromatherapy massage with sesame oil, Massage with parraffin oil
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Istanbul Medipol University Hospital
Pain, Acute
Racial Discrimination, Pain, and the Buffering Influences of Acknowledgment
Black young adults (aged 18-30; N = 92) were racially included (i.e., received the ball an equal number of times) or excluded (i.e., received the ball only once) by other White players in a ball-tossing computer game called…
- Trial name
- NCT06113926
- Testing
- Bystander Acknowledgment
- Where
- United States
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- George Washington University
Acute Pain, Experimental Pain in Healthy Human Participants
Healthy Children and Virtual Reality Mediation of Simulated Pain
The objective of this study is to develop central nervous system (CNS) biomarkers of pain experienced during medical procedures and pain relief induced by Virtual Reality Pain Alleviation Therapy (VR-PAT).
- Conditions
- Acute Pain, Experimental Pain in Healthy Human Participants, Children, Adolescents
- Trial name
- NCT06854991
- Testing
- Active VR-PAT, Passive VR-PAT, iPad
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Nationwide Children's Hospital
Hyperthermia, Kidney Injury, Acute
Biomarkers to Assess Acute Kidney Injury Risk During Heat Strain
Prolonged, high intensity work in a hot environment results in significant strain on the body, known as heat strain. Heat strain in hot occupational settings such as agriculture, fire suppression, and military work can lead to…
- Trial name
- NCT05710978
- Testing
- Work Protocol
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- State University of New York at Buffalo
Pre-Eclampsia, HELLP Syndrome
PlacEntal Acute Atherosis RefLecting Subclinical Atherosclerosis
Pregnancy is considered a cardiovascular (CV) stress test, and complicated pregnancies are associated with an increased risk for cardiovascular disease (CVD) later in life.
- Conditions
- Pre-Eclampsia, HELLP Syndrome, Intrauterine Growth Restriction, Pregnancy
- Trial name
- PEARLS (NCT05500989)
- Where
- Netherlands
- Volunteers
- 226 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Morphine, Cesarean Section
Determining the Optimal Dose of Intrathecal Morphine for Post-Cesarean Analgesia
Using spinal or epidural anesthesia (known as neuraxial blocks) is the gold standard for pain control during childbirth, especially in cesarean sections (C-sections).
- Conditions
- Morphine, Cesarean Section, Postoperative Pain, Acute, Spinal Analgesia
- Trial name
- NCT07023497
- Testing
- Intrathecal morphine
- Where
- Greece
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Ioannina
Healthy Adult Volunteers
Ultra-Processed Foods and Appetite Regulation: Acute Effects Across Body Mass Index Categories
This study was planned to observe the acute effects of minimally processed and ultra-processed food (UPF) consumption on appetite in participants with normal body mass index (BMI) [BMI: 18.5-24.99 kg/m2] and overweight-obese (BMI…
- Trial name
- NCT06798220
- Testing
- Traditional Breakfast, UPF Breakfast
- Where
- Turkey (Türkiye)
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Ondokuz Mayıs University
Healthy
Effect of Spinal Ketorolac After Acute Opioid Exposure
This research study is being done because pain is a significant problem for patients with a variety of medical problems and following surgery or traumatic injury.
- Trial name
- NCT00693160
- Testing
- ketorolac, remifentanil, Capsaicin
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Wake Forest University
Acute Pain, Cesarean Delivery
NSS-Bridge Device for Post-Cesarean Delivery Pain
The current opioid epidemic has led to a renewed interest in exploring non-pharmacological techniques to treat post-operative pain.
- Trial name
- NCT03830307
- Testing
- NSS-2-Bridge
- Where
- United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Grace Lim, MD, MS
Pre Diabetes, Insulin Resistance
Exenatide and Weight Loss for Diabetes Prevention
Exenatide, a GLP-1 agonist approved for lowering blood glucose concentrations in patients with type 2 diabetes, has been associated with restoration of the first-phase insulin response when administered intravenously to patients…
- Trial name
- NCT02084654
- Testing
- Exenatide 5 and 10 mcg 2 times a day
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Stanford University
Multi-organ Failure After Severe Trauma
Metabolic Reprogramming in Renal Tubular Cells in Acute Kidney Injury Following Severe Trauma
Severe trauma remains the leading cause of death in people under 50, and is associated with high morbidity, including severe disability, with a substantial socio-economic impact.
- Trial name
- METAKIT (NCT06167512)
- Where
- 2 sites in France
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Migraine Headaches, Nausea
Haldol/Diphenhydramine Versus Metoclopramide/Diphenhydramine for Treatment of Acute Headache in the ED: A RCT
Haloperidol is known to be a safe alternative medication to control difficult pain, and has been shown effective when compared to placebo for controlling headaches.
- Conditions
- Migraine Headaches, Nausea, Restlessness
- Trial name
- NCT02098499
- Testing
- Haloperidol, Metoclopramide 10mg, Diphenhydramine
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- United States Naval Medical Center, Portsmouth
Multiple Sclerosis, Acute Relapsing, Multiple Sclerosis
5-HT7 Receptor Implication in Inflammatory Mechanisms in Multiple Sclerosis
Multiple Sclerosis is a chronic autoimmune disease associated with inflammatory response harmful for the Central Nervous System.
- Trial name
- 5-HTSEP (NCT04546698)
- Testing
- blood sampling
- Where
- France
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Régional d'Orléans
Acute Cholecystitis, Colorectal Cancer
Safety and Feasibility of ActivSightTM in Human
ActivSightTM combines an innovative form factor and proprietary software to deliver precise, objective, real-time visualization of blood flow and tissue perfusion intraoperatively for laparoscope-based surgery.
- Conditions
- Acute Cholecystitis, Colorectal Cancer, Diverticulitis, Colonic, Obesity, Morbid
- Trial name
- NCT04633512
- Testing
- ActivSight
- Where
- 3 sites in United States
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Activ Surgical
Acute Coronary Syndrome, Chest Pain
Comparison of Accelerated Diagnostic Pathways for Acute Chest Pain in Emergency Departments in the United Arab Emirates
This is a prospective four-site cohort study, which will accrue adults with symptoms concerning for acute coronary syndrome over a period of 12 months.
- Trial name
- NCT05532787
- Testing
- Application of acute chest pain risk stratification scores (HEART and EDACS)
- Where
- 5 sites in United Arab Emirates
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- Zayed Military Hospital
Obesity, Diabetes
The Acute Effect of Malt Extract Versus Sucrose on the Response of Glucose and Insulin, Subjective Appetite Sensations and ad Libitum Energy Intake
Sucrose is the most used sweetener in beverage and foods in Denmark. Other sweeteners with other composition and amount of carbohydrates could be of interest in order to decrease the glucose and insulin responses after intake of…
- Trial name
- Harboe (NCT01615081)
- Testing
- The acute effect of malt extract versus sucrose on the response of glucose and insulin, subjective appetite sensations and ad libitum energy intake
- Where
- Denmark
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Sciatica Acute, Lumbar Spinal Stenosis
Efficacy of M640 in Acute Lumbosacral Musculoskeletal Conditions.
The goal of this clinical trial is to learn if a modification to metaxalone 640 mg can reduce low back and leg pain. The participants will be 18 to 80 years old, healthy with newly occurring back or leg pain.
- Trial name
- NCT06157177
- Testing
- Metaxalone 640 mg Oral Tablet
- Where
- 24 sites in United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Primus Pharmaceuticals
Pain, Acute
Therapeutic Strategies During Exposure to Pain in an Experimental Design
The goal of the present study is to compare different therapeutic strategies (according to habituation model vs. according to the inhibitory learning approach) during exposure to thermal pain in an experimental design.
- Trial name
- NCT03146832
- Testing
- Exposure therapy (according to habituation approach), Exposure therapy (according to inhibitory learning approach)
- Where
- Germany
- Volunteers
- 139 people, healthy volunteers welcome
- Sponsor
- Philipps University Marburg
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.